Physiology and pathology of collagen receptors

Acta Physiologica

Volumn 190, Issue 3, 2007, Pages 179-187

  Popova, S N ^a   Lundgren Akerlund E ^b   Wiig, H ^a   Gullberg, D ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b Cartela AB   (Sweden)

Author keywords

10 1 integrin; 11 1 integrin; Collagen; Inflammation; Knockout mice

Indexed keywords

ALPHA1 INTEGRIN; ALPHA11BETA1 INTEGRIN; ALPHA2 INTEGRIN; BETA1 INTEGRIN; COLLAGEN RECEPTOR; INTEGRIN; INTEGRIN ALPHA 10; INTEGRIN ALPHA10 BETA1; INTEGRIN ALPHA11; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; CHROMOSOME 15; CHROMOSOME 9; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MOUSE; NONHUMAN; PATHOLOGY; PHYSIOLOGY; PRIORITY JOURNAL; REVIEW;

ANIMALS; INTEGRINS; RECEPTORS, COLLAGEN;

EID: 34250643243     PISSN: 17481708     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2007.01718.x     Document Type: Review

References (65)

1. Aszodi, A., Hunziker, E.B., Brakebusch, C. et al. 2003. β1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis. Genes Dev 17, 2465 2479.
2. Beertsen, W. Everts, V. 1990. Formation of acellular root cementum in relation to dental and non-dental hard tissues in the rat. J Dent Res 69, 1669 1673.
3. Beertsen, W. Hoeben, K.A. 1987. Movement of fibroblasts in the periodontal ligament of the mouse incisor is related to eruption. J Dent Res 66, 1006 1010.
4. Bengtsson, T., Camper, L., Schneller, M. et al. 2001. Characterization of the mouse integrin subunit α10 gene and comparison with its human homologue. Genomic structure, chromosomal localization and identification of splice variants. Matrix Biol 20, 565 576.
5. Bengtsson, T., Aszodi, A., Nicolae, C. et al. 2005. Loss of α10β1 integrin expression leads to moderate dysfunction of growth plate chondrocytes. J Cell Sci 118, 929 936.
6. Brown, D., Wagner, D., Li, X. et al. 1999. Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis. Development 126, 4317 4329.
7. Burn-Murdoch, R. 1990. The role of the vasculature in tooth eruption. Eur J Orthod 12, 101 108.
8. Camper, L., Hellman, U. Lundgren-Akerlund, E. 1998. Isolation, cloning, and sequence analysis of the integrin subunit α10, a β1-associated collagen binding integrin expressed on chondrocytes. J Biol Chem 273, 20383 20389.
9. Camper, L., Holmvall, K., Wangnerud, C. et al. 2001. Distribution of the collagen-binding integrin alpha10beta1 during mouse development. Cell Tissue Res 306, 107 116.
10. Chen, J., Diacovo, T.G., Grenache, D.G. et al. 2002. The α2 integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis. Am J Pathol 161, 337 344.
11. Cooke, M.E., Sakai, T. Mosher, D.F. 2000. Contraction of collagen matrices mediated by α2β1A and αvβ3 integrins. J Cell Sci 113, 2375 2383.
12. Cosgrove, D., Rodgers, K., Meehan, D. et al. 2000. Integrin α1β1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy. Am J Pathol 157, 1649 1659.
13. Cserjesi, P., Brown, D., Ligon, K.L. et al. 1995. Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Development 121, 1099 1110.
14. Edelson, B.T., Li, Z., Pappan, L.K. et al. 2004. Mast cell-mediated inflammatory responses require the α2β1 integrin. Blood 103, 2214 2220.
15. Edelson, B.T., Stricker, T.P., Li, Z. et al. 2006. Novel collectin/C1q receptor mediates mast cell activation and innate immunity. Blood 107, 143 150.
16. de Fougerolles, A.R., Sprague, A.G., Nickerson-Nutter, C.L. et al. 2000. Regulation of inflammation by collagen-binding integrins α1β1 and α2β1 in models of hypersensitivity and arthritis. J Clin Invest 105, 721 729.
17. Gardner, H., Kreidberg, J., Koteliansky, V. et al. 1996. Deletion of integrin α1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion. Dev Biol 175, 301 313.
18. Gardner, H., Broberg, A., Pozzi, A. et al. 1999. Absence of integrin α1β1 in the mouse causes loss of feedback regulation of collagen synthesis in normal and wounded dermis. J Cell Sci 112, 263 272.
19. Grenache, D.G., Zhang, Z., Wells, L.E. et al. 2007. Wound healing in the α2β1 integrin-deficient mouse: altered keratinocyte biology and dysregulated matrix metalloproteinase expression. J Invest Dermatol 127, 455 466.
20. Gullberg, D. 2003. Cell biology: the molecules that make muscle. Nature 424, 138 140.
21. Gullberg, D. Lundgren-Åkerlund, E. 2002. Collagen-binding I domain integrins - what do they do? Prog Histochem Cytochem 37, 3 54.
22. Gullberg, D., Tingstrom, A., Thuresson, A.C. et al. 1990. β1 integrin-mediated collagen gel contraction is stimulated by PDGF. Exp Cell Res 186, 264 272.
23. Gullberg, D., Gehlsen, K.R., Turner, D.C. et al. 1992. Analysis of α1β1, α2β1 and α3β1 integrins in cell-collagen interactions: identification of conformation dependent α1β1 binding sites in collagen type I. EMBO J 11, 3865 3873.
24. Gullberg, D., Velling, T., Sjoberg, G. et al. 1995. Up-regulation of a novel integrin alpha-chain (αmt) on human fetal myotubes. Dev Dyn 204, 57 65.
25. Hirsch, M.S., Lunsford, L.E., Trinkaus-Randall, V. et al. 1997. Chondrocyte survival and differentiation in situ are integrin mediated. Dev Dyn 210, 249 263.
26. Holtkotter, O., Nieswandt, B., Smyth, N. et al. 2002. Integrin α2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen. J Biol Chem 277, 10789 10794.
27. Huang, S. Ingber, D.E. 2005. Cell tension, matrix mechanics, and cancer development. Cancer Cell 8, 175 176.
28. Ingber, D.E. 2006. Cellular mechanotransduction: putting all the pieces together again. FASEB J 20, 811 827.
29. Jokinen, J., Dadu, E., Nykvist, P. et al. 2004. Integrin-mediated cell adhesion to type I collagen fibrils. J Biol Chem 279, 31956 31963.
30. Kapyla, J., Jaalinoja, J., Tulla, M. et al. 2004. The fibril-associated collagen IX provides a novel mechanism for cell adhesion to cartilaginous matrix. J Biol Chem 279, 51677 51687.
31. Knight, C.G., Morton, L.F., Onley, D.J. et al. 1998. Identification in collagen type I of an integrin α2β1-binding site containing an essential GER sequence. J Biol Chem 273, 33287 33294.
32. Lee, R.T., Berditchevski, F., Cheng, G.C. et al. 1995. Integrin-mediated collagen matrix reorganization by cultured human vascular smooth muscle cells. Circ Res 76, 209 214.
33. Lee, W., Sodek, J. McCulloch, C.A. 1996. Role of integrins in regulation of collagen phagocytosis by human fibroblasts. J Cell Physiol 168, 695 704.
34. Lehnert, K., Ni, J., Leung, E. et al. 1999. The integrin α10 subunit: expression pattern, partial gene structure, and chromosomal localization. Cytogenet Cell Genet 87, 238 244.
35. Liden, A., Berg, A., Nedrebo, T. et al. 2006. Platelet-derived growth factor BB-mediated normalization of dermal interstitial fluid pressure after mast cell degranulation depends on β3 but not β1 integrins. Circ Res 98, 635 641.
36. Lu, N., Heuchel, R., Barczyk, M. et al. 2006. Tandem Sp1/Sp3 sites together with an Ets-1 site cooperate to mediate α11 integrin chain expression in mesenchymal cells. Matrix Biol 25, 118 129.
37. Meek, K. Fullwood, N. 2001. Corneal and scleral collagens. Micron 32, 261 272.
38. Meyer, F.A. 1983. Macromolecular basis of globular protein exclusion and of swelling pressure in loose connective tissue (umbilical cord). Biochim Biophys Acta 755, 388 399.
39. Nykvist, P., Tu, H., Ivaska, J. et al. 2000. Distinct recognition of collagen subtypes by α1β1 and α2β1 integrins. α1β1 mediates cell adhesion to type XIII collagen. J Biol Chem 275, 8255 8261.
40. Popova, S.N., Rodriguez-Sanchez, B., Liden, A. et al. 2004. The mesenchymal α11β1 integrin attenuates PDGF-BB-stimulated chemotaxis of embryonic fibroblasts on collagens. Dev Biol 270, 427 442.
41. Popova, S.N., Barrzcyk, M., Tiger, C. et al. 2007. α11β1 integrin-dependent regulation of periodontal ligament function in the erupting mouse incisor. Mol Cell Biol. Epub ahead of print (April 2007).
42. Pozzi, A., Moberg, P.E., Miles, L.A. et al. 2000. Elevated matrix metalloprotease and angiostatin levels in integrin α1 knockout mice cause reduced tumor vascularization. Proc Natl Acad Sci USA 97, 2202 2207.
43. Ravanti, L., Heino, J., Lopez-Otin, C. et al. 1999. Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase. J Biol Chem 274, 2446 2455.
44. Reed, R.K., Rubin, K., Wiig, H. et al. 1992. Blockade of beta 1-integrins in skin causes edema through lowering of interstitial fluid pressure. Circ Res 71, 978 983.
45. Reed, R.K., Berg, A., Gjerde, E.A. et al. 2001. Control of interstitial fluid pressure: role of beta1-integrins. Semin Nephrol 21, 222 230.
46. Riikonen, T., Westermarck, J., Koivisto, L. et al. 1995. Integrin α2β1 is a positive regulator of collagenase (MMP-1) and collagen α 1(I) gene expression. J Biol Chem 270, 13548 13552.
47. Rodt, S.A., Ahlen, K., Berg, A. et al. 1996. A novel physiological function for platelet-derived growth factor-BB in rat dermis. J Physiol 495 (Pt 1 193 200.
48. Schwander, M., Leu, M., Stumm, M. et al. 2003. β1 integrins regulate myoblast fusion and sarcomere assembly. Dev Cell 4, 673 685.
49. Shakibaei, M. 1998. Inhibition of chondrogenesis by integrin antibody in vitro. Exp Cell Res 240, 95 106.
50. Siljander, P.R., Hamaia, S., Peachey, A.R. et al. 2004. Integrin activation state determines selectivity for novel recognition sites in fibrillar collagens. J Biol Chem 279, 47763 47772.
51. Silver, F.H., Siperko, L.M. Seehra, G.P. 2003. Mechanobiology of force transduction in dermal tissue. Skin Res Technol 9, 3 23.
52. Sund, M., Vaisanen, T., Kaukinen, S. et al. 2001. Distinct expression of type XIII collagen in neuronal structures and other tissues during mouse development. Matrix Biol 20, 215 231.
53. Swiderski, R.E., Daniels, K.J., Jensen, K.L. et al. 1994. Type II collagen is transiently expressed during avian cardiac valve morphogenesis. Dev Dyn 200, 294 304.
54. Tiger, C.-F., Fougerousse, F., Grundström, G. et al. 2001. α11β1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal non-muscle cells. Dev Biol 237, 116 129.
55. Tulla, M., Pentikainen, O.T., Viitasalo, T. et al. 2001. Selective binding of collagen subtypes by integrin α1I, α2I, and α10I domains. J Biol Chem 276, 48206 48212.
56. Velling, T., Kusche-Gullberg, M., Sejersen, T. et al. 1999. cDNA cloning and chromosomal localization of human α11 integrin. A collagen-binding, I domain-containing, β1-associated integrin α-chain present in muscle tissues. J Biol Chem 274, 25735 25742.
57. Velling, T., Risteli, J., Wennerberg, K. et al. 2002. Polymerization of type I and III collagens is dependent on fibronectin and enhanced by integrins α11β1 and α2β1. J Biol Chem 277, 37377 37381.
58. Vogel, W., Brakebusch, C., Fassler, R. et al. 2000. Discoidin domain receptor 1 is activated independently of β1 integrin. J Biol Chem 275, 5779 5784.
59. Wang, K.K., Liu, N., Radulovich, N. et al. 2002. Novel candidate tumor marker genes for lung adenocarcinoma. Oncogene 21, 7598 7604.
60. Wang, C.Z., Su, H.W., Hsu, Y.C. et al. 2006. A discoidin domain receptor 1/SHP-2 signaling complex inhibits α2β1-integrin-mediated signal transducers and activators of transcription 1/3 activation and cell migration. Mol Biol Cell 17, 2839 2852.
61. Wenke, A.K., Rothhammer, T., Moser, M. et al. 2006. Regulation of integrin alpha10 expression in chondrocytes by the transcription factors AP-2epsilon and Ets-1. Biochem Biophys Res Commun 345, 495 501.
62. Wiig, H., Rubin, K. Reed, R.K. 2003. New and active role of the interstitium in control of interstitial fluid pressure: potential therapeutic consequences. Acta Anaesthesiol Scand 47, 111 121.
63. Zhang, W.-M., Bergman, C., Velling, T. et al. 2002. Analysis of the human integrin α11 gene (ITGA11) and its promoter. Matrix Biol 21, 513 523.
64. Zhang, W.M., Kapyla, J., Puranen, J.S. et al. 2003. α11β1 integrin recognizes the GFOGER sequence in interstitial collagens. J Biol Chem 278, 7270 7277.
65. Zweers, M.C., Davidson, J.M., Pozzi, A. et al. 2007. Integrin α2β1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization. J Invest Dermatol 127, 467 478.