Identification of an amiloride binding domain within the α-subunit of the epithelial Na+ channel

Journal of Biological Chemistry

Volumn 272, Issue 34, 1997, Pages 21075-21083

  Ismailov, Iskander I ^a,b   Kieber Emmons, Thomas ^b   Lin, Chaomei ^b   Berdiev, Bakhram K ^a,b   Shlyonsky, Vadim Gh ^a,b   Patton, Holly K ^a,b   Fuller, Catherine M ^a,b   Worrell, Roger ^c   Zuckerman, Jonathan B ^b   Sun, Weijing ^e   Eaton, Douglas C ^c   Benos, Dale J ^a,b   Kleyman, Thomas R ^b,d  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c EMORY UNIVERSITY   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; SODIUM CHANNEL;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; ENZYME SUBSTRATE; EPITHELIUM CELL; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SECOND MESSENGER; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

ACTINS; AMILORIDE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; ELECTRIC CONDUCTIVITY; EPITHELIUM; HISTIDINE; IMMUNOLOGIC TECHNIQUES; ION CHANNEL GATING; LIPID BILAYERS; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; RECOMBINANT PROTEINS; SEQUENCE DELETION; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

ANIMALIA;

EID: 0030845222     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.34.21075     Document Type: Article

References (43)

1. Kleyman, T. R., and Cragoe, E. J., Jr. (1990) Methods Enzymol. 191, 739-755
2. Waldmann, R., Champigny, G., and Lazdunski, M. (1995) J. Biol. Chem. 270, 11735-11737
3. Canessa, C. M., Schild, L., Buell, G., Thorens, B., Gautschl, I., Horisberger, J.-D., and Rossier, B. C. (1994) Nature 367, 463-467
4. Schild, L., Schneeberger, E., Gautschil, I., and Firsov, D. (1997) J. Gen. Physiol. 109, 15-26
5. Fuller, C. M., Berdiev, B. K., Shlyonsky, V. G., Ismailov, I. I., and Benos, D. J. (1997) Biophys. J. 72, 1622-1632
6. Li, X. J., Xu, R. H., Guggino, W. B., and Snyder, S. H. (1995) Mol. Pharmacol. 47, 1133-1140
7. Counillon, L., Franchi, A., and Pouyssegur, J. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 4508-4512
8. Yun, C. H., Little, P. J., Nath, S. K., Levine, S. A., Pouyssegur, J., Tse, C. M., and Donowitz, M. (1993) Biochem. Biophys. Res. Commun. 193, 532-539
9. Kleyman, T. R., Rajagopalan, R., Cragoe, E. J., Jr., Erlanger, B. F., and Al-Awqati, Q. (1986) Am. J. Physiol. 250, C165-C170
10. Kleyman, T. R., Kraehenbuhl, J. P., Rossier, B. C., Cragoe, E. J. J., and Warnock, D. G. (1989) Am. J. Physiol. 257, C1135-C1141
11. Kleyman, T. R., and Zebrowitz, J. (1991) Am. J. Physiol. 260, C271-C276
12. Lin, C., Kieber-Emmons, T., Villalobos, A. P., Foster, M. H., Wahlgren, C., and Kleyman, T. R. (1994) J. Biol. Chem. 269, 2805-2813
13. Kieber-Emmons, T., Lin, C., Prammer, K., Villalobos, A., Kosari, F., and Kleyman, T. R. (1995) Kidney Int. 48, 956-964
14. Sanger, F. G., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
15. Fuller, C. M., Awayda, M. S., Arrate, M. P., Bradford, A. L., Morris, R. G., Canessa, C. M., Rossier, B. C., and Benos, D. J. (1995) Am. J. Physiol. 269, C641-C654
16. Awayda, M. S., Ismailov, I. I., Berdiev, B. K., Fuller, C. M., and Benos, D. J. (1996) J. Gen. Physiol. 108, 49-65
17. Ismailov, I. I., Awayda, M. S., Berdiev, B. K., Bubien, J. K., Lucas, J. E., Fuller, C. M., and Benos, D. J. (1996) J. Biol. Chem. 271, 807-816
18. Berdiev, B. K., Prat, A. G., Cantiello, H. F., Ausiello, D. A., Fuller, C. M., Jovov, B., Benos, D. J., and Ismailov, I. I. (1996) J. Biol. Chem. 271, 17704-17710
19. Canessa, C. M., Horisberger, J.-D., and Rossier, B. C. (1993) Nature 361, 467-470
20. Renard, S., Lingueglia, E., Voilley, N., Lazdunski, M., and Barbry, P. (1994) J. Biol. Chem. 269, 12981-12986
21. Canessa, C. M., Merillat, A. M., and Rossier, B. C. (1994) Am. J. Physiol. 267, C1682-C1690
22. Snyder, P. M., McDonald, F. J., Stokes, J. B., and Welsh, M. J. (1994) J. Biol. Chem. 269, 24379-24383
23. Busch, A. E., Suessbrich, H., Kunzelmann, K., Hipper, A., Greger, R., Waldegger, S., Mutschler, E., Lindemann, B., and Lang, F. (1996) Pflugers Arch. Eur. J. Physiol. 432, 760-766
24. Palmer, L. G. (1992) Annu. Rev. Physiol. 54, 51-66
25. Almers, W., and McCleskey, E. W. (1984) J. Physiol. 353, 585-608
26. Hille, B., and Schwartz, W. (1978) J. Gen. Physiol. 72, 409-442
27. Myers, V. B., and Haydon, D. A. (1972) Biochim. Biophys. Acta 274, 313-322
28. Ismailov, I. I., Shlyonsky, V. G., Alvarez, O., and Benos, D. J. (1997) J. Physiol., in press
29. Benos, D. J., Awayda, M.S., Ismailov, I. I., and Johnson, J. P. (1995) J. Membr. Biol. 143, 1-18
30. Shimkets, R. A., Warnock, D. G., Bositis, C. M., Nelson-Williams, C., Hansson, J. H., Schambelan, M., Gill, J. R., Jr., Ulick, S., Milora, R. V., Findling, J. W., Canessa, C. M., Rossier, B. C., and Lifton, R. P. (1994) Cell 79, 407-414
31. Hamilton, K. L., and Eaton, D. C. (1985) Am. J. Physiol. 249, C200-C207
32. Warncke, J., and Lindemann, B. (1985) J. Membr. Biol. 86, 255-265
33. Gottlieb, G. P., Turnheim, K., Frizzell, R. A., and Schultz, S. G. (1978) Biophys. J. 22, 125-129
34. Palmer, L. G. (1984) J. Membr. Biol. 80, 153-165
35. Li, J. H.-Y., and Lindemann, B. (1982) in Basic Mechanisms in the Action of Lithium (Emrich, H. M., Aldenhoff, J. B., and Lux, H. D., ed) pp. 28-35, Excerpta Medica, Amsterdam
36. Van Driessche, W., and Erlij, P. (1983) Pfluegers Arch. 398, 179-188
37. Balaban, R. S., Mandel, L. J., and Benos, D. J. (1979) J. Membr. Biol. 49, 363-390
38. Li, J. H.-Y., Cragoe, E. J., Jr., and Lindemann, B. (1985) J. Membr. Biol. 83, 45-56
39. Voilley, N., Lingueglia, E., Champigny, G., Mattei, M. G., Waldmann, R., Lazdunski, M., and Barbry, P. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 247-251
40. Puoti, A., May, A., Canessa, C. M., Horisberger, J. D., Schild, L., and Rossier, B. C. (1995) Am. J. Physiol. 269, C188-C197
41. Ahn, Y. J., Brooker, D. R., Harte, B. J., Smith, P. R., Zuckerman, J. B., Kosari, F., Mackler, S. A., and Kleyman, T. R. (1996) J. Am. Soc. Nephrol. 7, 1275 (abstr.)
42. Waldmann, R., Champigny, G., Bassilana, F., Voilley, N., and Lazdunski, M. (1995) J. Biol. Chem. 270, 27411-27414
43. Lingueglia, E., Champigny, G., Lazdunski, M., and Barbry, P. (1995) Nature 378, 730-733