Predictive computational models of substrate binding by a nucleoside transporter

Journal of Biological Chemistry

Volumn 284, Issue 49, 2009, Pages 34028-34035

  Collar, Catherine J ^a   Al Salabi, Mohammed I ^b   Stewart, Mhairi L ^b   Barrett, Michael P ^b   Wilson, W David ^a   de Koning, Harry P ^a,b  

^a GEORGIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPURINE; COMPOUND STRUCTURES; COMPUTATIONAL BIOLOGY; COMPUTATIONAL MODEL; DATA SETS; FOOD AND DRUG ADMINISTRATION; INHIBITION CONSTANTS; MELARSOPROL; MOLECULAR BASIS; NUCLEOSIDE TRANSPORTERS; PHARMACOPHORES; PREDICTIVE TOOLS; PRIMARY SEQUENCES; RESISTANCE MECHANISMS; STRUCTURAL CHARACTERISTICS; SUBSTRATE BINDING; TRANSPORT PROTEINS; TRYPANOSOMA BRUCEI;

BIOINFORMATICS; MOLECULAR BIOLOGY;

MOLECULAR RECOGNITION;

2,4 DIAMINOPYRIMIDINE DERIVATIVE; DIAMIDINE DERIVATIVE; FURAMIDINE; MELARSOPROL; NUCLEOSIDE TRANSPORTER; PENTAMIDINE; STILBAMIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPUTER PREDICTION; ENZYME SUBSTRATE COMPLEX; FEMALE; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; COMPUTATIONAL BIOLOGY; COMPUTERS; DRUG DESIGN; FEMALE; KINETICS; MELARSOPROL; NUCLEOSIDE TRANSPORT PROTEINS; PENTAMIDINE; RATS; RATS, WISTAR; SOFTWARE; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

TRYPANOSOMA BRUCEI;

EID: 71749098789     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.049726     Document Type: Article

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