Mapping of ligand-binding covities in proteins

Proteins: Structure, Function and Bioinformatics

Volumn 78, Issue 6, 2010, Pages 1408-1422

  David Andersson, C ^a   Chen, Brian Y ^b   Linusson, Anna ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Alignment independent; Binding sites; Bioinformatics; Drug design; Medicinal chemistry; PCA clustering tree; Physicochemical properties; Principal component analysis; Protein cavity comparison; Screen

Indexed keywords

SERINE PROTEINASE;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; GENE MUTATION; LIGAND BINDING; MOLECULAR MODEL; PREDICTION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; DATABASES, PROTEIN; HUMANS; LIGANDS; PEPTIDE HYDROLASES; PRINCIPAL COMPONENT ANALYSIS; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 77951210909     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22655     Document Type: Article

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