메뉴 건너뛰기




Volumn 32, Issue 3, 2010, Pages 313-328

Behavioral toxicology in the 21st century: Challenges and opportunities for behavioral scientists. Summary of a symposium presented at the annual meeting of the Neurobehavioral Teratology Society, June, 2009

Author keywords

Alternative methods; Behavioral toxicology; Narcosis pathway; Phthalates; Risk assessment; Thyroid hormone pathway; Toxicity pathway; Toxicity testing

Indexed keywords

ANESTHETIC AGENT; CHLORPYRIFOS; PHOSALONE; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PHTHALIC ACID DERIVATIVE; PHTHALIC ACID DIBUTYL ESTER; SOLVENT; THYROID HORMONE; TOLUENE; VINCLOZOLIN;

EID: 77951205036     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ntt.2010.02.002     Document Type: Article
Times cited : (34)

References (91)
  • 1
    • 33748945160 scopus 로고    scopus 로고
    • A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl)-phthalate (DEHP): non-monotonic dose-response and low dose effects on rat brain aromatase activity
    • Andrade A.J., Grande S.W., Talsness C.E., Grote K., Chahoud I. A dose-response study following in utero and lactational exposure to di-(2-ethylhexyl)-phthalate (DEHP): non-monotonic dose-response and low dose effects on rat brain aromatase activity. Toxicology 2006, 227:185-192.
    • (2006) Toxicology , vol.227 , pp. 185-192
    • Andrade, A.J.1    Grande, S.W.2    Talsness, C.E.3    Grote, K.4    Chahoud, I.5
  • 2
    • 73649102067 scopus 로고    scopus 로고
    • Introduction to the special issue on emerging high throughput and complementary model screens for neurotoxicology
    • Aschner M., Crofton K.M., Levin E.D. Introduction to the special issue on emerging high throughput and complementary model screens for neurotoxicology. Neurotoxicol. Teratol. 2010, 32:1-3.
    • (2010) Neurotoxicol. Teratol. , vol.32 , pp. 1-3
    • Aschner, M.1    Crofton, K.M.2    Levin, E.D.3
  • 3
    • 18844404906 scopus 로고    scopus 로고
    • Volatile organic compounds inhibit human and rat neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes
    • Bale A.S., Meacham C.A., Benignus V.A., Bushnell P.J., Shafer T.J. Volatile organic compounds inhibit human and rat neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. Toxicol. Appl. Pharmacol. 2005, 205:77-88.
    • (2005) Toxicol. Appl. Pharmacol. , vol.205 , pp. 77-88
    • Bale, A.S.1    Meacham, C.A.2    Benignus, V.A.3    Bushnell, P.J.4    Shafer, T.J.5
  • 4
    • 0031903987 scopus 로고    scopus 로고
    • A dosimetric analysis of behavioral effects of acute toluene exposure in rats and humans
    • Benignus V.A., Boyes W.K., Bushnell P.J. A dosimetric analysis of behavioral effects of acute toluene exposure in rats and humans. Toxicol. Sci. 1998, 43:186-195.
    • (1998) Toxicol. Sci. , vol.43 , pp. 186-195
    • Benignus, V.A.1    Boyes, W.K.2    Bushnell, P.J.3
  • 5
    • 18644367160 scopus 로고    scopus 로고
    • Toward cost-benefit analysis of acute behavioral effects of toluene in humans
    • Benignus V.A., Bushnell P.J., Boyes W.K. Toward cost-benefit analysis of acute behavioral effects of toluene in humans. Risk Anal. 2005, 25:447-456.
    • (2005) Risk Anal. , vol.25 , pp. 447-456
    • Benignus, V.A.1    Bushnell, P.J.2    Boyes, W.K.3
  • 6
    • 19044397233 scopus 로고    scopus 로고
    • Human neurobehavioral effects of long-term exposure to styrene: a meta-analysis
    • Benignus V.A., Geller A.M., Boyes W.K., Bushnell P.J. Human neurobehavioral effects of long-term exposure to styrene: a meta-analysis. Environ. Health Perspect. 2005, 113:532-538.
    • (2005) Environ. Health Perspect. , vol.113 , pp. 532-538
    • Benignus, V.A.1    Geller, A.M.2    Boyes, W.K.3    Bushnell, P.J.4
  • 7
    • 30744436318 scopus 로고    scopus 로고
    • A general physiological and toxicokinetic (GPAT) model for simulating complex toluene exposure scenarios in humans
    • Benignus V.A., Coleman T., Eklund C., Kenyon E.M. A general physiological and toxicokinetic (GPAT) model for simulating complex toluene exposure scenarios in humans. Toxicol. Mech. Meth. 2006, 16:27-33.
    • (2006) Toxicol. Mech. Meth. , vol.16 , pp. 27-33
    • Benignus, V.A.1    Coleman, T.2    Eklund, C.3    Kenyon, E.M.4
  • 8
    • 35448989847 scopus 로고    scopus 로고
    • Quantitative comparisons of the acute neurotoxicity of toluene in rats and humans
    • Benignus V.A., Boyes W.K., Kenyon E.M., Bushnell P.J. Quantitative comparisons of the acute neurotoxicity of toluene in rats and humans. Toxicol. Sci. 2007, 100:146-155.
    • (2007) Toxicol. Sci. , vol.100 , pp. 146-155
    • Benignus, V.A.1    Boyes, W.K.2    Kenyon, E.M.3    Bushnell, P.J.4
  • 12
    • 33751546329 scopus 로고    scopus 로고
    • The last decade of solvent research in animal models of abuse: mechanistic and behavioral studies
    • Bowen S.E., Batis J.C., Paez-Martinez N., Cruz S.L. The last decade of solvent research in animal models of abuse: mechanistic and behavioral studies. Neurotoxicol. Teratol. 2006, 28:636-647.
    • (2006) Neurotoxicol. Teratol. , vol.28 , pp. 636-647
    • Bowen, S.E.1    Batis, J.C.2    Paez-Martinez, N.3    Cruz, S.L.4
  • 13
    • 0027308928 scopus 로고
    • Endemic cretinism: toward a unifying hypothesis
    • Boyages S.C., Halpern J.P. Endemic cretinism: toward a unifying hypothesis. Thyroid 1993, 3:59-69.
    • (1993) Thyroid , vol.3 , pp. 59-69
    • Boyages, S.C.1    Halpern, J.P.2
  • 15
    • 0033766489 scopus 로고    scopus 로고
    • Tissue-specific actions of thyroid hormone: insights from animal models
    • Brent G.A. Tissue-specific actions of thyroid hormone: insights from animal models. Rev. Endocr. Metab. Disord. 2000, 1:27-33.
    • (2000) Rev. Endocr. Metab. Disord. , vol.1 , pp. 27-33
    • Brent, G.A.1
  • 16
    • 0031787160 scopus 로고    scopus 로고
    • Effects of environmental synthetic chemicals on thyroid function
    • Brucker-Davis F. Effects of environmental synthetic chemicals on thyroid function. Thyroid 1998, 8:827-856.
    • (1998) Thyroid , vol.8 , pp. 827-856
    • Brucker-Davis, F.1
  • 17
    • 17044409723 scopus 로고    scopus 로고
    • Development and applications of an exposure-dose-response model for organic solvents
    • Bushnell P.J., Shafer T.J., Bale A.S., Boyes W.K. Development and applications of an exposure-dose-response model for organic solvents. Environ. Toxicol. Pharmacol. 2005, 19:607-614.
    • (2005) Environ. Toxicol. Pharmacol. , vol.19 , pp. 607-614
    • Bushnell, P.J.1    Shafer, T.J.2    Bale, A.S.3    Boyes, W.K.4
  • 20
    • 0031053510 scopus 로고    scopus 로고
    • Mechanistic data and risk assessment of selected toxic end points of the thyroid gland
    • Capen C.C. Mechanistic data and risk assessment of selected toxic end points of the thyroid gland. Toxicol. Pathol. 1997, 25:39-48.
    • (1997) Toxicol. Pathol. , vol.25 , pp. 39-48
    • Capen, C.C.1
  • 21
    • 0033177872 scopus 로고    scopus 로고
    • Evaluation of the uncertainty in an oral reference dose for methylmercury due to interindividual variability in pharmacokinetics
    • Clewell H.J., Gearhart J.M., Gentry P.R., Covington T.R., VanLandingham C.B., Crump K.S., Shipp A.M. Evaluation of the uncertainty in an oral reference dose for methylmercury due to interindividual variability in pharmacokinetics. Risk Anal. 1999, 19:547-558.
    • (1999) Risk Anal. , vol.19 , pp. 547-558
    • Clewell, H.J.1    Gearhart, J.M.2    Gentry, P.R.3    Covington, T.R.4    VanLandingham, C.B.5    Crump, K.S.6    Shipp, A.M.7
  • 23
    • 11344278663 scopus 로고    scopus 로고
    • Developmental disruption of thyroid hormone: correlations with hearing dysfunction in rats
    • Crofton K.M. Developmental disruption of thyroid hormone: correlations with hearing dysfunction in rats. Risk Anal. 2004, 24:1665-1671.
    • (2004) Risk Anal. , vol.24 , pp. 1665-1671
    • Crofton, K.M.1
  • 24
    • 40349101820 scopus 로고    scopus 로고
    • Thyroid disrupting chemicals: mechanisms and mixtures
    • Crofton K.M. Thyroid disrupting chemicals: mechanisms and mixtures. Int. J. Androl. 2008, 31:209-223.
    • (2008) Int. J. Androl. , vol.31 , pp. 209-223
    • Crofton, K.M.1
  • 25
    • 28144457621 scopus 로고    scopus 로고
    • Mode of action: neurotoxicity induced by thyroid hormone disruption during development - hearing loss resulting from exposure to PHAHs
    • Crofton K.M., Zoeller R.T. Mode of action: neurotoxicity induced by thyroid hormone disruption during development - hearing loss resulting from exposure to PHAHs. Crit. Rev. Toxicol. 2005, 35:757-769.
    • (2005) Crit. Rev. Toxicol. , vol.35 , pp. 757-769
    • Crofton, K.M.1    Zoeller, R.T.2
  • 26
    • 0031871151 scopus 로고    scopus 로고
    • Effects of the abused solvent toluene on recombinant N-methyl-d-aspartate and non-N-methyl-d-aspartate receptors expressed in Xenopus oocytes
    • Cruz S.L., Mirshahi T., Thomas B., Balster R.L., Woodward J.J. Effects of the abused solvent toluene on recombinant N-methyl-d-aspartate and non-N-methyl-d-aspartate receptors expressed in Xenopus oocytes. J. Pharmacol. Exp. Ther. 1998, 286:334-340.
    • (1998) J. Pharmacol. Exp. Ther. , vol.286 , pp. 334-340
    • Cruz, S.L.1    Mirshahi, T.2    Thomas, B.3    Balster, R.L.4    Woodward, J.J.5
  • 34
    • 0021248347 scopus 로고
    • Phthalate esters and their effect on the liver
    • Ganning A.E., Brunk U., Dallner G. Phthalate esters and their effect on the liver. Hepatology 1984, 4:541-547.
    • (1984) Hepatology , vol.4 , pp. 541-547
    • Ganning, A.E.1    Brunk, U.2    Dallner, G.3
  • 35
    • 0022924244 scopus 로고
    • Sexual differentiation of the brain: a model for drug-induced alterations of the reproductive system
    • Gorski R.A. Sexual differentiation of the brain: a model for drug-induced alterations of the reproductive system. Environ. Health Perspect. 1986, 70:163-175.
    • (1986) Environ. Health Perspect. , vol.70 , pp. 163-175
    • Gorski, R.A.1
  • 36
    • 0029020542 scopus 로고
    • A physiologically based pharmacokinetic model for methyl mercury in the pregnant rat and fetus
    • Gray D.G. A physiologically based pharmacokinetic model for methyl mercury in the pregnant rat and fetus. Toxicol. Appl. Pharmacol. 1995, 132:91-102.
    • (1995) Toxicol. Appl. Pharmacol. , vol.132 , pp. 91-102
    • Gray, D.G.1
  • 37
    • 0019280981 scopus 로고
    • Testicular atrophy produced by phthalate esters
    • Gray T.J., Butterworth K.R. Testicular atrophy produced by phthalate esters. Arch. Toxicol. Suppl. 1980, 4:452-455.
    • (1980) Arch. Toxicol. Suppl. , vol.4 , pp. 452-455
    • Gray, T.J.1    Butterworth, K.R.2
  • 39
    • 0017889812 scopus 로고
    • Safety evaluation of medical plastics
    • Guess W.L. Safety evaluation of medical plastics. Clin. Toxicol. 1978, 12:77-95.
    • (1978) Clin. Toxicol. , vol.12 , pp. 77-95
    • Guess, W.L.1
  • 43
    • 33750482232 scopus 로고    scopus 로고
    • Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites
    • Hauser R., Meeker J.D., Duty S., Silva M.J., Calafat A.M. Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites. Epidemiology (Cambridge, Mass) 2006, 17:682-691.
    • (2006) Epidemiology (Cambridge, Mass) , vol.17 , pp. 682-691
    • Hauser, R.1    Meeker, J.D.2    Duty, S.3    Silva, M.J.4    Calafat, A.M.5
  • 44
    • 49949094242 scopus 로고    scopus 로고
    • Is synergy the rule? A review of anesthetic interactions producing hypnosis and immobility
    • Hendrickx J.F., Eger E.I., Sonner J.M., Shafer S.L. Is synergy the rule? A review of anesthetic interactions producing hypnosis and immobility. Anesthes. Analg. 2008, 107:494-506.
    • (2008) Anesthes. Analg. , vol.107 , pp. 494-506
    • Hendrickx, J.F.1    Eger, E.I.2    Sonner, J.M.3    Shafer, S.L.4
  • 45
    • 31844443695 scopus 로고
    • The environment and disease: association or causation?
    • Section on Occupational Medicine Meeting January 14, 1965
    • Hill A.B. The environment and disease: association or causation?. Proc. Royal Soc. Med. 1965, 58:295-300. Section on Occupational Medicine Meeting January 14, 1965.
    • (1965) Proc. Royal Soc. Med. , vol.58 , pp. 295-300
    • Hill, A.B.1
  • 47
    • 1342309163 scopus 로고    scopus 로고
    • Sex steroids and human behavior: prenatal androgen exposure and sex-typical play behavior in children
    • Hines M. Sex steroids and human behavior: prenatal androgen exposure and sex-typical play behavior in children. Annal. N. Y. Acad. Sci. 2003, 1007:272-282.
    • (2003) Annal. N. Y. Acad. Sci. , vol.1007 , pp. 272-282
    • Hines, M.1
  • 48
    • 67649224663 scopus 로고    scopus 로고
    • Interference of endocrine disrupters with thyroid hormone receptor-dependent transactivation
    • Hofmann P.J., Schomburg L., Kohrle J. Interference of endocrine disrupters with thyroid hormone receptor-dependent transactivation. Toxicol. Sci. 2009, 110:125-137.
    • (2009) Toxicol. Sci. , vol.110 , pp. 125-137
    • Hofmann, P.J.1    Schomburg, L.2    Kohrle, J.3
  • 49
    • 52949122185 scopus 로고    scopus 로고
    • Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats
    • Howdeshell K.L., Rider C.V., Wilson V.S., Gray L.E. Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats. Environ. Res. 2008, 108:168-176.
    • (2008) Environ. Res. , vol.108 , pp. 168-176
    • Howdeshell, K.L.1    Rider, C.V.2    Wilson, V.S.3    Gray, L.E.4
  • 50
    • 36649034008 scopus 로고    scopus 로고
    • Mapping gene expression changes in the fetal rat testis following acute dibutyl phthalate exposure defines a complex temporal cascade of responding cell types
    • Johnson K.J., Hensley J.B., Kelso M.D., Wallace D.G., Gaido K.W. Mapping gene expression changes in the fetal rat testis following acute dibutyl phthalate exposure defines a complex temporal cascade of responding cell types. Biol. Reprod. 2007, 77:978-989.
    • (2007) Biol. Reprod. , vol.77 , pp. 978-989
    • Johnson, K.J.1    Hensley, J.B.2    Kelso, M.D.3    Wallace, D.G.4    Gaido, K.W.5
  • 53
    • 67650729693 scopus 로고    scopus 로고
    • Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB
    • Knudsen T.B., Martin M.T., Kavlock R.J., Judson R.S., Dix D.J., Singh A.V. Profiling the activity of environmental chemicals in prenatal developmental toxicity studies using the U.S. EPA's ToxRefDB. Reprod. Toxicol. 2009, 28:209-219.
    • (2009) Reprod. Toxicol. , vol.28 , pp. 209-219
    • Knudsen, T.B.1    Martin, M.T.2    Kavlock, R.J.3    Judson, R.S.4    Dix, D.J.5    Singh, A.V.6
  • 55
    • 70349754491 scopus 로고    scopus 로고
    • Associations between indoor environmental factors and parental-reported autistic spectrum disorders in children 6-8years of age
    • Larsson M., Weiss B., Janson S., Sundell J., Bornehag C.G. Associations between indoor environmental factors and parental-reported autistic spectrum disorders in children 6-8years of age. Neurotoxicology 2009, 30:822-831.
    • (2009) Neurotoxicology , vol.30 , pp. 822-831
    • Larsson, M.1    Weiss, B.2    Janson, S.3    Sundell, J.4    Bornehag, C.G.5
  • 58
    • 64049119418 scopus 로고    scopus 로고
    • Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database
    • Martin M.T., Judson R.S., Reif D.M., Kavlock R.J., Dix D.J. Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database. Environ. Health Perspect. 2009, 117:392-399.
    • (2009) Environ. Health Perspect. , vol.117 , pp. 392-399
    • Martin, M.T.1    Judson, R.S.2    Reif, D.M.3    Kavlock, R.J.4    Dix, D.J.5
  • 59
    • 67649233774 scopus 로고    scopus 로고
    • Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database
    • Martin M.T., Mendez E., Corum D.G., Judson R.S., Kavlock R.J., Rotroff D.M., Dix D.J. Profiling the reproductive toxicity of chemicals from multigeneration studies in the toxicity reference database. Toxicol. Sci. 2009, 110:181-190.
    • (2009) Toxicol. Sci. , vol.110 , pp. 181-190
    • Martin, M.T.1    Mendez, E.2    Corum, D.G.3    Judson, R.S.4    Kavlock, R.J.5    Rotroff, D.M.6    Dix, D.J.7
  • 60
    • 0015496122 scopus 로고
    • Phthalic acid esters: biological impact uncertain
    • Marx J.L. Phthalic acid esters: biological impact uncertain. Science 1972, 178:46-47.
    • (1972) Science , vol.178 , pp. 46-47
    • Marx, J.L.1
  • 61
    • 67651112958 scopus 로고    scopus 로고
    • Urinary metabolites of di(2-ethylhexyl) phthalate are associated with decreased steroid hormone levels in adult men
    • Meeker J.D., Calafat A.M., Hauser R. Urinary metabolites of di(2-ethylhexyl) phthalate are associated with decreased steroid hormone levels in adult men. J. Androl. 2008.
    • (2008) J. Androl.
    • Meeker, J.D.1    Calafat, A.M.2    Hauser, R.3
  • 62
    • 0008245486 scopus 로고
    • Narcosis by inert gases under pressure, Hoppe-Seyler's Z
    • Meyer K.H., Hopff H. Narcosis by inert gases under pressure, Hoppe-Seyler's Z. Physiol. Chem. 1923, 126:288-298.
    • (1923) Physiol. Chem. , vol.126 , pp. 288-298
    • Meyer, K.H.1    Hopff, H.2
  • 63
    • 67650882534 scopus 로고    scopus 로고
    • Thyroid-disrupting chemicals: interpreting upstream biomarkers of adverse outcomes
    • Miller M.D., Crofton K.M., Rice D.C., Zoeller R.T. Thyroid-disrupting chemicals: interpreting upstream biomarkers of adverse outcomes. Environ. Health Perspect. 2009, 117:1033-1041.
    • (2009) Environ. Health Perspect. , vol.117 , pp. 1033-1041
    • Miller, M.D.1    Crofton, K.M.2    Rice, D.C.3    Zoeller, R.T.4
  • 64
    • 0031860360 scopus 로고    scopus 로고
    • Male reproductive tract malformations in rats following gestational and lactational exposure to Di(n-butyl) phthalate: an antiandrogenic mechanism?
    • Mylchreest E., Cattley R.C., Foster P.M. Male reproductive tract malformations in rats following gestational and lactational exposure to Di(n-butyl) phthalate: an antiandrogenic mechanism?. Toxicol. Sci. 1998, 43:47-60.
    • (1998) Toxicol. Sci. , vol.43 , pp. 47-60
    • Mylchreest, E.1    Cattley, R.C.2    Foster, P.M.3
  • 65
    • 0012567991 scopus 로고    scopus 로고
    • Neurophysiological effects of insecticides
    • Academic Press, San Diego, CA, R.I. Krieger (Ed.)
    • Narahashi T. Neurophysiological effects of insecticides. Handbook of Pesticide Toxicology 2001, 335-351. Academic Press, San Diego, CA. 2nd Edition. R.I. Krieger (Ed.).
    • (2001) Handbook of Pesticide Toxicology , pp. 335-351
    • Narahashi, T.1
  • 66
    • 77951209085 scopus 로고
    • NAS, Toxicity Testing: Strategies to Determine Needs and Priorities. National Academy of Sciences, National Research Council, National Academy Press, Washington DC., National Academy Press, Washington, DC, 1984.
    • NAS, Toxicity Testing: Strategies to Determine Needs and Priorities. National Academy of Sciences, National Research Council, National Academy Press, Washington DC., National Academy Press, Washington, DC, 1984.
    • (1984)
  • 68
    • 0034886771 scopus 로고    scopus 로고
    • High-throughput screening strategies for cardiac ion channels
    • Numann R., Negulescu P.A. High-throughput screening strategies for cardiac ion channels. Trends Cardiovasc. Med. 2001, 11:54-59.
    • (2001) Trends Cardiovasc. Med. , vol.11 , pp. 54-59
    • Numann, R.1    Negulescu, P.A.2
  • 69
    • 4344574333 scopus 로고    scopus 로고
    • Molecular and neuronal substrates for general anaesthetics
    • Rudolph U., Antkowiak B. Molecular and neuronal substrates for general anaesthetics. Nat. Rev. Neurosci. 2004, 5:709-720.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 709-720
    • Rudolph, U.1    Antkowiak, B.2
  • 72
    • 70350128794 scopus 로고    scopus 로고
    • A computational model reveals classical conditioning mechanisms underlying visual signal detection in rats
    • Schmajuk N.A., Bushnell P.J. A computational model reveals classical conditioning mechanisms underlying visual signal detection in rats. Behav. Process. 2009.
    • (2009) Behav. Process.
    • Schmajuk, N.A.1    Bushnell, P.J.2
  • 75
    • 27744586936 scopus 로고    scopus 로고
    • Perturbation of voltage-sensitive Ca2+ channel function by volatile organic solvents
    • Shafer T.J., Bushnell P.J., Benignus V.A., Woodward J.J. Perturbation of voltage-sensitive Ca2+ channel function by volatile organic solvents. J. Pharmacol. Exp. Ther. 2005, 315:1109-1118.
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , pp. 1109-1118
    • Shafer, T.J.1    Bushnell, P.J.2    Benignus, V.A.3    Woodward, J.J.4
  • 76
    • 49949097479 scopus 로고    scopus 로고
    • Additivity versus synergy: a theoretical analysis of implications for anesthetic mechanisms
    • Shafer S.L., Hendrickx J.F., Flood P., Sonner J., Eger E.I. Additivity versus synergy: a theoretical analysis of implications for anesthetic mechanisms. Anesthes. Analg. 2008, 107:507-524.
    • (2008) Anesthes. Analg. , vol.107 , pp. 507-524
    • Shafer, S.L.1    Hendrickx, J.F.2    Flood, P.3    Sonner, J.4    Eger, E.I.5
  • 77
    • 49249132006 scopus 로고    scopus 로고
    • "Additional" effects of phthalate mixtures on fetal testosterone production
    • Sharpe R.M. "Additional" effects of phthalate mixtures on fetal testosterone production. Toxicol. Sci. 2008, 105:1-4.
    • (2008) Toxicol. Sci. , vol.105 , pp. 1-4
    • Sharpe, R.M.1
  • 78
    • 0029551645 scopus 로고
    • Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production
    • Sharpe R.M., Fisher J.S., Millar M.M., Jobling S., Sumpter J.P. Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production. Environ. Health Perspect. 1995, 103:1136-1143.
    • (1995) Environ. Health Perspect. , vol.103 , pp. 1136-1143
    • Sharpe, R.M.1    Fisher, J.S.2    Millar, M.M.3    Jobling, S.4    Sumpter, J.P.5
  • 79
    • 0029551645 scopus 로고
    • Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production
    • Sharpe R.M., Fisher J.S., Millar M.M., Jobling S., Sumpter J.P. Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production. Environ. Health Perspect. 1995, 103:1136-1143.
    • (1995) Environ. Health Perspect. , vol.103 , pp. 1136-1143
    • Sharpe, R.M.1    Fisher, J.S.2    Millar, M.M.3    Jobling, S.4    Sumpter, J.P.5
  • 80
    • 35148860663 scopus 로고    scopus 로고
    • Carbamazepine and risk of hypothyroidism: a prospective study
    • Simko J., Horacek J. Carbamazepine and risk of hypothyroidism: a prospective study. Acta Neurol. Scand. 2007, 116:317-321.
    • (2007) Acta Neurol. Scand. , vol.116 , pp. 317-321
    • Simko, J.1    Horacek, J.2
  • 82
    • 34250184495 scopus 로고    scopus 로고
    • Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males
    • Stahlhut R.W., van Wijngaarden E., Dye T.D., Cook S., Swan S.H. Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males. Environ. Health Perspect. 2007, 115:876-882.
    • (2007) Environ. Health Perspect. , vol.115 , pp. 876-882
    • Stahlhut, R.W.1    van Wijngaarden, E.2    Dye, T.D.3    Cook, S.4    Swan, S.H.5
  • 83
    • 52949101044 scopus 로고    scopus 로고
    • Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans
    • Swan S.H. Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans. Environ. Res. 2008, 108:177-184.
    • (2008) Environ. Res. , vol.108 , pp. 177-184
    • Swan, S.H.1
  • 85
    • 0015537959 scopus 로고
    • Phthalic acid esters - an overview
    • Tepper L.B. Phthalic acid esters - an overview. Environ. Health Perspect. 1973, 3:179-182.
    • (1973) Environ. Health Perspect. , vol.3 , pp. 179-182
    • Tepper, L.B.1
  • 86
    • 0036883667 scopus 로고    scopus 로고
    • Toluene inhibits voltage-sensitive calcium channels expressed in pheochromocytoma cells
    • Tillar R., Shafer T.J., Woodward J.J. Toluene inhibits voltage-sensitive calcium channels expressed in pheochromocytoma cells. Neurochem. Int. 2002, 41:391-397.
    • (2002) Neurochem. Int. , vol.41 , pp. 391-397
    • Tillar, R.1    Shafer, T.J.2    Woodward, J.J.3
  • 87
    • 33644924900 scopus 로고    scopus 로고
    • Exploiting high-throughput ion channel screening technologies in integrated drug discovery
    • Treherne J.M. Exploiting high-throughput ion channel screening technologies in integrated drug discovery. Curr. Pharm. Des. 2006, 12:397-406.
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 397-406
    • Treherne, J.M.1
  • 88
    • 0025071340 scopus 로고
    • Rules for distinguishing toxicants that cause type I and type II narcosis syndromes
    • Veith G.D., Broderius S.J. Rules for distinguishing toxicants that cause type I and type II narcosis syndromes. Environ. Health Perspect. 1990, 87:207-211.
    • (1990) Environ. Health Perspect. , vol.87 , pp. 207-211
    • Veith, G.D.1    Broderius, S.J.2
  • 89
    • 39649085856 scopus 로고    scopus 로고
    • Neurobehavioral toxicology of pyrethroid insecticides in adult animals: a critical review
    • Wolansky M.J., Harrill J.A. Neurobehavioral toxicology of pyrethroid insecticides in adult animals: a critical review. Neurotoxicol. Teratol. 2008, 30:55-78.
    • (2008) Neurotoxicol. Teratol. , vol.30 , pp. 55-78
    • Wolansky, M.J.1    Harrill, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.