Chemotactic activation of Dictyostelium AGC-family kinases AKT and PKBR1 requires separate but coordinated functions of PDK1 and TORC2

Journal of Cell Science

Volumn 123, Issue 6, 2010, Pages 983-992

  Liao, Xin Hua ^a   Buggey, Jonathan ^a,b   Kimmel, Alan R ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BAR domains; Chemotaxis; PDK1; PH domains; PI3K PtdIns(3,4,5)P3; TORC2

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PHOSPHOTRANSFERASE; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE PKBR1; TORC2 KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; DICTYOSTELIUM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID MOTIFS; ANIMALS; CHEMOTACTIC FACTORS; CHEMOTAXIS; CYCLIC AMP; DICTYOSTELIUM; ENZYME ACTIVATION; FOLIC ACID; LIPID METABOLISM; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTOZOAN PROTEINS; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TRANS-ACTIVATORS;

DICTYOSTELIUM;

EID: 77951188014     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.064022     Document Type: Article

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