Characterization of the cloned full-length and a truncated human target of rapamycin: Activity, specificity, and enzyme inhibition as studied by a high capacity assay

Biochemical and Biophysical Research Communications

Volumn 332, Issue 1, 2005, Pages 304-310

  Toral Barza, Lourdes ^a   Zhang, Wei Guo ^a   Lamison, Craig ^a   LaRocque, James ^a   Gibbons, James ^a   Yu, Ker ^a  

^a WYETH RESEARCH   (United States)

Author keywords

Anticancer; High throughput screening; Kinase inhibitor; PIKK; Rapamycin; TOR

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; RAPAMYCIN; WORTMANNIN;

ARTICLE; CONTROLLED STUDY; DISSOCIATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SPECIFICITY; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNOASSAY; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; CLONING, MOLECULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; FLUORESCENCE POLARIZATION IMMUNOASSAY; KINETICS; PROTEIN KINASES; RECOMBINANT PROTEINS;

MAMMALIA;

EID: 19344375090     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.04.117     Document Type: Article

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