Targeting oxidative stress attenuates malonic acid induced Huntington like behavioral and mitochondrial alterations in rats

European Journal of Pharmacology

Volumn 634, Issue 1-3, 2010, Pages 46-52

  Kalonia, Harikesh ^a   Kumar, Puneet ^a   Kumar, Anil ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Huntington's disease; Malonic acid; Mitochondrial dysfunction; Oxidative stress; Striatum; Succinate dehydrogenase

Indexed keywords

ALPHA TOCOPHEROL; CATALASE; CYTOCHROME C OXIDASE; GLUTATHIONE; MALONIC ACID; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN INHIBITOR; MITOCHONDRIAL ENZYME; NITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; MALONIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; BODY WEIGHT; CONTROLLED STUDY; CORPUS STRIATUM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INHIBITION; HUNTINGTON CHOREA; LIPID PEROXIDATION; LOCOMOTION; MALE; MOTOR COORDINATION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ROTAROD TEST; WEIGHT CHANGE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; COMPARATIVE STUDY; DISEASE MODEL; DRUG DELIVERY SYSTEM; DRUG EFFECTS; HUNTINGTON DISEASE; METABOLISM; MITOCHONDRION; MOTOR ACTIVITY; PHYSIOLOGY; PROCEDURES; TOXICITY; WISTAR RAT;

ANIMALS; BODY WEIGHT; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; HUNTINGTON DISEASE; LIPID PEROXIDATION; MALE; MALONATES; MITOCHONDRIA; MOTOR ACTIVITY; OXIDATIVE STRESS; RATS; RATS, WISTAR; VITAMIN E;

EID: 77951178015     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.02.031     Document Type: Article

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