Protective effects of the antioxidant selenium on quinolinic acid-induced neurotoxicity in rats: In vitro and in vivo studies

Journal of Neurochemistry

Volumn 86, Issue 2, 2003, Pages 479-488

  Santamaría, Abel ^a,b   Salvatierra Sánchez, Raquel ^a   Vázquez Román, Beatriz ^a   Santiago López, Dario ^a   Villeda Hernández, Juana ^a   Galván Arzate, Sonia ^a   Jiménez Capdeville, María E ^a   Ali, Syed F ^b,c  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b Natl Ctr Toxicological Res F   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Antioxidant defense; Excitotoxin; N methyl D aspartate receptor; Neurotoxicity; Quinolinic acid; Selenium

Indexed keywords

4 AMINOBUTYRIC ACID; ANTIOXIDANT; FREE RADICAL; GLUTATHIONE PEROXIDASE; QUINOLINIC ACID; SELENATE;

4 AMINOBUTYRIC ACID BRAIN LEVEL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; LIQUID CHROMATOGRAPHY; LOCOMOTION; MALE; MORPHOLOGY; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ROTATION; STATISTICAL SIGNIFICANCE;

ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; BODY WEIGHT; BRAIN CHEMISTRY; CORPUS STRIATUM; GAMMA-AMINOBUTYRIC ACID; LIPID PEROXIDATION; MALE; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; QUINOLINIC ACID; RATS; RATS, WISTAR; SELENIUM; SODIUM SELENITE; SYNAPTOSOMES;

ANIMALIA; PRIMATES;

EID: 18244412070     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01857.x     Document Type: Article

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