메뉴 건너뛰기




Volumn 41, Issue 2, 2010, Pages 194-200

Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences

Author keywords

Aging; Genome wide methylation; Global hypomethylation; Interspersed repetitive sequences

Indexed keywords

ADULT; AGE; AGED; AGING; ALU SEQUENCE; ARTICLE; DNA METHYLATION; ENDOGENOUS RETROVIRUS; FEMALE; HUMAN; HUMAN CELL; HUMAN ENDOGENOUS RETROVIRUS K; INTERSPERSED REPEAT; LONG INTERSPERSED REPEAT; LONG INTERSPERSED REPEAT 1; LONG TERMINAL REPEAT; MALE; NONHUMAN; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RETROPOSON;

EID: 77951169806     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00146.2009     Document Type: Article
Times cited : (164)

References (62)
  • 1
    • 64049094851 scopus 로고    scopus 로고
    • Epigenetic therapies in haematological malignancies: Searching for true targets
    • Altucci L, Minucci S. Epigenetic therapies in haematological malignancies: searching for true targets. Eur J Cancer 45: 1137-1145, 2009.
    • (2009) Eur J Cancer , vol.45 , pp. 1137-1145
    • Altucci, L.1    Minucci, S.2
  • 3
    • 33646484146 scopus 로고    scopus 로고
    • Spontaneous micronuclei in cytokinesis-blocked bone marrow and peripheral blood lymphocytes of CML patients
    • Baser K, Sunguroglu A, Bokesoy I, Uysal A. Spontaneous micronuclei in cytokinesis-blocked bone marrow and peripheral blood lymphocytes of CML patients. Tr J Med Sci 29: 125-128, 1999.
    • (1999) Tr J Med Sci , vol.29 , pp. 125-128
    • Baser, K.1    Sunguroglu, A.2    Bokesoy, I.3    Uysal, A.4
  • 4
    • 0036250811 scopus 로고    scopus 로고
    • Alu repeats and human genomic diversity
    • Batzer MA, Deininger PL. Alu repeats and human genomic diversity. Nat Rev 3: 370-380, 2002.
    • (2002) Nat Rev , vol.3 , pp. 370-380
    • Batzer, M.A.1    Deininger, P.L.2
  • 5
    • 33646814901 scopus 로고    scopus 로고
    • Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells
    • Belgnaoui SM, Gosden RG, Semmes OJ, Haoudi A. Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells. Cancer Cell Intl 6: 1-10, 2006.
    • (2006) Cancer Cell Intl , vol.6 , pp. 1-10
    • Belgnaoui, S.M.1    Gosden, R.G.2    Semmes, O.J.3    Haoudi, A.4
  • 9
    • 33846639662 scopus 로고    scopus 로고
    • Hypermethylation of CpG island loci and hypomethylation of LINE-1 and Alu repeats in prostate adenocarcinoma and their relationship to clinicopathological features
    • Cho NY, Kim BH, Choi M, Yoo EJ, Moon KC, Cho YM, Kim D, Kang GH. Hypermethylation of CpG island loci and hypomethylation of LINE-1 and Alu repeats in prostate adenocarcinoma and their relationship to clinicopathological features. J Pathol 211: 269-277, 2007.
    • (2007) J Pathol , vol.211 , pp. 269-277
    • Cho, N.Y.1    Kim, B.H.2    Choi, M.3    Yoo, E.J.4    Moon, K.C.5    Cho, Y.M.6    Kim, D.7    Kang, G.H.8
  • 10
    • 34250645744 scopus 로고    scopus 로고
    • Hypomethylation of LINE-1 and Alu in well-differentiated neuroendocrine tumors (pancreatic endocrine tumors and carcinoid tumors)
    • Choi IS, Estecio MRH, Nagano Y, Kim DH, White JA, Yao JC, Issa JPJ, Rashid A. Hypomethylation of LINE-1 and Alu in well-differentiated neuroendocrine tumors (pancreatic endocrine tumors and carcinoid tumors). Mod Pathol 20: 802-810, 2007.
    • (2007) Mod Pathol , vol.20 , pp. 802-810
    • Choi, I.S.1    Estecio, M.R.H.2    Nagano, Y.3    Kim, D.H.4    White, J.A.5    Yao, J.C.6    Issa, J.P.J.7    Rashid, A.8
  • 15
    • 33748122556 scopus 로고    scopus 로고
    • Cancer-linked DNA hypomethylation and its relationship to hypermethylation
    • Ehrlich M. Cancer-linked DNA hypomethylation and its relationship to hypermethylation. Curr Top Microbiol Immunol 310: 251-274, 2006.
    • (2006) Curr Top Microbiol Immunol , vol.310 , pp. 251-274
    • Ehrlich, M.1
  • 19
    • 0032987773 scopus 로고    scopus 로고
    • DNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas
    • Flori AR, Lower R, Schmitz-Drager BJ, Schulz WA. DNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas. Br J Cancer 80: 1312-1321, 1999.
    • (1999) Br J Cancer , vol.80 , pp. 1312-1321
    • Flori, A.R.1    Lower, R.2    Schmitz-Drager, B.J.3    Schulz, W.A.4
  • 21
    • 64049097640 scopus 로고    scopus 로고
    • The promises and pitfalls of epigenetic therapies in solid tumours
    • Graham JS, Kaye SB, Brown R. The promises and pitfalls of epigenetic therapies in solid tumours. Eur J Cancer 45: 1129-1136, 2009.
    • (2009) Eur J Cancer , vol.45 , pp. 1129-1136
    • Graham, J.S.1    Kaye, S.B.2    Brown, R.3
  • 22
    • 40649093505 scopus 로고    scopus 로고
    • The relationship between 8-oxo-7,8-dihydro-2′-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas
    • Guz J, Foksinski M, Siomek A, Gackowski D, Rozalski R, Dziaman T, Szpila A, Olinski R. The relationship between 8-oxo-7,8-dihydro-2′-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas. Mutat Res 640: 170-173, 2008.
    • (2008) Mutat Res , vol.640 , pp. 170-173
    • Guz, J.1    Foksinski, M.2    Siomek, A.3    Gackowski, D.4    Rozalski, R.5    Dziaman, T.6    Szpila, A.7    Olinski, R.8
  • 23
    • 0024802174 scopus 로고
    • Age-related methylation changes in DNA may reflect the proliferative potential of organs
    • Hoal-van Helden EG, Van Helden PD. Age-related methylation changes in DNA may reflect the proliferative potential of organs. Mutat Res 219: 263-266, 1989.
    • (1989) Mutat Res , vol.219 , pp. 263-266
    • Hoal-Van Helden, E.G.1    Van Helden, P.D.2
  • 24
    • 24744471011 scopus 로고    scopus 로고
    • Causes and consequences of DNA hypomethylation in human cancer
    • Hoffmann MJ, Schulz WA. Causes and consequences of DNA hypomethylation in human cancer. Biochem Cell Biol 83: 296-321, 2005.
    • (2005) Biochem Cell Biol , vol.83 , pp. 296-321
    • Hoffmann, M.J.1    Schulz, W.A.2
  • 27
    • 0032845215 scopus 로고    scopus 로고
    • Aging, DNA methylation and cancer
    • Issa JP. Aging, DNA methylation and cancer. Crit Rev Oncol/Hematol 32: 31-43, 1999.
    • (1999) Crit Rev Oncol/Hematol , vol.32 , pp. 31-43
    • Issa, J.P.1
  • 28
    • 0037301560 scopus 로고    scopus 로고
    • Origin of a substantial fraction of human regulatory sequences from transposable elements
    • Jordan K, Rogozin IB, Glazko GV, Koonin EV. Origin of a substantial fraction of human regulatory sequences from transposable elements. Trends Genet 19: 68-72, 2003.
    • (2003) Trends Genet , vol.19 , pp. 68-72
    • Jordan, K.1    Rogozin, I.B.2    Glazko, G.V.3    Koonin, E.V.4
  • 29
    • 17344370076 scopus 로고    scopus 로고
    • The impact of L1 retrotransposons on the human genome
    • Kazazian HH Jr, Moran JV. The impact of L1 retrotransposons on the human genome. Nat Genet 19: 19-24, 1998.
    • (1998) Nat Genet , vol.19 , pp. 19-24
    • Kazazian Jr., H.H.1    Moran, J.V.2
  • 30
    • 70349482119 scopus 로고    scopus 로고
    • The relationship between the methylenetetrahydrofolate reductase genotypes and the methylation status of the CpG island Loci, LINE-1 and Alu in prostate adenocarcinoma
    • Kim JH, Cho NY, Kim BH, Kim WY, Kim BS, Moon KC, Kang GH. The relationship between the methylenetetrahydrofolate reductase genotypes and the methylation status of the CpG island Loci, LINE-1 and Alu in prostate adenocarcinoma. Kor J Pathol 43: 26-35, 2009.
    • (2009) Kor J Pathol , vol.43 , pp. 26-35
    • Kim, J.H.1    Cho, N.Y.2    Kim, B.H.3    Kim, W.Y.4    Kim, B.S.5    Moon, K.C.6    Kang, G.H.7
  • 31
    • 61349186329 scopus 로고    scopus 로고
    • Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas
    • Kim MJ, White-Cross JA, Shen LL, Issa JPJ, Rashid A. Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas. Mod Pathol 22: 442-449, 2009.
    • (2009) Mod Pathol , vol.22 , pp. 442-449
    • Kim, M.J.1    White-Cross, J.A.2    Shen, L.L.3    Issa, J.P.J.4    Rashid, A.5
  • 32
    • 61349143203 scopus 로고    scopus 로고
    • Prognostic implications of and relationship between CpG island hypermethylation and repetitive DNA hypomethylation in hepatocellular carcinoma
    • Lee HS, Kim BH, Cho NY, Yoo EJ, Choi M, Shin SH, Jang JJ, Suh KS, Kim YS, Kang GH. Prognostic implications of and relationship between CpG island hypermethylation and repetitive DNA hypomethylation in hepatocellular carcinoma. Clin Cancer Res 15: 812-820, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 812-820
    • Lee, H.S.1    Kim, B.H.2    Cho, N.Y.3    Yoo, E.J.4    Choi, M.5    Shin, S.H.6    Jang, J.J.7    Suh, K.S.8    Kim, Y.S.9    Kang, G.H.10
  • 33
    • 0035748130 scopus 로고    scopus 로고
    • The human genome structure and organization
    • Makalowski W. The human genome structure and organization. Acta Biochim Pol 48: 587-598, 2001.
    • (2001) Acta Biochim Pol , vol.48 , pp. 587-598
    • Makalowski, W.1
  • 34
    • 43249128135 scopus 로고    scopus 로고
    • Epigenetic activation of genomic retrotransposon
    • Mansour A. Epigenetic activation of genomic retrotransposon. J Cell Mol Biol 6: 99-107, 2007.
    • (2007) J Cell Mol Biol , vol.6 , pp. 99-107
    • Mansour, A.1
  • 37
    • 34247116336 scopus 로고    scopus 로고
    • Connections between epigenetic gene silencing and human disease
    • Moss TJ, Wallrath LL. Connections between epigenetic gene silencing and human disease. Mutat Res 618: 163-174, 2007.
    • (2007) Mutat Res , vol.618 , pp. 163-174
    • Moss, T.J.1    Wallrath, L.L.2
  • 38
    • 46649094515 scopus 로고    scopus 로고
    • Quantitative PCR analysis for methylation level of genome: Clinical implications in cancer
    • Mutirangura A. Quantitative PCR analysis for methylation level of genome: clinical implications in cancer. Asian Biomed 1: 121-128, 2007.
    • (2007) Asian Biomed , vol.1 , pp. 121-128
    • Mutirangura, A.1
  • 39
    • 43049130760 scopus 로고    scopus 로고
    • LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer
    • DOI 10.1002/ijc.23470
    • Ogino S, Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Kirkner GJ, Fuchs CS. LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Intl J Cancer 122: 2767-2773, 2008. (Pubitemid 351631379)
    • (2008) International Journal of Cancer , vol.122 , Issue.12 , pp. 2767-2773
    • Ogino, S.1    Kawasaki, T.2    Nosho, K.3    Ohnishi, M.4    Suemoto, Y.5    Kirkner, G.J.6    Fuchs, C.S.7
  • 41
    • 84874759504 scopus 로고    scopus 로고
    • Aberrant methylation and associated transcriptional mobilization of Alu elements contributes to genomic instability in hypoxia
    • in press
    • Pal A, Srivastava T, Sharma MK, Mehndiratta M, Das P, Sinha S, Chattopadhyay P. Aberrant methylation and associated transcriptional mobilization of Alu elements contributes to genomic instability in hypoxia. J Cell Mol Med in press.
    • J Cell Mol Med
    • Pal, A.1    Srivastava, T.2    Sharma, M.K.3    Mehndiratta, M.4    Das, P.5    Sinha, S.6    Chattopadhyay, P.7
  • 42
    • 72249101937 scopus 로고    scopus 로고
    • Comparison of CpG island hypermethylation and repetitive DNA hypomethylation in premalignant stages of gastric cancer, stratified for Helicobacter pylori infection
    • Park SY, Yoo EJ, Cho NY, Kim N, Kang GH. Comparison of CpG island hypermethylation and repetitive DNA hypomethylation in premalignant stages of gastric cancer, stratified for Helicobacter pylori infection. J Pathol 219: 410-416 2009.
    • (2009) J Pathol , vol.219 , pp. 410-416
    • Park, S.Y.1    Yoo, E.J.2    Cho, N.Y.3    Kim, N.4    Kang, G.H.5
  • 44
    • 34247151696 scopus 로고    scopus 로고
    • Specific hypermethylation of LINE-1 elements during abnormal overgrowth and differentiation of human placenta
    • Perrin D, Ballestar E, Fraga MF, Frappart L, Esteller M, Guerin JF, Dante R. Specific hypermethylation of LINE-1 elements during abnormal overgrowth and differentiation of human placenta. Oncogene 26: 2518-2524, 2007.
    • (2007) Oncogene , vol.26 , pp. 2518-2524
    • Perrin, D.1    Ballestar, E.2    Fraga, M.F.3    Frappart, L.4    Esteller, M.5    Guerin, J.F.6    Dante, R.7
  • 45
    • 34548432104 scopus 로고    scopus 로고
    • Raising the estimate of functional human sequences
    • Pheasant M, Mattick JS. Raising the estimate of functional human sequences. Genome Res 17: 1245-1253, 2007.
    • (2007) Genome Res , vol.17 , pp. 1245-1253
    • Pheasant, M.1    Mattick, J.S.2
  • 48
    • 0019423126 scopus 로고
    • Effects of the tissue type, age, malignancy and hormonal induction
    • Romanov GA, Vanyushin BF. Effects of the tissue type, age, malignancy and hormonal induction. Biochim Biophys Acta 653: 204-218, 1981.
    • (1981) Biochim Biophys Acta , vol.653 , pp. 204-218
    • Romanov, G.A.1    Vanyushin, B.F.2
  • 49
    • 33645284007 scopus 로고    scopus 로고
    • Methylation of endogenous human retroelements in health and disease
    • Schulz WA, Steinhoff C, Florl AR. Methylation of endogenous human retroelements in health and disease. Curr Top Microbiol Immunol 310: 211-250, 2006.
    • (2006) Curr Top Microbiol Immunol , vol.310 , pp. 211-250
    • Schulz, W.A.1    Steinhoff, C.2    Florl, A.R.3
  • 51
    • 33847789490 scopus 로고    scopus 로고
    • Serum LINE-1 hypomethylation as a potential prognostic marker for hepatocellular carcinoma
    • DOI 10.1016/j.cca.2006.12.029, PII S0009898107000216
    • Tangkijvanich P, Hourpai N, Rattanatanyong P, Wisedopas N, Mahachai V, Mutirangura A. Serum LINE-1 hypomethylation as a potential prognostic marker for hepatocellular carcinoma. Clin Chim Acta 379: 127-133, 2007. (Pubitemid 46389509)
    • (2007) Clinica Chimica Acta , vol.379 , Issue.1-2 , pp. 127-133
    • Tangkijvanich, P.1    Hourpai, N.2    Rattanatanyong, P.3    Wisedopas, N.4    Mahachai, V.5    Mutirangura, A.6
  • 52
    • 34548823021 scopus 로고    scopus 로고
    • Retrotransposons and their role in plant-genome evolution
    • Todorovska E. Retrotransposons and their role in plant-genome evolution. Biotechnol & Biotechnol Eq 21: 294-305, 2007.
    • (2007) Biotechnol & Biotechnol Eq , vol.21 , pp. 294-305
    • Todorovska, E.1
  • 53
    • 0015885681 scopus 로고
    • The 5-methylcytosine in DNA of rats. Tissue and age specificity and the changes induced by hydrocortisone and other agents
    • Vanyushin BF, Nemirovsky LE, Klimenko VV, Vasiliev VK, Belozersky AN. The 5-methylcytosine in DNA of rats. Tissue and age specificity and the changes induced by hydrocortisone and other agents. Gerontologia 19: 138-152, 1973.
    • (1973) Gerontologia , vol.19 , pp. 138-152
    • Vanyushin, B.F.1    Nemirovsky, L.E.2    Klimenko, V.V.3    Vasiliev, V.K.4    Belozersky, A.N.5
  • 56
    • 0020638422 scopus 로고
    • DNA methylation decreases in aging but not in immortal cells
    • Wilson VL, Jones PA. DNA methylation decreases in aging but not in immortal cells. Science 220: 1055-1057, 1983.
    • (1983) Science , vol.220 , pp. 1055-1057
    • Wilson, V.L.1    Jones, P.A.2
  • 57
    • 0023664725 scopus 로고
    • Genomic 5-methyldeoxycytidine decreases with age
    • Wilson VL, Smith RA, Ma S, Cutler RG. Genomic 5-methyldeoxycytidine decreases with age. J Biol Chem 262: 9948-9951, 1987.
    • (1987) J Biol Chem , vol.262 , pp. 9948-9951
    • Wilson, V.L.1    Smith, R.A.2    Ma, S.3    Cutler, R.G.4
  • 58
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 25: 2532-2534, 1997.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 59
    • 2342557977 scopus 로고    scopus 로고
    • A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
    • Yang AS, Estecio MR, Doshi K, Kondo Y, Tajara EH, Issa JP. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 32: e38, 2004.
    • (2004) Nucleic Acids Res , vol.32
    • Yang, A.S.1    Estecio, M.R.2    Doshi, K.3    Kondo, Y.4    Tajara, E.H.5    Issa, J.P.6
  • 60
    • 34047177898 scopus 로고    scopus 로고
    • Molecular phylogenetic analysis of the human endogenous retrovirus e (HERV-E) family in human tissues and human cancers
    • Yi JM, Kim HS. Molecular phylogenetic analysis of the human endogenous retrovirus E (HERV-E) family in human tissues and human cancers. Genes Genet Syst 82: 89-98, 2007.
    • (2007) Genes Genet Syst , vol.82 , pp. 89-98
    • Yi, J.M.1    Kim, H.S.2
  • 61
    • 55249096744 scopus 로고    scopus 로고
    • Phylogenetic analysis of mRNA polyadenylation sites reveals a role of transposable elements in evolution of the 3′-end of genes
    • Youn LJ, Zhe J, Bin T. Phylogenetic analysis of mRNA polyadenylation sites reveals a role of transposable elements in evolution of the 3′-end of genes. Nucleic Acid Res 36: 5581-5590, 2008.
    • (2008) Nucleic Acid Res , vol.36 , pp. 5581-5590
    • Youn, L.J.1    Zhe, J.2    Bin, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.