메뉴 건너뛰기




Volumn 36, Issue 1, 2010, Pages 8-18

Functional role of KLF10 in multiple disease processes

Author keywords

Apoptosis; Bone; Cancer; Differentiation; Estrogen; Heart; Immune system; KLF10; Kr ppel family; Smads; TGF ; TGF inducible early gene; TIEG1

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; EPIDERMAL GROWTH FACTOR; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 10; SMAD2 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 77951140067     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.1002/biof.67     Document Type: Review
Times cited : (99)

References (78)
  • 1
    • 0028971148 scopus 로고
    • Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts
    • Subramaniam, M., Harris, S. A., Oursler, M. J., Rasmussen, K., Riggs, B. L., and Spelsberg, T. C. (1995) Identification of a novel TGF-beta-regulated gene encoding a putative zinc finger protein in human osteoblasts, Nucleic Acids Res., 23, 4907-4912. (Pubitemid 3008385)
    • (1995) Nucleic Acids Research , vol.23 , Issue.23 , pp. 4907-4912
    • Subramaniam, M.1    Harris, S.A.2    Oursler, M.J.3    Rasmussen, K.4    Riggs, B.L.5    Spelsberg, T.C.6
  • 2
    • 0028812689 scopus 로고
    • Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation
    • Blok, L. J., Grossmann, M. E., Perry, J. E., and Tindall, D. J. (1995) Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation, Mol. Endocrinol., 9, 1610-1620.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 1610-1620
    • Blok, L.J.1    Grossmann, M.E.2    Perry, J.E.3    Tindall, D.J.4
  • 3
    • 0032129209 scopus 로고    scopus 로고
    • TGFβ-inducible early gene (TIEG) also codes for early growth response a (EGRα): Evidence of multiple transcripts from alternate promoters
    • DOI 10.1006/geno.1998.5388
    • Fautsch, M. P., Vrabel, A., Subramaniam, M., Hefferen, T. E., Spelsberg, T. C., and Wieben, E. D. (1998) TGFbeta-inducible early gene (TIEG) also codes for early growth response alpha (EGRalpha): evidence of multiple transcripts from alternate promoters, Genomics, 51, 408-416. (Pubitemid 28413207)
    • (1998) Genomics , vol.51 , Issue.3 , pp. 408-416
    • Fautsch, M.P.1    Vrabel, A.2    Subramaniam, M.3    Hefferen, T.E.4    Spelsberg, T.C.5    Wieben, E.D.6
  • 4
    • 0033897176 scopus 로고    scopus 로고
    • A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening
    • Gunther, M., Laithier, M., and Brison, O. (2000) A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening, Mol. Cell Biochem., 210, 131-142.
    • (2000) Mol. Cell Biochem. , vol.210 , pp. 131-142
    • Gunther, M.1    Laithier, M.2    Brison, O.3
  • 5
    • 0031595473 scopus 로고    scopus 로고
    • Characterization of the mouse TGFbeta-inducible early gene (TIEG): Conservation of exon and transcriptional regulatory sequences with evidence of additional transcripts
    • Fautsch, M. P., Vrabel, A., Rickard, D., Subramaniam, M., Spelsberg, T. C., and Wieben, E. D. (1998) Characterization of the mouse TGFbeta-inducible early gene (TIEG): conservation of exon and transcriptional regulatory sequences with evidence of additional transcripts, Mamm. Genome, 9, 838-842.
    • (1998) Mamm. Genome , vol.9 , pp. 838-842
    • Fautsch, M.P.1    Vrabel, A.2    Rickard, D.3    Subramaniam, M.4    Spelsberg, T.C.5    Wieben, E.D.6
  • 6
    • 0032856361 scopus 로고    scopus 로고
    • Three conserved transcriptional repressor domains are a defining feature of the TIEG subfamily of Sp1-like zinc finger proteins
    • Cook, T., Gebelein, B., Belal, M., Mesa, K., and Urrutia, R. (1999) Three conserved transcriptional repressor domains are a defining feature of the TIEG subfamily of Sp1-like zinc finger proteins, J. Biol. Chem., 274, 29500-29504.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29500-29504
    • Cook, T.1    Gebelein, B.2    Belal, M.3    Mesa, K.4    Urrutia, R.5
  • 9
    • 0032189236 scopus 로고    scopus 로고
    • Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line
    • Hofbauer, L. C., Hicok, K. C., and Khosla, S. (1998) Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line, J. Cell. Biochem., 71, 96-108.
    • (1998) J. Cell. Biochem. , vol.71 , pp. 96-108
    • Hofbauer, L.C.1    Hicok, K.C.2    Khosla, S.3
  • 10
    • 46349084348 scopus 로고    scopus 로고
    • Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: An essential role for the activation function 1 domain
    • Hawse, J. R., Subramaniam, M., Monroe, D. G., Hemmingsen, A. H., Ingle, J. N., Khosla, S., Oursler, M. J., and Spelsberg, T. C. (2008) Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: an essential role for the activation function 1 domain, Mol. Endocrinol., 22, 1579-1595.
    • (2008) Mol. Endocrinol. , vol.22 , pp. 1579-1595
    • Hawse, J.R.1    Subramaniam, M.2    Monroe, D.G.3    Hemmingsen, A.H.4    Ingle, J.N.5    Khosla, S.6    Oursler, M.J.7    Spelsberg, T.C.8
  • 11
  • 12
    • 0032475869 scopus 로고    scopus 로고
    • Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth
    • Cook, T., Gebelein, B., Mesa, K., Mladek, A., and Urrutia, R. (1998) Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth, J. Biol. Chem., 273, 25929-25936.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25929-25936
    • Cook, T.1    Gebelein, B.2    Mesa, K.3    Mladek, A.4    Urrutia, R.5
  • 14
    • 0037103863 scopus 로고    scopus 로고
    • Altered expression of novel genes in the cerebral cortex following experimental brain injury
    • Kobori, N., Clifton, G. L., and Dash, P. (2002) Altered expression of novel genes in the cerebral cortex following experimental brain injury, Brain Res. Mol. Brain Res., 104, 148-158.
    • (2002) Brain Res. Mol. Brain Res. , vol.104 , pp. 148-158
    • Kobori, N.1    Clifton, G.L.2    Dash, P.3
  • 15
    • 3042642147 scopus 로고    scopus 로고
    • The zinc finger transcription factor transforming growth factor beta-inducible early gene-1 confers myeloid-specific activation of the leukocyte integrin CD11d promoter
    • Noti, J. D., Johnson, A. K., and Dillon, J. D. (2004) The zinc finger transcription factor transforming growth factor beta-inducible early gene-1 confers myeloid-specific activation of the leukocyte integrin CD11d promoter, J. Biol. Chem., 279, 26948-26958.
    • (2004) J. Biol. Chem. , vol.279 , pp. 26948-26958
    • Noti, J.D.1    Johnson, A.K.2    Dillon, J.D.3
  • 16
    • 13544268327 scopus 로고    scopus 로고
    • The leukocyte integrin gene CD11d is repressed by gut-enriched Kruppel-like factor 4 in myeloid cells
    • Noti, J. D., Johnson, A. K., and Dillon, J. D. (2005) The leukocyte integrin gene CD11d is repressed by gut-enriched Kruppel-like factor 4 in myeloid cells, J. Biol. Chem., 280, 3449-3457.
    • (2005) J. Biol. Chem. , vol.280 , pp. 3449-3457
    • Noti, J.D.1    Johnson, A.K.2    Dillon, J.D.3
  • 17
    • 14244263713 scopus 로고    scopus 로고
    • Gene expression profiling of leiomyoma and myometrial smooth muscle cells in response to transforming growth factor-β
    • DOI 10.1210/en.2004-1377
    • Luo, X., Ding, L., Xu, J., and Chegini, N. (2005) Gene expression profiling of leiomyoma and myometrial smooth muscle cells in response to transforming growth factor-beta, Endocrinology, 146, 1097-1118. (Pubitemid 40289299)
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 1097-1118
    • Luo, X.1    Ding, L.2    Xu, J.3    Chegini, N.4
  • 18
    • 0037683668 scopus 로고    scopus 로고
    • Nitric oxide-mediated upregulation of the TGF-β-inducible early response gene-1 (TIEG1) in human fibroblasts by mRNA stabilization independent of TGF-β
    • DOI 10.1016/S0891-5849(03)00211-9
    • Mitsumoto, M., Mitsumoto, A., and Demple, B. (2003) Nitric oxide-mediated upregulation of the TGF-beta-inducible early response gene-1 (TIEG1) in human fibroblasts by mRNA stabilization independent of TGFbeta, Free Radic. Biol. Med., 34, 1607-1613. (Pubitemid 36638720)
    • (2003) Free Radical Biology and Medicine , vol.34 , Issue.12 , pp. 1607-1613
    • Mitsumoto, M.1    Mitsumoto, A.2    Demple, B.3
  • 19
    • 0030731503 scopus 로고    scopus 로고
    • Cloning and characterization of murine glial cell-derived neurotrophic factor inducible transcription factor (MGIF)
    • Yajima, S., Lammers, C. H., Lee, S. H., Hara, Y., Mizuno, K., and Mouradian, M. M. (1997) Cloning and characterization of murine glial cell-derived neurotrophic factor inducible transcription factor (MGIF), J. Neurosci., 17, 8657-8666. (Pubitemid 27481731)
    • (1997) Journal of Neuroscience , vol.17 , Issue.22 , pp. 8657-8666
    • Yajima, S.1    Lammers, C.-H.2    Lee, S.-H.3    Hara, Y.4    Mizuno, K.5    Mouradian, M.M.6
  • 20
    • 0842291474 scopus 로고    scopus 로고
    • TIEG1 facilitates transforming growth factor-beta-mediated apoptosis in the oligodendroglial cell line OLI-neu
    • Bender, H., Wang, Z., Schuster, N., and Krieglstein, K. (2004) TIEG1 facilitates transforming growth factor-beta-mediated apoptosis in the oligodendroglial cell line OLI-neu, J. Neurosci. Res., 75, 344-352.
    • (2004) J. Neurosci. Res. , vol.75 , pp. 344-352
    • Bender, H.1    Wang, Z.2    Schuster, N.3    Krieglstein, K.4
  • 21
    • 3142702135 scopus 로고    scopus 로고
    • Differential gene expression of TGFβ inducible early gene (TIEG), Smad7, Smad2 and Bard1 in normal and malignant breast tissue
    • DOI 10.1023/B:BREA.0000032926.74216.7d
    • Reinholz, M. M., An, M. W., Johnsen, S. A., Subramaniam, M., Suman, V. J., Ingle, J. N., Roche, P. C., and Spelsberg, T. C. (2004) Differential gene expression of TGF beta inducible early gene (TIEG), Smad7, Smad2 and Bard1 in normal and malignant breast tissue, Breast Cancer Res. Treat., 86, 75-88. (Pubitemid 38918898)
    • (2004) Breast Cancer Research and Treatment , vol.86 , Issue.1 , pp. 75-88
    • Reinholz, M.M.1    An, M.-W.2    Johnsen, S.A.3    Subramaniam, M.4    Suman, V.J.5    Ingle, J.N.6    Roche, P.C.7    Spelsberg, T.C.8
  • 22
    • 0037163044 scopus 로고    scopus 로고
    • Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGF beta-inducible early gene-1 by human seven in absentia homologue
    • Johnsen, S. A., Subramaniam, M., Monroe, D. G., Janknecht, R., and Spelsberg, T. C. (2002) Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGF beta-inducible early gene-1 by human seven in absentia homologue, J. Biol. Chem., 277, 30754-30759.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30754-30759
    • Johnsen, S.A.1    Subramaniam, M.2    Monroe, D.G.3    Janknecht, R.4    Spelsberg, T.C.5
  • 23
    • 2442685276 scopus 로고    scopus 로고
    • Dual functions of transcription factors, transforming growth factor-β-inducible early gene (TIEG)2 and Sp3, are mediated by CACCC element and Sp1 sites of human monoamine oxidase (MAO) B Gene
    • DOI 10.1074/jbc.M312638200
    • Ou, X. M., Chen, K., and Shih, J. C. (2004) Dual functions of transcription factors, transforming growth factor-beta-inducible early gene (TIEG)2 and Sp3, are mediated by CACCC element and Sp1 sites of human monoamine oxidase (MAO) B gene, J. Biol. Chem., 279, 21021-21028. (Pubitemid 38656503)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.20 , pp. 21021-21028
    • Ou, X.-M.1    Chen, K.2    Shih, J.C.3
  • 25
    • 34548606496 scopus 로고    scopus 로고
    • TIEG1 induces apoptosis through mitochondrial apoptotic pathway and promotes apoptosis induced by homoharringtonine and velcade
    • DOI 10.1016/j.febslet.2007.07.008, PII S0014579307007569
    • Jin, W., Di, G., Li, J., Chen, Y., Li, W., Wu, J., Cheng, T., Yao, M., and Shao, Z. (2007) TIEG1 induces apoptosis through mitochondrial apoptotic pathway and promotes apoptosis induced by homoharringtonine and velcade, FEBS Lett., 581, 3826-3832. (Pubitemid 47411513)
    • (2007) FEBS Letters , vol.581 , Issue.20 , pp. 3826-3832
    • Jin, W.1    Di, G.2    Li, J.3    Chen, Y.4    Li, W.5    Wu, J.6    Cheng, T.7    Yao, M.8    Shao, Z.9
  • 26
    • 0034003075 scopus 로고    scopus 로고
    • TIEG proteins join the Smads as TGF-β-regulated transcription factors that control pancreatic cell growth
    • Cook, T. and Urrutia, R. (2000) TIEG proteins join the Smads as TGFbeta- regulated transcription factors that control pancreatic cell growth, Am. J. Physiol. Gastrointest. Liver Physiol., 278, G513-521. (Pubitemid 30213116)
    • (2000) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.278 , Issue.4
    • Cook, T.1    Urrutia, R.2
  • 27
    • 0032696730 scopus 로고    scopus 로고
    • The transforming growth factor beta(1)-inducible transcription factor TIEG1, mediates apoptosis through oxidative stress
    • Ribeiro, A., Bronk, S. F., Roberts, P. J., Urrutia, R., and Gores, G. J. (1999) The transforming growth factor beta(1)-inducible transcription factor TIEG1, mediates apoptosis through oxidative stress, Hepatology, 30, 1490-1497.
    • (1999) Hepatology , vol.30 , pp. 1490-1497
    • Ribeiro, A.1    Bronk, S.F.2    Roberts, P.J.3    Urrutia, R.4    Gores, G.J.5
  • 28
    • 0347419437 scopus 로고    scopus 로고
    • Gene structure and evolution of Tieg3, a new member of the Tieg family of proteins
    • Wang, Z., Peters, B., Klussmann, S., Bender, H., Herb, A., and Krieglstein, K. (2004) Gene structure and evolution of Tieg3, a new member of the Tieg family of proteins, Gene, 325, 25-34.
    • (2004) Gene , vol.325 , pp. 25-34
    • Wang, Z.1    Peters, B.2    Klussmann, S.3    Bender, H.4    Herb, A.5    Krieglstein, K.6
  • 29
    • 0034954161 scopus 로고    scopus 로고
    • A conserved α-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A
    • DOI 10.1128/MCB.21.15.5041-5049.2001
    • Zhang, J. S., Moncrieffe, M. C., Kaczynski, J., Ellenrieder, V., Prendergast, F. G., and Urrutia, R. (2001) A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A, Mol. Cell. Biol., 21, 5041-5049. (Pubitemid 32656401)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.15 , pp. 5041-5049
    • Zhang, J.-S.1    Moncrieffe, M.C.2    Kaczynski, J.3    Ellenrieder, V.4    Prendergast, F.G.5    Urrutia, R.6
  • 30
    • 0037093448 scopus 로고    scopus 로고
    • Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor
    • Ellenrieder, V., Zhang, J. S., Kaczynski, J., and Urrutia, R. (2002) Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor, EMBO J., 21, 2451-2460.
    • (2002) EMBO J. , vol.21 , pp. 2451-2460
    • Ellenrieder, V.1    Zhang, J.S.2    Kaczynski, J.3    Urrutia, R.4
  • 32
    • 0031796493 scopus 로고    scopus 로고
    • Estrogen regulation of a transforming growth factor-β inducible early gene that inhibits deoxyribonucleic acid synthesis in human osteoblasts
    • DOI 10.1210/en.139.3.1346
    • Tau, K. R., Hefferan, T. E., Waters, K. M., Robinson, J. A., Subramaniam, M., Riggs, B. L., and Spelsberg, T. C. (1998) Estrogen regulation of a transforming growth factor-beta inducible early gene that inhibits deoxyribonucleic acid synthesis in human osteoblasts, Endocrinology, 139, 1346-1353. (Pubitemid 28510156)
    • (1998) Endocrinology , vol.139 , Issue.3 , pp. 1346-1353
    • Tau, K.R.1    Hefferan, T.E.2    Waters, K.M.3    Robinson, J.A.4    Subramaniam, M.5    Riggs, B.L.6    Spelsberg, T.C.7
  • 33
    • 0037158512 scopus 로고    scopus 로고
    • TGFβ inducible early gene enhances TGFβ/Smad-dependent transcriptional responses
    • DOI 10.1038/sj.onc.1205681
    • Johnsen, S. A., Subramaniam, M., Janknecht, R., and Spelsberg, T. C. (2002) TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses, Oncogene, 21, 5783-5790. (Pubitemid 35333012)
    • (2002) Oncogene , vol.21 , Issue.37 , pp. 5783-5790
    • Johnsen, S.A.1    Subramaniam, M.2    Janknecht, R.3    Spelsberg, T.C.4
  • 34
    • 0036384562 scopus 로고    scopus 로고
    • Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene
    • Johnsen, S. A., Subramaniam, M., Katagiri, T., Janknecht, R., and Spelsberg, T. C. (2002) Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene, J. Cell Biochem., 87, 233-241.
    • (2002) J. Cell Biochem. , vol.87 , pp. 233-241
    • Johnsen, S.A.1    Subramaniam, M.2    Katagiri, T.3    Janknecht, R.4    Spelsberg, T.C.5
  • 36
    • 0345035482 scopus 로고    scopus 로고
    • A zinc-finger transcription factor induced by TGF-β promotes apoptotic cell death in epithelial Mv1Lu cells
    • DOI 10.1016/S0014-5793(99)01051-0, PII S0014579399010510
    • Chalaux, E., Lopez-Rovira, T., Rosa, J. L., Pons, G., Boxer, L. M., Bartrons, R., and Ventura, F. (1999) A zinc-finger transcription factor induced by TGF-beta promotes apoptotic cell death in epithelial Mv1Lu cells, FEBS Lett., 457, 478-482. (Pubitemid 29414747)
    • (1999) FEBS Letters , vol.457 , Issue.3 , pp. 478-482
    • Chalaux, E.1    Lopez-Rovira, T.2    Rosa, J.L.3    Pons, G.4    Boxer, L.M.5    Bartrons, R.6    Ventura, F.7
  • 37
    • 20144365151 scopus 로고    scopus 로고
    • Smad signal and TGFβ induced apoptosis in human lymphoma cells
    • DOI 10.1016/j.cyto.2005.01.013, PII S1043466605000463
    • Sebestyen, A., Barna, G., Nagy, K., Janosi, J., Paku, S., Kohut, E., Berczi, L., Mihalik, R., and Kopper, L. (2005) Smad signal and TGFbeta induced apoptosis in human lymphoma cells, Cytokine, 30, 228-235. (Pubitemid 40775840)
    • (2005) Cytokine , vol.30 , Issue.5 , pp. 228-235
    • Sebestyen, A.1    Barna, G.2    Nagy, K.3    Janosi, J.4    Paku, S.5    Kohut, E.6    Berczi, L.7    Mihalik, R.8    Kopper, L.9
  • 38
    • 1542344367 scopus 로고    scopus 로고
    • Identification of genes responsive to apoptosis in HL-60 cells
    • Jin, W., Qu, L. F., Min, P., Chen, S., Li, H., Lu, H., and Hou, Y. T. (2004) Identification of genes responsive to apoptosis in HL-60 cells, Acta Pharmacol. Sin., 25, 319-326.
    • (2004) Acta Pharmacol. Sin. , vol.25 , pp. 319-326
    • Jin, W.1    Qu, L.F.2    Min, P.3    Chen, S.4    Li, H.5    Lu, H.6    Hou, Y.T.7
  • 39
    • 33144473049 scopus 로고    scopus 로고
    • Transforming growth factor-beta and bone morphogenetic proteins: Cooperative players in chick and murine programmed retinal cell death
    • Franke, A. G., Gubbe, C., Beier, M., and Duenker, N. (2006) Transforming growth factor-beta and bone morphogenetic proteins: cooperative players in chick and murine programmed retinal cell death, J. Comp. Neurol., 495, 263-278.
    • (2006) J. Comp. Neurol. , vol.495 , pp. 263-278
    • Franke, A.G.1    Gubbe, C.2    Beier, M.3    Duenker, N.4
  • 40
    • 4444298193 scopus 로고    scopus 로고
    • The TGFβ inducible early gene plays a central role in the anti-proliferative response to TGFβ
    • DOI 10.1002/sita.200400032
    • Johnsen, S. A., Subramaniam, M., Effenberger, K. E., and Spelsberg, T. C. (2004) The TGF-beta inducible early gene plays a central role in the anti-proliferative response to TGF-beta, Signal Transduct., 4, 29-35. (Pubitemid 39163048)
    • (2004) Signal Transduction , vol.4 , Issue.1-2 , pp. 29-35
    • Johnsen, S.A.1    Subramaniam, M.2    Effenberger, K.E.3    Spelsberg, T.C.4
  • 45
    • 76449122151 scopus 로고    scopus 로고
    • TIEG1-null osteocytes display defects in their morphology, density and surrounding bone matrix
    • DOI: 1080/10255840903081164
    • Haddad, O., Hawse, J. R., Subramaniam, M., Spelsberg, T. C., Bensamoun, S. F., TIEG1-null osteocytes display defects in their morphology, density and surrounding bone matrix, J. Musculoskelet. Res., DOI: 1080/10255840903081164.
    • J. Musculoskelet. Res.
    • Haddad, O.1    Hawse, J.R.2    Subramaniam, M.3    Spelsberg, T.C.4    Bensamoun, S.F.5
  • 49
    • 26844468478 scopus 로고    scopus 로고
    • Targeted disruption of Smad4 in cardiomyocytes results in cardiac hypertrophy and heart failure
    • Wang, J., Xu, N., Feng, X., Hou, N., Zhang, J., Cheng, X., Chen, Y., Zhang, Y., and Yang, X. (2005) Targeted disruption of Smad4 in cardiomyocytes results in cardiac hypertrophy and heart failure, Circ. Res., 97, 821-828.
    • (2005) Circ. Res. , vol.97 , pp. 821-828
    • Wang, J.1    Xu, N.2    Feng, X.3    Hou, N.4    Zhang, J.5    Cheng, X.6    Chen, Y.7    Zhang, Y.8    Yang, X.9
  • 51
    • 39449083806 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1
    • Venuprasad, K., Huang, H., Harada, Y., Elly, C., Subramaniam, M., Spelsberg, T., Su, J., and Liu, Y. C. (2008) The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1, Nat. Immunol., 9, 245-253.
    • (2008) Nat. Immunol. , vol.9 , pp. 245-253
    • Venuprasad, K.1    Huang, H.2    Harada, Y.3    Elly, C.4    Subramaniam, M.5    Spelsberg, T.6    Su, J.7    Liu, Y.C.8
  • 52
    • 0032100588 scopus 로고    scopus 로고
    • Expression of early growth response genes in human prostate cancer
    • Eid, M. A., Kumar, M. V., Iczkowski, K. A., Bostwick, D. G., and Tindall, D. J. (1998) Expression of early growth response genes in human prostate cancer, Cancer Res., 58, 2461-2468. (Pubitemid 28252710)
    • (1998) Cancer Research , vol.58 , Issue.11 , pp. 2461-2468
    • Eid, M.A.1    Kumar, M.V.2    Iczkowski, K.A.3    Bostwick, D.G.4    Tindall, D.J.5
  • 53
    • 0034866971 scopus 로고    scopus 로고
    • TGFβ-mediated signaling and transcriptional regulation in pancreatic development and cancer
    • DOI 10.1097/00001574-200109000-00006
    • Ellenrieder, V., Fernandez-Zapico, M. E., Urrutia, R. (2001) TGF-beta mediated signaling and transcriptional regulation in pancreatic development and cancer, Curr. Opin. Gastroenterol., 17, 434-440. (Pubitemid 32783733)
    • (2001) Current Opinion in Gastroenterology , vol.17 , Issue.5 , pp. 434-440
    • Ellenrieder, V.1    Fernandez Zapico, M.E.2    Urrutia, R.3
  • 54
    • 45949086682 scopus 로고    scopus 로고
    • TGFbeta regulated gene expression by Smads and Sp1/KLF-like transcription factors in cancer
    • Ellenrieder, V. (2008) TGFbeta regulated gene expression by Smads and Sp1/KLF-like transcription factors in cancer, Anticancer Res., 28, 1531-1539.
    • (2008) Anticancer Res. , vol.28 , pp. 1531-1539
    • Ellenrieder, V.1
  • 56
    • 0028950494 scopus 로고
    • TGF-beta regulation of nuclear proto-oncogenes and TGF-beta gene expression in normal human osteoblast-like cells
    • Subramaniam, M., Oursler, M. J., Rasmussen, K., Riggs, B. L., and Spelsberg, T. C. (1995) TGF-beta regulation of nuclear proto-oncogenes and TGF-beta gene expression in normal human osteoblast-like cells, J. Cell. Biochem., 57, 52-61.
    • (1995) J. Cell. Biochem. , vol.57 , pp. 52-61
    • Subramaniam, M.1    Oursler, M.J.2    Rasmussen, K.3    Riggs, B.L.4    Spelsberg, T.C.5
  • 58
    • 57849134562 scopus 로고    scopus 로고
    • MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer
    • Hu, G., Chong, R. A., Yang, Q., Wei, Y., Blanco, M. A., Li, F., Reiss, M., Au, J. L., Haffty, B. G., and Kang, Y. (2009) MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer, Cancer Cell, 15, 9-20.
    • (2009) Cancer Cell , vol.15 , pp. 9-20
    • Hu, G.1    Chong, R.A.2    Yang, Q.3    Wei, Y.4    Blanco, M.A.5    Li, F.6    Reiss, M.7    Au, J.L.8    Haffty, B.G.9    Kang, Y.10
  • 59
    • 57749084479 scopus 로고    scopus 로고
    • Down-regulation of stathmin is required for TGF-beta inducible early gene 1 induced growth inhibition of pancreatic cancer cells
    • Jiang, L., Chen, Y., Chan, C. Y., Wang, X., Lin, L., He, M. L., Lin, M. C., Yew, D. T., Sung, J. J., Li, J. C., and Kung, H. F. (2009) Down-regulation of stathmin is required for TGF-beta inducible early gene 1 induced growth inhibition of pancreatic cancer cells, Cancer Lett., 274, 101-108.
    • (2009) Cancer Lett. , vol.274 , pp. 101-108
    • Jiang, L.1    Chen, Y.2    Chan, C.Y.3    Wang, X.4    Lin, L.5    He, M.L.6    Lin, M.C.7    Yew, D.T.8    Sung, J.J.9    Li, J.C.10    Kung, H.F.11
  • 60
    • 0038792746 scopus 로고    scopus 로고
    • Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction
    • Partin, J. V., Anglin, I. E., and Kyprianou, N. (2003) Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction, Br. J. Cancer, 88, 1615-1621.
    • (2003) Br. J. Cancer , vol.88 , pp. 1615-1621
    • Partin, J.V.1    Anglin, I.E.2    Kyprianou, N.3
  • 61
    • 47549109957 scopus 로고    scopus 로고
    • Differential effects of diabetes induced by streptozotocin and that develops spontaneously on prostate growth in Bio Breeding (BB) rats
    • Yono, M., Mane, S. M., Lin, A., Weiss, R. M., and Latifpour, J. (2008) Differential effects of diabetes induced by streptozotocin and that develops spontaneously on prostate growth in Bio Breeding (BB) rats, Life Sci., 83, 192-197.
    • (2008) Life Sci. , vol.83 , pp. 192-197
    • Yono, M.1    Mane, S.M.2    Lin, A.3    Weiss, R.M.4    Latifpour, J.5
  • 62
    • 0037179546 scopus 로고    scopus 로고
    • Absence of mutations in the transforming growth factor-beta inducible early gene 1, TIEG1, in pancreatic cancer
    • Antonello, D., Moore, P. S., Zamboni, G., Falconi, M., and Scarpa, A. (2002) Absence of mutations in the transforming growth factor-beta inducible early gene 1, TIEG1, in pancreatic cancer, Cancer Lett., 183, 179-183.
    • (2002) Cancer Lett. , vol.183 , pp. 179-183
    • Antonello, D.1    Moore, P.S.2    Zamboni, G.3    Falconi, M.4    Scarpa, A.5
  • 63
    • 0242363581 scopus 로고    scopus 로고
    • 15-hydroxy-eicosatetraenoic acid arrests growth of colorectal cancer cells via a peroxisome proliferator-activated receptor gamma-dependent pathway
    • Chen, G. G., Xu, H., Lee, J. F., Subramaniam, M., Leung, K. L., Wang, S. H., Chan, U. P., and Spelsberg, T. C. (2003) 15-hydroxy-eicosatetraenoic acid arrests growth of colorectal cancer cells via a peroxisome proliferator- activated receptor gamma-dependent pathway, Int. J. Cancer, 107, 837-843.
    • (2003) Int. J. Cancer , vol.107 , pp. 837-843
    • Chen, G.G.1    Xu, H.2    Lee, J.F.3    Subramaniam, M.4    Leung, K.L.5    Wang, S.H.6    Chan, U.P.7    Spelsberg, T.C.8
  • 64
    • 0036875351 scopus 로고    scopus 로고
    • TGFβ1 kills lymphoma cells using mitochondrial apoptotic pathway with the help of caspase-8
    • Barna, G., Sebestyen, A., Chinopoulos, C. C., Nagy, K., Mihalik, R., Paku, S., and Kopper, L. (2002) TGF beta 1 kills lymphoma cells using mitochondrial apoptotic pathway with the help of caspase-8, Anticancer Res., 22, 3867-3872. (Pubitemid 36134407)
    • (2002) Anticancer Research , vol.22 , Issue.6 C , pp. 3867-3872
    • Barna, G.1    Sebestyen, A.2    Chinopoulos, C.C.3    Nagy, K.4    Mihalik, R.5    Paku, S.6    Kopper, L.7
  • 65
    • 15744378043 scopus 로고    scopus 로고
    • EGR1 predicts PTEN and survival in patients with non-small-cell lung cancer
    • Ferraro, B., Bepler, G., Sharma, S., Cantor, A., and Haura, E. B. (2005) EGR1 predicts PTEN and survival in patients with non-small-cell lung cancer, J. Clin. Oncol., 23, 1921-1926.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 1921-1926
    • Ferraro, B.1    Bepler, G.2    Sharma, S.3    Cantor, A.4    Haura, E.B.5
  • 66
    • 43049113104 scopus 로고    scopus 로고
    • Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors
    • Ivanov, S. V., Ivanova, A. V., Salnikow, K., Timofeeva, O., Subramaniam, M., and Lerman, M. I. (2008) Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors, Biochem. Biophys. Res. Commun., 370, 536-540.
    • (2008) Biochem. Biophys. Res. Commun. , vol.370 , pp. 536-540
    • Ivanov, S.V.1    Ivanova, A.V.2    Salnikow, K.3    Timofeeva, O.4    Subramaniam, M.5    Lerman, M.I.6
  • 68
    • 16644366016 scopus 로고    scopus 로고
    • Cell and tissue specific expression of human Kruppel-like transcription factors in human ocular surface
    • Chiambaretta, F., De Graeve, F., Turet, G., Marceau, G., Gain, P., Dastugue, B., Rigal, D., and Sapin, V. (2004) Cell and tissue specific expression of human Kruppel-like transcription factors in human ocular surface, Mol. Vis., 10, 901-909.
    • (2004) Mol. Vis. , vol.10 , pp. 901-909
    • Chiambaretta, F.1    De Graeve, F.2    Turet, G.3    Marceau, G.4    Gain, P.5    Dastugue, B.6    Rigal, D.7    Sapin, V.8
  • 70
    • 36849007594 scopus 로고    scopus 로고
    • Chronic fluoxetine treatment induces brain region-specific upregulation of genes associated with BDNF-induced long-term potentiation
    • Alme, M. N., Wibrand, K., Dagestad, G., and Bramham, C. R. (2007) Chronic fluoxetine treatment induces brain region-specific upregulation of genes associated with BDNF-induced long-term potentiation, Neural. Plast., 26496.
    • (2007) Neural. Plast. , pp. 26496
    • Alme, M.N.1    Wibrand, K.2    Dagestad, G.3    Bramham, C.R.4
  • 73
    • 37549020350 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc
    • Alvarez-Rodriguez, R., Barzi, M., Berenguer, J., and Pons, S. (2007) Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc, J. Biol. Chem., 282, 37170-37180.
    • (2007) J. Biol. Chem. , vol.282 , pp. 37170-37180
    • Alvarez-Rodriguez, R.1    Barzi, M.2    Berenguer, J.3    Pons, S.4
  • 74
    • 45149117519 scopus 로고    scopus 로고
    • Tieg3/Klf11 induces apoptosis in OLI-neu cells and enhances the TGFβ-signaling pathway by transcriptional repression of Smad7
    • DOI 10.1002/jcb.21669
    • Gohla, G., Krieglstein, K., and Spittau, B. (2008) Tieg3/Klf11 induces apoptosis in OLI-neu cells and enhances the TGF-beta signaling pathway by transcriptional repression of Smad7, J. Cell Biochem., 104, 850-861. (Pubitemid 351830835)
    • (2008) Journal of Cellular Biochemistry , vol.104 , Issue.3 , pp. 850-861
    • Gohla, G.1    Krieglstein, K.2    Spittau, B.3
  • 75
    • 20444399088 scopus 로고    scopus 로고
    • Modulation of the TGFbeta/Smad signaling pathway in mesangial cells by CTGF/CCN2
    • Wahab, N. A., Weston, B. S., and Mason, R. M. (2005) Modulation of the TGFbeta/Smad signaling pathway in mesangial cells by CTGF/CCN2, Exp. Cell Res., 307, 305-314.
    • (2005) Exp. Cell Res. , vol.307 , pp. 305-314
    • Wahab, N.A.1    Weston, B.S.2    Mason, R.M.3
  • 77
    • 4544364176 scopus 로고    scopus 로고
    • Expression profiling of insulin action in human myotubes: Induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes
    • DOI 10.1016/j.bbrc.2004.08.146, PII S0006291X04019199
    • Hansen, L., Gaster, M., Oakeley, E. J., Brusgaard, K., Damsgaard Nielsen, E. M., Beck-Nielsen, H., Pedersen, O., and Hemmings, B. A. (2004) Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes, Biochem. Biophys. Res. Commun., 323, 685-695. (Pubitemid 39221150)
    • (2004) Biochemical and Biophysical Research Communications , vol.323 , Issue.2 , pp. 685-695
    • Hansen, L.1    Gaster, M.2    Oakeley, E.J.3    Brusgaard, K.4    Damsgaard Nielsen, E.-M.5    Beck-Nielsen, H.6    Pedersen, O.7    Hemmings, B.A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.