메뉴 건너뛰기




Volumn 35, Issue 6, 2010, Pages 1363-1373

Differential Regulation of Behavioral Tolerance to WIN55,212-2 by GASP1

Author keywords

CB1 receptor; Downregulation; GASP; Tolerance; Trafficking; WIN55,212 2

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR ASSOCIATED SORTING PROTEIN1; UNCLASSIFIED DRUG;

EID: 77951116102     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2010.6     Document Type: Article
Times cited : (38)

References (47)
  • 1
    • 67549144921 scopus 로고    scopus 로고
    • Blood, adipose tissue and brain levels of the cannabinoid ligands WIN-55,212 and SR-141716A after their intraperitoneal injection in mice: Compound-specific and area-specific distribution within the brain
    • Barna I, Till I, Haller J (2009). Blood, adipose tissue and brain levels of the cannabinoid ligands WIN-55,212 and SR-141716A after their intraperitoneal injection in mice: compound-specific and area-specific distribution within the brain. Eur Neuropsy-chopharmacol 19: 533-541.
    • (2009) Eur Neuropsy-chopharmacol , vol.19 , pp. 533-541
    • Barna, I.1    Till, I.2    Haller, J.3
  • 3
    • 0034255129 scopus 로고    scopus 로고
    • Time course for the induction and maintenance of tolerance to Delta(9)-tetrahydrocannabinol in mice
    • Bass CE, Martin BR (2000). Time course for the induction and maintenance of tolerance to Delta(9)-tetrahydrocannabinol in mice. Drug Alcohol Depend 60: 113-119.
    • (2000) Drug Alcohol Depend , vol.60 , pp. 113-119
    • Bass, C.E.1    Martin, B.R.2
  • 4
    • 69549110080 scopus 로고    scopus 로고
    • Attenuated behavioural responses to acute and chronic cocaine in GASP-1-deficient mice
    • Boeuf J, Trigo JM, Moreau PH, Lecourtier L, Vogel E, Cassel JC et al. (2009). Attenuated behavioural responses to acute and chronic cocaine in GASP-1-deficient mice. Eur J Neurosci 30: 860-868.
    • (2009) Eur J Neurosci , vol.30 , pp. 860-868
    • Boeuf, J.1    Trigo, J.M.2    Moreau, P.H.3    Lecourtier, L.4    Vogel, E.5    Cassel, J.C.6
  • 5
    • 0019843126 scopus 로고
    • Hypothalamic mechanisms in thermoregula-tion
    • Boulant JA (1981). Hypothalamic mechanisms in thermoregula-tion. Fed Proc 40: 2843-2850.
    • (1981) Fed Proc , vol.40 , pp. 2843-2850
    • Boulant, J.A.1
  • 6
    • 0030988864 scopus 로고    scopus 로고
    • Regional differences in cannabinoid receptor/G-protein coupling in rat brain
    • Breivogel CS, Sim LJ, Childers SR (1997). Regional differences in cannabinoid receptor/G-protein coupling in rat brain. J Phar-macol Exp Ther 282: 1632-1642.
    • (1997) J Phar-macol Exp Ther , vol.282 , pp. 1632-1642
    • Breivogel, C.S.1    Sim, L.J.2    Childers, S.R.3
  • 7
    • 1242272173 scopus 로고    scopus 로고
    • Behavioral effects of cannabinoids show differential sensitivity to cannabinoid receptor blockade and tolerance development
    • De Vry J, Jentzsch KR, Kuhl E, Eckel G (2004). Behavioral effects of cannabinoids show differential sensitivity to cannabinoid receptor blockade and tolerance development. Behav Pharmacol 15: 1-12.
    • (2004) Behav Pharmacol , vol.15 , pp. 1-12
    • De Vry, J.1    Jentzsch, K.R.2    Kuhl, E.3    Eckel, G.4
  • 8
    • 0022509199 scopus 로고
    • Cannabinoid pharmacology
    • Dewey WL (1986). Cannabinoid pharmacology. Pharmacol Rev 38: 151-178.
    • (1986) Pharmacol Rev , vol.38 , pp. 151-178
    • Dewey, W.L.1
  • 9
    • 33846428788 scopus 로고    scopus 로고
    • Kinins promote B2 receptor endocytosis and delay constitutive B1 receptor endocytosis
    • Enquist J, Skroder C, Whistler JL, Leeb-Lundberg LM (2007). Kinins promote B2 receptor endocytosis and delay constitutive B1 receptor endocytosis. Mol Pharmacol 71: 494-507.
    • (2007) Mol Pharmacol , vol.71 , pp. 494-507
    • Enquist, J.1    Skroder, C.2    Whistler, J.L.3    Leeb-Lundberg, L.M.4
  • 10
    • 0343724969 scopus 로고    scopus 로고
    • Cannabinoid receptor down-regulation without alteration of the inhibitory effect of CP 55 940 on adenylyl cyclase in the cerebellum of CP 55940-tolerant mice
    • Fan F, Tao Q, Abood M, Martin BR (1996). Cannabinoid receptor down-regulation without alteration of the inhibitory effect of CP 55 940 on adenylyl cyclase in the cerebellum of CP 55940-tolerant mice. Brain Res 706: 13-20.
    • (1996) Brain Res , vol.706 , pp. 13-20
    • Fan, F.1    Tao, Q.2    Abood, M.3    Martin, B.R.4
  • 11
    • 20444388640 scopus 로고    scopus 로고
    • Cannabinoid tolerance and dependence: A review of studies in laboratory animals
    • Gonzalez S, Cebeira M, Fernandez-Ruiz J (2005). Cannabinoid tolerance and dependence: a review of studies in laboratory animals. Pharmacol Biochem Behav 81: 300-318.
    • (2005) Pharmacol Biochem Behav , vol.81 , pp. 300-318
    • Gonzalez, S.1    Cebeira, M.2    Fernandez-Ruiz, J.3
  • 12
    • 0031863268 scopus 로고    scopus 로고
    • Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes
    • Griffin G, Atkinson PJ, Showalter VM, Martin BR, Abood ME (1998). Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes. J Pharmacol Exp Ther 285: 553-560.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 553-560
    • Griffin, G.1    Atkinson, P.J.2    Showalter, V.M.3    Martin, B.R.4    Abood, M.E.5
  • 13
    • 41149090339 scopus 로고    scopus 로고
    • Regulation of GPCRs by endocytic membrane trafficking and its potential implications
    • Hanyaloglu AC, von Zastrow M (2008). Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu Rev Pharmacol Toxicol 48: 537-568.
    • (2008) Annu Rev Pharmacol Toxicol , vol.48 , pp. 537-568
    • Hanyaloglu, A.C.1    Von Zastrow, M.2
  • 14
    • 0025954862 scopus 로고
    • Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradio-graphic study
    • Herkenham M, Lynn AB, Johnson MR, Melvin LS, de Costa BR, Rice KC (1991). Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradio-graphic study. J Neurosci 11: 563-583.
    • (1991) J Neurosci , vol.11 , pp. 563-583
    • Herkenham, M.1    Lynn, A.B.2    Johnson, M.R.3    Melvin, L.S.4    De Costa, B.R.5    Rice, K.C.6
  • 15
    • 11144229682 scopus 로고    scopus 로고
    • A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP)
    • Heydorn A, Sondergaard BP, Ersboll B, Holst B, Nielsen FC, Haft CR et al. (2004). A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP). J Biol Chem 279: 54291-54303.
    • (2004) J Biol Chem , vol.279 , pp. 54291-54303
    • Heydorn, A.1    Sondergaard, B.P.2    Ersboll, B.3    Holst, B.4    Nielsen, F.C.5    Haft, C.R.6
  • 16
    • 0032484245 scopus 로고    scopus 로고
    • Cannabinoid modula-tion of wide dynamic range neurons in the lumbar dorsal horn of the rat by spinally administered WIN55,212-2
    • Hohmann AG, Tsou K, Walker JM (1998). Cannabinoid modula-tion of wide dynamic range neurons in the lumbar dorsal horn of the rat by spinally administered WIN55,212-2. Neurosci Lett 257: 119-122.
    • (1998) Neurosci Lett , vol.257 , pp. 119-122
    • Hohmann, A.G.1    Tsou, K.2    Walker, J.M.3
  • 17
    • 0032771955 scopus 로고    scopus 로고
    • Internalization and recycling of the CB1 cannabinoid receptor
    • Hsieh C, Brown S, Derleth C, Mackie K (1999). Internalization and recycling of the CB1 cannabinoid receptor. J Neurochem 73: 493-501.
    • (1999) J Neurochem , vol.73 , pp. 493-501
    • Hsieh, C.1    Brown, S.2    Derleth, C.3    MacKie, K.4
  • 18
    • 0038692066 scopus 로고    scopus 로고
    • Cannabis and the brain
    • Iversen L (2003). Cannabis and the brain. Brain 126(Pt 6): 1252-1270.
    • (2003) Brain , vol.126 , Issue.PART 6 , pp. 1252-1270
    • Iversen, L.1
  • 19
    • 43549093276 scopus 로고    scopus 로고
    • Modulation by female sex hormones of the cannabinoid-induced catalepsy and analgesia in ovariectomized mice
    • Kalbasi Anaraki D, Sianati S, Sadeghi M, Ghasemi M, Javadi P, Ejtemaei Mehr S et al. (2008). Modulation by female sex hormones of the cannabinoid-induced catalepsy and analgesia in ovariectomized mice. Eur J Pharmacol 586: 189-196.
    • (2008) Eur J Pharmacol , vol.586 , pp. 189-196
    • Kalbasi Anaraki, D.1    Sianati, S.2    Sadeghi, M.3    Ghasemi, M.4    Javadi, P.5    Ejtemaei Mehr, S.6
  • 21
    • 0036669501 scopus 로고    scopus 로고
    • Study of cannabinoid dependence in animals
    • Maldonado R (2002). Study of cannabinoid dependence in animals. Pharmacol Ther 95: 153-164.
    • (2002) Pharmacol Ther , vol.95 , pp. 153-164
    • Maldonado, R.1
  • 22
    • 33745492803 scopus 로고    scopus 로고
    • Neuromodulatory functions of the endocannabinoid system
    • Marsicano G, Lutz B (2006). Neuromodulatory functions of the endocannabinoid system. J Endocrinol Invest 29(3 Suppl): 27-46.
    • (2006) J Endocrinol Invest , vol.29 , Issue.3 SUPPL. , pp. 27-46
    • Marsicano, G.1    Lutz, B.2
  • 23
    • 2542442555 scopus 로고    scopus 로고
    • Signaling pathways involved in the development of cannabinoid tolerance
    • Martin BR, Sim-Selley LJ, Selley DE (2004). Signaling pathways involved in the development of cannabinoid tolerance. Trends Pharmacol Sci 25: 325-330.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 325-330
    • Martin, B.R.1    Sim-Selley, L.J.2    Selley, D.E.3
  • 24
    • 33847403181 scopus 로고    scopus 로고
    • Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-asso-ciated sorting protein GASP1
    • Martini L, Waldhoer M, Pusch M, Kharazia V, Fong J, Lee JH et al. (2007). Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-asso-ciated sorting protein GASP1. FASEB J 21: 802-811.
    • (2007) FASEB J , vol.21 , pp. 802-811
    • Martini, L.1    Waldhoer, M.2    Pusch, M.3    Kharazia, V.4    Fong, J.5    Lee, J.H.6
  • 25
    • 35649000942 scopus 로고    scopus 로고
    • Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice
    • Monory K, Blaudzun H, Massa F, Kaiser N, Lemberger T, Schutz G et al. (2007). Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice. PLoS Biol 5: e269.
    • (2007) PLoS Biol , vol.5
    • Monory, K.1    Blaudzun, H.2    Massa, F.3    Kaiser, N.4    Lemberger, T.5    Schutz, G.6
  • 26
    • 0027196816 scopus 로고
    • Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: A quantitative autoradiographic study
    • Oviedo A, Glowa J, Herkenham M (1993). Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: a quantitative autoradiographic study. Brain Res 616: 293-302.
    • (1993) Brain Res , vol.616 , pp. 293-302
    • Oviedo, A.1    Glowa, J.2    Herkenham, M.3
  • 27
    • 0035037811 scopus 로고    scopus 로고
    • Cannabinoid CB(1) receptor agonists produce cerebellar dysfunction in mice
    • Patel S, Hillard CJ (2001). Cannabinoid CB(1) receptor agonists produce cerebellar dysfunction in mice. J Pharmacol Exp Ther 297: 629-637.
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 629-637
    • Patel, S.1    Hillard, C.J.2
  • 28
    • 65449146377 scopus 로고    scopus 로고
    • Emerging strategies for exploiting cannabinoid receptor agonists as medicines
    • Pertwee RG (2009). Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br J Pharmacol 156: 397-411.
    • (2009) Br J Pharmacol , vol.156 , pp. 397-411
    • Pertwee, R.G.1
  • 29
    • 0036015112 scopus 로고    scopus 로고
    • CB1 receptors in the preoptic anterior hypothalamus regulate WIN 55212-2 [(4,5-dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-car-bonyl) -6H-pyrrolo[3,2,1ij]quinolin-6-one]-induced hypother-mia
    • Rawls SM, Cabassa J, Geller EB, Adler MW (2002). CB1 receptors in the preoptic anterior hypothalamus regulate WIN 55212-2 [(4,5-dihydro-2-methyl-4(4- morpholinylmethyl)-1-(1-naphthalenyl-car-bonyl)-6H-pyrrolo[3,2,1ij] quinolin-6-one]-induced hypother-mia. J Pharmacol Exp Ther 301: 963-968.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 963-968
    • Rawls, S.M.1    Cabassa, J.2    Geller, E.B.3    Adler, M.W.4
  • 30
    • 0029912522 scopus 로고    scopus 로고
    • Characterization and distribution of binding sites for [3H]-SR 141716A, a selective brain (CB1) cannabinoid receptor antagonist, in rodent brain
    • Rinaldi-Carmona M, Pialot F, Congy C, Redon E, Barth F, Bachy A et al. (1996). Characterization and distribution of binding sites for [3H]-SR 141716A, a selective brain (CB1) cannabinoid receptor antagonist, in rodent brain. Life Sci 58: 1239-1247.
    • (1996) Life Sci , vol.58 , pp. 1239-1247
    • Rinaldi-Carmona, M.1    Pialot, F.2    Congy, C.3    Redon, E.4    Barth, F.5    Bachy, A.6
  • 32
    • 0033020235 scopus 로고    scopus 로고
    • 35S] GTPγS binding and cannabinoid receptor mRNA levels in several brain structures of adult male rats chronically exposed to R-methanandamide
    • DOI 10.1016/S0197-0186(99)00020-0, PII S0197018699000200
    • Romero J, Berrendero F, Garcia-Gil L, Lin SY, Makriyannis A, Ramos JA et al. (1999). Cannabinoid receptor and WIN-55,212-2-stimulated [35S]GTPgammaS binding and cannabinoid receptor mRNA levels in several brain structures of adult male rats chronically exposed to R-methanandamide. Neurochem Int 34: 473-482. (Pubitemid 29243889)
    • (1999) Neurochemistry International , vol.34 , Issue.6 , pp. 473-482
    • Romero, J.1    Berrendero, F.2    Garcia-Gil, L.3    Lin, S.Y.4    Makriyannis, A.5    Ramos, J.A.6    Fernandez-Ruiz, J.J.7
  • 33
    • 0030959336 scopus 로고    scopus 로고
    • Effects of chronic exposure to delta-tetrahydrocannabinol on cannabinoid receptor binding and mRNA levels in several rat brain regions
    • Romero J, Garcia-Palomero E, Castro JG, Garcia-Gil L, Ramos JA, Fernandez-Ruiz JJ (1997). Effects of chronic exposure to delta- tetrahydrocannabinol on cannabinoid receptor binding and mRNA levels in several rat brain regions. Brain Res Mol Brain Res 46: 100-108.
    • (1997) Brain Res Mol Brain Res , vol.46 , pp. 100-108
    • Romero, J.1    Garcia-Palomero, E.2    Castro, J.G.3    Garcia-Gil, L.4    Ramos, J.A.5    Fernandez-Ruiz, J.J.6
  • 34
    • 18844399321 scopus 로고    scopus 로고
    • Ras/ERK signalling in cannabinoid tolerance: From behaviour to cellular aspects
    • Rubino T, Forlani G, Vigano D, Zippel R, Parolaro D (2005). Ras/ERK signalling in cannabinoid tolerance: from behaviour to cellular aspects. J Neurochem 93: 984-991.
    • (2005) J Neurochem , vol.93 , pp. 984-991
    • Rubino, T.1    Forlani, G.2    Vigano, D.3    Zippel, R.4    Parolaro, D.5
  • 35
    • 0742271034 scopus 로고    scopus 로고
    • Regulation of cannabinoid CB1 receptors in the central nervous system by chronic cannabinoids
    • Sim-Selley LJ (2003). Regulation of cannabinoid CB1 receptors in the central nervous system by chronic cannabinoids. Crit Rev Neurobiol 15: 91-119.
    • (2003) Crit Rev Neurobiol , vol.15 , pp. 91-119
    • Sim-Selley, L.J.1
  • 36
    • 0036784515 scopus 로고    scopus 로고
    • Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3- [(morpholinyl)methyl]pyrrolo [1,2,3-de]-1,4-b enzoxazinyl]-(1-naphthalenyl) methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabi-noid receptor adaptation in mice
    • Sim-Selley LJ, Martin BR (2002). Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo [1,2,3-de]-1,4-b enzoxazinyl]-(1-naphthalenyl)methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabi-noid receptor adaptation in mice. J Pharmacol Exp Ther 303: 36-44.
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 36-44
    • Sim-Selley, L.J.1    Martin, B.R.2
  • 37
    • 33747626926 scopus 로고    scopus 로고
    • Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid adminis-tration
    • Sim-Selley LJ, Schechter NS, Rorrer WK, Dalton GD, Hernandez J, Martin BR et al. (2006). Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid adminis-tration. Mol Pharmacol 70: 986-996.
    • (2006) Mol Pharmacol , vol.70 , pp. 986-996
    • Sim-Selley, L.J.1    Schechter, N.S.2    Rorrer, W.K.3    Dalton, G.D.4    Hernandez, J.5    Martin, B.R.6
  • 38
    • 0029829841 scopus 로고    scopus 로고
    • Effects of chronic treatment with delta9-tetrahydrocannabinol on canna-binoid-stimulated [35S]GTPgammaS autoradiography in rat brain
    • Sim LJ, Hampson RE, Deadwyler SA, Childers SR (1996). Effects of chronic treatment with delta9-tetrahydrocannabinol on canna-binoid-stimulated [35S]GTPgammaS autoradiography in rat brain. J Neurosci 16: 8057-8066.
    • (1996) J Neurosci , vol.16 , pp. 8057-8066
    • Sim, L.J.1    Hampson, R.E.2    Deadwyler, S.A.3    Childers, S.R.4
  • 39
    • 2042524353 scopus 로고    scopus 로고
    • Identification of a novel family of G protein-coupled receptor associated sorting proteins
    • Simonin F, Karcher P, Boeuf JJ, Matifas A, Kieffer BL (2004). Identification of a novel family of G protein-coupled receptor associated sorting proteins. J Neurochem 89: 766-775.
    • (2004) J Neurochem , vol.89 , pp. 766-775
    • Simonin, F.1    Karcher, P.2    Boeuf, J.J.3    Matifas, A.4    Kieffer, B.L.5
  • 40
    • 0032545995 scopus 로고    scopus 로고
    • A role of nitric oxide in WIN 55,212-2 tolerance in mice
    • Spina E, Trovati A, Parolaro D, Giagnoni G (1998). A role of nitric oxide in WIN 55,212-2 tolerance in mice. Eur J Pharmacol 343: 157-163.
    • (1998) Eur J Pharmacol , vol.343 , pp. 157-163
    • Spina, E.1    Trovati, A.2    Parolaro, D.3    Giagnoni, G.4
  • 41
    • 0037184952 scopus 로고    scopus 로고
    • Ubiquitination-independent trafficking of G protein-coupled receptors to lysosomes
    • Tanowitz M, Von Zastrow M (2002). Ubiquitination-independent trafficking of G protein-coupled receptors to lysosomes. J Biol Chem 277: 50219-50222.
    • (2002) J Biol Chem , vol.277 , pp. 50219-50222
    • Tanowitz, M.1    Von Zastrow, M.2
  • 43
    • 35748974181 scopus 로고    scopus 로고
    • Changes in G protein-coupled receptor sorting protein affinity regulate postendocytic targeting of G protein-coupled receptors
    • Thompson D, Pusch M, Whistler JL (2007). Changes in G protein-coupled receptor sorting protein affinity regulate postendocytic targeting of G protein-coupled receptors. J Biol Chem 282: 29178-29185.
    • (2007) J Biol Chem , vol.282 , pp. 29178-29185
    • Thompson, D.1    Pusch, M.2    Whistler, J.L.3
  • 44
    • 67349104825 scopus 로고    scopus 로고
    • PKCepsilon regulates behavioral sensitivity, binding and tolerance to the CB1 receptor agonist WIN55,212-2
    • Wallace MJ, Newton PM, McMahon T, Connolly J, Huibers A, Whistler J et al. (2009). PKCepsilon regulates behavioral sensitivity, binding and tolerance to the CB1 receptor agonist WIN55,212-2. Neuropsychopharmacology 34: 1733-1742.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1733-1742
    • Wallace, M.J.1    Newton, P.M.2    McMahon, T.3    Connolly, J.4    Huibers, A.5    Whistler, J.6
  • 46
    • 27744570711 scopus 로고    scopus 로고
    • Mammalian BEX, WEX and GASP genes: Coding and non-coding chimaerism sustained by gene conversion events
    • Winter EE, Ponting CP (2005). Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. BMC Evol Biol 5: 54.
    • (2005) BMC Evol Biol , vol.5 , pp. 54
    • Winter, E.E.1    Ponting, C.P.2
  • 47
    • 38449115036 scopus 로고    scopus 로고
    • Role of receptor internalization in the agonist-induced desensitization of cannabinoid type 1 receptors
    • Wu DF, Yang LQ, Goschke A, Stumm R, Brandenburg LO, Liang YJ et al. (2008). Role of receptor internalization in the agonist-induced desensitization of cannabinoid type 1 receptors. J Neurochem 104: 1132-1143.
    • (2008) J Neurochem , vol.104 , pp. 1132-1143
    • Wu, D.F.1    Yang, L.Q.2    Goschke, A.3    Stumm, R.4    Brandenburg, L.O.5    Liang, Y.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.