Characterization and distribution of binding sites for [3H]-SR 141716A, a selective brain (CB1) cannabinoid receptor antagonist, in rodent brain

Life Sciences

Volumn 58, Issue 15, 1996, Pages 1239-1247

  Rinaldi Carmona, Murielle ^a   Pialot, Françoise ^a   Congy, Christian ^a   Redon, Elsa ^a   Barth, Francis ^a   Bachy, André ^a   Brelière, Jean Claude ^a   Soubrié, Philippe ^a   Le Fur, Gérard ^a  

^a SANOFI   (France)

Author keywords

Brain; cAMP; Cannabinoid receptor; cGMP; Receptor antagonist; SR 141716A

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 2 METHYLSEROTONIN; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ANANDAMIDE; ATROPINE; BUTACLAMOL; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; CIMETIDINE; DRONABINOL; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); HALOPERIDOL; IDAZOXAN; KETANSERIN; MEPYRAMINE; NALOXONE; PRAZOSIN; PROPRANOLOL; RADIOLIGAND; RIMONABANT; SPIPERONE; VERAPAMIL; VERATRIDINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; BRAIN MEMBRANE; BRAIN REGION; BRAIN SYNAPTOSOME; CONCENTRATION RESPONSE; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; RECEPTOR OCCUPANCY; TISSUE DISTRIBUTION;

EID: 0029912522     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/0024-3205(96)00085-9     Document Type: Article

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