In utero exposure of female CD-1 mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue

Cardiovascular Toxicology

Volumn 10, Issue 1, 2010, Pages 37-50

  Torres, Salina M ^a,b   March, Thomas H ^b   Carter, Meghan M ^b   McCash, Consuelo L ^b   Seilkop, Steven K ^c   Poirier, Miriam C ^d   Walker, Dale M ^e   Walker, Vernon E ^a,b,e,f  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^c SKS Consulting Services   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e BioMosaics Incorporated   (United States)

^f UNIVERSITY OF VERMONT   (United States)

Author keywords

3TC; AZT; Cardiotoxicity; Electron microscopy; Histopathology; Mitochondrial pathology; PTAH stain; Transplacental exposure; Trichrome stain; Ultrastructural pathology

Indexed keywords

LAMIVUDINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DISEASE SEVERITY; ELECTRON MICROSCOPY; FEMALE; GESTATIONAL AGE; HEART INJURY; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART WEIGHT; HISTOPATHOLOGY; MALE; MITOCHONDRIAL TOXICITY; MOUSE; NONHUMAN; PLACENTAL TRANSFER; PRENATAL EXPOSURE; PRIORITY JOURNAL; PUERPERIUM; STAINING; TOXICITY TESTING;

ANIMALS; ANTI-HIV AGENTS; DNA, MITOCHONDRIAL; DRUG INTERACTIONS; ECHOCARDIOGRAPHY; FEMALE; FETUS; HEART; LAMIVUDINE; MALE; MATERNAL-FETAL EXCHANGE; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA, HEART; MUTATION; MYOCARDIUM; ORGAN SIZE; OXIDATIVE PHOSPHORYLATION; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; REVERSE TRANSCRIPTASE INHIBITORS; SEX CHARACTERISTICS; ZIDOVUDINE;

ANIMALIA; MUS;

EID: 77951114341     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12012-010-9061-3     Document Type: Article

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