Greater resistance to inflammation at adulthood could contribute to extended life span of p66Shc-/- mice

Experimental Gerontology

Volumn 45, Issue 5, 2010, Pages 343-350

  Berry, Alessandra ^a,c   Carnevale, Daniela ^a,d   Giorgio, Marco ^b   Pelicci, Pier Giuseppe ^b   de Kloet, Edo Ronald ^c   Alleva, Enrico ^a   Minghetti, Luisa ^a   Cirulli, Francesca ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c LEIDEN UNIVERSITY   (Netherlands)

^d IRCCS NEUROMED   (Italy)

Author keywords

Aging; Brain derived neurotrophic factor (BDNF); Hypothalamic pituitary adrenal (HPA) axis; Inflammation; Isoprostanes (15 F2t IsoP); Lipopolysaccharide (LPS); Oxidative stress (OS); Transgenic mice

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BRAIN DERIVED NEUROTROPHIC FACTOR; GLUCOCORTICOID; ISOPROSTANE DERIVATIVE; PROSTAGLANDIN E2; PROTEIN P66;

ADULTHOOD; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; CONTROLLED STUDY; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFLAMMATION; LIFE EXTENSION; MALE; MOUSE; MUTANT; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; DEXAMETHASONE; DINOPROST; DINOPROSTONE; INFLAMMATION; LIPOPOLYSACCHARIDES; LONGEVITY; MALE; MICE; MICE, KNOCKOUT; OXIDATIVE STRESS; SHC SIGNALING ADAPTOR PROTEINS;

BACTERIA (MICROORGANISMS); MUS; MUS MUSCULUS;

EID: 77951093530     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2010.01.010     Document Type: Article

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