Naked plasmid DNA formulation: Effect of different disaccharides on stability after lyophilisation

AAPS PharmSciTech

Volumn 11, Issue 1, 2010, Pages 344-350

  Quaak, Susanne G L ^a   Haanen, John B A G ^b   Beijnen, Jos H ^a,c   Nuijen, Bastiaan ^a  

^a SLOTERVAART HOSPITAL   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Disaccharides; Formulation; Lyophilisation; Naked pDNA; Stability

Indexed keywords

DISACCHARIDE; LACTOSE; LUCIFERASE; MALTOSE; PLASMID DNA; SUCROSE; TREHALOSE;

AREA UNDER THE CURVE; ARTICLE; DNA SUPERCOILING; DRUG FORMULATION; DRUG PURITY; DRUG STABILITY; DRUG STORAGE; FREEZE DRYING; GLASS TRANSITION TEMPERATURE; HUMAN; HUMAN EXPERIMENT; MOISTURE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STORAGE TEMPERATURE; WATER CONTENT;

CHEMISTRY, PHARMACEUTICAL; DISACCHARIDES; DNA; DOSAGE FORMS; EXCIPIENTS; FREEZE DRYING; HUMANS; HUMIDITY; LACTOSE; MALTOSE; PLASMIDS; SUCROSE; TRANSFECTION; TREHALOSE; WATER;

EID: 77950918447     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-010-9391-2     Document Type: Article

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