Incorporation of Lipophilic Drugs in Sugar Glasses by Lyophilization using a Mixture of Water and Tertiary Butyl Alcohol as Solvent

Journal of Pharmaceutical Sciences

Volumn 93, Issue 3, 2004, Pages 713-725

  Van Drooge, D J ^a   Hinrichs, W L J ^a   Frijlink, H W ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Amorphous; Crystallization; Cyclosporine A; Freeze drying; Inulin; Physical stability; Residual TBA; Solid dispersion; Solubility; 9 tetrahydrocannabinol (THC)

Indexed keywords

CYCLOSPORIN A; DIAZEPAM; DRONABINOL; DRUG CARRIER; INULIN; NIFEDIPINE; SOLVENT; SUCROSE; SUGAR; TERT BUTYL ALCOHOL; TREHALOSE; WATER;

ANALYTIC METHOD; ARTICLE; CRYSTALLIZATION; DISPERSION; DRUG MIXTURE; DRUG STABILITY; FREEZE DRYING; GLASS TRANSITION TEMPERATURE; LIPOPHILICITY; LYOPHILISATE; MEASUREMENT; PHYSICAL CHEMISTRY;

EID: 1442334238     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10590     Document Type: Article

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