Upregulation of AKT1 protein expression in forskolin-stimulated macrophage: Evidence from ChIP analysis that CREB binds to and activates the AKT1 promoter

Journal of Cellular Biochemistry

Volumn 100, Issue 4, 2007, Pages 1022-1033

  Misra, Uma Kant ^a   Pizzo, Salvatore Vincent ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

CREB and Akt promoter activation; Silencing of CREB gene expression by RNAi and Akt1 regulation; Synthesis of radiolabeled Akt1; Transcriptional upregulation of Akt synthesis

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DOUBLE STRANDED RNA; FORSKOLIN; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROTEIN AKT1; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL CELL; ARTICLE; CELL STIMULATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SYNTHESIS; GENE ACTIVATION; GENE EXPRESSION; GENE SILENCING; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RNA INTERFERENCE; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

ANIMALS; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLOHEXIMIDE; DACTINOMYCIN; FORSKOLIN; GENE EXPRESSION REGULATION; ISOQUINOLINES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; RNA, MESSENGER; SULFONAMIDES; UP-REGULATION;

EID: 33847008691     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21086     Document Type: Article

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