Apolipoprotein E and mimetic peptide initiate a calcium-dependent signaling response in macrophages

Journal of Leukocyte Biology

Volumn 70, Issue 4, 2001, Pages 677-683

  Misra, U K ^a   Adlakha, C L ^a   Gawdi, G ^a   McMillian, M K ^a   Pizzo, S V ^a   Laskowitz, D T ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apolipoprotein E; Lipoprotein receptor related protein; Macrophage; Receptor associated protein; Signal transduction

Indexed keywords

APOLIPOPROTEIN E; CALCIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; NICKEL; PEPTIDE; PERTUSSIS TOXIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; MACROPHAGE; MOUSE; NONHUMAN; PEPTIDE ANALYSIS; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN INTERACTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANIMALS; APOLIPOPROTEINS E; BINDING, COMPETITIVE; CALCIUM SIGNALING; CELLS, CULTURED; INOSITOL 1,4,5-TRISPHOSPHATE; KINETICS; LDL-RECEPTOR RELATED PROTEIN 1; MACROPHAGES; MICE; NICKEL; PEPTIDES; PERTUSSIS TOXIN; RECEPTORS, IMMUNOLOGIC; VIRULENCE FACTORS, BORDETELLA;

EID: 0034787587     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Apoprotein E suppresses phytohemagglutinin-activated phospholipid turnover in peripheral blood mononuclear cells
2. Immunoregulatory plasma low density lipoprotein: The biologic activity and receptor-binding specificity is independent of neutral lipids
3. Immunoregulatory plasma lipoproteins: Role of apoprotein E and apoprotein B
4. Apolipoprotein E is a biologically active constituent of the normal immunoregulatory lipoprotein, LDL-In
5. Apolipoprotein E-deficient mice have impaired innate immune responses to Listeria monocytogenes in vivo
6. Apolipoprotein E knock-out mice are highly susceptible to endotoxemia and Klebsiella pneumoniae infection
7. Altered immune responses in apolipoprotein E-deficient mice
8. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
9. ApoE genotype and survival from intracerebral haemorrhage
10. Association of apolipoprotein E polymorphism with outcome after head injury
11. Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia
12. Human apolipoprotein E3 in aqueous solution. I. Evidence for two structural domains
13. The receptor-binding domain of human apolipoprotein E: Monoclonal antibody inhibition of binding
14. The receptor-binding domain of human apolipoprotein E: Binding of apolipoprotein E fragments
15. Complete protein sequence and identification of structural domains of human apolipoprotein B
16. The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein
17. Apolipoprotein E and atherosclerosis
18. 2-macroglobulin receptor in Alzheimer and control postmortem human brain
19. 2M signaling receptor
20. 2-macroglobulin signaling receptor
21. 2M signaling receptor
22. 2-macroglobulin receptor on murine peritoneal macrophages mediates the binding and catabolism of low density lipoprotein
23. Lactoferrin specifically inhibits endocytosis of chylomicron remnants but not α-macroglobulin
24. 2-macroglobulin-recognition site
25. Lactoferrin binding to heparan sulfate proteoglycans and the LDL receptor-related protein: Further evidence supporting the importance of direct binding of remnant lipoproteins to HSPG
26. Rapid accumulation of inositol triphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol
27. Capacitative calcium entry
28. Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor
29. Nickel is a specific inhibitor for the binding of activated alpha 2-macroglobulin to the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor
30. Apolipoprotein E suppresses glial cell secretion of TNF alpha
31. Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production
32. Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E
33. Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth
34. Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line
35. Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro
36. Rapid elevation of neuronal cytoplasmic calcium by apolipoprotein E peptide
37. Low-density-lipoprotein-receptor-related protein (LRP) interacts with a GTP-binding protein