메뉴 건너뛰기




Volumn 71, Issue 2, 2002, Pages 359-366

Activation of the RON receptor tyrosine kinase protects murine macrophages from apoptotic death induced by bacterial lipopolysaccharide

Author keywords

Apoptosis; iNOS; MSP; PI 3 kinase

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P53; PROTEIN P85; PROTEIN RON; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

EID: 0036486765     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (24)

References (46)
  • 1
    • 84937092509 scopus 로고
    • Wound healing: The role of the macrophage and other immune cells
    • DiPietro, L. A. (1995) Wound healing: the role of the macrophage and other immune cells. Shock 4, 233-240.
    • (1995) Shock , vol.4 , pp. 233-240
    • DiPietro, L.A.1
  • 2
    • 0028987883 scopus 로고
    • Macrophages and inflammatory mediators in tissue injury
    • Laskin, D. L., Pendino, K. J. (1995) Macrophages and inflammatory mediators in tissue injury. Annu. Rev. Pharmacol. Toxicol. 35, 655-677.
    • (1995) Annu. Rev. Pharmacol. Toxicol. , vol.35 , pp. 655-677
    • Laskin, D.L.1    Pendino, K.J.2
  • 3
    • 0026081695 scopus 로고
    • Mechanisms and modulation of macrophage activation
    • Nathan, C. (1991) Mechanisms and modulation of macrophage activation. Behring Inst. Mitt. 88, 200-207.
    • (1991) Behring Inst. Mitt. , vol.88 , pp. 200-207
    • Nathan, C.1
  • 4
    • 0032999383 scopus 로고    scopus 로고
    • Structure-function relationships of bacterial endotoxins. Contribution to microbial sepsis
    • Morrison, D. C., Silverstein, R., Luchi, M., Shnyra, A. (1999) Structure-function relationships of bacterial endotoxins. Contribution to microbial sepsis. Infect. Dis. Clin. North Am. 13, 313-340.
    • (1999) Infect. Dis. Clin. North Am. , vol.13 , pp. 313-340
    • Morrison, D.C.1    Silverstein, R.2    Luchi, M.3    Shnyra, A.4
  • 7
    • 0029522992 scopus 로고
    • Lipopolysaccharide binding protein participation in cellular activation by LPS
    • Su, G. L., Simmons, R. L., Wang, S. C. (1995) Lipopolysaccharide binding protein participation in cellular activation by LPS. Crit. Rev. Immunol. 15, 201-214.
    • (1995) Crit. Rev. Immunol. , vol.15 , pp. 201-214
    • Su, G.L.1    Simmons, R.L.2    Wang, S.C.3
  • 8
    • 0031193939 scopus 로고    scopus 로고
    • Inducible macrophage apoptosis following sepsis is mediated by cysteine protease activation and nitric oxide release
    • Williams, T. E., Ayala, A., Chaudry, I. H. (1997) Inducible macrophage apoptosis following sepsis is mediated by cysteine protease activation and nitric oxide release. J. Surg. Res. 70, 113-118.
    • (1997) J. Surg. Res. , vol.70 , pp. 113-118
    • Williams, T.E.1    Ayala, A.2    Chaudry, I.H.3
  • 9
    • 0033166302 scopus 로고    scopus 로고
    • Interferon γ induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis
    • Xaus, J., Cardo, M., Valledor, A. F., Soler, C., Lloberas, J., Celada, A. (1999) Interferon γ induces the expression of p21waf-1 and arrests macrophage cell cycle, preventing induction of apoptosis. Immunity 11, 103-113.
    • (1999) Immunity , vol.11 , pp. 103-113
    • Xaus, J.1    Cardo, M.2    Valledor, A.F.3    Soler, C.4    Lloberas, J.5    Celada, A.6
  • 10
    • 0027318311 scopus 로고
    • A novel putative receptor protein tyrosine kinase of the met family
    • Ronsin, C., Muscatelli, F., Mattei, M. G., Breathnach, R. (1993) A novel putative receptor protein tyrosine kinase of the met family. Oncogene 8, 1195-1202.
    • (1993) Oncogene , vol.8 , pp. 1195-1202
    • Ronsin, C.1    Muscatelli, F.2    Mattei, M.G.3    Breathnach, R.4
  • 11
    • 0028206124 scopus 로고
    • Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells
    • Iwama, A., Okano, K., Sudo, T., Matsuda, Y., Suda, T. (1994) Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells. Blood 83, 3160-3169.
    • (1994) Blood , vol.83 , pp. 3160-3169
    • Iwama, A.1    Okano, K.2    Sudo, T.3    Matsuda, Y.4    Suda, T.5
  • 12
    • 0029027666 scopus 로고
    • The murine stk gene product, a transmembrane protein tyrosine kinase, is a receptor for macrophage-stimulating protein
    • Wang, M. H., Iwama, A., Skeel, A., Suda, T., Leonard, E. J. (1995) The murine stk gene product, a transmembrane protein tyrosine kinase, is a receptor for macrophage-stimulating protein. Proc. Natl. Acad. Sci. USA 92, 3933-3937.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3933-3937
    • Wang, M.H.1    Iwama, A.2    Skeel, A.3    Suda, T.4    Leonard, E.J.5
  • 13
    • 0028139182 scopus 로고
    • Identification of the ron gene product as the receptor for the human macrophage stimulating protein
    • Wang, M. H., Ronsin, C., Gesnel, M. C., Coupey, L., Skeel, A., Leonard, E. J., Breathnach, R. (1994) Identification of the ron gene product as the receptor for the human macrophage stimulating protein. Science 266, 117-119.
    • (1994) Science , vol.266 , pp. 117-119
    • Wang, M.H.1    Ronsin, C.2    Gesnel, M.C.3    Coupey, L.4    Skeel, A.5    Leonard, E.J.6    Breathnach, R.7
  • 15
    • 0025938869 scopus 로고
    • Characterization of the DNF15S2 locus on human chromosome 3: Identification of a gene coding for four kringle domains with homology to hepatocyte growth factor
    • Han, S., Stuart, L. A., Degen, S. J. (1991) Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor. Biochemistry 30, 9768-9780.
    • (1991) Biochemistry , vol.30 , pp. 9768-9780
    • Han, S.1    Stuart, L.A.2    Degen, S.J.3
  • 16
    • 0025756806 scopus 로고
    • Macrophage stimulating protein: Purification, partial amino acid sequence, and cellular activity
    • Skeel, A., Yoshimura, T., Showalter, S. D., Tanaka, S., Appella, E., Leonard, E. J. (1991) Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity. J. Exp. Med. 173, 1227-1234.
    • (1991) J. Exp. Med. , vol.173 , pp. 1227-1234
    • Skeel, A.1    Yoshimura, T.2    Showalter, S.D.3    Tanaka, S.4    Appella, E.5    Leonard, E.J.6
  • 17
    • 0028874987 scopus 로고
    • Terminal differentiation of murine resident peritoneal macrophages is characterized by expression of the STK protein tyrosine kinase, a receptor for macrophage-stimulating protein
    • Iwama, A., Wang, M-H., Yamaguchi, N., Ohno, N., Okano, K., Sudo, T., Takeya, M., Gervais, F., Morissette, C., Leonard, E. J., Suda, T. (1995) Terminal differentiation of murine resident peritoneal macrophages is characterized by expression of the STK protein tyrosine kinase, a receptor for macrophage-stimulating protein. Blood 86, 3394-3403.
    • (1995) Blood , vol.86 , pp. 3394-3403
    • Iwama, A.1    Wang, M.-H.2    Yamaguchi, N.3    Ohno, N.4    Okano, K.5    Sudo, T.6    Takeya, M.7    Gervais, F.8    Morissette, C.9    Leonard, E.J.10    Suda, T.11
  • 18
    • 0029933168 scopus 로고    scopus 로고
    • Macrophage-stimulating protein activates STK receptor tyrosine kinase on osteoclasts and facilitates bone resorption by osteoclast-like cells
    • Kurihara, N., Iwama, A., Tatsumi, J., Ikeda, K., Suda, T. (1996) Macrophage-stimulating protein activates STK receptor tyrosine kinase on osteoclasts and facilitates bone resorption by osteoclast-like cells. Blood 87, 3704-3710.
    • (1996) Blood , vol.87 , pp. 3704-3710
    • Kurihara, N.1    Iwama, A.2    Tatsumi, J.3    Ikeda, K.4    Suda, T.5
  • 19
    • 0031683197 scopus 로고    scopus 로고
    • Proteolytic cleavage and activation of pro-macrophage-stimulating protein and upregulation of its receptor in tissue injury
    • Nanney, L. B., Skeel, A., Luan, J., Polis, S., Richmond, A., Wang, M-H., Leonard, E. J. (1998) Proteolytic cleavage and activation of pro-macrophage-stimulating protein and upregulation of its receptor in tissue injury. J. Investig. Dermatol. 111, 573-581.
    • (1998) J. Investig. Dermatol. , vol.111 , pp. 573-581
    • Nanney, L.B.1    Skeel, A.2    Luan, J.3    Polis, S.4    Richmond, A.5    Wang, M.-H.6    Leonard, E.J.7
  • 20
    • 0031061689 scopus 로고    scopus 로고
    • Deregulated inflammatory response in mice lacking the STK/RON receptor tyrosine kinase
    • Correll, P. H., Iwama, A., Tondat, S., Mayrhofer, G., Suda, T., Bernstein, A. (1997) Deregulated inflammatory response in mice lacking the STK/RON receptor tyrosine kinase. Genes Funct. 1, 69-83.
    • (1997) Genes Funct. , vol.1 , pp. 69-83
    • Correll, P.H.1    Iwama, A.2    Tondat, S.3    Mayrhofer, G.4    Suda, T.5    Bernstein, A.6
  • 22
    • 0029959639 scopus 로고    scopus 로고
    • STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family
    • Iwama, A., Yamaguchi, N., Suda, T. (1996) STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family. EMBO J. 15, 5866-5875.
    • (1996) EMBO J. , vol.15 , pp. 5866-5875
    • Iwama, A.1    Yamaguchi, N.2    Suda, T.3
  • 23
    • 0028352123 scopus 로고
    • Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin- or cytokine-stimulated mouse macrophages
    • Wang, M-H., Cox, G. W., Yoshimura, T., Sheffler, L. A., Skeel, A., Leonard, E. J. (1994) Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin- or cytokine-stimulated mouse macrophages. J. Biol. Chem. 269, 14027-14031.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14027-14031
    • Wang, M.-H.1    Cox, G.W.2    Yoshimura, T.3    Sheffler, L.A.4    Skeel, A.5    Leonard, E.J.6
  • 24
    • 0038698924 scopus 로고    scopus 로고
    • Nitric oxide (NO): An effector of apoptosis
    • Brune, B., Knethen, A., Sandau, K. B. (1999) Nitric oxide (NO): an effector of apoptosis. Cell Death Differ. 6, 969-975.
    • (1999) Cell Death Differ. , vol.6 , pp. 969-975
    • Brune, B.1    Knethen, A.2    Sandau, K.B.3
  • 25
    • 0032211131 scopus 로고    scopus 로고
    • Activation of the RON receptor tyrosine kinase inhibits inducible nitric oxide synthase (iNOS) expression by murine peritoneal exudate macrophages: Phosphatidylinositol-3 kinase is required for RON-mediated inhibition of iNOS expression
    • Chen, Y-Q., Fisher, J. H., Wang, M-H. (1998) Activation of the RON receptor tyrosine kinase inhibits inducible nitric oxide synthase (iNOS) expression by murine peritoneal exudate macrophages: phosphatidylinositol-3 kinase is required for RON-mediated inhibition of iNOS expression. J. Immunol. 161, 4950-4959.
    • (1998) J. Immunol. , vol.161 , pp. 4950-4959
    • Chen, Y.-Q.1    Fisher, J.H.2    Wang, M.-H.3
  • 26
    • 0033920907 scopus 로고    scopus 로고
    • Lipopolysaccharide (LPS)-induced death of C3H mouse peritoneal macrophages in the presence of cycloheximide: Different susceptibilities of C3H/HEN and C3H/HeJ mice macrophages
    • Karahashi, H., Amano, F. (2000) Lipopolysaccharide (LPS)-induced death of C3H mouse peritoneal macrophages in the presence of cycloheximide: different susceptibilities of C3H/HEN and C3H/HeJ mice macrophages. J. Endotoxin Res. 6, 33-39.
    • (2000) J. Endotoxin Res. , vol.6 , pp. 33-39
    • Karahashi, H.1    Amano, F.2
  • 27
    • 0344431242 scopus 로고    scopus 로고
    • U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activation
    • Brockhaus, F., Brune, B. (1998) U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activation. Exp. Cell Res. 238, 33-41.
    • (1998) Exp. Cell Res. , vol.238 , pp. 33-41
    • Brockhaus, F.1    Brune, B.2
  • 28
    • 0032514371 scopus 로고    scopus 로고
    • Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor
    • Santoro, M. M., Penengo, L., Minetto, M., Orecchia, S., Cilli, M., Gaudino, G. (1998) Point mutations in the tyrosine kinase domain release the oncogenic and metastatic potential of the Ron receptor. Oncogene 17, 741-749.
    • (1998) Oncogene , vol.17 , pp. 741-749
    • Santoro, M.M.1    Penengo, L.2    Minetto, M.3    Orecchia, S.4    Cilli, M.5    Gaudino, G.6
  • 29
    • 0032960121 scopus 로고    scopus 로고
    • Flt3 ligand can promote survival and macrophage development without proliferation in myeloid progenitor cells
    • Nicholls, S. E., Winter, S., Mottram, R., Miyan, J. A. Whetton, A. D. (1999) Flt3 ligand can promote survival and macrophage development without proliferation in myeloid progenitor cells. Exp. Hematol. 27, 663-672.
    • (1999) Exp. Hematol. , vol.27 , pp. 663-672
    • Nicholls, S.E.1    Winter, S.2    Mottram, R.3    Miyan, J.A.4    Whetton, A.D.5
  • 30
    • 0020078038 scopus 로고
    • Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy
    • Tushinski, R. J., Oliver, I. T., Guilbert, L. J., Tynan, P. W., Warner, J. R., Stanley, E. R. (1982) Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy. Cell 28, 71-81.
    • (1982) Cell , vol.28 , pp. 71-81
    • Tushinski, R.J.1    Oliver, I.T.2    Guilbert, L.J.3    Tynan, P.W.4    Warner, J.R.5    Stanley, E.R.6
  • 31
    • 0027244724 scopus 로고
    • Inflammation, immunoregulation, and inducible nitric oxide synthase
    • Nussler, A. K., Biliar, T. R. (1993) Inflammation, immunoregulation, and inducible nitric oxide synthase. J. Leukoc. Biol. 54, 171-178.
    • (1993) J. Leukoc. Biol. , vol.54 , pp. 171-178
    • Nussler, A.K.1    Biliar, T.R.2
  • 34
    • 0033456158 scopus 로고    scopus 로고
    • FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis
    • Perlman, H., Pagliari, L. J., Georganas, C., Mano, T., Walsh, K., Pope, R. M. (1999) FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis. J. Exp. Med. 190, 1679-1688.
    • (1999) J. Exp. Med. , vol.190 , pp. 1679-1688
    • Perlman, H.1    Pagliari, L.J.2    Georganas, C.3    Mano, T.4    Walsh, K.5    Pope, R.M.6
  • 35
    • 0344766073 scopus 로고    scopus 로고
    • Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages
    • Hortelano, S., Lopez-Collazo, E., Bosca, L. (1999) Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages. Br. J. Pharmacol. 126, 1139-1146.
    • (1999) Br. J. Pharmacol. , vol.126 , pp. 1139-1146
    • Hortelano, S.1    Lopez-Collazo, E.2    Bosca, L.3
  • 37
    • 0032741542 scopus 로고    scopus 로고
    • Negative regulation of macrophage activation in response to IFN-γ and lipopolysaccharide by the STK/RON receptor tyrosine kinase
    • Liu, Q-P., Fruit, K., Ward, J., Correll, P. H. (1999) Negative regulation of macrophage activation in response to IFN-γ and lipopolysaccharide by the STK/RON receptor tyrosine kinase. J. Immunol. 163, 6606-6613.
    • (1999) J. Immunol. , vol.163 , pp. 6606-6613
    • Liu, Q.-P.1    Fruit, K.2    Ward, J.3    Correll, P.H.4
  • 38
    • 0344761911 scopus 로고    scopus 로고
    • Activation of caspase 3 during Legionella pneumophila-induced apoptosis
    • Gao, L.Y., Abu Kwaik, Y. (1999) Activation of caspase 3 during Legionella pneumophila-induced apoptosis. Infect. Immun. 67, 4886-4894.
    • (1999) Infect. Immun. , vol.67 , pp. 4886-4894
    • Gao, L.Y.1    Abu Kwaik, Y.2
  • 39
    • 0032935396 scopus 로고    scopus 로고
    • The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism
    • Sevilla, L., Aperlo, C., Dulic, V., Chambard, J. C., Boutonnet, C., Pasquier, O., Pognonec, P., Boulukos, K. E. (1999) The Ets2 transcription factor inhibits apoptosis induced by colony-stimulating factor 1 deprivation of macrophages through a Bcl-xL-dependent mechanism. Mol. Cell. Biol. 19, 2624-2634.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2624-2634
    • Sevilla, L.1    Aperlo, C.2    Dulic, V.3    Chambard, J.C.4    Boutonnet, C.5    Pasquier, O.6    Pognonec, P.7    Boulukos, K.E.8
  • 42
    • 0033538443 scopus 로고    scopus 로고
    • Activation of the cell death program by nitric oxide involves inhibition of the proteasome
    • Glockzin, S., von Knethen, A., Scheffner, M., Brune, B. (1999) Activation of the cell death program by nitric oxide involves inhibition of the proteasome. J. Biol. Chem. 274, 19581-19586.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19581-19586
    • Glockzin, S.1    Von Knethen, A.2    Scheffner, M.3    Brune, B.4
  • 43
    • 0032929762 scopus 로고    scopus 로고
    • Signaling through phosphoinositide 3-kinases: The lipids take center stage
    • Leevers, S. J., Vanhaesebroeck, B., Waterfield, M. D. (1999) Signaling through phosphoinositide 3-kinases: the lipids take center stage. Curr. Opin. Cell Biol. 11, 219-225.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 219-225
    • Leevers, S.J.1    Vanhaesebroeck, B.2    Waterfield, M.D.3
  • 44
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor
    • Yao, R., Cooper, G. M. (1995) Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 267, 2003-2006.
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2
  • 45
    • 0032528851 scopus 로고    scopus 로고
    • Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway
    • Koh, J. S., Lieberthal, W., Heydrick, S., Levine, J. S. (1998) Lysophosphatidic acid is a major serum noncytokine survival factor for murine macrophages which acts via the phosphatidylinositol 3-kinase signaling pathway. J. Clin. Investig. 102, 716-727.
    • (1998) J. Clin. Investig. , vol.102 , pp. 716-727
    • Koh, J.S.1    Lieberthal, W.2    Heydrick, S.3    Levine, J.S.4
  • 46
    • 0029838319 scopus 로고    scopus 로고
    • Requirement of phosphatidylinositol-3 kinase for epithelial cell migration activated by human macrophage stimulating protein
    • Wang, M. H., Montero-Julian, F. A., Dauny, I., Leonard, E. J. (1996) Requirement of phosphatidylinositol-3 kinase for epithelial cell migration activated by human macrophage stimulating protein. Oncogene 13, 2167-2175.
    • (1996) Oncogene , vol.13 , pp. 2167-2175
    • Wang, M.H.1    Montero-Julian, F.A.2    Dauny, I.3    Leonard, E.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.