The ambiguous role of the Na+-H+ exchanger isoform 1 (NHE1) in leptin-induced oxidative stress in human monocytes

Cell Stress and Chaperones

Volumn 14, Issue 6, 2009, Pages 591-601

  Konstantinidis, Diamantis ^a   Paletas, Konstantinos ^b   Koliakos, George ^b   Kaloyianni, Martha ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Atherosclerosis; Leptin; Monocytes; NHE1; Oxidative stress; Signaling

Indexed keywords

CARIPORIDE; DICHLORODIHYDROFLUORESCEIN DIACETATE; HYDROETHIDINE; LEPTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SODIUM PROTON EXCHANGE PROTEIN 1; SUPEROXIDE DISMUTASE; WORTMANNIN;

ARTICLE; CELL PH; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPERLEPTINEMIA; MONOCYTE; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CATION TRANSPORT PROTEINS; ETHIDIUM; FLUORESCEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LEPTIN; MONOCYTES; NADPH OXIDASE; OXIDATIVE STRESS; PROTEIN KINASE C; SIGNAL TRANSDUCTION; SODIUM-HYDROGEN ANTIPORTER; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 77950867191     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-009-0110-4     Document Type: Article

References (45)

1. Ahima RS, Osei SY (2004) Leptin signaling. Physiol Behav 81(2): 223-241. doi:10.1016/j.physbeh.2004.02.014
2. Auwerx J, Staels B (1998) Leptin. Lancet 351(9104): 737-742. doi: 10.1016/S0140-6736(97) 06348-4
3. Bouloumie A, Marumo T, Lafontan M, Busse R (1999) Leptin induces oxidative stress in human endothelial cells. FASEB J 13(10): 1231-1238 (Pubitemid 29300368)
4. + antiport activity by adrenaline on erythrocytes from normal and obese individuals. MoI Cell Endocrinol. 205(1-2): 141-150. doi: 10.1016/S0303-7207(03) 00092-3
5. Cathcart MK (2004) Regulation of superoxide anion production by NADPH oxidase in monocytes/macrophages: contributions to atherosclerosis. Arterioscler Thromb Vase Biol 24: 23-28. doi: 10.1161/01.ATV.0000097769.47306.12 (Pubitemid 38082407)
6. Choudhury RP, Lee JM, Greaves DR (2005) Mechanisms of disease: macrophage-derived foam cells emerging as therapeutic targets in atherosclerosis. Nat Clin Pract Cardiovasc Med 2(6): 309-315. doi:10.1038/ncpcardio0195
7. Considine RV, Sinha MK, Heiman ML, Kriaucinas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL et al (1996) Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334(5): 292-295. doi: 10.1056/NEJM199602013340503
8. Demaurex N, Downey GP, Waddell TK, Grinstein S (1996) Intracellular pH regulation spreading of human neutrophils. J Cell Biol 133(6): 1391-1402. doi: 10.1083/jcb.133.6.1391 (Pubitemid 26192338)
9. Dimmeler S, Zeiher AM (2000) Reactive oxygen species and vascular cell apoptosis in response to angiotensin II and proatherosclerotic factors. Regul Pept 90(1-3): 19-25. doi:10.1016/S0167-0115(00) 00105-1 (Pubitemid 30331005)
10. Dong F, Zhang X, Ren J (2006) Leptin regulates cardiomyocyte contractile function through endotlielin-1 receptor-NADPH oxiase pathway. Hypertension 47(2): 222-229. doi:10.1161/01.HYP.0000198555.51645.fl (Pubitemid 43189767)
11. Giorgio M, Trinei M, Migliaccio E, Pelicci PG (2007) Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? Nat Rev MoI Cell Biol 8(9): 722-728. doi:10.1038/nrm2240
12. Glass CK, Witztum JT.. (2001) Atherosclerosis: the road ahead. Cell 104: 503-516. doi:10.1016/S0092-8674(01) 00238-0
13. Gomes A, Fernandes E, Lima JL (2005) Fluorescence probes used for detection of reactive oxygen species. J Biochem Biophys Methods 65(2-3): 45-80. doi:10.1016/j.jbbm.2005.10.003 (Pubitemid 41827578)
14. Gregory CD, Devitt A (2004) The macrophage and. the apoptotic cell: an innate immune interaction viewed simplistically? Immunology 113(1): 1-14. doi:10.1111/j.1365-2567.2004.01959.x
15. Guo S, Wharton W, Mosely P, Shi H (2007) Heat shock protein 70 regulates cellular redox status by modulating glutathione-related enzyme activities. Cell Stress Chaperones 12(3): 245-254. doi:10.1379/CSC-265.1 (Pubitemid 351199387)
16. Gutierrez J, Ballinger SW, Darley-Usmar VM, Laudar A (2006) Free radicals, mitochondria and oxidized lipids. The emerging role in signal transduction in vascular cells. Circ Res 99: 924-932. doi:10.1161/01.RES. 0000248212.86638.e9
17. Hancock JT, Desikan R, Neil SJ (2001) Role of reactive oxygen species in cell signalling pathways. Biochem Soc Trans 29(Pt 2): 345-350. doi:10.1042/BST0290345 (Pubitemid 32587530)
18. + exchange. Immunobiology 207(2): 141-148. doi: 10.1078/0171-2985-00224
19. + antiport by insulin: interplay between protein kinase C, tyrosine kinase, and protein phosphatases. J Cell Physiol 159: 205-212. doi:10.1002/jcp.1041590203
20. Koliakos G, Zolota Z, Paletas K, Kaloyianni M (2004) High glucose concentrations stimulate human monocyte sodium/hydrogen exchanger activity and modulate atherosclerosis-related functions. Pflügers Arch 449(3): 298-306 (Pubitemid 40064621)
21. Koliakos G, Paletas K, Kaloyianni M (2008) NHE-1: a molecular target for signalling and cell matrix interactions. Connect Tissue Res 49(3): 157-161. doi: 10.1080/03008200802151581
22. Konstantinidis D, Koliakos G, Paletas K, Kaloyianni M (2009) Signaling components involved, in leptin-induced amplification of human monocyte atherosclerosis-related properties. J Vase Res 46(3): 199-208. doi: 10.1159/000161234
23. + exchanger isoform-1 and the extracellular signal-regulated kinase induces apoptosis: a time course of events. Cell Physiol Biochem 18(4-5): 211-222. doi: 10.1159/000097668
24. + antiport (NHE1) activity of obese and normal subjects erythrocytes. MoI Cell Endocrinol 183(1-2): 11-18. doi: 10.1016/S0303-7207(01)00639-6
25. Korda M, Kubant R, Patton S, Malinski T (2008) Leptin-induced endothelial dysfunction in obesity. Am J Physiol Heart Circ Physiol 295(4): H1514-1521. doi:10.1152/ajpheart.00479.2008
26. + exchanger. Can J Physiol Pharmacol 84(11): 1081-1095.
27. + exchanger NHEl. FEBS Lett 521(1-3): 205-210.doi: 10.1016/S0014-5793(02) 02867-2873
28. Martin-Romero C, Sanchez-Margalet V (2001) Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68. Cell Immunol 212(2): 83-91. doi:10.1006/cimm.2001.1851 (Pubitemid 34044539)
29. Peelman F, Waelput W, Iserentant H, Lavens D, Eyckerman S, Zabeau L, Tavemier J (2004) Leptin: linking adipocyte metabolism with, cardiovascular and autoimmune diseases. Prog Lipid Res 43 (4): 283-301. doi:10.1016/j.plipres.2004. 03.001 (Pubitemid 38952616)
30. Peskin AV, Winterbourn CC (2000) A microliter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1). Clin Chim Acta 293(1-2): 157-166. doi:10.1016/S0009-8981(99)00246-6
31. + exchanger, NHE1: structure, regulation and cellular actions. Annu Rev Pharmacol Toxicol 42: 527-552. doi: 10.1146/annurev.pharmtox. 42.092001.143801
32. +-ATPaSe stabilization by Hsp70 in the outer stripe of the outer medulla in rats during recovery from a low-protein diet. Cell Stress Chaperones 13 (2): 157-167. doi:10.1007/s12192-008-0021-9
33. Sanchez-Pozo C, Rodriguez-Bano J, Dominguez-Castellano A, Muniain MA, Goberna R, Sanchez-Margalet V (2003) Leptin stimulates the oxidative burst in monocytes from HIV-infected patients. Clin Exp Immunol. 134(3): 464-469. doi:10.1111/j.1365-2249.2003.02321.x
34. Schroeter MR, Leifneit M, Sudholt P, Heida NM, Dellas C, Rohm I, Alves F, Zientkowska M, Rafail S, Puls M, Hasenfuss G, Konstantinides S, Schäfer K (2008) Leptin enhances the recruitment of endothelial progenitor cells into neointimal lesions after vascular injury by promoting integrin-mediated adhesion. Circ Res 103(5): 536-544. doi:10.1161/CIRCRESAHA.107.1.69375
35. Seager-Danciger J, Lutz M, Hama S, Cruz D, Castrillo A, Lazara J, Phillips R, Premack B, Berliner J (2004) Method for large scale isolation, culture and cryopreservation of human monocytes suitable for Chemotaxis, cellular adhesion assays, macrophage and dendritic cell differentiation. J Immunol Methods 288(1-2): 123-134. doi:10.1016/j.jim.2004.03.003 (Pubitemid 38739258)
36. Suzuki S, Maruyama S, Sato W, Morita Y, Sato F, Mild Y, Kato S, Katsuno M, Sobue G, Yuzawa Y, Matsuo S (2005) Geranylgeranylacetone ameliorates ischemic acute renal failure via induction of Hsp70. Kidney Int 67: 2210-2220. doi:10.1111/j.1523-1755.2005.00326.x (Pubitemid 41623382)
37. Sweeney G (2002) Leptin signalling. Cell Signal. 14(8): 655-663. doi: 10.1016/S0898-6568(02)00006-2
38. Tilomas JA, Buchsbaum RN, Zimniak A, Racker E (1979) Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 18: 2210-2218. doi:10.1021/bi00578a012 (Pubitemid 9191034)
39. Touyz RM (2003) Reactive oxygen species in vascular biology: role in arterial hypertension. Expert Rev Cardiovasc Ther 1(1): 91-106. doi:10.1586/14779072.1.1.91
40. Wardman P (2007) Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls and prospects. Free Radic Biol Med 43(7): 995-1022. doi:10.1016/j.freeradbiomed. 2007.06.026
41. + exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival. J Biol Chem 279(25): 26280-26286. doi:10.1074/jbc.M400814200
42. Xu L, Giffard RG (1997) HSP70 protects murine astrocytes from glucose deprivation injury. Neurosci Lett 224(1): 9-12. doi:10.1016/80304-3940(97)13444- 9 (Pubitemid 27112857)
43. Zarkesh-Esfahani H, Pockley G, Metcalfe RA, Bidlingmaier M, Wu. Z, Ajami A, Weetman AP, Strasburger CJ, Ross RJ (2001) Highdose leptin activates human, leukocytes via receptor expression on monocytes. J Immunol 167: 4593-4599 (Pubitemid 32954339)
44. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372(6505): 425-432. doi:10.1038/372425a0 (Pubitemid 24365442)
45. Zhao H, Joseph J, Fales HM, Sokoloski EA, Levine RL, Vasquez-Vivar J, Kalyanaraman B (2005) Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitation of fluorescence. Proc Natl Acad Sci USA 102(16): 5727-5732. doi:10.1073/pnas. 0501719102 (Pubitemid 40559627)