X-ray structure and characterization of carbamate kinase from the human parasite Giardia lamblia

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 66, Issue 4, 2010, Pages 386-390

  Galkin, Andrey ^a   Kulakova, Liudmila ^a   Wu, Rui ^b   Nash, Theodore E ^c   Dunaway Mariano, Debra ^b   Herzberg, Osnat ^a  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Arginine dehydrolase pathway; Carbamate kinases; Drug targets; Giardia lamblia

Indexed keywords

CARBAMATE KINASE; CARBAMOYL PHOSPHATE; GLYCEROL; PHOSPHOTRANSFERASE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; GIARDIA LAMBLIA; ISOLATION AND PURIFICATION; METABOLISM; PROTEIN QUATERNARY STRUCTURE; STRUCTURAL HOMOLOGY; X RAY CRYSTALLOGRAPHY;

CARBAMYL PHOSPHATE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; GIARDIA LAMBLIA; GLYCEROL; MODELS, MOLECULAR; PHOSPHOTRANSFERASES (CARBOXYL GROUP ACCEPTOR); PROTEIN STRUCTURE, QUATERNARY; STRUCTURAL HOMOLOGY, PROTEIN;

GIARDIA; GIARDIA INTESTINALIS;

EID: 77950816773     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309110004665     Document Type: Article

References (25)

1. Adam, R. D. (2001). Clin. Microbiol. Rev. 14, 447-475.
2. Bernstein, E., Denli, A. M. & Hannon, G. J. (2001). RNA, 7, 1509-1521.
3. Biagini, G. A., Yarlett, N., Ball, G. E., Billetz, A. C., Lindmark, D. G.,Martinez, M. P., Lloyd, D. & Edwards, M. R. (2003). Mol. Biochem. Parasitol. 128, 11-19.
4. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T. & Warren, G. L. (1998). Acta Cryst. D54, 905-921.
5. Durbecq, V., Legrain, C., Roovers, M., Pierard, A. & Glansdorff, N. (1997). Proc. Natl Acad. Sci. USA, 94, 12803-12808.
6. Galkin, A., Kulakova, L., Melamud, E., Li, L., Wu, C., Mariano, P., Dunaway-Mariano, D., Nash, T. E. & Herzberg, O. (2007). J. Biol. Chem. 282, 4859-4867.
7. Galkin, A., Kulakova, L., Wu, R., Gong, M., Dunaway-Mariano, D. & Herzberg, O. (2009). Proteins, 76, 1049-1053.
8. Holm, L. & Sander, C. (1993). J. Mol. Biol. 233, 123-138.
9. Kleywegt, G. J. & Jones, T. A. (1999). Acta Cryst. D55, 941-944.
10. Knodler, L. A., Sekyere, E. O., Stewart, T. S., Schofield, P. J. & Edwards, M. R. (1998). J. Biol. Chem. 273, 4470-4477.
11. Knowles, J. R. (1980). Annu. Rev. Biochem. 49, 877-919.
12. Li, Z., Kulakova, L., Li, L., Galkin, A., Zhao, Z., Nash, T. E., Mariano, P. S., Herzberg, O. & Dunaway-Mariano, D. (2009). Bioorg. Chem. 37, 149-161.
13. Marina, A., Alzari, P. M., Bravo, J., Uriarte,M., Barcelona, B., Fita, I. & Rubio, V. (1999). Protein Sci. 8, 934-940.
14. Marshall, M. & Cohen, P. P. (1966). J. Biol. Chem. 241, 4233-4242.
15. McCoy, A. J., Grosse-Kunstleve, R. W., Storoni, L. C. & Read, R. J. (2005). Acta Cryst. D61, 458-464.
16. Minotto, L., Tutticci, E. A., Bagnara, A. S., Schofield, P. J. & Edwards, M. R. (1999). Mol. Biochem. Parasitol. 98, 43-51.
17. Murshudov, G. N., Vagin, A. A. & Dodson, E. J. (1997). Acta Cryst. D53, 240-255.
18. Nallamsetty, S., Austin, B. P., Penrose, K. J. & Waugh, D. S. (2005). Protein Sci. 14, 2964-2971.
19. Nallamsetty, S., Kapust, R. B., Tozser, J., Cherry, S., Tropea, J. E., Copeland, T. D. & Waugh, D. S. (2004). Protein Expr. Purif. 38, 108-115.
20. Palm, J. E., Weiland, M. E., Griffiths, W. J., Ljungstrom, I. & Svä rd, S. G. (2003). J. Infect. Dis. 187, 1849-1859.
21. Ramon-Maiques, S., Marina, A., Uriarte, M., Fita, I. & Rubio, V. (2000). J. Mol. Biol. 299, 463-476.
22. Schofield, P. J., Edwards, M. R., Matthews, J. & Wilson, J. R. (1992). Mol. Biochem. Parasitol. 51, 29-36.
23. Su, L.-H., Lee, G. A., Huang, Y.-C., Chen, Y.-H. & Sun, C.-H. (2007). Mol. Biochem. Parasitol. 156, 124-135.
24. Touz, M. C., Kulakova, L. & Nash, T. E. (2004). Mol. Biol. Cell, 15, 3053-3060.
25. Wieder, S. C., Keister, D. B. & Reiner, D. S. (1983). J. Parasitol. 69, 1181-1182.