Bacterial-like energy metabolism in the amitochondriate protozoon Hexamita inflata

Molecular and Biochemical Parasitology

Volumn 128, Issue 1, 2003, Pages 11-19

  Biagini, Giancarlo A ^a,e   Yarlett, Nigel ^b   Ball, Graham E ^a   Billetz, Ann C ^c   Lindmark, Donald G ^c   Martinez, Martha P ^b   Lloyd, David ^d   Edwards, Michael R ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b PACE UNIVERSITY   (United States)

^c CLEVELAND STATE UNIVERSITY   (United States)

^d CARDIFF UNIVERSITY   (United Kingdom)

^e LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

Anaerobic; Arginine dihydrolase pathway; Giardia; Parasite; Polyamines; Protozoa

Indexed keywords

ACETIC ACID; ALANINE; ALCOHOL; ARGININE DEIMINASE; CARBAMATE KINASE; CARBON DIOXIDE; ISOENZYME; LACTIC ACID; MALTOSE; ORNITHINE CARBAMOYLTRANSFERASE; ORNITHINE DECARBOXYLASE; OXIDE; OXYGEN; POLYAMINE DERIVATIVE; PROPANE; PUTRESCINE; S ADENOSYLMETHIONINE; SPERMIDINE; SPERMINE; SYNTHETASE;

AMINO ACID ANALYSIS; AMINO ACID SYNTHESIS; AMMONIA FORMATION; ARTICLE; BACTERIUM; CALCULATION; CARBOHYDRATE METABOLISM; CARBON SOURCE; CATABOLISM; CELL TYPE; CONCENTRATION RESPONSE; DEAMINATION; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME ASSAY; HEXAMITA INFLATA; METABOLITE; MICROBIAL GROWTH; MICROBIAL METABOLISM; MITOCHONDRION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PROTOZOON;

ARCHEZOA; BACTERIA (MICROORGANISMS); GIARDIA; HEXAMITA INFLATA; PROTOZOA;

EID: 12444269990     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(03)00025-2     Document Type: Article

References (38)

1. Dando P.R., Fenchel T., Jensen P., O'Hara S.C.M., Niven S.J., Schuster U. Ecology of gassy, organic-rich sediment in a shallow subtidal area on the Kattegat coast of Denmark. Mar. Ecol. Prog. Ser. 100:1993;265-271.
2. Fenchel T., Bernard C., Esteban G., Finlay B.J., Hansen P.J., Iversen N. Microbial diversity and activity in a Danish fijord with anoxic deep water. Ophelia. 43:1995;45-100.
3. Mylnikov AP. Diversity of flagellates without mitochondria. In: Patterson DJ, Larsen J, editors. The biology of free-living heterotrophic flagellates. Oxford, UK: Claredon Press; 1991. p. 149-58.
4. Biagini G.A., Finlay B.J., Lloyd D. Protozoan stimulation of anaerobic microbial activity: enhancement of the rate of terminal decomposition of organic matter. FEMS Microbiol. Ecol. 27:1998;1-8.
5. Fenchel T, Finlay BJ. Ecology and evolution in anoxic worlds. Oxford: Oxford University Press; 1995.
6. Buchmann K., Uldal A., Lyholt H.C.K. Parasite infections in Danish Trout farms. Acta Vet. Scand. 36:1995;283-298.
7. Kulda J, Nohýnková E. Flagellates of the human intestine and of the intestines of other species. In: Kreier JP, editor. Parasitic protozoa. New York: Academic Press; 1978. p. 2-127.
8. Poynton S.L., Sterud E. Guidelines for species descriptions of diplomonad flagellates from fish. J. Fish Dis. 25:2002;15-31.
9. Van Keulen H., Guttel R.R., Gates M.A.et al. Unique phylogenetic position of diplomonadida based on the complete small subunit ribosomal RNA sequence of Giardia ardea, G. muris, G. duodenalis and Hexamita sp. FASEB J. 7:1993;223-231.
10. Leipe D.D., Gunderson J.H., Nerad T.A., Sogin M.L. Small subunit ribosomal RNA of Hexamita inflata and the quest for the first bunch of the eukaryotic tree. Mol. Biochem. Parasitol. 59:1993;41-48.
11. Brugerolle G. Contribution a l'étude cytologique et phylétiqu des diplozaires (zoomastigophorea, diplozoa, Dngeard 1910). Protistologica. 1:1974;83-90.
12. Biagini G.A., Suller M.T.E., Finlay B.J., Lloyd D. Oxygen uptake and antioxidant responses of the free-living diplomonad Hexamita sp. J. Euk. Microbiol. 44:1997;447-453.
13. Phillips N.F., Li Z., Lindmark D.G. Isolation of a pyrophosphate-dependent phosphofructokinase from Hexamita inflata. Mol. Biochem. Parasitol. 90:1997;377-380.
14. Biagini G.A., McIntyre P.S., Finlay B.J., Lloyd D. Carbohydrate and amino acid fermentation in the free-living primitive protozoon Hexamita sp. Appl. Environ. Microbiol. 64:1998;203-207.
15. Biagini G.A., Rutter A.J., Finlay B.J., Lloyd D. Lipids and lipid metabolism in themicroaerobic free-living diplomonad Hexamita sp. Eur. J. Parasitol. 34:1998;148-152.
16. Dimopoulos M., Bagnara A.S., Edwards M.R. Characterisation and sequence analysis of a carbamate kinase gene from the diplomonad Hexamita inflata. J. Eukaryot. Microbiol. 47:2000;499-503.
17. Linstead D., Cranshaw M. The pathway of arginine catabolism in the parasitic flagellate Trichomonas vaginalis. Mol. Biochem. Parasitol. 8:1983;241-252.
18. Yarlett N., Lindmark D.G., Goldberg B., Ali Moharrami M., Bacchic C.J. Subcellular localisation of the enzymes of the arginine dihydrolase pathway in Trichomonas vaginalis and Tritrichomonas foetus. J. Euk. Microbiol. 41:1994;554-559.
19. Schofield P.J., Costello M., Edwards M.R., O'Sullivan W.J. The arginine dihydrolase pathway is present in Giardia intestinalis. Int. J. Parasitol. 20:1990;697-699.
20. North M.J., Lockwood B.C., Bremmer A.F., Coombs G.H. Polyamine biosynthesis in trichomonads. Mol. Biochem. Parasitol. 19:1986;241-249.
21. Yarlett N., Bacchi C.J. Effect of DL-α-difluoromethylornithine on polyamine synthesis and interconversion in Trichomonas vaginalis grown in a semi-defined medium. Mol. Biochem. Parasitol. 31:1988;1-10.
22. Gillin F.D., Reiner D.S., McCann P.P. Inhibition of growth of Giardia lamblia by difluoromethylornithine, a specific inhibitor of polyamine biosynthesis. J. Protozool. 31:1984;161-163.
23. Gilroy F.V., Edwards M.R., Norton R.S., O'Sullivan W.J. Metabolic studies of the protozoan parasite, Crithidia luciliae, using proton nuclear magnetic resonance spectroscopy. Mol. Biochem. Parasitol. 31:1988;107-116.
24. Edwards M.R., Gilroy F.V., Jimenez B.M., O'Sullivan W.J. Alanine is a major end-product of metabolism by Giardia lamblia: a proton nuclear magnetic resonance study. Mol. Biochem. Parasitol. 37:1989;19-26.
25. Knodler L.A., Edwards M.R., Schofield P.J. The intracellular amino acid pools of Giardia intestinalis, Trichomonas vaginalis and Crithidia luciliae. Exp. Parasitol. 79:1994;117-125.
26. + and amino acids in osmoregulation by the free-living microaerophilic protozoon Hexamita inflata. Microbiology. 146:2000;427-433.
27. Boyde R.R.C., Rahmatullah M. Optimization of conditions for the colorimetric determination of citrulline using diacetyl monoxamine. Anal. Biochem. 107:1980;424-431.
28. Lowry O.H., Rosenbrough N.H., Farr A.L., Randall R.J. Protein measurement with Folin reagent. J. Biol. Chem. 193:1951;265-275.
29. Yarlett N., Martinez M.P., Moharami M.A., Tachezy J. The contribution of the arginine dihydrolase pathway to energy metabolism by Trichomonas vaginalis. Mol. Biochem. Parasitol. 78:1996;117-125.
30. Schofield P.J., Edwards M.R., Matthews J., Wilson J.R. The pathway of arginine catabolism in Giardia intestinalis. Mol. Biochem. Parasitol. 51:1992;29-36.
31. Cross DS, Zalitis JG. Interaction of fuels in diplomonads, Giardia and Hexamita on growth and glycogen levels. Abstract of the 51st Annual Meeting of the Society for Protozoologists; 1-8 August 1998 ( www.jeukmic.org ).
32. Gottschalk G. Bacterial metabolism. New York: Springer; 1986.
33. Sussenbach J.S., Strijkert P.J. Arginine metabolism in Chlamydomonas reinhardtii. FEBS Lett. 3:1969;166-168.
34. Lindmark DG, Billetz AC, Dietrich BH, Van Kuelen H, Yarlett N. Hexamita inflata: the arginine dihydrolase pathway and other selected enzyme activities. Abstract of the 51st Annual Meeting of the Society for Protozoologists; 1-8 August 1998 ( www.jeukmic.org ).
35. Paget T.A., Raynor M.H., Shipp D.W., Lloyd D. Giardia lamblia produces alanine anaerobically but not in the presence of oxygen. Mol. Biochem. Parasitol. 42:1990;63-67.
36. Paget T.A., Kelly M.L., Jarroll E.L., Lindmark D.G., Lloyd D. The effects of oxygen on fermentation in Giardia lamblia. Mol. Biochem. Parasitol. 57:1993;65-72.
37. Lloyd D, Harris JC, Biagini GA, et al. Oxygen homeodynamics in Giardia. In: Olson BE, Olson ME, Wallis PM, editors. Giardia: the cosmopolitan parasite. UK: CAB International; 2002. p. 29-43.
38. Cedar H., Schwartz J.H. Production of L-asparaginase II by Escherichia coli. J. Bacteriol. 96:1968;2043-2048.