메뉴 건너뛰기




Volumn 10, Issue 2, 2010, Pages 242-267

The biology of the sodium iodide symporter and its potential for targeted gene delivery

Author keywords

Adenovirus; Gene therapy; Measles virus; Radioiodide; Radiotherapy; Sodium iodide symporter

Indexed keywords

IODINE 124; IODINE 125; IODINE 131; RADIOISOTOPE; RHENIUM 186; SODIUM IODIDE SYMPORTER; TECHNETIUM 99M; TROGLITAZONE; VIRUS VECTOR;

EID: 77950687906     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800910791054194     Document Type: Review
Times cited : (119)

References (194)
  • 2
    • 4444242256 scopus 로고    scopus 로고
    • Thyroid cancer: An overview
    • Haq, M. S.; Harmer, C. Thyroid cancer: an overview. Nucl. Med. Commun. 2004, 25, 861-867.
    • (2004) Nucl. Med. Commun. , vol.25 , pp. 861-867
    • Haq, M.S.1    Harmer, C.2
  • 4
  • 5
    • 0030800654 scopus 로고    scopus 로고
    • Thyroid Na+/I- Symporter. Mechanism, stoichiometry, and specificity
    • Eskandari, S.; Loo, D. D.; Dai, G.; Levy, O.; Wright, E. M.; Carrasco, N. Thyroid Na+/I- symporter. Mechanism, stoichiometry, and specificity. J. Biol. Chem. 1997, 272, 27230-27238.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27230-27238
    • Eskandari, S.1    Loo, D.D.2    Dai, G.3    Levy, O.4    Wright, E.M.5    Carrasco, N.6
  • 6
    • 0032901865 scopus 로고    scopus 로고
    • The Pendred syndrome gene encodes a chloride-iodide transport protein
    • Scott, D. A.; Wang, R.; Kreman, T. M.; Sheffield, V. C.; Karniski, L. P. The Pendred syndrome gene encodes a chloride-iodide transport protein. Nat. Genet. 1999, 21, 440-443.
    • (1999) Nat. Genet , vol.21 , pp. 440-443
    • Scott, D.A.1    Wang, R.2    Kreman, T.M.3    Sheffield, V.C.4    Karniski, L.P.5
  • 7
    • 38049115321 scopus 로고    scopus 로고
    • The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate
    • Dohán, O.; Portulano, C.; Basquin, C.; Reyna-Neyra, A.; Amzel, L. M.; Carrasco, N. The Na+/I symporter (NIS) mediates electroneutral active transport of the environmental pollutant perchlorate. Proc. Natl. Acad. Sci. USA 2007, 104, 20250-20255.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 20250-20255
    • Dohán, O.1    Portulano, C.2    Basquin, C.3    Reyna-Neyra, A.4    Amzel, L.M.5    Carrasco, N.6
  • 8
    • 33750913836 scopus 로고    scopus 로고
    • Physiology and pathophysiology of the DUOXes
    • Ris-Stalpers, C. Physiology and pathophysiology of the DUOXes. Antioxid Redox Signal. 2006, 8, 1563-1572.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1563-1572
    • Ris-Stalpers, C.1
  • 9
    • 0030053759 scopus 로고    scopus 로고
    • Cloning and characterization of the thyroid iodide transporter
    • Dai, G.; Levy, O.; Carrasco, N. Cloning and characterization of the thyroid iodide transporter. Nature 1996, 379, 458-460.
    • (1996) Nature , vol.379 , pp. 458-460
    • Dai, G.1    Levy, O.2    Carrasco, N.3
  • 12
    • 0030739949 scopus 로고    scopus 로고
    • Expression, exon-intron organization, and chromosome mapping of the human sodium iodide symporter
    • Smanik, P. A.; Ryu, K. Y.; Theil, K. S.; Mazzaferri, E. L.; Jhiang, S. M. Expression, exon-intron organization, and chromosome mapping of the human sodium iodide symporter. Endocrinology 1997, 138, 3555-3558.
    • (1997) Endocrinology , vol.138 , pp. 3555-3558
    • Smanik, P.A.1    Ryu, K.Y.2    Theil, K.S.3    Mazzaferri, E.L.4    Jhiang, S.M.5
  • 14
    • 34548515726 scopus 로고    scopus 로고
    • Amino acid residues in transmembrane segment IX of the Na+/I- Symporter play a role in its Na+ dependence and are critical for transport activity
    • De la Vieja, A.; Reed, M. D.; Ginter, C. S.; Carrasco, N. Amino acid residues in transmembrane segment IX of the Na+/I- symporter play a role in its Na+ dependence and are critical for transport activity. J. Biol. Chem. 2007, 282, 25290-25298.
    • (2007) J. Biol. Chem. , vol.282 , pp. 25290-25298
    • De La Vieja, A.1    Reed, M.D.2    Ginter, C.S.3    Carrasco, N.4
  • 15
    • 0036020509 scopus 로고    scopus 로고
    • Na+/I- Symporter activity requires a small and uncharged amino acid residue at position 395
    • Dohán, O.; Gavrielides, M. V.; Ginter, C.; Amzel, L. M.; Carrasco, N. Na+/I- symporter activity requires a small and uncharged amino acid residue at position 395. Mol. Endocrinol. 2002, 16, 1893-1902.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1893-1902
    • Dohán, O.1    Gavrielides, M.V.2    Ginter, C.3    Amzel, L.M.4    Carrasco, N.5
  • 16
    • 0033049567 scopus 로고    scopus 로고
    • The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription
    • Ohno, M.; Zannini, M.; Levy, O.; Carrasco, N.; Di Lauro, R. The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription. Mol. Cell. Biol. 1999, 19, 2051-2060.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2051-2060
    • Ohno, M.1    Zannini, M.2    Levy, O.3    Carrasco, N.4    Di Lauro, R.5
  • 17
    • 0032807749 scopus 로고    scopus 로고
    • Protein kinase A-dependent and - Independent signaling pathways contribute to cyclic AMP-stimulated proliferation
    • Cass, L. A.; Summers, S. A.; Prendergast, G. V.; Backer, J. M.; Birnbaum, M. J.; Meinkoth, J. L. Protein kinase A-dependent and - independent signaling pathways contribute to cyclic AMP-stimulated proliferation. Mol. Cell Biol. 1999, 19, 5882-5891.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 5882-5891
    • Cass, L.A.1    Summers, S.A.2    Prendergast, G.V.3    Backer, J.M.4    Birnbaum, M.J.5    Meinkoth, J.L.6
  • 18
    • 0028838088 scopus 로고
    • A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase
    • Armstrong, R.; Wen, W.; Meinkoth, J.; Taylor, S.; Montminy, M. A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A. Mol. Cell. Biol. 1995, 15, 1826-1832.
    • (1995) A. Mol. Cell. Biol. , vol.15 , pp. 1826-1832
    • Armstrong, R.1    Wen, W.2    Meinkoth, J.3    Taylor, S.4    Montminy, M.5
  • 19
    • 0036794305 scopus 로고    scopus 로고
    • A thyroid-specific far upstream enhancer in the human sodium/ iodide symporter gene requires Pax-8 binding and cyclic adenosine 3', 5'-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells
    • Taki, K.; Kogai, T.; Kanamoto, Y.; Hershman, J. M.; Brent, G. A. A thyroid-specific far upstream enhancer in the human sodium/ iodide symporter gene requires Pax-8 binding and cyclic adenosine 3', 5'-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells. Mol. Endocrinol. 2002, 16, 2266-2282.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 2266-2282
    • Taki, K.1    Kogai, T.2    Kanamoto, Y.3    Hershman, J.M.4    Brent, G.A.5
  • 20
    • 0034753081 scopus 로고    scopus 로고
    • Thyrotropin activates mitogen-activated protein kinase pathway in FRTL-5 by a cAMP-dependent protein kinase A-independent mechanism
    • Iacovelli, L.; Capobianco, L.; Salvatore, L.; Sallese, M.; D'Ancona, G.; De Blasi, A. Thyrotropin activates mitogen-activated protein kinase pathway in FRTL-5 by a cAMP-dependent protein kinase A-independent mechanism. Mol. Pharmacol. 2001, 60, 924-933.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 924-933
    • Iacovelli, L.1    Capobianco, L.2    Salvatore, L.3    Sallese, M.4    D'Ancona, G.5    De Blasi, A.6
  • 21
    • 8344252736 scopus 로고    scopus 로고
    • The CRE-like element inside the 50-upstream region of the rat sodium/ iodide symporter gene interacts with diverse classes of b-Zip molecules that regulate transcriptional activities through strong synergy with Pax-8
    • Chun, J. T.; Di Dato, V.; D'Andrea, B.; Zannini, M.; Di Lauro, R. The CRE-like element inside the 50-upstream region of the rat sodium/ iodide symporter gene interacts with diverse classes of b-Zip molecules that regulate transcriptional activities through strong synergy with Pax-8. Mol. Endocrinol. 2004, 18, 2817-2829.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 2817-2829
    • Chun, J.T.1    Di Dato, V.2    D'Andrea, B.3    Zannini, M.4    Di Lauro, R.5
  • 22
    • 0033779751 scopus 로고    scopus 로고
    • The thyrotropin receptor is not involved in the activation of p42/p44 mitogen-activated protein kinases by thyrotropin preparations in Chinese hamster ovary cells expressing the human thyrotropin receptor
    • Correze, C.; Blondeau, J. P.; Pomerance, M. The thyrotropin receptor is not involved in the activation of p42/p44 mitogen-activated protein kinases by thyrotropin preparations in Chinese hamster ovary cells expressing the human thyrotropin receptor. Thyroid 2000, 10, 747-752.
    • (2000) Thyroid , vol.10 , pp. 747-752
    • Correze, C.1    Blondeau, J.P.2    Pomerance, M.3
  • 23
    • 0033867435 scopus 로고    scopus 로고
    • Thyrotropin-dependent proliferation of in vitro rat thyroid cell systems
    • Medina, D. L.; Santisteban, P. Thyrotropin-dependent proliferation of in vitro rat thyroid cell systems. Eur. J. Endocrinol. 2000, 143, 161-178.
    • (2000) Eur. J. Endocrinol. , vol.143 , pp. 161-178
    • Medina, D.L.1    Santisteban, P.2
  • 24
    • 0034704085 scopus 로고    scopus 로고
    • Thyroid-stimulating hormone and cyclic AMP activate p38 mitogen-activated protein kinase cascade. Involvement of protein kinase A, rac1 and reactive oxygen species
    • Pomerance, M.; Abdullah, H. B.; Kamerji, S.; Correze, C.; Blondeau, J. P. Thyroid-stimulating hormone and cyclic AMP activate p38 mitogen-activated protein kinase cascade. Involvement of protein kinase A, rac1 and reactive oxygen species. J. Biol. Chem. 2000, 25, 40539-40548.
    • (2000) J. Biol. Chem. , vol.25 , pp. 40539-40548
    • Pomerance, M.1    Abdullah, H.B.2    Kamerji, S.3    Correze, C.4    Blondeau, J.P.5
  • 25
    • 0036159928 scopus 로고    scopus 로고
    • PI3K is involved in the IGF-1 inhibition of TSH-induced sodium/iodide symporter gene expression
    • Garcia, B.; Santisteban, P. PI3K is involved in the IGF-1 inhibition of TSH-induced sodium/iodide symporter gene expression. Mol. Endocrinol. 2002, 16, 342-352.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 342-352
    • Garcia, B.1    Santisteban, P.2
  • 26
    • 0034677562 scopus 로고    scopus 로고
    • Ras signaling through PI3K confers hormone-independent proliferation that is compatible with differentiation
    • Cass, L. A.; Meinkoth, J. L. Ras signaling through PI3K confers hormone-independent proliferation that is compatible with differentiation. Oncogene 2000, 19, 924-932.
    • (2000) Oncogene , vol.19 , pp. 924-932
    • Cass, L.A.1    Meinkoth, J.L.2
  • 27
    • 0031762920 scopus 로고    scopus 로고
    • Tumor necrosis factor, ceramide, transforming growth factor-beta1, and aging reduce Na+/I- Symporter messenger ribonucleic acid levels in FRTL-5 cells
    • Pekary, A. E.; Hershman, J. M. Tumor necrosis factor, ceramide, transforming growth factor-beta1, and aging reduce Na+/I- symporter messenger ribonucleic acid levels in FRTL-5 cells. Endocrinology 1998, 139, 703-712.
    • (1998) Endocrinology , vol.139 , pp. 703-712
    • Pekary, A.E.1    Hershman, J.M.2
  • 28
    • 0030753429 scopus 로고    scopus 로고
    • Tumor necrosis factor-alfa (TNF-alfa) and transforming growth factor beta1 (TGF-beta1) inhibit the expression and activity of Na+/K+ATPase in FRTL-5 rat thyroid cells
    • Pekary, A. E.; Levin, S. R.; Johnson, D. G.; Berg, L.; Hershman, J. M. Tumor necrosis factor-alfa (TNF-alfa) and transforming growth factor beta1 (TGF-beta1) inhibit the expression and activity of Na+/K+ATPase in FRTL-5 rat thyroid cells. J. Interferon Cytokine Res. 1997, 4, 185-195.
    • (1997) J. Interferon Cytokine Res. , vol.4 , pp. 185-195
    • Pekary, A.E.1    Levin, S.R.2    Johnson, D.G.3    Berg, L.4    Hershman, J.M.5
  • 29
    • 0942287205 scopus 로고    scopus 로고
    • The functional interaction between the paired domain transcription factor Pax8 and Smad3 is involved in transforming growth factorbeta repression of the sodium/iodide symporter gene
    • Costamagna, E.; Garcia, B.; Santisteban, P. The functional interaction between the paired domain transcription factor Pax8 and Smad3 is involved in transforming growth factorbeta repression of the sodium/iodide symporter gene. J. Biol. Chem. 2004, 279, 3439-3446.
    • (2004) J. Biol. Chem. , vol.279 , pp. 3439-3446
    • Costamagna, E.1    Garcia, B.2    Santisteban, P.3
  • 30
    • 0032522519 scopus 로고    scopus 로고
    • Cloning of a functional promoter of the human sodium/iodide symporter gene
    • Behr, M.; Schmitt, T. L.; Espinoza, C. R.; Loos, U. Cloning of a functional promoter of the human sodium/iodide symporter gene. Biochem. J. 1998, 331, 359-363.
    • (1998) Biochem. J. , vol.331 , pp. 359-363
    • Behr, M.1    Schmitt, T.L.2    Espinoza, C.R.3    Loos, U.4
  • 31
    • 0031741049 scopus 로고    scopus 로고
    • Promoter characterization of the human Na/I symporter
    • Ryu, K. Y.; Tong, Q.; Jhiang, S. M. Promoter characterization of the human Na/I symporter. J. Clin. Endocrinol. Metab. 1998, 83, 3247-3251.
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 3247-3251
    • Ryu, K.Y.1    Tong, Q.2    Jhiang, S.M.3
  • 32
    • 0031561438 scopus 로고    scopus 로고
    • Promoter characterization of the rat Na/I symporter gene
    • Tong, Q.; Ryu, K. Y.; Jhiang, S. M. Promoter characterization of the rat Na/I symporter gene. Biochem. Biophys. Res. Commun. 1997, 239, 34-41.
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 34-41
    • Tong, Q.1    Ryu, K.Y.2    Jhiang, S.M.3
  • 33
    • 0030880728 scopus 로고    scopus 로고
    • Thyroid transcription factor-1 activates the promoter activity of rat Na/I symporter gene
    • Endo, T.; Kaneshige, M.; Nakazato, M.; Ohmori, M.; Harri, N.; Onaya, T. Thyroid transcription factor-1 activates the promoter activity of rat Na/I symporter gene. Mol. Endocrinol. 1997, 11, 1747-1755.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 1747-1755
    • Endo, T.1    Kaneshige, M.2    Nakazato, M.3    Ohmori, M.4    Harri, N.5    Onaya, T.6
  • 34
    • 0032230345 scopus 로고    scopus 로고
    • A novel thyroid transcription factor is essential for thyrotropin induced upregulation of Na/I symporter gene expression
    • Ohmori, M.; Endo, T.; Harii, N.; Onaya, T. A novel thyroid transcription factor is essential for thyrotropin induced upregulation of Na/I symporter gene expression. Mol. Endocrinol. 1998, 12, 727-736.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 727-736
    • Ohmori, M.1    Endo, T.2    Harii, N.3    Onaya, T.4
  • 35
    • 0036226103 scopus 로고    scopus 로고
    • Characterization of a thyroid-specific and cyclic adenosine monophosphate-responsive enhancer far upstream from the human sodium iodide symporter gene
    • Schmitt, L. T.; Espinoza, C. R.; Loos, U. Characterization of a thyroid-specific and cyclic adenosine monophosphate-responsive enhancer far upstream from the human sodium iodide symporter gene. Thyroid 2002, 12, 273-278.
    • (2002) Thyroid , vol.12 , pp. 273-278
    • Schmitt, L.T.1    Espinoza, C.R.2    Loos, U.3
  • 36
    • 0026743033 scopus 로고
    • The thyrotropin receptor and the regulation of thyrocyte function and growth
    • Vassart, G.; Dumont, J. E. The thyrotropin receptor and the regulation of thyrocyte function and growth. Endocr. Rev. 1992, 13, 596-611.
    • (1992) Endocr. Rev. , vol.13 , pp. 596-611
    • Vassart, G.1    Dumont, J.E.2
  • 37
    • 0030006858 scopus 로고    scopus 로고
    • Increased cyclic adenosine 3',5'-monophosphate inhibits G protein-coupled activation of phospholipase C in rat FRTL-5 thyroid cells
    • Laglia, G.; Zeiger, M. A.; Leipricht, A.; Caturegli, P.; Levine, M. A.; Kohn, L. D.; Saji, M. Increased cyclic adenosine 3',5'-monophosphate inhibits G protein-coupled activation of phospholipase C in rat FRTL-5 thyroid cells. Endocrinology 1996, 137, 3170-3176.
    • (1996) Endocrinology , vol.137 , pp. 3170-3176
    • Laglia, G.1    Zeiger, M.A.2    Leipricht, A.3    Caturegli, P.4    Levine, M.A.5    Kohn, L.D.6    Saji, M.7
  • 38
    • 0030929220 scopus 로고    scopus 로고
    • Increased expression of the Na/I symporter in cultured human thyroid cells exposed to thyrotropin and in Graves' thyroid tissue
    • Saito, T.; Endo, T.; Kawaguchi, A.; Ikeda, M.; Nakazato, M.; Kogai, T.; Onaya, T. Increased expression of the Na/I symporter in cultured human thyroid cells exposed to thyrotropin and in Graves' thyroid tissue. J. Clin. Endocrinol. Metab. 1997, 82, 3331-3336.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 3331-3336
    • Saito, T.1    Endo, T.2    Kawaguchi, A.3    Ikeda, M.4    Nakazato, M.5    Kogai, T.6    Onaya, T.7
  • 39
    • 0030921147 scopus 로고    scopus 로고
    • Moderate doses of iodide in vivo inhibit cell proliferation and the expression of thyroperoxidase and Na//I symporter mRNAs in dog thyroid
    • Uyttersprot, N.; Pelgrims, N.; Carrasco, N.; Gervy, C.; Maenhaut, C.; Dumont, J. E.; Miot, F. Moderate doses of iodide in vivo inhibit cell proliferation and the expression of thyroperoxidase and Na//I symporter mRNAs in dog thyroid. Mol. Cell. Endocrinol. 1997, 131, 195-203.
    • (1997) Mol. Cell. Endocrinol. , vol.131 , pp. 195-203
    • Uyttersprot, N.1    Pelgrims, N.2    Carrasco, N.3    Gervy, C.4    Maenhaut, C.5    Dumont, J.E.6    Miot, F.7
  • 40
    • 0032575638 scopus 로고    scopus 로고
    • N-linked glycosylation of the thyroid Na+/I- Symporter (NIS). Implications for its secondary structure model
    • Levy, O.; De la Vieja, A.; Ginter, C. S.; Riedel, C.; Dai, G.; Carrasco, N. N-linked glycosylation of the thyroid Na+/I- symporter (NIS). Implications for its secondary structure model. J. Biol. Chem. 1998, 273, 22657-22663.
    • (1998) J. Biol. Chem. , vol.273 , pp. 22657-22663
    • Levy, O.1    De La Vieja, A.2    Ginter, C.S.3    Riedel, C.4    Dai, G.5    Carrasco, N.6
  • 41
    • 0035877782 scopus 로고    scopus 로고
    • Post-transcriptional regulation of the sodium/iodide symporter by thyrotropin
    • Riedel, C.; Levy, O.; Carrasco, N. Post-transcriptional regulation of the sodium/iodide symporter by thyrotropin. J. Biol. Chem. 2001, 276, 21458-21463.
    • (2001) J. Biol. Chem. , vol.276 , pp. 21458-21463
    • Riedel, C.1    Levy, O.2    Carrasco, N.3
  • 42
    • 0031010758 scopus 로고    scopus 로고
    • Regulation by thyroid-stimulating hormone of sodium/ iodide symporter gene expression and protein levels in FRTL-5 cells
    • Kogai, T.; Endo, T.; Saito, T.; Miyazaki, A.; Kawaguchi, A.; Onaya, T. Regulation by thyroid-stimulating hormone of sodium/ iodide symporter gene expression and protein levels in FRTL-5 cells. Endocrinology 1997, 138, 2227-2232.
    • (1997) Endocrinology , vol.138 , pp. 2227-2232
    • Kogai, T.1    Endo, T.2    Saito, T.3    Miyazaki, A.4    Kawaguchi, A.5    Onaya, T.6
  • 43
    • 0030793448 scopus 로고    scopus 로고
    • Characterization of the rat thyroid iodide transporter using anti-peptide antibodies
    • Paire, A.; Bernier-Valentin, F.; Selmi-Ruby, S.; Rousset, B. Characterization of the rat thyroid iodide transporter using anti-peptide antibodies. J. Biol. Chem. 1997, 272, 18245-18249.
    • (1997) J. Biol. Chem. , vol.272 , pp. 18245-18249
    • Paire, A.1    Bernier-Valentin, F.2    Selmi-Ruby, S.3    Rousset, B.4
  • 44
    • 1242341401 scopus 로고    scopus 로고
    • Advances in Na+/I- Symporter (NIS) research in the thyroid and beyond
    • Dohán, A.; Carrasco, N. Advances in Na+/I- symporter (NIS) research in the thyroid and beyond. Mol. Cell. Endocrinol. 2003, 213, 59-70.
    • (2003) Mol. Cell. Endocrinol. , vol.213 , pp. 59-70
    • Dohán, A.1    Carrasco, N.2
  • 45
    • 0033790427 scopus 로고    scopus 로고
    • Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake but not sodium/iodide symporter messenger RNA and protein expression
    • Kogai, T.; Curcio, F.; Hyman, S.; Cornford, E. M.; Brent, G. A.; Hershman, J. M. Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake but not sodium/iodide symporter messenger RNA and protein expression. J. Endocrinol. 2000, 167, 125-135.
    • (2000) J. Endocrinol. , vol.167 , pp. 125-135
    • Kogai, T.1    Curcio, F.2    Hyman, S.3    Cornford, E.M.4    Brent, G.A.5    Hershman, J.M.6
  • 46
    • 0028175767 scopus 로고
    • Na/I symporter activity is present in membrane vesicles from thyrotropin- Deprived non-I- transporting cultured thyroid cells
    • Kaminsky, S. M.; Levy, O.; Salvador, C.; Dai, G.; Carrasco, N. Na/I symporter activity is present in membrane vesicles from thyrotropin- deprived non-I- transporting cultured thyroid cells. Proc. Natl. Acad. Sci. USA 1994, 91, 3789-3793.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3789-3793
    • Kaminsky, S.M.1    Levy, O.2    Salvador, C.3    Dai, G.4    Carrasco, N.5
  • 47
    • 0032230340 scopus 로고    scopus 로고
    • Regulation of the rat thyrotropin receptor gene by the methylationsensitive transcription factor GA-binding protein
    • Yokomori, N.; Tawata, M.; Saito, T.; Shimura, H.; Onaya, T. Regulation of the rat thyrotropin receptor gene by the methylationsensitive transcription factor GA-binding protein. Mol. Endocrinol. 1998, 12, 1241-1249.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 1241-1249
    • Yokomori, N.1    Tawata, M.2    Saito, T.3    Shimura, H.4    Onaya, T.5
  • 48
    • 0033968255 scopus 로고    scopus 로고
    • Down-regulation by extracellular ATP of rat hepatocyte organic anion transport is mediated by serine phosphorylation of oatp1
    • Glavy, J. S.; Wu, S. M.; Wang, P. J.; Orr, G. A.; Wolkoff, A. W. Down-regulation by extracellular ATP of rat hepatocyte organic anion transport is mediated by serine phosphorylation of oatp1. J. Biol. Chem. 2000, 275, 1479-1484.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1479-1484
    • Glavy, J.S.1    Wu, S.M.2    Wang, P.J.3    Orr, G.A.4    Wolkoff, A.W.5
  • 49
  • 50
    • 0033618638 scopus 로고    scopus 로고
    • Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants
    • Ramamoorthy, S.; Blakely, R. D. Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants. Science 1999, 285, 763-766.
    • (1999) Science , vol.285 , pp. 763-766
    • Ramamoorthy, S.1    Blakely, R.D.2
  • 51
    • 0033922682 scopus 로고    scopus 로고
    • Molecular analysis of the sodium/iodide symporter: Impact on thyroid and extrathyroid pathophysiology
    • De la Vieja, A.; Dohán, O.; Levy, O.; Carrasco, N. Molecular analysis of the sodium/iodide symporter: impact on thyroid and extrathyroid pathophysiology. Physiol. Rev. 2000, 80, 1083-1095.
    • (2000) Physiol. Rev. , vol.80 , pp. 1083-1095
    • De La Vieja, A.1    Dohán, O.2    Levy, O.3    Carrasco, N.4
  • 53
    • 0033560065 scopus 로고    scopus 로고
    • PDZ domains: Fundamental building blocks in the organization of protein complexes at the plasma membrane
    • Fanning, A. S.; Anderson, J. M. PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane. J. Clin. Invest. 1999, 103, 767-772.
    • (1999) J. Clin. Invest. , vol.103 , pp. 767-772
    • Fanning, A.S.1    Anderson, J.M.2
  • 54
    • 0033522488 scopus 로고    scopus 로고
    • PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells
    • Perego, C.; Vanoni, C.; Villa, A.; Longhi, R.; Kaech, S. M.; Frohli, E.; Hajnal, A.; Kim, S. K.; Pietrini, G. PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells. EMBO J. 1999, 18, 2384-2393.
    • (1999) EMBO J. , vol.18 , pp. 2384-2393
    • Perego, C.1    Vanoni, C.2    Villa, A.3    Longhi, R.4    Kaech, S.M.5    Frohli, E.6    Hajnal, A.7    Kim, S.K.8    Pietrini, G.9
  • 55
    • 0031106781 scopus 로고    scopus 로고
    • Protein sorting by tyrosine-based signals: Adapting to the Ys and wherefores
    • Marks, M. S.; Ohno, H.; Kirchhausen, T.; Bonifacino, J. S. Protein sorting by tyrosine-based signals: adapting to the Ys and wherefores. Trends Cell Biol. 1997, 7, 124-128.
    • (1997) Trends Cell Biol. , vol.7 , pp. 124-128
    • Marks, M.S.1    Ohno, H.2    Kirchhausen, T.3    Bonifacino, J.S.4
  • 56
    • 0033515427 scopus 로고    scopus 로고
    • Nef-induced CD4 degradation: A diacidicbased motif in Nef functions as a lysosomal targeting signal through the binding of β-COP in endosomes
    • Piguet, V.; Gu, F.; Foti, M.; Demaurex, N.; Gruenberg, J.; Carpentier, J. L.; Trono, D. Nef-induced CD4 degradation: a diacidicbased motif in Nef functions as a lysosomal targeting signal through the binding of β-COP in endosomes. Cell 1999, 97, 63-73.
    • (1999) Cell , vol.97 , pp. 63-73
    • Piguet, V.1    Gu, F.2    Foti, M.3    Demaurex, N.4    Gruenberg, J.5    Carpentier, J.L.6    Trono, D.7
  • 57
    • 0028839910 scopus 로고
    • An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface
    • Voorhees, P.; Deignan, E.; Van Donselaar, E.; Humphrey, J.; Marks, M. S.; Peters, P. J.; Bonifacino, J. S. An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface. EMBO J. 1995, 14, 4961-4975.
    • (1995) EMBO J. , vol.14 , pp. 4961-4975
    • Voorhees, P.1    Deignan, E.2    Van Donselaar, E.3    Humphrey, J.4    Marks, M.S.5    Peters, P.J.6    Bonifacino, J.S.7
  • 58
    • 0035911961 scopus 로고    scopus 로고
    • An acidic motif retains vesicular monoamine transporter 2 on large dense core vesicles
    • Waites, C. L.; Mehta, A.; Tan, P. K.; Thomas, G.; Edwards, R. H.; Krantz, D. E. An acidic motif retains vesicular monoamine transporter 2 on large dense core vesicles. J. Cell Biol. 2001, 152, 1159-1168.
    • (2001) J. Cell Biol. , vol.152 , pp. 1159-1168
    • Waites, C.L.1    Mehta, A.2    Tan, P.K.3    Thomas, G.4    Edwards, R.H.5    Krantz, D.E.6
  • 59
    • 12644257060 scopus 로고
    • Radioactive iodine as an indicator in thyroid physiology. IV. the metabolism of iodine in Graves' disease
    • Hertz, S.; Roberts, A.; Salter, W. T. Radioactive iodine as an indicator in thyroid physiology. IV. The metabolism of iodine in Graves' disease. J. Clin. Invest. 1942, 21, 25-29.
    • (1942) J. Clin. Invest. , vol.21 , pp. 25-29
    • Hertz, S.1    Roberts, A.2    Salter, W.T.3
  • 60
    • 0033305355 scopus 로고    scopus 로고
    • Expression of the Na+/I- Symporter gene in human thyroid tumors: A comparison study with other thyroidspecific genes
    • Lazar, V.; Bidart, J-M.; Caillou, B.; Mahe, C.; Lacroix, L.; Filetti, S.; Schlumberger, M. Expression of the Na+/I- symporter gene in human thyroid tumors: a comparison study with other thyroidspecific genes. J. Clin. Endocrinol. Metab. 1999, 84, 3228-3234.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 3228-3234
    • Lazar, V.1    Bidart, J.-M.2    Caillou, B.3    Mahe, C.4    Lacroix, L.5    Filetti, S.6    Schlumberger, M.7
  • 62
    • 1642633596 scopus 로고    scopus 로고
    • Expression of human sodium iodide symporter mRNA in primary and metastatic papillary thyroid carcinomas
    • Park, H. -J.; Kim, J. Y.; Park, K. Y.; Gong, G.; Hong, S. J.; Ahn, I.-M. Expression of human sodium iodide symporter mRNA in primary and metastatic papillary thyroid carcinomas. Thyroid 2000, 10, 211-217.
    • (2000) Thyroid , vol.10 , pp. 211-217
    • Park, H.J.1    Kim, J.Y.2    Park, K.Y.3    Gong, G.4    Hong, S.J.5    Ahn, I.-M.6
  • 64
    • 0034971871 scopus 로고    scopus 로고
    • Rapid communication: Predominant intracellular overexpression of the Na(+)/I(-) symporter (NIS) in a large sampling of thyroid cancer cases
    • Dohán, O.; Baloch, Z.; Bánrévi, Z.; Livolsi, V.; Carrasco, N. Rapid communication: predominant intracellular overexpression of the Na(+)/I(-) symporter (NIS) in a large sampling of thyroid cancer cases. J. Clin. Endocrinol. Metab. 2001, 86, 2697-2700.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 2697-2700
    • Dohán, O.1    Baloch, Z.2    Bánrévi, Z.3    Livolsi, V.4    Carrasco, N.5
  • 65
    • 0000815028 scopus 로고
    • Plasma inorganic iodide as a homeostatic regulator of thyroid function
    • Wolff, J.; Chaikoff, I. L. Plasma inorganic iodide as a homeostatic regulator of thyroid function. J. Biol. Chem. 1948, 174, 555-564.
    • (1948) J. Biol. Chem. , vol.174 , pp. 555-564
    • Wolff, J.1    Chaikoff, I.L.2
  • 66
    • 0001720014 scopus 로고
    • The paradoxical effect of thiocyanate and of thyrotropin on the organic binding of iodine by the thyroid in the presence of large amounts of iodide
    • Raben, M. S. The paradoxical effect of thiocyanate and of thyrotropin on the organic binding of iodine by the thyroid in the presence of large amounts of iodide. Endocrinology 1949, 45, 296-304.
    • (1949) Endocrinology , vol.45 , pp. 296-304
    • Raben, M.S.1
  • 68
    • 0032819187 scopus 로고    scopus 로고
    • Regulation of sodium iodide symporter gene expression in FRTL-5 rat thyroid cells
    • Spitzweg, C.; Joba, W.; Morris, J. C.; Heufelder, A. E. Regulation of sodium iodide symporter gene expression in FRTL-5 rat thyroid cells. Thyroid 1999, 9, 821-830.
    • (1999) Thyroid , vol.9 , pp. 821-830
    • Spitzweg, C.1    Joba, W.2    Morris, J.C.3    Heufelder, A.E.4
  • 69
    • 0033305353 scopus 로고    scopus 로고
    • Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein
    • Eng, P. H. K.; Cardona, G. R.; Fang, S. L.; Previti, M.; Alex, S.; Carrasco, N.; Chin, W. W.; Braverman, L. E. Escape from the acute Wolff-Chaikoff effect is associated with a decrease in thyroid sodium/iodide symporter messenger ribonucleic acid and protein. Endocrinology 1999, 140, 3404-3410.
    • (1999) Endocrinology , vol.140 , pp. 3404-3410
    • Eng, P.H.K.1    Cardona, G.R.2    Fang, S.L.3    Previti, M.4    Alex, S.5    Carrasco, N.6    Chin, W.W.7    Braverman, L.E.8
  • 70
    • 0035118005 scopus 로고    scopus 로고
    • Regulation of the sodium iodide symporter by iodide in FRTL-5 cells. Eur
    • Eng, P. H. K.; Cardona, G. R.; Previti, M. C.; Chin, W. W.; Braverman, L. E. Regulation of the sodium iodide symporter by iodide in FRTL-5 cells. Eur. J. Endocrinol. 2001, 144, 139-144.
    • (2001) J. Endocrinol. , vol.144 , pp. 139-144
    • Eng, P.H.K.1    Cardona, G.R.2    Previti, M.C.3    Chin, W.W.4    Braverman, L.E.5
  • 72
    • 0028152879 scopus 로고
    • Influence of tumor necrosis factor- α (TNF-α), tumor necrosis factor- β and interferon- γ, separately and added together with interleukin-1β, on the function of cultured human thyroid cells
    • Rasmussen, A. K.; Kayser, L.; Feldt-Rasmussen, U. Influence of tumor necrosis factor- α (TNF-α), tumor necrosis factor- β and interferon- γ, separately and added together with interleukin-1β, on the function of cultured human thyroid cells. J. Endocrinol. 1994, 143, 359-365.
    • (1994) J. Endocrinol. , vol.143 , pp. 359-365
    • Rasmussen, A.K.1    Kayser, L.2    Feldt-Rasmussen, U.3
  • 74
    • 0027548295 scopus 로고
    • The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line
    • Santoro, M.; Melillo, R. M.; Grieco, M.; Berlingieri, M. T.; Vecchio, G.; Fusco, A. The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line. Cell Growth Differ. 1993, 4, 77-84.
    • (1993) Cell Growth Differ. , vol.4 , pp. 77-84
    • Santoro, M.1    Melillo, R.M.2    Grieco, M.3    Berlingieri, M.T.4    Vecchio, G.5    Fusco, A.6
  • 75
    • 0242406737 scopus 로고    scopus 로고
    • Acute expression of RET/PTC induces isozyme-specific activation and subsequent downregulation of PKCepsilon in PCCL3 thyroid cells
    • Knauf, J. A.; Ouyang, B.; Croyle, M.; Kimura, E.; Fagin, J. A. Acute expression of RET/PTC induces isozyme-specific activation and subsequent downregulation of PKCepsilon in PCCL3 thyroid cells. Oncogene 2003, 22, 6830-6838.
    • (2003) Oncogene , vol.22 , pp. 6830-6838
    • Knauf, J.A.1    Ouyang, B.2    Croyle, M.3    Kimura, E.4    Fagin, J.A.5
  • 76
    • 16844367605 scopus 로고    scopus 로고
    • Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells
    • Mitsutake, N.; Knauf, J. A.; Mitsutake, S.; Mesa, C., Jr.; Zhang, L.; Fagin, J. A. Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells. Cancer Res. 2005, 65, 2465-2473.
    • (2005) Cancer Res. , vol.65 , pp. 2465-2473
    • Mitsutake, N.1    Knauf, J.A.2    Mitsutake, S.3    Mesa Jr., C.4    Zhang, L.5    Fagin, J.A.6
  • 78
    • 0031587387 scopus 로고    scopus 로고
    • Retinoic acid increases sodium/iodide symporter mRNA levels in human thyroid cancer cell lines and suppresses expression of functional symporter in nontransformed FRTL-5 rat thyroid cells
    • Schmutzler, C.; Winzer, R.; Meissner-Weigl, J.; Kohrle, J. Retinoic acid increases sodium/iodide symporter mRNA levels in human thyroid cancer cell lines and suppresses expression of functional symporter in nontransformed FRTL-5 rat thyroid cells. Biochem. Biophys. Res. Commun. 1997, 240, 832-838.
    • (1997) Biochem. Biophys. Res. Commun. , vol.240 , pp. 832-838
    • Schmutzler, C.1    Winzer, R.2    Meissner-Weigl, J.3    Kohrle, J.4
  • 79
    • 33749430081 scopus 로고    scopus 로고
    • Effect of all-trans retinoic acid on sodium/iodide symporter expression, radioiodine uptake and gene expression profiles in a human anaplastic thyroid carcinoma cell line
    • Jeong, H.; Kim, Y. R.; Kim, K. N.; Choe, J. G.; Chung, J. K.; Kim, M. K. Effect of all-trans retinoic acid on sodium/iodide symporter expression, radioiodine uptake and gene expression profiles in a human anaplastic thyroid carcinoma cell line. Nucl. Med. Biol. 2006, 33, 875-882.
    • (2006) Nucl. Med. Biol. , vol.33 , pp. 875-882
    • Jeong, H.1    Kim, Y.R.2    Kim, K.N.3    Choe, J.G.4    Chung, J.K.5    Kim, M.K.6
  • 83
    • 20144367845 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell lines
    • Park, J. W.; Zarnegar, R.; Kanauchi, H.; Wong, M. G.; Hyun, W. C.; Ginzinger, D. G.; Lobo, M.; Cotter, P.; Duh, Q. Y.; Clark, O. H. Troglitazone, the peroxisome proliferator-activated receptor-gamma agonist, induces antiproliferation and redifferentiation in human thyroid cancer cell lines. Thyroid 2005, 15, 222-231.
    • (2005) Thyroid , vol.15 , pp. 222-231
    • Park, J.W.1    Zarnegar, R.2    Kanauchi, H.3    Wong, M.G.4    Hyun, W.C.5    Ginzinger, D.G.6    Lobo, M.7    Cotter, P.8    Duh, Q.Y.9    Troglitazone, C.O.H.10
  • 84
    • 0035019640 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells
    • Ohta, K.; Endo, T.; Haraguchi, K.; Hershman, J. M.; Onaya, T. Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells. J. Clin. Endocrinol. Metab. 2001, 86, 2170-2177.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 2170-2177
    • Ohta, K.1    Endo, T.2    Haraguchi, K.3    Hershman, J.M.4    Onaya, T.5
  • 86
    • 0034913856 scopus 로고    scopus 로고
    • Low concentrations of the histone deacetylase inhibitor, depsipeptide (FR901228), increase expression of the NaC/IK symporter and iodine accumulation in poorly differentiated thyroid carcinoma cells
    • Kitazono, M.; Robey, R.; Zhan, Z.; Sarlis, N. J.; Skarulis, M. C.; Aikou, T.; Bates, S.; Fojo, T. Low concentrations of the histone deacetylase inhibitor, depsipeptide (FR901228), increase expression of the NaC/IK symporter and iodine accumulation in poorly differentiated thyroid carcinoma cells. J. Clin. Endocrinol. Metab. 2001, 86, 3430-3435.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 3430-3435
    • Kitazono, M.1    Robey, R.2    Zhan, Z.3    Sarlis, N.J.4    Skarulis, M.C.5    Aikou, T.6    Bates, S.7    Fojo, T.8
  • 87
    • 2542458413 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/ iodide symporter thyroperoxidase and thyroglobulin
    • Furuya, F.; Shimura, H.; Suzuki, H.; Taki, K.; Ohta, K.; Haraguchi, K.; Onaya, T.; Endo, T.; Kobayashi, T. Histone deacetylase inhibitors restore radioiodide uptake and retention in poorly differentiated and anaplastic thyroid cancer cells by expression of the sodium/ iodide symporter thyroperoxidase and thyroglobulin. Endocrinology 2004, 145, 2865-2875.
    • (2004) Endocrinology , vol.145 , pp. 2865-2875
    • Furuya, F.1    Shimura, H.2    Suzuki, H.3    Taki, K.4    Ohta, K.5    Haraguchi, K.6    Onaya, T.7    Endo, T.8    Kobayashi, T.9
  • 88
    • 1442352159 scopus 로고    scopus 로고
    • Valproic acid induces the expression of the NaC/IK symporter and iodine uptake in poorly differentiated thyroid cancer cells
    • Fortunati, N.; Catalano, M. G.; Arena, K.; Brignardello, E.; Piovesan, A.; Boccuzzi, G. Valproic acid induces the expression of the NaC/IK symporter and iodine uptake in poorly differentiated thyroid cancer cells. J. Clin. Endocrinol. Metab. 2004, 89, 1006-1009.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 1006-1009
    • Fortunati, N.1    Catalano, M.G.2    Arena, K.3    Brignardello, E.4    Piovesan, A.5    Boccuzzi, G.6
  • 89
    • 29144445219 scopus 로고    scopus 로고
    • Valproic acid inhibits growth, induces apoptosis, and modulates apoptosis-regulatory and differentiation gene expression in human thyroid cancer cells
    • Shen, W. T.; Wong, T. S.; Chung, W. Y.; Wong, M. G.; Kebebew, E.; Duh, Q. Y.; Clark, O. H. Valproic acid inhibits growth, induces apoptosis, and modulates apoptosis-regulatory and differentiation gene expression in human thyroid cancer cells. Surgery 2005, 138, 979-985.
    • (2005) Surgery , vol.138 , pp. 979-985
    • Shen, W.T.1    Wong, T.S.2    Chung, W.Y.3    Wong, M.G.4    Kebebew, E.5    Duh, Q.Y.6    Clark, O.H.7
  • 90
    • 0030846298 scopus 로고    scopus 로고
    • Tying it all together: Epigenetics, genetics, cell cycle, and cancer
    • Baylin, S. B. Tying it all together: epigenetics, genetics, cell cycle, and cancer. Science 1997, 277, 1948-1949.
    • (1997) Science , vol.277 , pp. 1948-1949
    • Baylin, S.B.1
  • 91
    • 0033306106 scopus 로고    scopus 로고
    • Restoration of iodide uptake in dedifferentiated thyroid carcinoma: Relationship to human Na+/I- Symporter gene methylation status
    • Venkataraman, G. M.; Yatin, M.; Marcinek, R.; Ain, K. B. Restoration of iodide uptake in dedifferentiated thyroid carcinoma: relationship to human Na+/I- symporter gene methylation status. J. Clin. Endocrinol. Metab. 1999, 84, 2449-2457.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 2449-2457
    • Venkataraman, G.M.1    Yatin, M.2    Marcinek, R.3    Ain, K.B.4
  • 92
    • 1642411997 scopus 로고    scopus 로고
    • Lack of correlation for sodium iodide symporter mRNA and protein expression and analysis of sodium iodide symporter promoter methylation in benign cold thyroid nodules
    • Neumann, S.; Schuchardt, K.; Reske, A.; Emmrich, P.; Paschke, R. Lack of correlation for sodium iodide symporter mRNA and protein expression and analysis of sodium iodide symporter promoter methylation in benign cold thyroid nodules. Thyroid 2004, 14, 99-111.
    • (2004) Thyroid , vol.14 , pp. 99-111
    • Neumann, S.1    Schuchardt, K.2    Reske, A.3    Emmrich, P.4    Paschke, R.5
  • 93
    • 0033609861 scopus 로고    scopus 로고
    • Follicular thyroglobulin (TG) suppression of thyroid-restricted genes involves the apical membrane asialoglycoprotein receptor and TG phosphorylation
    • Ulianich, L.; Suzuki, K.; Mori, A.; Nakazato, M.; Pietrarelli, M.; Goldsmith, P.; Pacifico, F.; Consiglio, E.; Formisano, S.; Kohn, L. D. Follicular thyroglobulin (TG) suppression of thyroid-restricted genes involves the apical membrane asialoglycoprotein receptor and TG phosphorylation. J. Biol. Chem. 1999, 274, 25099-25107.
    • (1999) J. Biol. Chem. , vol.274 , pp. 25099-25107
    • Ulianich, L.1    Suzuki, K.2    Mori, A.3    Nakazato, M.4    Pietrarelli, M.5    Goldsmith, P.6    Pacifico, F.7    Consiglio, E.8    Formisano, S.9    Kohn, L.D.10
  • 94
    • 0033305105 scopus 로고    scopus 로고
    • Estradiol increases proliferation and down-regulates the sodium/iodide symporter gene in FRTL-5 cells
    • Furlanetto, T. W.; Nguyen, L. Q.; Jameson, J. L. Estradiol increases proliferation and down-regulates the sodium/iodide symporter gene in FRTL-5 cells. Endocrinology 1999, 140, 5705-5711.
    • (1999) Endocrinology , vol.140 , pp. 5705-5711
    • Furlanetto, T.W.1    Nguyen, L.Q.2    Jameson, J.L.3
  • 95
    • 0001468731 scopus 로고
    • Extra-thyroidal iodide concentrating mechanisms
    • Brown-Grant, K. Extra-thyroidal iodide concentrating mechanisms. Physiol. Rev. 1961, 41, 189-213.
    • (1961) Physiol. Rev. , vol.41 , pp. 189-213
    • Brown-Grant, K.1
  • 96
    • 0027288003 scopus 로고
    • Iodide transport in the thyroid gland
    • Carrasco, N. Iodide transport in the thyroid gland. Biochim. Biophys. Acta 1993, 1154, 65-82.
    • (1993) Biochim. Biophys. Acta , vol.1154 , pp. 65-82
    • Carrasco, N.1
  • 97
    • 0000138799 scopus 로고
    • Thyroidal iodide transport
    • Halmi, N. S. Thyroidal iodide transport. Vitam. Horm. 1961, 19, 133-163.
    • (1961) Vitam. Horm. , vol.19 , pp. 133-163
    • Halmi, N.S.1
  • 99
    • 0031723728 scopus 로고    scopus 로고
    • Analysis of human sodium iodide symporter gene expression in extrathyroidal tissues and cloning of its complementary DNA from salivary gland, mammary gland, and gastric mucosa
    • Spitzweg, C.; Joba, W.; Eisenmenger, W.; Heufelder, A. E. Analysis of human sodium iodide symporter gene expression in extrathyroidal tissues and cloning of its complementary DNA from salivary gland, mammary gland, and gastric mucosa. J. Clin. Endocrinol. Metab. 1998, 83, 1746-1751.
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 1746-1751
    • Spitzweg, C.1    Joba, W.2    Eisenmenger, W.3    Heufelder, A.E.4
  • 102
    • 0016248790 scopus 로고
    • Comparison of lactoperoxidase- and thyroid peroxidase-catalyzed iodination and coupling
    • Taurog, A.; Dorris, M. L.; Lamas, L. Comparison of lactoperoxidase- and thyroid peroxidase-catalyzed iodination and coupling. Endocrinology 1974, 94, 1286-1294.
    • (1974) Endocrinology , vol.94 , pp. 1286-1294
    • Taurog, A.1    Dorris, M.L.2    Lamas, L.3
  • 104
    • 0033711863 scopus 로고    scopus 로고
    • Effect of prolactin on sodium iodide symporter expression in mouse mammary gland explants
    • Rillema, J. A.; Yu, T. X.; Jhiang, S. M. Effect of prolactin on sodium iodide symporter expression in mouse mammary gland explants. Am. J. Physiol. Endocrinol. Metab. 2000, 279, E769-E772.
    • (2000) Am. J. Physiol. Endocrinol. Metab. , vol.279
    • Rillema, J.A.1    Yu, T.X.2    Jhiang, S.M.3
  • 107
    • 0037683589 scopus 로고    scopus 로고
    • Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections
    • Wapnir, I. L.; van de Rijn, M.; Nowels, K.; Amenta, P. S.; Walton, K.; Montgomery, K.; Greco, R. S.; Dohan, O.; Carrasco, N. Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections. J. Clin. Endocrinol. Metab. 2003, 88, 1880-1888.
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 1880-1888
    • Wapnir, I.L.1    Van De Rijn, M.2    Nowels, K.3    Amenta, P.S.4    Walton, K.5    Montgomery, K.6    Greco, R.S.7    Dohan, O.8    Carrasco, N.9
  • 108
    • 0035487238 scopus 로고    scopus 로고
    • Correlation between 99mTc-pertechnetate uptake and expression of human sodium iodide symporter gene in breast tumor tissues
    • Moon, D. H.; Lee, S. J.; Park, K. Y.; Park, K. K.; Ahn, S. H.; Pai, M. S.; Chang, H.; Lee, H. K.; Ahn, I.M. Correlation between 99mTc-pertechnetate uptake and expression of human sodium iodide symporter gene in breast tumor tissues. Nucl. Med. Biol. 2001, 28, 829-834.
    • (2001) Nucl. Med. Biol. , vol.28 , pp. 829-834
    • Moon, D.H.1    Lee, S.J.2    Park, K.Y.3    Park, K.K.4    Ahn, S.H.5    Pai, M.S.6    Chang, H.7    Lee, H.K.8    Ahn, I.M.9
  • 109
    • 3042811612 scopus 로고    scopus 로고
    • The Na+/I- Symporter mediates iodide uptake in breast cancer metastases and can be selectively downregulated in the thyroid
    • Wapnir, I. L.; Goris, M.; Yudd, A.; Dohan, O.; Adelman, D.; Nowels, K.; Carrasco, N. The Na+/I- symporter mediates iodide uptake in breast cancer metastases and can be selectively downregulated in the thyroid. Clin. Cancer Res. 2004, 10, 4294-4302.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 4294-4302
    • Wapnir, I.L.1    Goris, M.2    Yudd, A.3    Dohan, O.4    Adelman, D.5    Nowels, K.6    Carrasco, N.7
  • 110
    • 34548389433 scopus 로고    scopus 로고
    • PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer
    • Knostman, K. A.; McCubrey, J. A.; Morrison, C. D.; Zhang, Z.; Capen, C. C.; Jhiang, S. M. PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer. BMC Cancer 2007, 7, 137.
    • (2007) BMC Cancer , vol.7 , pp. 137
    • Knostman, K.A.1    McCubrey, J.A.2    Morrison, C.D.3    Zhang, Z.4    Capen, C.C.5    Jhiang, S.M.6
  • 111
    • 0034682497 scopus 로고    scopus 로고
    • Retinoic acid induces sodium/iodide symporter gene expression and radioiodide uptake in the MCF-7 breast cancer cell line
    • Kogai, T.; Schultz, J. J.; Johnson, L. S.; Huang, M.; Brent, G. A. Retinoic acid induces sodium/iodide symporter gene expression and radioiodide uptake in the MCF-7 breast cancer cell line. Proc. Natl. Acad. Sci. USA 2000, 97, 8519-8524.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8519-8524
    • Kogai, T.1    Schultz, J.J.2    Johnson, L.S.3    Huang, M.4    Brent, G.A.5
  • 112
    • 22144497430 scopus 로고    scopus 로고
    • Differential regulation of sodium/iodide symporter (NIS) gene expression by nuclear receptor ligands in MCF-7 breast cancer cells
    • Kogai, T.; Kanamoto, Y.; Li, A. I.; Che, L. H.; Ohashi, E.; Taki, K.; Chandraratna, R. A.; Saito, T.; Brent, G. A. Differential regulation of sodium/iodide symporter (NIS) gene expression by nuclear receptor ligands in MCF-7 breast cancer cells. Endocrinology 2005, 146, 3059-3069.
    • (2005) Endocrinology , vol.146 , pp. 3059-3069
    • Kogai, T.1    Kanamoto, Y.2    Li, A.I.3    Che, L.H.4    Ohashi, E.5    Taki, K.6    Chandraratna, R.A.7    Saito, T.8    Brent, G.A.9
  • 113
    • 0037899647 scopus 로고    scopus 로고
    • Effect of ligands of nuclear hormone receptors on sodium/iodide symporter expression and activity in breast cancer cells
    • Tanosaki, S.; Ikezoe, T.; Heaney, A.; Said, J. W.; Dan, K.; Akashi, M.; Koeffler, H. P. Effect of ligands of nuclear hormone receptors on sodium/iodide symporter expression and activity in breast cancer cells. Breast Cancer Res. Treat. 2003, 79, 335-345.
    • (2003) Breast Cancer Res. Treat. , vol.79 , pp. 335-345
    • Tanosaki, S.1    Ikezoe, T.2    Heaney, A.3    Said, J.W.4    Dan, K.5    Akashi, M.6    Koeffler, H.P.7
  • 114
    • 1642576178 scopus 로고    scopus 로고
    • Systemic retinoic acid treatment induces sodium/iodide symporter expression and radioiodide uptake in mouse breast cancer models
    • Kogai, T.; Kanamoto, Y.; Che, L. H.; Taki, K.; Moatamed, F.; Schultz, J. J.; Brent, G. A. Systemic retinoic acid treatment induces sodium/iodide symporter expression and radioiodide uptake in mouse breast cancer models. Cancer Res. 2004, 64, 415-422.
    • (2004) Cancer Res. , vol.64 , pp. 415-422
    • Kogai, T.1    Kanamoto, Y.2    Che, L.H.3    Taki, K.4    Moatamed, F.5    Schultz, J.J.6    Brent, G.A.7
  • 115
    • 15844384344 scopus 로고    scopus 로고
    • AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells
    • Agarwal, C.; Chandraratna, R. A.; Johnson, A. T.; Rorke, E. A.; Eckert, R. L. AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells. J. Biol. Chem. 1996, 271, 12209-12212.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12209-12212
    • Agarwal, C.1    Chandraratna, R.A.2    Johnson, A.T.3    Rorke, E.A.4    Eckert, R.L.5
  • 116
    • 0034760429 scopus 로고    scopus 로고
    • Cellular metabolism and actions of 13-cis retinoic acid
    • Blaner, W. S. Cellular metabolism and actions of 13-cis retinoic acid. J. Am. Acad. Dermatol. 2001, 45, S129-S135.
    • (2001) J. Am. Acad. Dermatol. , vol.45
    • Blaner, W.S.1
  • 117
    • 0037367225 scopus 로고    scopus 로고
    • The modified firefly luciferase reporter gene (lucC) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells
    • Kogai, T.; Kanamoto, Y.; Brent, G. A. The modified firefly luciferase reporter gene (lucC) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells. Breast Cancer Res. Treat. 2003, 78, 119-126.
    • (2003) Breast Cancer Res. Treat. , vol.78 , pp. 119-126
    • Kogai, T.1    Kanamoto, Y.2    Brent, G.A.3
  • 118
    • 4444237908 scopus 로고    scopus 로고
    • Transcription factor Nkx-2.5 induces sodium/iodide symporter gene expression and participates in retinoic acid- and lactation-induced transcription in mammary cells
    • Dentice, M.; Luongo, C.; Elefante, A.; Romino, R.; Ambrosio, R.; Vitale, M.; Rossi, G.; Fenzi, G.; Salvatore, D. Transcription factor Nkx-2.5 induces sodium/iodide symporter gene expression and participates in retinoic acid- and lactation-induced transcription in mammary cells. Mol. Cell. Biol. 2004, 24, 7863-7877.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7863-7877
    • Dentice, M.1    Luongo, C.2    Elefante, A.3    Romino, R.4    Ambrosio, R.5    Vitale, M.6    Rossi, G.7    Fenzi, G.8    Salvatore, D.9
  • 119
    • 33751088303 scopus 로고    scopus 로고
    • Enhancement of sodium/iodide symporter expression in thyroid and breast cancer
    • Kogai, T.; Taki, K.; Brent, G. A. Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. Endocr. Relat. Cancer 2006, 13, 797-826.
    • (2006) Endocr. Relat. Cancer , vol.13 , pp. 797-826
    • Kogai, T.1    Taki, K.2    Brent, G.A.3
  • 120
    • 30344472693 scopus 로고    scopus 로고
    • Dexamethasone stimulation of retinoic Acid-induced sodium iodide symporter expression and cytotoxicity of 131-I in breast cancer cells
    • Unterholzner, S.; Willhauck, M. J.; Cengic, N.; Schütz, M.; Göke, B.; Morris, J. C.; Spitzweg, C. Dexamethasone stimulation of retinoic Acid-induced sodium iodide symporter expression and cytotoxicity of 131-I in breast cancer cells. J. Clin. Endocrinol. Metab. 2006, 91, 69-78.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 69-78
    • Unterholzner, S.1    Willhauck, M.J.2    Cengic, N.3    Schütz, M.4    Göke, B.5    Morris, J.C.6    Spitzweg, C.7
  • 122
    • 10644236455 scopus 로고    scopus 로고
    • The palliative role of 131I-MIBG and 111-In-octreotide therapy in patients with metastatic progressive neuroendocrine neoplasms
    • Pasieka, J. L.; McEwan, A. J.; Rorstad, O. The palliative role of 131I-MIBG and 111-In-octreotide therapy in patients with metastatic progressive neuroendocrine neoplasms. Surgery 2004, 136, 1218-1226.
    • (2004) Surgery , vol.136 , pp. 1218-1226
    • Pasieka, J.L.1    McEwan, A.J.2    Rorstad, O.3
  • 123
    • 34447545672 scopus 로고    scopus 로고
    • A comparative study of 188Re-HEDP, 186Re-HEDP, 153Sm-EDTMP and 89Sr in the treatment of painful skeletal metastases
    • Liepe, K.; Kotzerke, J. A comparative study of 188Re-HEDP, 186Re-HEDP, 153Sm-EDTMP and 89Sr in the treatment of painful skeletal metastases. Nucl. Med. Commun. 2007, 28, 623-630.
    • (2007) Nucl. Med. Commun. , vol.28 , pp. 623-630
    • Liepe, K.1    Kotzerke, J.2
  • 124
    • 34347204847 scopus 로고    scopus 로고
    • Radium-223 for men with hormonerefractory prostate cancer and bone metastases
    • Shelley, M. D.; Mason, M. D. Radium-223 for men with hormonerefractory prostate cancer and bone metastases. Lancet Oncol. 2007, 8, 564-567.
    • (2007) Lancet Oncol. , vol.8 , pp. 564-567
    • Shelley, M.D.1    Mason, M.D.2
  • 125
    • 60549088714 scopus 로고    scopus 로고
    • Radiolabeled metaiodobenzylguanidine for imaging and therapy of neuroblastoma
    • Taggart, D.; Dubois, S.; Matthay, K. K. Radiolabeled metaiodobenzylguanidine for imaging and therapy of neuroblastoma. Q. J. Nucl. Med. Mol. Imaging 2008, 52, 403-418.
    • (2008) Q. J. Nucl. Med. Mol. Imaging , vol.52 , pp. 403-418
    • Taggart, D.1    Dubois, S.2    Matthay, K.K.3
  • 127
    • 0033135063 scopus 로고    scopus 로고
    • Prostate specific antigen (PSA) promoter-driven androgen-inducible expression of sodium iodide symporter in prostate cancer cell lines
    • Spitzweg, C.; Zhang, S.; Bergert, E. R.; Castro, M. R.; McIver, B.; Heufelder, A. E.; Tindall, D. J.; Young, C. Y.; Morris, J. C. Prostate specific antigen (PSA) promoter-driven androgen-inducible expression of sodium iodide symporter in prostate cancer cell lines. Cancer Res. 1999, 59, 2136-2141.
    • (1999) Cancer Res. , vol.59 , pp. 2136-2141
    • Spitzweg, C.1    Zhang, S.2    Bergert, E.R.3    Castro, M.R.4    McIver, B.5    Heufelder, A.E.6    Tindall, D.J.7    Young, C.Y.8    Morris, J.C.9
  • 128
    • 0033693586 scopus 로고    scopus 로고
    • Treatment of prostate cancer by radioiodine therapy after tissue-specific expression of the sodium iodide symporter
    • Spitzweg, C.; O'Connor, M. K.; Bergert, E. R.; Tindall, D. J.; Young, C. Y.; Morris, J. C. Treatment of prostate cancer by radioiodine therapy after tissue-specific expression of the sodium iodide symporter. Cancer Res. 2000, 15, 6526-6530.
    • (2000) Cancer Res. , vol.15 , pp. 6526-6530
    • Spitzweg, C.1    O'Connor, M.K.2    Bergert, E.R.3    Tindall, D.J.4    Young, C.Y.5    Morris, J.C.6
  • 130
    • 1042278763 scopus 로고    scopus 로고
    • Radiation-induced bystander effects-implications for cancer
    • Mothersill, C.; Seymour, C. B. Radiation-induced bystander effects-implications for cancer. Nat. Rev. Cancer 2004, 4, 158-164.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 158-164
    • Mothersill, C.1    Seymour, C.B.2
  • 131
    • 0036023755 scopus 로고    scopus 로고
    • Bystander effects: Intercellular transmission of radiation damage signals
    • Little, J. B.; Azzam, E. I.; De Toledo, S. M.; Nagasawa, H. Bystander effects: intercellular transmission of radiation damage signals. Radiat. Prot. Dosimet. 2002, 99, 159-162.
    • (2002) Radiat. Prot. Dosimet. , vol.99 , pp. 159-162
    • Little, J.B.1    Azzam, E.I.2    De Toledo, S.M.3    Nagasawa, H.4
  • 132
    • 0030955364 scopus 로고    scopus 로고
    • Iodide uptake and experimental 131I therapy in transplanted undifferentiated thyroid cancer cells expressing the Na+/I- Symporter gene
    • Shimura, H.; Haraguchi, K.; Myazaki, A.; Endo, T.; Onaya, T. Iodide uptake and experimental 131I therapy in transplanted undifferentiated thyroid cancer cells expressing the Na+/I- symporter gene. Endocrinology 1997, 138, 4493-4496.
    • (1997) Endocrinology , vol.138 , pp. 4493-4496
    • Shimura, H.1    Haraguchi, K.2    Myazaki, A.3    Endo, T.4    Onaya, T.5
  • 133
    • 33750269612 scopus 로고    scopus 로고
    • A perspective view of sodium iodide symporter research and its clinical implications
    • Riesco-Eizaguirre, G.; Santisteban, P. A perspective view of sodium iodide symporter research and its clinical implications. Eur. J. Endocrinol. 2006, 155, 495-512.
    • (2006) Eur. J. Endocrinol. , vol.155 , pp. 495-512
    • Riesco-Eizaguirre, G.1    Santisteban, P.2
  • 134
    • 0034114693 scopus 로고    scopus 로고
    • Expression and activity of human Na1/I2 symporter in human glioma cells by adenovirus-mediated gene delivery
    • Cho, J. -Y.; Xing, S.; Liu, X.; Buckwalter, T. L.; Hwa, L.; Sferra, T. J.; Chiu, I. M.; Jhiang, S. M. Expression and activity of human Na1/I2 symporter in human glioma cells by adenovirus-mediated gene delivery. Gene Ther. 2000, 7, 740-749.
    • (2000) Gene Ther. , vol.7 , pp. 740-749
    • Cho, J.Y.1    Xing, S.2    Liu, X.3    Buckwalter, T.L.4    Hwa, L.5    Sferra, T.J.6    Chiu, I.M.7    Jhiang, S.M.8
  • 135
    • 0033083046 scopus 로고    scopus 로고
    • Radioisotope concentrator gene therapy using the sodium/iodide symporter gene
    • Mandell, R. B.; Mandell, L. Z.; Link, C. J. Radioisotope concentrator gene therapy using the sodium/iodide symporter gene. Cancer Res. 1999, 59, 661-668.
    • (1999) Cancer Res. , vol.59 , pp. 661-668
    • Mandell, R.B.1    Mandell, L.Z.2    Link, C.J.3
  • 136
    • 0034234255 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of the thyroid sodium/iodide symporter gene into tumors for a targeted radiotherapy
    • Boland, A.; Ricard, M.; Opolon, P.; Bidart, J. M.; Yeh, P.; Filetti, S.; Schlumberger, M.; Perricaudet, M. Adenovirus-mediated transfer of the thyroid sodium/iodide symporter gene into tumors for a targeted radiotherapy. Cancer Res. 2000, 60, 3484-3492.
    • (2000) Cancer Res. , vol.60 , pp. 3484-3492
    • Boland, A.1    Ricard, M.2    Opolon, P.3    Bidart, J.M.4    Yeh, P.5    Filetti, S.6    Schlumberger, M.7    Perricaudet, M.8
  • 137
    • 0033763427 scopus 로고    scopus 로고
    • Establishment and characterization of a breast cancer cell line expressing Na+/I- Symporters for radioiodide concentrator gene therapy
    • Nakamoto, Y.; Saga, T.; Misaki, T.; Kobayashi, H.; Sato, N.; Ishimori, T.; Kosugi, S.; Sakahara, H.; Konishi, J. Establishment and characterization of a breast cancer cell line expressing Na+/I- symporters for radioiodide concentrator gene therapy. J. Nucl. Med. 2000, 41, 1898-1904.
    • (2000) J. Nucl. Med. , vol.41 , pp. 1898-1904
    • Nakamoto, Y.1    Saga, T.2    Misaki, T.3    Kobayashi, H.4    Sato, N.5    Ishimori, T.6    Kosugi, S.7    Sakahara, H.8    Konishi, J.9
  • 139
    • 0345707573 scopus 로고    scopus 로고
    • Probasin promoter (ARR(2)PB)-driven, prostate-specific expression of the human sodium iodide symporter (h-NIS) for targeted radioiodine therapy of prostate cancer
    • Kakinuma, H.; Bergert, E. R.; Spitzweg, C.; Cheville, J. C.; Lieber, M. M.; Morris, J. C. Probasin promoter (ARR(2)PB)-driven, prostate-specific expression of the human sodium iodide symporter (h-NIS) for targeted radioiodine therapy of prostate cancer. Cancer Res. 2003, 63, 7840-7844.
    • (2003) Cancer Res. , vol.63 , pp. 7840-7844
    • Kakinuma, H.1    Bergert, E.R.2    Spitzweg, C.3    Cheville, J.C.4    Lieber, M.M.5    Morris, J.C.6
  • 140
    • 0037569486 scopus 로고    scopus 로고
    • Tumour-specific activation of the sodium/ iodide symporter gene under control of the glucose transporter gene 1 promoter (GTI-1.3)
    • Sieger, S.; Jiang, S.; Schönsiegel, F.; Eskerski, H.; Kübler, W.; Altmann, A.; Haberkorn, U. Tumour-specific activation of the sodium/ iodide symporter gene under control of the glucose transporter gene 1 promoter (GTI-1.3). Eur. J. Nucl. Med. Mol. Imaging 2003, 30, 748-756.
    • (2003) Eur. J. Nucl. Med. Mol. Imaging , vol.30 , pp. 748-756
    • Sieger, S.1    Jiang, S.2    Schönsiegel, F.3    Eskerski, H.4    Kübler, W.5    Altmann, A.6    Haberkorn, U.7
  • 141
    • 0037766148 scopus 로고    scopus 로고
    • Enhanced iodide transport after transfer of the human sodium iodide symporter gene is associated with lack of retention and low absorbed dose
    • Haberkorn, U.; Kinscherf, R.; Kissel, M.; Kübler, W.; Mahmut, M.; Sieger, S.; Eisenhut, M.; Peschke, P.; Altmann, A. Enhanced iodide transport after transfer of the human sodium iodide symporter gene is associated with lack of retention and low absorbed dose. Gene Ther. 2003, 10, 774-780.
    • (2003) Gene Ther. , vol.10 , pp. 774-780
    • Haberkorn, U.1    Kinscherf, R.2    Kissel, M.3    Kübler, W.4    Mahmut, M.5    Sieger, S.6    Eisenhut, M.7    Peschke, P.8    Altmann, A.9
  • 142
  • 143
    • 1442325309 scopus 로고    scopus 로고
    • Genetically targeted radiotherapy of head and neck squamous cell carcinoma using the sodium-iodide symporter (NIS)
    • Gaut, A. W.; Niu, G.; Krager, K. J.; Graham, M. M.; Trask, D. K.; Domann, F. E. Genetically targeted radiotherapy of head and neck squamous cell carcinoma using the sodium-iodide symporter (NIS). Head Neck 2004, 26, 265-271.
    • (2004) Head Neck , vol.26 , pp. 265-271
    • Gaut, A.W.1    Niu, G.2    Krager, K.J.3    Graham, M.M.4    Trask, D.K.5    Domann, F.E.6
  • 145
    • 23844522829 scopus 로고    scopus 로고
    • A novel therapeutic strategy for medullary thyroid cancer based on
    • Cengic, N.; Baker, C. H.; Schütz, M.; Göke, B.; Morris, J. C.; Spitzweg, C. A novel therapeutic strategy for medullary thyroid cancer based on radioiodine therapy following tissue-specific sodium iodide symporter gene expression. J. Clin. Endocrinol. Metab. 2005, 90, 4457-4464.
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 4457-4464
    • Cengic, N.1    Baker, C.H.2    Schütz, M.3    Göke, B.4    Morris, J.C.5    Spitzweg, C.6
  • 147
    • 14644395560 scopus 로고    scopus 로고
    • In vivo radioiodide imaging and treatment of breast cancer xenografts after MUC1-driven expression of the sodium iodide symporter
    • Dwyer, R. M.; Bergert, E. R.; O'Connor, M. K.; Gendler, S. J.; Morris, J. C. In vivo radioiodide imaging and treatment of breast cancer xenografts after MUC1-driven expression of the sodium iodide symporter. Clin. Cancer Res. 2005, 11, 1483-1489.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 1483-1489
    • Dwyer, R.M.1    Bergert, E.R.2    O'Connor, M.K.3    Gendler, S.J.4    Morris, J.C.5
  • 148
    • 33745643772 scopus 로고    scopus 로고
    • Adenovirus-mediated and targeted expression of the sodium-iodide symporter permits in vivo radioiodide imaging and therapy of pancreatic tumors
    • Dwyer, R. M.; Bergert, E. R.; O'Connor, M. K.; Gendler, S. J.; Morris, J. C. Adenovirus-mediated and targeted expression of the sodium-iodide symporter permits in vivo radioiodide imaging and therapy of pancreatic tumors. Hum. Gene Ther. 2006, 17, 661-668.
    • (2006) Hum. Gene Ther. , vol.17 , pp. 661-668
    • Dwyer, R.M.1    Bergert, E.R.2    O'Connor, M.K.3    Gendler, S.J.4    Morris, J.C.5
  • 149
    • 29244483087 scopus 로고    scopus 로고
    • Sodium iodide symporter-mediated radioiodide imaging and therapy of ovarian tumor xenografts in mice
    • Dwyer, R. M.; Bergert, E. R.; O'Connor, M. K.; Gendler, S. J.; Morris, J. C. Sodium iodide symporter-mediated radioiodide imaging and therapy of ovarian tumor xenografts in mice. Gene Ther. 2006, 13, 60-66.
    • (2006) Gene Ther. , vol.13 , pp. 60-66
    • Dwyer, R.M.1    Bergert, E.R.2    O'Connor, M.K.3    Gendler, S.J.4    Morris, J.C.5
  • 150
    • 35348873214 scopus 로고    scopus 로고
    • In vivo radioiodide imaging and treatment of pancreatic cancer xenografts after MUC1 promoter- Driven expression of the human sodium-iodide symporter
    • Chen, R. F.; Li, Z. H.; Pan, Q. H.; Zhou, J. J.; Tang, Q. B.; Yu, F. Y.; Zhou, Q. B.; Wang, J.; Chen, J. S. In vivo radioiodide imaging and treatment of pancreatic cancer xenografts after MUC1 promoter- driven expression of the human sodium-iodide symporter. Pancreatology 2007, 7, 505-513.
    • (2007) Pancreatology , vol.7 , pp. 505-513
    • Chen, R.F.1    Li, Z.H.2    Pan, Q.H.3    Zhou, J.J.4    Tang, Q.B.5    Yu, F.Y.6    Zhou, Q.B.7    Wang, J.8    Chen, J.S.9
  • 151
    • 35348860352 scopus 로고    scopus 로고
    • Image-guided radioiodide therapy of medullary thyroid cancer after carcinoembryonic antigen promoter-targeted sodium iodide symporter gene expression
    • Spitzweg, C.; Baker, C. H.; Bergert, E. R.; O'Connor, M. K.; Morris, J. C. Image-guided radioiodide therapy of medullary thyroid cancer after carcinoembryonic antigen promoter-targeted sodium iodide symporter gene expression. Hum. Gene Ther. 2007, 18, 916-924.
    • (2007) Hum. Gene Ther. , vol.18 , pp. 916-924
    • Spitzweg, C.1    Baker, C.H.2    Bergert, E.R.3    O'Connor, M.K.4    Morris, J.C.5
  • 156
    • 1442356959 scopus 로고    scopus 로고
    • Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter
    • Dingli, D.; Peng, K. W.; Harvey, M. E.; Greipp, P. R.; O'Connor, M. K.; Cattaneo, R.; Morris, J. C.; Russell, S. J. Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter. Blood 2004, 103, 1641-1646.
    • (2004) Blood , vol.103 , pp. 1641-1646
    • Dingli, D.1    Peng, K.W.2    Harvey, M.E.3    Greipp, P.R.4    O'Connor, M.K.5    Cattaneo, R.6    Morris, J.C.7    Russell, S.J.8
  • 157
    • 33645663329 scopus 로고    scopus 로고
    • Dual therapy of ovarian cancer using measles viruses expressing carcinoembryonic antigen and sodium iodide symporter
    • Hasegawa, K.; Pham, L.; O'Connor, M. K.; Federspiel, M. J.; Russell, S. J.; Peng, K. W. Dual therapy of ovarian cancer using measles viruses expressing carcinoembryonic antigen and sodium iodide symporter. Clin. Cancer Res. 2006, 12, 1868-1875.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 1868-1875
    • Hasegawa, K.1    Pham, L.2    O'Connor, M.K.3    Federspiel, M.J.4    Russell, S.J.5    Peng, K.W.6
  • 158
    • 33750991046 scopus 로고    scopus 로고
    • In vivo quantitation of intratumoral radioisotope uptake using micro-single photon emission computed tomography/computed tomography
    • Carlson, S. K.; Classic, K. L.; Hadac, E. M.; Bender, C. E.; Kemp, B. J.; Lowe, V. J.; Hoskin, T. L.; Russell, S. J. In vivo quantitation of intratumoral radioisotope uptake using micro-single photon emission computed tomography/computed tomography. Mol. Imaging Biol. 2006, 8, 324-332.
    • (2006) Mol. Imaging Biol. , vol.8 , pp. 324-332
    • Carlson, S.K.1    Classic, K.L.2    Hadac, E.M.3    Bender, C.E.4    Kemp, B.J.5    Lowe, V.J.6    Hoskin, T.L.7    Russell, S.J.8
  • 159
    • 58149269201 scopus 로고    scopus 로고
    • Quantitative molecular imaging of viral therapy for pancreatic cancer using an engineered measles virus expressing the sodium-iodide symporter reporter gene
    • Carlson, S. K.; Classic, K. L.; Hadac, E. M.; Dingli, D.; Bender, C. E.; Kemp, B. J.; Russell, S. J. Quantitative molecular imaging of viral therapy for pancreatic cancer using an engineered measles virus expressing the sodium-iodide symporter reporter gene. AJR Am. J. Roentgenol. 2009, 192, 279-287.
    • (2009) AJR Am. J. Roentgenol. , vol.192 , pp. 279-287
    • Carlson, S.K.1    Classic, K.L.2    Hadac, E.M.3    Dingli, D.4    Bender, C.E.5    Kemp, B.J.6    Russell, S.J.7
  • 162
    • 0031798905 scopus 로고    scopus 로고
    • Thyroid dosimetry of adult European populations
    • O'Hare, N. J.; Murphy, D.; Malone, J. F. Thyroid dosimetry of adult European populations. Br. J. Radiol. 1998, 71, 535-543.
    • (1998) Br. J. Radiol. , vol.71 , pp. 535-543
    • O'Hare, N.J.1    Murphy, D.2    Malone, J.F.3
  • 163
    • 85047681191 scopus 로고    scopus 로고
    • Clinical review 128: Current approaches to primary therapy for papillary and follicular thyroid cancer
    • Mazzaferri, E. L.; Kloos, R. T. Clinical review 128: Current approaches to primary therapy for papillary and follicular thyroid cancer. J. Clin. Endocrinol. Metab. 2001, 86, 1447-1463.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 1447-1463
    • Mazzaferri, E.L.1    Kloos, R.T.2
  • 164
    • 0034518745 scopus 로고    scopus 로고
    • Radioiodine treatment for differentiated thyroid cancer
    • Vini, L.; Harmer, C. Radioiodine treatment for differentiated thyroid cancer. Clin. Oncol. (R Coll. Radiol. ) 2000, 12, 365-372.
    • (2000) Clin. Oncol. (R Coll. Radiol. ) , vol.12 , pp. 365-372
    • Vini, L.1    Harmer, C.2
  • 165
    • 0031702668 scopus 로고    scopus 로고
    • Intermediate and long-term side effects of high-dose radioiodine therapy for thyroid carcinoma
    • Alexander, C.; Bader, J. B.; Schaefer, A.; Finke, C.; Kirsch, C. M. Intermediate and long-term side effects of high-dose radioiodine therapy for thyroid carcinoma. J. Nucl. Med. 1998, 39, 1551-1554.
    • (1998) J. Nucl. Med. , vol.39 , pp. 1551-1554
    • Alexander, C.1    Bader, J.B.2    Schaefer, A.3    Finke, C.4    Kirsch, C.M.5
  • 166
    • 84961056233 scopus 로고
    • The relation of radioiodine dosimetry to results and complications in the treatment of metastatic thyroid cancer
    • Benua, R.; Cicale, N. R.; Sonenberg, M.; Rawson, R. W. The relation of radioiodine dosimetry to results and complications in the treatment of metastatic thyroid cancer. Am. J. Roentgenol. Radium Ther. Nucl. Med. 1962, 87, 171-182.
    • (1962) Am. J. Roentgenol. Radium Ther. Nucl. Med. , vol.87 , pp. 171-182
    • Benua, R.1    Cicale, N.R.2    Sonenberg, M.3    Rawson, R.W.4
  • 167
    • 0026769603 scopus 로고
    • Radioiodine-131 therapy for well differentiated thyroid cancer - A quantitative radiation dosimetric approach: Outcome and validation in 85 patients
    • Maxon, H. R. III.; Englaro, E. E.; Thomas, S. R.; Hertzberg, V. S.; Hinnefeld, J. D.; Chen, L. S.; Smith, H.; Cummings, D.; Aden, M. D. Radioiodine-131 therapy for well differentiated thyroid cancer - a quantitative radiation dosimetric approach: outcome and validation in 85 patients. J. Nucl. Med. 1992, 33, 1132-1136.
    • (1992) J. Nucl. Med. , vol.33 , pp. 1132-1136
    • Iii, M.H.R.1    Englaro, E.E.2    Thomas, S.R.3    Hertzberg, V.S.4    Hinnefeld, J.D.5    Chen, L.S.6    Smith, H.7    Cummings, D.8    Aden, M.D.9
  • 168
    • 0017239620 scopus 로고
    • Use of lithium as an adjunct to radioiodine therapy of thyroid carcinoma
    • Gershengorn, M. C.; Izumi, M.; Robbins, J. Use of lithium as an adjunct to radioiodine therapy of thyroid carcinoma. J. Clin. Endocrinol. Metab. 1976, 42, 105-111.
    • (1976) J. Clin. Endocrinol. Metab. , vol.42 , pp. 105-111
    • Gershengorn, M.C.1    Izumi, M.2    Robbins, J.3
  • 169
    • 0013575994 scopus 로고    scopus 로고
    • The value of lithium in radioiodine therapy of thyroid carcinoma
    • Medeiros-Neto, G.; Gaitan, E., Eds. Plenum Press: New York
    • Movius, E. G.; Robbins, J.; Pierce, L. R.; Reynolds, J. C.; Keenan, A. M.; Phyillaier, M. A. The value of lithium in radioiodine therapy of thyroid carcinoma. In: Medeiros-Neto, G.; Gaitan, E., Eds. Frontiers in Thyroidology. Plenum Press: New York, 1996, Vol.2, pp. 1269-1272.
    • (1996) Frontiers in Thyroidology , vol.2 , pp. 1269-1272
    • Movius, E.G.1    Robbins, J.2    Pierce, L.R.3    Reynolds, J.C.4    Keenan, A.M.5    Phyillaier, M.A.6
  • 172
    • 33744954241 scopus 로고    scopus 로고
    • Treatment with drugs able to reduce iodine efflux significantly increases the intracellular retention time in thyroid cancer cells stably transfected with sodium iodide symporter complementary deoxyribonucleic acid
    • Elisei, R.; Vivaldi, A.; Ciampi, R.; Faviana, P.; Basolo, F.; Santini, F.; Traino, C.; Pacini, F.; Pinchera, A. Treatment with drugs able to reduce iodine efflux significantly increases the intracellular retention time in thyroid cancer cells stably transfected with sodium iodide symporter complementary deoxyribonucleic acid. J. Clin. Endocrinol. Metab. 2006, 91, 2389-2395.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 2389-2395
    • Elisei, R.1    Vivaldi, A.2    Ciampi, R.3    Faviana, P.4    Basolo, F.5    Santini, F.6    Traino, C.7    Pacini, F.8    Pinchera, A.9
  • 173
    • 17944375922 scopus 로고    scopus 로고
    • Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer
    • Huang, M.; Batra, R. K.; Kogai, T.; Lin, Y. Q.; Hershman, J. M.; Lichtenstein, A.; Sharma, S.; Zhu, L. X.; Brent, G. A.; Dubinett, S. M. Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer. Cancer Gene Ther. 2001, 8, 612-618.
    • (2001) Cancer Gene Ther. , vol.8 , pp. 612-618
    • Huang, M.1    Batra, R.K.2    Kogai, T.3    Lin, Y.Q.4    Hershman, J.M.5    Lichtenstein, A.6    Sharma, S.7    Zhu, L.X.8    Brent, G.A.9    Dubinett, S.M.10
  • 174
    • 0036148836 scopus 로고    scopus 로고
    • Transposition of the thyroid iodide uptake and organification system in nonthyroid tumor cells by adenoviral vector-mediated gene transfers
    • Boland, A.; Magnon, C.; Filetti, S.; Bidart, J. M.; Schlumberger, M.; Yeh, P.; Perricaudet, M. Transposition of the thyroid iodide uptake and organification system in nonthyroid tumor cells by adenoviral vector-mediated gene transfers. Thyroid 2002, 12, 19-26.
    • (2002) Thyroid , vol.12 , pp. 19-26
    • Boland, A.1    Magnon, C.2    Filetti, S.3    Bidart, J.M.4    Schlumberger, M.5    Yeh, P.6    Perricaudet, M.7
  • 175
    • 0036963506 scopus 로고    scopus 로고
    • Iodide kinetics and experimental 131I therapy in a xenotransplanted human sodium- Iodide symporter-transfected human follicular thyroid carcinoma cell line
    • Smit, J. W.; Schroder-van der Elst, J. P.; Karperien, M.; Que, I.; Stokkel, M.; van der Heide, D.; Romijn, J. A. Iodide kinetics and experimental 131I therapy in a xenotransplanted human sodium- iodide symporter-transfected human follicular thyroid carcinoma cell line. J. Clin. Endocrinol. Metab. 2002, 87, 1247-1253.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 1247-1253
    • Smit, J.W.1    Schroder-Van Der Elst, J.P.2    Karperien, M.3    Que, I.4    Stokkel, M.5    Van Der Heide, D.6    Romijn, J.A.7
  • 176
    • 0036153579 scopus 로고    scopus 로고
    • Rhenium-188 as an alternative to Iodine-131 for treatment of breast tumors expressing the sodium/iodide symporter (NIS)
    • Dadachova, E.; Bouzahzah, B.; Zuckier, L. S.; Pestell, R. G. Rhenium-188 as an alternative to Iodine-131 for treatment of breast tumors expressing the sodium/iodide symporter (NIS). Nucl. Med. Biol. 2002, 29, 13-18.
    • (2002) Nucl. Med. Biol. , vol.29 , pp. 13-18
    • Dadachova, E.1    Bouzahzah, B.2    Zuckier, L.S.3    Pestell, R.G.4
  • 178
    • 2342583415 scopus 로고    scopus 로고
    • Kinetics of perrhenate uptake and comparative biodistribution of perrhenate, pertechnetate, and iodide by NaI symporter-expressing tissues in vivo
    • Zuckier, L. S.; Dohan, O.; Li, Y.; Chang, C. J.; Carrasco, N.; Dadachova, E. Kinetics of perrhenate uptake and comparative biodistribution of perrhenate, pertechnetate, and iodide by NaI symporter-expressing tissues in vivo. J. Nucl. Med. 2004, 45, 500-507.
    • (2004) J. Nucl. Med. , vol.45 , pp. 500-507
    • Zuckier, L.S.1    Dohan, O.2    Li, Y.3    Chang, C.J.4    Carrasco, N.5    Dadachova, E.6
  • 179
    • 27144519982 scopus 로고    scopus 로고
    • Treatment with rhenium-188-perrhenate and iodine- 131 of NIS-expressing mammary cancer in a mouse model remarkably inhibited tumor growth
    • Dadachova, E.; Nguyen, A.; Lin, E. Y.; Gnatovskiy, L.; Lu, P.; Pollard, J. W. Treatment with rhenium-188-perrhenate and iodine- 131 of NIS-expressing mammary cancer in a mouse model remarkably inhibited tumor growth. Nucl. Med. Biol. 2005, 32, 695-700.
    • (2005) Nucl. Med. Biol. , vol.32 , pp. 695-700
    • Dadachova, E.1    Nguyen, A.2    Lin, E.Y.3    Gnatovskiy, L.4    Lu, P.5    Pollard, J.W.6
  • 181
    • 0642376392 scopus 로고    scopus 로고
    • In vitro cytotoxicity of (211)At-astatide and (131)I-iodide to glioma tumor cells expressing the sodium/iodide symporter
    • Carlin, S.; Akabani, G.; Zalutsky, M. R. In vitro cytotoxicity of (211)At-astatide and (131)I-iodide to glioma tumor cells expressing the sodium/iodide symporter. J. Nucl. Med. 2003, 44, 1827-1838.
    • (2003) J. Nucl. Med. , vol.44 , pp. 1827-1838
    • Carlin, S.1    Akabani, G.2    Zalutsky, M.R.3
  • 182
    • 33644760432 scopus 로고    scopus 로고
    • Effective cancer therapy with the alpha-particle emitter [211At]astatine in a mouse model of genetically modified sodium/iodide symporter-expressing tumors
    • Petrich, T.; Quintanilla-Martinez, L.; Korkmaz, Z.; Samson, E.; Helmeke, H. J.; Meyer, G. J.; Knapp, W. H.; Pötter, E. Effective cancer therapy with the alpha-particle emitter [211At]astatine in a mouse model of genetically modified sodium/iodide symporter-expressing tumors. Clin. Cancer Res. 2006, 12, 1342-1348.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 1342-1348
    • Petrich, T.1    Quintanilla-Martinez, L.2    Korkmaz, Z.3    Samson, E.4    Helmeke, H.J.5    Meyer, G.J.6    Knapp, W.H.7    Pötter, E.8
  • 183
    • 0041814617 scopus 로고    scopus 로고
    • Retinoic acid-induced stimulation of sodium iodide symporter expression and cytotoxicity of radioiodine in prostate cancer cells
    • Spitzweg, C.; Scholz, I. V.; Bergert, E. R.; Tindall, D. J.; Young, C. Y.; Göke, B.; Morris, J. C. Retinoic acid-induced stimulation of sodium iodide symporter expression and cytotoxicity of radioiodine in prostate cancer cells. Endocrinology 2003, 144, 3423-3432.
    • (2003) Endocrinology , vol.144 , pp. 3423-3432
    • Spitzweg, C.1    Scholz, I.V.2    Bergert, E.R.3    Tindall, D.J.4    Young, C.Y.5    Göke, B.6    Morris, J.C.7
  • 184
    • 34247240603 scopus 로고    scopus 로고
    • Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment
    • Lim, S. J.; Paeng, J. C.; Kim, S. J.; Kim, S. Y.; Lee, H.; Moon, D. H. Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment. J. Nucl. Med. 2007, 48, 398-404.
    • (2007) J. Nucl. Med. , vol.48 , pp. 398-404
    • Lim, S.J.1    Paeng, J.C.2    Kim, S.J.3    Kim, S.Y.4    Lee, H.5    Moon, D.H.6
  • 188
    • 14844359242 scopus 로고    scopus 로고
    • Radiobiologic principles in radionuclide therapy
    • Kassis, A. I.; Adelstein, S. J. Radiobiologic principles in radionuclide therapy. J. Nucl. Med. 2005, 46(Suppl 1), 4S-12S.
    • (2005) J. Nucl. Med. , vol.46 , Issue.SUPPL. 1
    • Kassis, A.I.1    Adelstein, S.J.2
  • 189
    • 0031658476 scopus 로고    scopus 로고
    • Survival and DNA damage in Chinese hamster V79 cells exposed to alpha particles emitted by DNA-incorporated astatine-211
    • Walicka, M. A.; Vaidyanathan, G.; Zalutsky, M. R.; Adelstein, S. J.; Kassis, A. I. Survival and DNA damage in Chinese hamster V79 cells exposed to alpha particles emitted by DNA-incorporated astatine-211. Radiat. Res. 1998, 150, 263-268.
    • (1998) Radiat. Res. , vol.150 , pp. 263-268
    • Walicka, M.A.1    Vaidyanathan, G.2    Zalutsky, M.R.3    Adelstein, S.J.4    Kassis, A.I.5
  • 191
    • 0028204813 scopus 로고
    • A comparison of experimental and calculated survival curves for V79 cells grown as monolayers or in suspension exposed to alpha irradiation from 212Bi distributed in the growth medium
    • Charlton, D. E.; Kassis, A. I.; Adelstein, S. J. A comparison of experimental and calculated survival curves for V79 cells grown as monolayers or in suspension exposed to alpha irradiation from 212Bi distributed in the growth medium. Radiat. Prot. Dosim. 1994, 52, 311-315.
    • (1994) Radiat. Prot. Dosim. , vol.52 , pp. 311-315
    • Charlton, D.E.1    Kassis, A.I.2    Adelstein, S.J.3
  • 192
    • 0344442900 scopus 로고    scopus 로고
    • In vivo imaging and tumor therapy with the sodium iodide symporter
    • Dingli, D.; Russell, S. J.; Morris, J. C. 3rd. In vivo imaging and tumor therapy with the sodium iodide symporter. J. Cell Biochem. 2003, 90, 1079-1086.
    • (2003) J. Cell Biochem. , vol.90 , pp. 1079-1086
    • Dingli, D.1    Russell, S.J.2    Morris III, J.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.