Expression of the Na+/I- symporter gene in human thyroid tumors: A comparison study with other thyroid-specific genes

Journal of Clinical Endocrinology and Metabolism

Volumn 84, Issue 9, 1999, Pages 3228-3234

  Lazar, Vladimir ^a   Bidart, Jean Michel ^a   Caillou, Bernard ^a   Mahé, Cedric ^a   Lacroix, Ludovic ^a   Filetti, Sebastiano ^b   Schlumberger, Martin ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b Policlinico Mater Domini   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE DERIVATIVE; GLUCOSE TRANSPORTER; IODIDE ION; IODINE 131; MESSENGER RNA; SODIUM ION; TAQ POLYMERASE; THYROGLOBULIN; THYROTROPIN RECEPTOR; TRACER;

ADULT; ARTICLE; CANCER STAGING; CONTROLLED STUDY; FEMALE; FLUORESCENCE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GRAVES DISEASE; HUMAN; HUMAN TISSUE; IODINE 131 UPTAKE TEST; MAJOR CLINICAL STUDY; MALE; METASTASIS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RNA ANALYSIS; THYROID ADENOMA; THYROID CARCINOMA; THYROID FUNCTION; THYROID TUMOR; TISSUE SPECIFICITY;

EID: 0033305355     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.84.9.3228     Document Type: Article

References (38)

1. Iodide transport in the thyroid gland
2. Iodine metabolism and thyroid physiology: Current concepts
3. Cloning and characterization of the thyroid iodide transporter
4. Cloning of the human sodium iodide symporter
5. Expression, exon-intron organization, and chromosome mapping of the human sodium iodide symporter
6. Isolation of a complementary DNA clone for thyroid microsomal antigen. Homology with the gene for thyroid peroxidase
7. Primary structure of human thyroglobulin deduced from the sequence of its 8448-base complementary DNA
8. Human thyrotropin receptor gene: Expression in thyroid tumors and correlation to markers of thyroid differentiation and dedifferentiation
9. Isolation of TSH and LH/CG receptor cDNAs from human thyroid: Regulation by tissue specific splicing
10. Human thyroid peroxidase activity in benign and malignant thyroid disorders
11. Thyroid proteins and hormone synthesis in human thyroid cancer
12. Thyroid peroxidase, thyroglobulin, cAMP and DNA in human thyroid
13. Gene expression of differentiation- and dedifferentiation markers in normal and malignant human thyroid tissues
14. Expression of thyrotropin receptor (TSH-R), thyroglobulin, thyroperoxidase, and calcitonin messenger ribonucleic acids in thyroid carcinomas: Evidence of TSH-R gene transcript in medullary histotype
15. Immunohistochemical loss of thyroid peroxidase in papillary thyroid carcinoma: Strong suppression of peroxidase gene expression
16. Mechanisms of nonneoplastic endocrine hyperplasia- a changing concept: A review focused on the thyroid gland
17. Increased expression of the sodium/iodide symporter in papillary thyroid carcinomas
18. Iodide symporter gene expression in human thyroid tumors
19. - symporter in human thyroid tissues: An immunohistochemical study
20. - symporter in human thyroid tissues and salivary gland tissues
21. Circulating thyroglobulin and thyroid hormones in patients with metastases of differentiated thyroid carcinoma: Relationship to serum thyrotropin levels
22. Radioactive iodine treatment and external radiotherapy for lung and bone metastases from thyroid carcinoma
23. Relationship between thyrotropin stimulation and radioiodine uptake in lung metastases of differentiated thyroid carcinoma
24. Fluorine-18-FDG and iodine-131-iodide uptake in thyroid cancer
25. Molecular mechanisms of the increased glucose transport in transformed FRTL-5 rat thyroid cells
26. Structure of the human Na+/glucose cotransporter gene SGTL1
27. GLUT1 glucose transporter expression in benign and malignant thyroid nodules
28. A novel method for real time quantitative RT-PCR
29. Histological typing of thyroid tumours
30. Transcriptional regulation of muscle-specific genes during myoblast differentiation
31. Distinct molecular phenotypes in murine cardiac muscle development, growth, and hypertrophy
32. - symporter in cultured human thyroid cells exposed to thyrotropin and in Graves' thyroid tissue
33. Development of reverse transcription-competitive polymerase chain reaction method to quantitate the expression levels of human sodium iodide symporter
34. Expression of thyroid-specific transcription factors TTF-I and PAX-8 in human thyroid neoplasms
35. - symporter gene expression
36. - symporter
37. The paired-domain transcription factor Pax-8 binds to the upstream enhancer of the rat sodium/Iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription