Mechanistic investigations of the dehydration reaction of lacticin 481 synthetase using site-directed mutagenesis

Biochemistry

Volumn 46, Issue 20, 2007, Pages 5991-6000

  Young, Ok You ^a   Van Der Donk, Wilfred A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEHYDRATASE; ELIMINATION ACTIVITY; MUTANTS; MUTATION;

AMINO ACIDS; CROSSLINKING; DEHYDRATION; MUTAGENESIS; PEPTIDES; PHOSPHORYLATION;

ENZYMES;

ALANINE; ARGININE; ASPARAGINE; ASPARTIC ACID; BUTYRIC ACID DERIVATIVE; DEHYDROALANINE; DEHYDROBUTYRINE; GLUTAMIC ACID; HISTIDINE; LACTICIN 481 SYNTHETASE; LANTIBIOTIC; LEUCINE; LYSINE; METHIONINE; MUTANT PROTEIN; PHOSPHATE; SERINE; SYNTHETASE; THREONINE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CROSS LINKING; DEHYDRATION; ELIMINATION REACTION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REACTION ANALYSIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ARGININE; ASPARTIC ACID; BACTERIOCINS; DESICCATION; ENZYMES; HISTIDINE; LYSINE; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; SUBSTRATE SPECIFICITY; TYROSINE;

EID: 34249111878     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi602663x     Document Type: Article

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