The phosphothreonine lyase activity of a bacterial type III effector family

Science

Volumn 315, Issue 5814, 2007, Pages 1000-1003

  Li, Hongtao ^a   Xu, Hao ^a   Zhou, Yan ^a   Zhang, Jie ^a   Long, Chengzu ^a   Li, Shuqin ^a   Chen, She ^a   Zhou, Jian Min ^a   Shao, Feng ^a  

^a NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; LYASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATE; PHOSPHOTHREONINE; PHOSPHOTHREONINE LYASE; PHOSPHOTYROSINE; PROTEIN OSPF; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

BACTERIUM; ENZYME ACTIVITY; PATHOGEN; PROTEIN; SIGNAL;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; SHIGELLA; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; CELL LINE; HELA CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; SALMONELLA TYPHIMURIUM; SHIGELLA FLEXNERI; TYROSINE;

BACTERIA (MICROORGANISMS); SHIGELLA;

EID: 33847154642     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1138960     Document Type: Article

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20. We thank J. Dixon for critical reading of this manuscript; K. Guan, J. Dixon, M. Cobb, M. Solomon, A. Lin, T. Mustelin, M. Donnenberg, and N. Ahn for providing reagents; W. Luo for providing technical suggestions about bacteria recombination; and members of the Shao lab for helpful discussions and technical assistance. This work was supported by Chinese Ministry of Science and Technology "863" grants 2005AA210950 (F.S.) and 2003AA210080 (J.-M.Z.).