HSP72 depletion suppresses γh2AX activation by genotoxic stresses via p53/p21 signaling

Oncogene

Volumn 29, Issue 13, 2010, Pages 1952-1962

  Gabai, V L ^a   Sherman, M Y ^a   Yaglom, J A ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Doxorubicine; Hsp72; Nutlin 3; Radiation; Senescence

Indexed keywords

CLENBUTEROL; DOXORUBICIN; GAMMA HISTONE H2AX; HEAT SHOCK PROTEIN 72; HISTONE H2AX; P21 ACTIVATED KINASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOWN REGULATION; ENZYME ACTIVATION; GAMMA IRRADIATION; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIOSENSITIZATION; TUMOR CELL;

ANIMALS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DNA REPAIR; DOWN-REGULATION; GENE KNOCKOUT TECHNIQUES; HISTONES; HSP72 HEAT-SHOCK PROTEINS; HUMANS; MICE; PROTEIN KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 77950520346     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2009.480     Document Type: Article

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