Triggering senescence programs suppresses Chk1 kinase and sensitizes cells to genotoxic stresses

Cancer Research

Volumn 68, Issue 6, 2008, Pages 1834-1842

  Gabai, Vladimir L ^a   O'Callaghan Sunol, Cornelia ^a   Meng, Le ^a   Sherman, Michael Y ^a   Yaglom, Julia ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CAMPTOTHECIN; CHAPERONE; CHECKPOINT KINASE 1; CYCLIN DEPENDENT KINASE 1; HEAT SHOCK PROTEIN 72; PROTEIN P16; PROTEIN P21; PROTEIN P53; RAD17 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL STRESS; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENESCENCE; ULTRAVIOLET C RADIATION;

ANEUPLOIDY; CAMPTOTHECIN; CELL AGING; CELL CYCLE; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DNA REPAIR; DOWN-REGULATION; ENZYME ACTIVATION; HCT116 CELLS; HELA CELLS; HSP72 HEAT-SHOCK PROTEINS; HUMANS; NEOPLASMS; PROTEIN KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 40949092071     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-5656     Document Type: Article

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