Intra-accumbens amphetamine increases the conditioned incentive salience of sucrose reward: Enhancement of reward 'wanting' without enhanced 'liking' or response reinforcement

Journal of Neuroscience

Volumn 20, Issue 21, 2000, Pages 8122-8130

  Wyvell, C L ^a   Berridge, K C ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Addiction; Conditioned stimulus; Dopamine; Hedonia; Incentive; Incentive salience; Instrumental; Learning; Limbic; Mesolimbic; Motivation; Palatability; Pavlovian; Reinforcement; Reward; Shell; Taste reactivity; Ventral striatum

Indexed keywords

AMPHETAMINE; DOPAMINE; SUCROSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONDITIONED REFLEX; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC TRANSMISSION; FEMALE; LEARNING; LIMBIC CORTEX; MOTIVATION; NEUROTRANSMISSION; NONHUMAN; NUCLEUS ACCUMBENS; PALATABILITY; PERFORMANCE; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD;

EID: 0034331220     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-21-08122.2000     Document Type: Article

References (78)

1. Dopaminergic correlates of sensory-specific satiety in the medial prefrontal cortex and nucleus accumbens of the rat
2. Asymmetrical interactions between thirst and hunger in Pavlovian-instrumental transfer
3. Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments
4. Feeding induced by GABA(A) receptor stimulation within the nucleus accumbens shell: Regional mapping and characterization of macronutrient and taste preference
5. Hypothalamic stimulation facilitates contralateral visual control of a learned response
6. Experimental sodium depletion and salt taste in normal human volunteers
7. Modulation of taste affect by hunger, caloric satiety, and sensory-specific satiety in the rat
8. Food reward: Brain substrates of 'wanting' and 'liking.'
9. Taste reactivity: Measuring hedonic impact in human infants and animals
10. Reward learning: Reinforcement, incentives, and expectations
11. Benzodiazepines, appetite, and taste palatability
12. What is the role of dopamine in reward: Hedonic impact, reward learning, or incentive salience?
13. Palatability shift of a salt-associated incentive during sodium depletion
14. What psychological process mediates feeding evoked by electrical stimulation of the lateral hypothalamus?
15. Sodium depletion enhances salt palatability in rats
16. Taste-reactivity analysis of 6-hydroxydopamine-induced aphagia: Implications for arousal and anhedonia hypotheses of dopamine function
17. Dopamine and preparatory behavior. II. A neurochemical analysis
18. Conditioned reversal of reactions to normally avoided tastes
19. Auto-shaping of the pigeon's key-peck
20. Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and medial prefrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions of D-amphetamine
21. Sensory pleasure
22. Limbic-striatal interactions in reward-related processes: Modulation by the dopaminergic system
23. Anatomical dissociation of amphetamine's rewarding and aversive effects: An intracranial microinjection study
24. The effect of early feeding experience on signal-directed response topography in the rat
25. Control of fluid palatability by exteroceptive Pavlovian signals
26. Dopaminergic mechanisms mediating the incentive to seek cocaine and heroin following long-term withdrawal of IV drug self-administration
27. A motivational learning hypothesis of the role of mesolimbic dopamine in compulsive drug use
28. The relation between oxidation currents in the nucleus accumbens and conditioned increases in motor activity in rats following repeated administration of D-amphetamine or cocaine
29. Conditioned changes in oxidation currents in the nucleus accumbens of rats by stimuli paired with self-administration or yoked administration of D-amphetamine
30. Motivational control of goal-directed action
31. Pavlovian processes in the motivational control of instrumental performance
32. Dissociation of Pavlovian and instrumental incentive learning under dopamine antagonists
33. Morphine enhances hedonic taste palatability in rats
34. Amygdala-ventral striatal interactions and reward-related processes
35. Differential involvement of amygdala subsystems in appetitive conditioning and drug addiction
36. Facilitation of sexual behavior in male rats following D-amphetamine-induced behavioral sensitization
37. Drug craving and positive-negative hedonic brain substrates activated by addicting drugs
38. Taste reactivity as a measure of the neural control of palatability
39. The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats
40. Enhanced appetitive conditioning following repeated pretreatment with D-amphetamine
41. Food reward and cocaine increase extracellular dopamine in the nucleus accumbens as measured by dialysis
42. Dopamine and conditioned reinforcement. I. Differential effects of amphetamine microinjections into striatal subregions
43. Pleasantness of a sweet taste during hunger and satiety: Effects of gender and 'sweet tooth.'
44. An appetitively conditioned taste elicits a preferential increase in mesolimbic dopamine release
45. Haloperidol does not affect motivational processes in an operant runway model of food-seeking behavior
46. Effects of post-training D-amphetamine on acquisition of an appetitive autoshaped lever press response in rats
47. Neuroanatomical patterns of fos-like immuno-reactivity induced by a palatable meal and meal-paired environment in saline- and naltrexone-treated rats
48. Dissociation in effects of lesions of the nucleus accumbens core and shell on appetitive Pavlovian approach behavior and the potentiation of conditioned reinforcement and locomotor activity by D-amphetamine
49. Brainstem mediates diazepam enhancement of palatability and feeding: Microinjections into fourth versus lateral ventricle
50. Opioid site in nucleus accumbens shell for food intake and hedonic impact: Mapping by microinjection Fos plumes
51. Pimozide does not shift palatability: Separation of anhedonia from sensorimotor effects
52. Increased extracellular dopamine in the nucleus accumbens of the rat elicited by a conditioned stimulus for food: An electrochemical study
53. Mesoaccumbens dopamine-opiate interactions in the control over behaviour by a conditioned reinforcer
54. Pavlovian conditioning and its proper control procedures
55. Spatial contiguity facilitates Pavlovian second-order conditioning
56. Two-process learning theory: Relationship between Pavlovian and instrumental learning
57. Behavior-relevant changes in nucleus accumbens dopamine transmission elicited by food reinforcement: An electrochemical study in rat
58. The neural basis of drug craving: An incentive-sensitization theory of addiction
59. The psychology and neurobiology of addiction: An incentive sensitization view
60. Limbic-striatal interactions in reward-related processes
61. Different effects of haloperidol and extinction in instrumental behaviours
62. Behavioral functions of nucleus accumbens dopamine: Empirical and conceptual problems with the anhedonia hypothesis
63. Reward prediction in pri-mate basal ganglia and frontal cortex
64. Individual differences in sugar consumption following systemic or intraaccumbens administration of low doses of amphetamine in nondeprived rats
65. The role of accumbens dopamine in lever pressing and response allocation: Effects of 6-OHDA injected into core and dorsomedial shell
66. Differential behavioral responses to dopaminergic stimulation of nucleus accumbens subregions in the rat
67. Enhanced responding for conditioned reward produced by intra-accumbens amphetamine is potentiated after cocaine sensitization
68. Enhanced behavioral control by conditioned reinforcers following microinjections of D-amphetamine into the nucleus accumbens
69. Comparing motivational systems: An incentive motivational perspective
70. Locating reward cue at response manipulandum (CAM) induces symptoms of drug abuse
71. A comparison of benzodiazepine, serotonin, and dopamine agents in the taste-reactivity paradigm
72. Reinforcing effects of psychostimulants in humans are associated with increases in brain dopamine and occupancy of D(2) receptors
73. The anhedonia hypothesis: Mark III
74. Neuroleptic-induced 'anhedonia' in rats: Pimozide blocks reward quality of food
75. Intra-accumbens amphetamine enhances the conditioned incentive salience of sucrose reward