Integrin-linked kinase is involved in cocaine sensitization by regulating psd-95 and synapsin i expression and GluR1 Ser845 phosphorylation

Journal of Molecular Neuroscience

Volumn 40, Issue 3, 2010, Pages 284-294

  Chen, Qiang ^a   Zhu, Xiongzhao ^b   Zhang, Yu ^a   Wetsel, William C ^a   Lee, Tong H ^a   Zhang, Xiuwu ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Behavioral sensitization; Cocaine; GluR1; Integrin linked kinase; PSD 95; SiRNA; Synapsin I; Synaptic plasticity

Indexed keywords

COCAINE; GLUTAMATE RECEPTOR 1; INTEGRIN LINKED KINASE; PARVOVIRUS VECTOR; POSTSYNAPTIC DENSITY PROTEIN 95; SERINE; SMALL INTERFERING RNA; SYNAPSIN I;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMOSENSITIZATION; COCAINE DEPENDENCE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG REEXPOSURE; GENE CASSETTE; GENE SILENCING; GENETIC REGULATION; IMMUNOPRECIPITATION; MALE; NERVE CELL PLASTICITY; NONHUMAN; NUCLEUS ACCUMBENS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RAT; REPEAT PROCEDURE; SPRAGUE DAWLEY RAT;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE; COCAINE-RELATED DISORDERS; GENE SILENCING; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; NEURONAL PLASTICITY; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECOMBINANT FUSION PROTEINS; SERINE; SUBSTANCE WITHDRAWAL SYNDROME; SYNAPSINS;

ADENO-ASSOCIATED VIRUS; RATTUS;

EID: 77950187964     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-009-9218-3     Document Type: Article

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