Probing the Pore Drug Binding Site of Microtubules with Fluorescent Taxanes: Evidence of Two Binding Poses

Chemistry and Biology

Volumn 17, Issue 3, 2010, Pages 243-253

  Barasoain, Isabel ^a   García Carril, Ana M ^a   Matesanz, Ruth ^a   Maccari, Giorgio ^b   Trigili, Chiara ^a   Mori, Mattia ^b   Shi, Jing Zhe ^c   Fang, Wei Shuo ^c   Andreu, José M ^a   Botta, Maurizio ^b   Díaz, J Fernando ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b UNIVERSITY OF SIENA   (Italy)

^c INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; TAXOID; TUBULIN MODULATOR;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFOCAL MICROSCOPY; HUMAN; KINETICS; METABOLISM; MICROTUBULE; THERMODYNAMICS; TUMOR CELL CULTURE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BINDING SITES; HUMANS; KINETICS; MICROSCOPY, CONFOCAL; MICROTUBULES; MODELS, MOLECULAR; TAXOIDS; THERMODYNAMICS; TUBULIN MODULATORS; TUMOR CELLS, CULTURED;

EID: 77949549397     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2010.02.006     Document Type: Article

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