Cholesterol trafficking is required for mTOR activation in endothelial cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 10, 2010, Pages 4764-4769

  Xu, Jing ^a   Dang, Yongjun ^a   Ren, Yunzhao R ^a   Liu, Jun O ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; Cholesterol homeostasis; Itraconazole

Indexed keywords

CHOLESTEROL; CYCLIN A; CYCLIN E; CYCLODEXTRIN; FILIPIN; ITRACONAZOLE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN P21; PROTEIN P27; SMALL INTERFERING RNA;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG TARGETING; ENDOSOME; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LYSOSOME; NIEMANN PICK DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANDROSTENES; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CARRIER PROTEINS; CELL CYCLE; CELL LINE; CELL PROLIFERATION; CHOLESTEROL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLODEXTRINS; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HUMANS; IMIPRAMINE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ITRACONAZOLE; MEMBRANE GLYCOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; THAPSIGARGIN; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 77949539205     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0910872107     Document Type: Article

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