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Volumn 62, Issue 1, 2010, Pages 107-113

Anti-ischaemic activity of an antioxidant aldose reductase inhibitor on diabetic and non-diabetic rat hearts

Author keywords

Aldose reductase; Antioxidant effect; Cardiovascular complications; Diabetes; Myocardial ischaemia

Indexed keywords

ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; EPALRESTAT; PYRIDOL[1,2-A]PYRIMIDINE 4 ONE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 77949506243     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.62.01.0012     Document Type: Article
Times cited : (6)

References (27)
  • 1
    • 0022619321 scopus 로고
    • Activation of human erythrocyte, brain, aorta, muscle, and ocular tissue aldose reductase
    • Srivastava SK et al. Activation of human erythrocyte, brain, aorta, muscle, and ocular tissue aldose reductase. Metabolism 1986; 35: 114-118.
    • (1986) Metabolism , vol.35 , pp. 114-118
    • Srivastava, S.K.1
  • 2
    • 0027318772 scopus 로고
    • Hyperglycemic pseudohypoxia and diabetic complications
    • Williamson JR et al. Hyperglycemic pseudohypoxia and diabetic complications. Diabetes 1993; 42: 801-813.
    • (1993) Diabetes , vol.42 , pp. 801-813
    • Williamson, J.R.1
  • 3
    • 0030885397 scopus 로고    scopus 로고
    • Glucose-specific regulation of aldose reductase in Capan-1 human pancreatic duct cells in vitro
    • Busik JV et al. Glucose-specific regulation of aldose reductase in Capan-1 human pancreatic duct cells in vitro. J Clin Invest 1997; 100: 1685-1692.
    • (1997) J Clin Invest , vol.100 , pp. 1685-1692
    • Busik, J.V.1
  • 4
    • 34247376024 scopus 로고    scopus 로고
    • The activity of aldose reductase is elevated in diabetic mouse heart
    • Iwata K et al. The activity of aldose reductase is elevated in diabetic mouse heart. J Pharmacol Sci 2007; 103: 408-416.
    • (2007) J Pharmacol Sci , vol.103 , pp. 408-416
    • Iwata, K.1
  • 5
    • 0031920049 scopus 로고    scopus 로고
    • Aldose reductase in glucose toxicity: A potential target for the prevention of diabetic complications
    • Yabe-Nishimura C. Aldose reductase in glucose toxicity: a potential target for the prevention of diabetic complications. Pharmacol Rev 1998; 50: 21-33.
    • (1998) Pharmacol Rev , vol.50 , pp. 21-33
    • Yabe-Nishimura, C.1
  • 6
    • 33750867930 scopus 로고    scopus 로고
    • Metabolic effects of aldose reductase inhibition during low-flow ischemia and reperfusion
    • Ramasamy R et al. Metabolic effects of aldose reductase inhibition during low-flow ischemia and reperfusion. Am J Physiol 1998; 275: H195-H203.
    • (1998) Am J Physiol , vol.275
    • Ramasamy, R.1
  • 7
    • 33748954996 scopus 로고    scopus 로고
    • Aldose reductase inhibitors improve myocardial reperfusion injury in mice by a dual mechanism
    • Iwata K et al. Aldose reductase inhibitors improve myocardial reperfusion injury in mice by a dual mechanism. J Pharmacol Sci 2006; 102: 37-46.
    • (2006) J Pharmacol Sci , vol.102 , pp. 37-46
    • Iwata, K.1
  • 8
    • 34547483879 scopus 로고    scopus 로고
    • Therapeutic regulation of endothelial dysfunction in type 2 diabetes mellitus
    • Hamilton SJ et al. Therapeutic regulation of endothelial dysfunction in type 2 diabetes mellitus. Diab Vasc Dis Res 2007; 4: 89-102.
    • (2007) Diab Vasc Dis Res , vol.4 , pp. 89-102
    • Hamilton, S.J.1
  • 9
    • 34547485312 scopus 로고    scopus 로고
    • The endothelium and vascular inflammation in diabetes
    • Hartge MM et al. The endothelium and vascular inflammation in diabetes. Diab Vasc Dis Res 2007; 4: 84-88.
    • (2007) Diab Vasc Dis Res , vol.4 , pp. 84-88
    • Hartge, M.M.1
  • 10
    • 0029063110 scopus 로고
    • Substrate specificity of human aldose reductase: Identification of 4-hydroxynonenal as an endogenous substrate
    • Vander Jagt DL et al. Substrate specificity of human aldose reductase: identification of 4-hydroxynonenal as an endogenous substrate. Biochim Biophys Acta 1995; 1249: 117-126.
    • (1995) Biochim Biophys Acta , vol.1249 , pp. 117-126
    • Vander Jagt, D.L.1
  • 11
    • 0031930041 scopus 로고    scopus 로고
    • Cardiac reperfusion injury: Aging, lipid peroxidation, and mitochondrial dysfunction
    • Lucas DT, Szweda LI. Cardiac reperfusion injury: aging, lipid peroxidation, and mitochondrial dysfunction. Proc Natl Acad Sci USA 1998; 95: 510-514.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 510-514
    • Lucas, D.T.1    Szweda, L.I.2
  • 12
    • 0032921371 scopus 로고    scopus 로고
    • Formation of 4-hydroxy-2-nonenal-modified proteins in ischemic rat heart
    • Eaton P et al. Formation of 4-hydroxy-2-nonenal-modified proteins in ischemic rat heart. Am J Physiol 1999; 276: H935-H943.
    • (1999) Am J Physiol , vol.276
    • Eaton, P.1
  • 13
    • 0037047696 scopus 로고    scopus 로고
    • Aldose reductase is an obligatory mediator of the late phase of ischemic preconditioning
    • Shinmura K et al. Aldose reductase is an obligatory mediator of the late phase of ischemic preconditioning. Circ Res 2002; 91: 240-246.
    • (2002) Circ Res , vol.91 , pp. 240-246
    • Shinmura, K.1
  • 14
    • 0022374267 scopus 로고
    • Role of aldose reductase in the development of diabetes associated complications
    • Kador PF, Kinoshita JH. Role of aldose reductase in the development of diabetes associated complications. Am J Med 1985; 79: 8-12.
    • (1985) Am J Med , vol.79 , pp. 8-12
    • Kador, P.F.1    Kinoshita, J.H.2
  • 15
    • 0023899991 scopus 로고
    • The role of aldose reductase in the development of diabetic complications
    • Kador PF. The role of aldose reductase in the development of diabetic complications. Med Res Rev 1988; 8: 325-352.
    • (1988) Med Res Rev , vol.8 , pp. 325-352
    • Kador, P.F.1
  • 16
    • 0030941732 scopus 로고    scopus 로고
    • Aldose reductase inhibition protects diabetic and non-diabetic rat hearts from ischemic injury
    • Ramasamy R et al. Aldose reductase inhibition protects diabetic and non-diabetic rat hearts from ischemic injury. Diabetes 1997; 46: 292-300.
    • (1997) Diabetes , vol.46 , pp. 292-300
    • Ramasamy, R.1
  • 17
    • 61949182565 scopus 로고    scopus 로고
    • Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore
    • Ananthakrishnan R et al. Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore. Am J Physiol Heart Circ Physiol 2009; 296: H333-H341.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Ananthakrishnan, R.1
  • 18
    • 33846089405 scopus 로고    scopus 로고
    • Cardiac ATP-sensitive potassium channels: A potential target for an anti-ischaemic pharmacological strategy
    • Testai L et al. Cardiac ATP-sensitive potassium channels: a potential target for an anti-ischaemic pharmacological strategy. Cardiovasc Hematol Agents Med Chem 2007; 5: 79-90.
    • (2007) Cardiovasc Hematol Agents Med Chem , vol.5 , pp. 79-90
    • Testai, L.1
  • 19
    • 0033711680 scopus 로고    scopus 로고
    • Aldose reductase inhibition alone or combined with an adenosine A(3) agonist reduces ischemic myocardial injury
    • Tracey WR et al. Aldose reductase inhibition alone or combined with an adenosine A(3) agonist reduces ischemic myocardial injury. Am J Physiol Heart Circ Physiol 2000; 279: H1447-H1452.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Tracey, W.R.1
  • 20
    • 0036482028 scopus 로고    scopus 로고
    • Aldose reductase activation is a key component of myocardial response to ischemia
    • Hwang YC et al. Aldose reductase activation is a key component of myocardial response to ischemia. FASEB J 2002; 16: 243-245.
    • (2002) FASEB J , vol.16 , pp. 243-245
    • Hwang, Y.C.1
  • 21
    • 3442890207 scopus 로고    scopus 로고
    • Central role for aldose reductase pathway in myocardial ischemic injury
    • Hwang YC et al. Central role for aldose reductase pathway in myocardial ischemic injury. FASEB J 2004; 18: 1192-1199.
    • (2004) FASEB J , vol.18 , pp. 1192-1199
    • Hwang, Y.C.1
  • 22
    • 0034851575 scopus 로고    scopus 로고
    • Therapeutic potential of antioxidants and diabetic retinopathy
    • Kowluru RA, Kennedy A. Therapeutic potential of antioxidants and diabetic retinopathy. Expert Opin Investig Drugs 2001; 10: 1665-1676.
    • (2001) Expert Opin Investig Drugs , vol.10 , pp. 1665-1676
    • Kowluru, R.A.1    Kennedy, A.2
  • 23
    • 0036657193 scopus 로고    scopus 로고
    • Neurovascular disease, antioxidants and glycation in diabetes
    • Dickinson PJ et al. Neurovascular disease, antioxidants and glycation in diabetes. Diabetes Metab Res Rev 2002; 18: 260-272.
    • (2002) Diabetes Metab Res Rev , vol.18 , pp. 260-272
    • Dickinson, P.J.1
  • 24
    • 34948815084 scopus 로고    scopus 로고
    • Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity
    • La Motta C et al. Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity. J Med Chem 2007; 50: 4917-4927.
    • (2007) J Med Chem , vol.50 , pp. 4917-4927
    • La Motta, C.1
  • 25
    • 70350345216 scopus 로고    scopus 로고
    • Anti-ischemic properties of a new spirocyclic benzopyran activator of the cardiac mito-K(ATP) channel
    • Calderone V et al. Anti-ischemic properties of a new spirocyclic benzopyran activator of the cardiac mito-K(ATP) channel. Biochem Pharmacol 2010; 79: 39-47.
    • Biochem Pharmacol , vol.2010 , Issue.79 , pp. 39-47
    • Calderone, V.1
  • 26
    • 18844369302 scopus 로고    scopus 로고
    • Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options
    • Srivastava SK et al. Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options. Endocr Rev 2005; 26: 380-392.
    • (2005) Endocr Rev , vol.26 , pp. 380-392
    • Srivastava, S.K.1
  • 27
    • 43049159358 scopus 로고    scopus 로고
    • Carboxymethilated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, portioning and molecular modeling
    • Stefek M et al. Carboxymethilated pyridoindole antioxidants as aldose reductase inhibitors: synthesis, activity, portioning and molecular modeling. Bioorg Med Chem 2009; 16: 4908-4920.
    • (2009) Bioorg Med Chem , vol.16 , pp. 4908-4920
    • Stefek, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.