Bicyclol attenuates pro-inflammatory cytokine and chemokine productions in CpG-DNA-stimulated L02 hepatocytes by inhibiting p65-NF-κB and p38-MAPK activation

Pharmazie

Volumn 65, Issue 3, 2010, Pages 206-212

  Lou, Xiao E ^a,c   Xu, Ning ^b,c   Yao, Hang Ping ^c   Chen, Zhi ^c  

^a ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BICYCLOL; CHEMOKINE; CPG OLIGODEOXYNUCLEOTIDE; CYTOKINE; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; RANTES; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROTECTION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; INFLAMMATION; LIVER CELL; SIGNAL TRANSDUCTION;

BIPHENYL COMPOUNDS; BLOTTING, WESTERN; CHEMOKINES; CPG ISLANDS; CYTOKINES; DNA; DNA, VIRAL; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HEPATOCYTES; HUMANS; INFLAMMATION; NUCLEAR PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; STIMULATION, CHEMICAL; TOLL-LIKE RECEPTOR 9; TRANSCRIPTION FACTOR RELA;

EID: 77949343910     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2010.9679     Document Type: Article

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