The rate-limiting catalytic steps of hydroxymandelate synthase from amycolatopsis Orientalise

Biochemistry

Volumn 49, Issue 9, 2010, Pages 1998-2007

  He, Panqing ^a   Conrad, John A ^a   Moran, Graham R ^a  

^a UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4-HYDROXYPHENYLPYRUVATE DIOXYGENASE; ANAEROBIC CONDITIONS; BENZYLIC; BENZYLIC CARBON; CHARGE-TRANSFER ABSORPTION; DISSOCIATION CONSTANT; KINETIC ISOTOPE EFFECTS; MIXING TIME; NONRIBOSOMAL PEPTIDE; OXYGEN ATOM; PHENYLGLYCINES; PRODUCT COMPLEX; RATE LIMITING; RATE-LIMITING STEPS; RELATIVE VALUE; SOLVENT ENVIRONMENTS; STEADY-STATE ANALYSIS; SYNTHASES; THIRD PHASE; VANCOMYCIN;

ANTIBIOTICS; DEUTERIUM; DISSOCIATION; HEAVY WATER; OXYGEN; PEPTIDES; PROTONS; SUBSTRATES;

RATE CONSTANTS;

4 HYDROXYPHENYLPYRUVIC ACID; BACTERIAL ENZYME; CARBON; DEUTERIUM; DEUTERIUM OXIDE; FERROUS ION; HYDROXYMANDELATE SYNTHASE; PROTON; PYRUVIC ACID DERIVATIVE; SYNTHETASE; UNCLASSIFIED DRUG;

ABSORPTION; ARTICLE; CATALYSIS; COMPLEX FORMATION; DISSOCIATION CONSTANT; ENZYME KINETICS; ENZYME SUBSTRATE; HYDROXYLATION; NOCARDIA ORIENTALIS; NONHUMAN; PH; PRIORITY JOURNAL; STEADY STATE; STREPTOMYCES; TITRIMETRY;

ACTINOMYCETALES; BACTERIAL PROTEINS; CATALYSIS; DEUTERIUM OXIDE; DIOXYGENASES; HYDROXYLATION; KINETICS; MANDELIC ACIDS; MODELS, CHEMICAL; OXYGEN CONSUMPTION; PHENYLPYRUVIC ACIDS; SUBSTRATE SPECIFICITY;

AMYCOLATOPSIS;

EID: 77749286320     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi901674q     Document Type: Article

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