메뉴 건너뛰기




Volumn 5, Issue 4, 2009, Pages 361-364

Editorial: The contribution of genetic studies in shifting the immunopathogenesis paradigm of Crohn's disease

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; PROBIOTIC AGENT; TUMOR NECROSIS FACTOR ALPHA INHIBITOR;

EID: 77649148700     PISSN: 1744666X     EISSN: None     Source Type: Journal    
DOI: 10.1586/eci.09.21     Document Type: Editorial
Times cited : (3)

References (31)
  • 2
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 448, 427-434 (2007).
    • (2007) Nature , vol.448 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 4
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 124, 783-801 (2006).
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 5
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • Cho JH. The genetics and immunopathogenesis of inflammatory bowel disease. Nat. Rev. Immunol. 8, 458-466 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 458-466
    • Cho, J.H.1
  • 6
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411, 603-606 (2001).
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3
  • 7
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot JP, Chamaillard M, Zouali H et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 411, 599-603 (2001).
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1    Chamaillard, M.2    Zouali, H.3
  • 8
    • 58149159542 scopus 로고    scopus 로고
    • Common variants in the NLRP3 region contribute to Crohn disease susceptibility
    • Villani AC, Lemire M, Fortin G et al. Common variants in the NLRP3 region contribute to Crohn disease susceptibility. Nat. Genet. 41, 71-76 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 71-76
    • Villani, A.C.1    Lemire, M.2    Fortin, G.3
  • 10
    • 27944464550 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
    • Yamazaki K, McGovern D, Ragoussis J et al. Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum. Mol. Genet. 14, 3499-3506 (2005).
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 3499-3506
    • Yamazaki, K.1    McGovern, D.2    Ragoussis, J.3
  • 11
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • Duerr RH, Taylor KD, Brant SR et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314, 1403-1405 (2006).
    • (2006) Science , vol.314 , pp. 1403-1405
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3
  • 13
    • 34347338690 scopus 로고    scopus 로고
    • Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
    • Parkes M, Barrett JC, Prescott NJ et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat. Genet. 39, 1045-1051 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 1045-1051
    • Parkes, M.1    Barrett, J.C.2    Prescott, N.J.3
  • 14
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678 (2007).
    • (2007) Nature , vol.447 , pp. 661-678
  • 15
    • 34247554965 scopus 로고    scopus 로고
    • Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
    • Rioux JD, Xavier RJ, Taylor KD et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat. Genet. 39, 596-604 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 596-604
    • Rioux, J.D.1    Xavier, R.J.2    Taylor, K.D.3
  • 16
    • 34247579326 scopus 로고    scopus 로고
    • Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
    • Libioulle C, Louis E, Hansoul S et al. Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet. 3, 538-543 (2007).
    • (2007) PLoS Genet. , vol.3 , pp. 538-543
    • Libioulle, C.1    Louis, E.2    Hansoul, S.3
  • 17
    • 37249034766 scopus 로고    scopus 로고
    • Systematic association mapping identifies NELL1 as a novel IBD disease gene
    • Franke A, Hampe J, Rosenstiel P et al. Systematic association mapping identifies NELL1 as a novel IBD disease gene. PLoS ONE 2, e691 (2007).
    • (2007) PLoS ONE , vol.2
    • Franke, A.1    Hampe, J.2    Rosenstiel, P.3
  • 18
    • 35548958718 scopus 로고    scopus 로고
    • Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci
    • Raelson JV, Little RD, Ruether A et al. Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci. Proc. Natl Acad. Sci. USA 104, 14747-14752 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 14747-14752
    • Raelson, J.V.1    Little, R.D.2    Ruether, A.3
  • 19
    • 48349136889 scopus 로고    scopus 로고
    • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
    • Barrett JC, Hansoul S, Nicolae DL et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat. Genet. 40, 955-962 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 955-962
    • Barrett, J.C.1    Hansoul, S.2    Nicolae, D.L.3
  • 20
    • 33344475671 scopus 로고    scopus 로고
    • Autophagy in innate and adaptive immunity against intracellular pathogens
    • Schmid D, Dengjel J, Schoor O, Stevanovic S, Münz C. Autophagy in innate and adaptive immunity against intracellular pathogens. J. Mol. Med. 84, 194-202 (2006).
    • (2006) J. Mol. Med. , vol.84 , pp. 194-202
    • Schmid, D.1    Dengjel, J.2    Schoor, O.3    Stevanovic, S.4    Münz, C.5
  • 21
    • 44349136821 scopus 로고    scopus 로고
    • Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
    • Fisher SA, Tremelling M, Anderson CA et al. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat. Genet. 40, 710-712 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 710-712
    • Fisher, S.A.1    Tremelling, M.2    Anderson, C.A.3
  • 22
    • 44349173654 scopus 로고    scopus 로고
    • Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
    • Franke A, Balschun T, Karlsen TH et al. Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat. Genet. 40, 713-715 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 713-715
    • Franke, A.1    Balschun, T.2    Karlsen, T.H.3
  • 23
    • 40049111515 scopus 로고    scopus 로고
    • Treatment of inflammatory bowel disease: A review of medical therapy
    • Kozuch PL, Hanauer SB. Treatment of inflammatory bowel disease: a review of medical therapy. World J. Gastroenterol. 14, 354-377 (2008).
    • (2008) World J. Gastroenterol. , vol.14 , pp. 354-377
    • Kozuch, P.L.1    Hanauer, S.B.2
  • 24
    • 53149138268 scopus 로고    scopus 로고
    • Probiotics in the treatment of human inflammatory bowel diseases: Update
    • Fedorak RN, Dieleman LA. Probiotics in the treatment of human inflammatory bowel diseases: update 2008. J. Clin. Gastroenterol. 42, S97-S103 (2008).
    • (2008) J. Clin Gastroenterol. , vol.42
    • Fedorak, R.N.1    Dieleman, L.A.2
  • 26
    • 50249087428 scopus 로고    scopus 로고
    • A meta-analysis on the efficacy of probiotics for maintenance of remission and prevention of clinical and endoscopic relapse in Crohn's disease
    • Rahimi R, Nikfar S, Rahimi F et al. A meta-analysis on the efficacy of probiotics for maintenance of remission and prevention of clinical and endoscopic relapse in Crohn's disease. Dig. Dis. Sci. 53, 2524-2531 (2008).
    • (2008) Dig. Dis. Sci. , vol.53 , pp. 2524-2531
    • Rahimi, R.1    Nikfar, S.2    Rahimi, F.3
  • 27
    • 0033870413 scopus 로고    scopus 로고
    • Saccharomyces boulardii in maintenance treatment of Crohn's disease
    • Guslandi M, Mezzi G, Sorghi M, Testoni PA. Saccharomyces boulardii in maintenance treatment of Crohn's disease. Dig. Dis. Sci. 45, 1462-1464 (2000).
    • (2000) Dig. Dis. Sci. , vol.45 , pp. 1462-1464
    • Guslandi, M.1    Mezzi, G.2    Sorghi, M.3    Testoni, P.A.4
  • 28
    • 0036716855 scopus 로고    scopus 로고
    • Ineffectiveness of probiotics in preventing recurrence after curative resection for Crohn's disease: A randomised controlled trial with Lactobacillus GG
    • Prantera C, Scribano ML, Falasco G, Andreoli A, Luzi C. Ineffectiveness of probiotics in preventing recurrence after curative resection for Crohn's disease: a randomised controlled trial with Lactobacillus GG. Gut 51, 405-409 (2002).
    • (2002) Gut , vol.51 , pp. 405-409
    • Prantera, C.1    Scribano, M.L.2    Falasco, G.3    Andreoli, A.4    Luzi, C.5
  • 29
    • 25444512029 scopus 로고    scopus 로고
    • A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease
    • Bousvaros A, Guandalini S, Baldassano RN et al. A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease. Inflamm. Bowel Dis. 11, 833-839 (2005).
    • (2005) Inflamm. Bowel Dis. , vol.11 , pp. 833-839
    • Bousvaros, A.1    Guandalini, S.2    Baldassano, R.N.3
  • 30
    • 33646756180 scopus 로고    scopus 로고
    • Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn's disease: A randomised, double-blind, placebocontrolled GETAID trial
    • Marteau P, Lemann M, Seksik P et al. Ineffectiveness of Lactobacillus johnsonii LA1 for prophylaxis of postoperative recurrence in Crohn's disease: a randomised, double-blind, placebocontrolled GETAID trial. Gut 55, 842-847 (2006).
    • (2006) Gut , vol.55 , pp. 842-847
    • Marteau, P.1    Lemann, M.2    Seksik, P.3
  • 31
    • 34249341111 scopus 로고    scopus 로고
    • Multicenter randomized-controlled clinical trial of probiotics (Lactobacillus johnsonii, LA1) on early endoscopic recurrence of Crohn's disease after lleo caecal resection
    • Van Gossum A, Dewit O, Louis E et al. Multicenter randomized-controlled clinical trial of probiotics (Lactobacillus johnsonii, LA1) on early endoscopic recurrence of Crohn's disease after lleo caecal resection. Inflamm. Bowel Dis. 13, 135-142 (2007)
    • (2007) Inflamm. Bowel Dis. , vol.13 , pp. 135-142
    • Van Gossum, A.1    Dewit, O.2    Louis, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.