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Volumn 84, Issue 6, 2010, Pages 2740-2752

Evolution of the HIV-1 env gene in the Rag2-/- γC -/- humanized mouse model

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; EPITOPE; RAG2 PROTEIN; VIRUS DNA;

EID: 77649099626     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02180-09     Document Type: Article
Times cited : (39)

References (103)
  • 1
    • 34248335883 scopus 로고    scopus 로고
    • Use of a novel chimeric mouse model with a functionally active human immune system to study human immunodeficiency virus type 1 infection
    • An, D. S., B. Poon, R. H. T. Fang, K. Weijer, B. Blom, H. Spits, I. S. Chen, and C. H. Uittenbogaart. 2007. Use of a novel chimeric mouse model with a functionally active human immune system to study human immunodeficiency virus type 1 infection. Clin. Vaccine Immunol. 14:391-396.
    • (2007) Clin. Vaccine Immunol , vol.14 , pp. 391-396
    • An, D.S.1    Poon, B.2    Fang, R.H.T.3    Weijer, K.4    Blom, B.5    Spits, H.6    Chen, I.S.7    Uittenbogaart, C.H.8
  • 4
    • 2442671600 scopus 로고    scopus 로고
    • Increased sensitivity to CD4 binding site-directed neutralization following in vitro propagation on primary lymphocytes of a neutralization-resistant human immunodeficiency virus IIIB strain isolated from an accidentally infected laboratory worker
    • Beaumont, T., E. Quakkelaar, A. van Nuenen, R. Pantophlet, and H. Schuitemaker. 2004. Increased sensitivity to CD4 binding site-directed neutralization following in vitro propagation on primary lymphocytes of a neutralization-resistant human immunodeficiency virus IIIB strain isolated from an accidentally infected laboratory worker. J. Virol. 78:5651-5657.
    • (2004) J. Virol , vol.78 , pp. 5651-5657
    • Beaumont, T.1    Quakkelaar, E.2    van Nuenen, A.3    Pantophlet, R.4    Schuitemaker, H.5
  • 9
    • 0033961745 scopus 로고    scopus 로고
    • In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline
    • Blaak, H., A. B. van't Wout, M. Brouwer, B. Hooibrink, E. Hovenkamp, and H. Schuitemaker. 2000. In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline. Proc. Natl. Acad. Sci. USA 97: 1269-1274.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1269-1274
    • Blaak, H.1    van't Wout, A.B.2    Brouwer, M.3    Hooibrink, B.4    Hovenkamp, E.5    Schuitemaker, H.6
  • 10
    • 30344476119 scopus 로고    scopus 로고
    • Consistent patterns of change during the divergence of human immunodeficiency virus type 1 envelope from that of the inoculated virus in simian/human immunodeficiency virus-infected macaques
    • Blay, W. M., S. Gnanakaran, B. Foley, N. A. Doria-Rose, B. T. Korber, and N. L. Haigwood. 2006. Consistent patterns of change during the divergence of human immunodeficiency virus type 1 envelope from that of the inoculated virus in simian/human immunodeficiency virus-infected macaques. J. Virol. 80:999-1014.
    • (2006) J. Virol , vol.80 , pp. 999-1014
    • Blay, W.M.1    Gnanakaran, S.2    Foley, B.3    Doria-Rose, N.A.4    Korber, B.T.5    Haigwood, N.L.6
  • 11
    • 0031444234 scopus 로고    scopus 로고
    • Anti-human immunodeficiency virus type 1 human monoclonal antibodies that bind discontinuous epitopes in the viral glycoproteins can identify mimotopes from recombinant phage peptide display libraries
    • Boots, L. J., P. M. McKenna, B. A. Arnold, P. M. Keller, M. K. Gorny, S. Zolla-Pazner, J. E. Robinson, and A. J. Conley. 1997. Anti-human immunodeficiency virus type 1 human monoclonal antibodies that bind discontinuous epitopes in the viral glycoproteins can identify mimotopes from recombinant phage peptide display libraries. AIDS Res. Hum. Retrovir. 13:1549-1559.
    • (1997) AIDS Res. Hum. Retrovir , vol.13 , pp. 1549-1559
    • Boots, L.J.1    McKenna, P.M.2    Arnold, B.A.3    Keller, P.M.4    Gorny, M.K.5    Zolla-Pazner, S.6    Robinson, J.E.7    Conley, A.J.8
  • 12
    • 16944365445 scopus 로고    scopus 로고
    • Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
    • Borrow, P., H. Lewicki, X. Wei, M. S. Horwitz, N. Peffer, H. Meyers, J. A. Nelson, J. E. Gairin, B. H. Hahn, M. B. Oldstone, and G. M. Shaw. 1997. Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nat. Med. 3:205-211.
    • (1997) Nat. Med , vol.3 , pp. 205-211
    • Borrow, P.1    Lewicki, H.2    Wei, X.3    Horwitz, M.S.4    Peffer, N.5    Meyers, H.6    Nelson, J.A.7    Gairin, J.E.8    Hahn, B.H.9    Oldstone, M.B.10    Shaw, G.M.11
  • 13
    • 0004732896 scopus 로고    scopus 로고
    • Analysis of HIV-1 env gene sequences reveals evidence for a low effective number in the viral population
    • Brown, A. J. 1997. Analysis of HIV-1 env gene sequences reveals evidence for a low effective number in the viral population. Proc. Natl. Acad. Sci. USA 94:1862-1865.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1862-1865
    • Brown, A.J.1
  • 14
    • 33846071114 scopus 로고    scopus 로고
    • Increased neutralization sensitivity of recently emerged CXCR4-using human immunodeficiency virus type 1 strains compared to coexisting CCR5-using variants from the same patient
    • Bunnik, E. M., E. D. Quakkelaar, A. C. van Nuenen, B. Boeser-Nummink, and H. Schuitemaker. 2007. Increased neutralization sensitivity of recently emerged CXCR4-using human immunodeficiency virus type 1 strains compared to coexisting CCR5-using variants from the same patient. J. Virol. 81:525-531.
    • (2007) J. Virol , vol.81 , pp. 525-531
    • Bunnik, E.M.1    Quakkelaar, E.D.2    van Nuenen, A.C.3    Boeser-Nummink, B.4    Schuitemaker, H.5
  • 15
    • 0030842609 scopus 로고    scopus 로고
    • Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies
    • Chackerian, B., L. M. Rudensey, and J. Overbaugh. 1997. Specific N-linked and O-linked glycosylation modifications in the envelope V1 domain of simian immunodeficiency virus variants that evolve in the host alter recognition by neutralizing antibodies. J. Virol. 71:7719-7727.
    • (1997) J. Virol , vol.71 , pp. 7719-7727
    • Chackerian, B.1    Rudensey, L.M.2    Overbaugh, J.3
  • 18
    • 0027409934 scopus 로고
    • Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals
    • Connor, R. I., H. Mohri, Y. Cao, and D. D. Ho. 1993. Increased viral burden and cytopathicity correlate temporally with CD4+ T-lymphocyte decline and clinical progression in human immunodeficiency virus type 1-infected individuals. J. Virol. 67:1772-1777.
    • (1993) J. Virol , vol.67 , pp. 1772-1777
    • Connor, R.I.1    Mohri, H.2    Cao, Y.3    Ho, D.D.4
  • 19
    • 0031575431 scopus 로고    scopus 로고
    • Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
    • Connor, R. I., K. E. Sheridan, D. Ceradini, S. Choe, and N. R. Landau. 1997. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J. Exp. Med. 185:621-628.
    • (1997) J. Exp. Med , vol.185 , pp. 621-628
    • Connor, R.I.1    Sheridan, K.E.2    Ceradini, D.3    Choe, S.4    Landau, N.R.5
  • 20
    • 0031975192 scopus 로고    scopus 로고
    • Delwart, E. L., J. I. Mullins, P. Gupta, G. H. Learn, Jr., M. Holodniy, D. Katzenstein, B. D. Walker, and M. K. Singh. 1998. Human immunodeficiency virus type 1 populations in blood and semen. J. Virol. 72:617-623.
    • Delwart, E. L., J. I. Mullins, P. Gupta, G. H. Learn, Jr., M. Holodniy, D. Katzenstein, B. D. Walker, and M. K. Singh. 1998. Human immunodeficiency virus type 1 populations in blood and semen. J. Virol. 72:617-623.
  • 22
    • 61449091512 scopus 로고    scopus 로고
    • Novel humanized murine models for HIV research. Curr
    • Denton, P. W., and J. V. Garcia. 2009. Novel humanized murine models for HIV research. Curr. HIV/AIDS Rep. 6:13-19.
    • (2009) HIV/AIDS Rep , vol.6 , pp. 13-19
    • Denton, P.W.1    Garcia, J.V.2
  • 23
    • 34548680527 scopus 로고    scopus 로고
    • Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementia
    • Dunfee, R. L., E. R. Thomas, J. Wang, K. Kunstman, S. M. Wolinsky, and D. Gabuzda. 2007. Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementia. Virology 367:222-234.
    • (2007) Virology , vol.367 , pp. 222-234
    • Dunfee, R.L.1    Thomas, E.R.2    Wang, J.3    Kunstman, K.4    Wolinsky, S.M.5    Gabuzda, D.6
  • 24
    • 0026709367 scopus 로고
    • Efficient amplification of HIV half-genomes from tissue DNA
    • Edmonson, P. F., and J. I. Mullins. 1992. Efficient amplification of HIV half-genomes from tissue DNA. Nucleic Acids Res. 20:4933.
    • (1992) Nucleic Acids Res , vol.20 , pp. 4933
    • Edmonson, P.F.1    Mullins, J.I.2
  • 26
    • 0026606727 scopus 로고
    • Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule
    • Fouchier, R. A., M. Groenink, N. A. Kootstra, M. Tersmette, H. G. Huisman, F. Miedema, and H. Schuitemaker. 1992. Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule. J. Virol. 66:3183-3187.
    • (1992) J. Virol , vol.66 , pp. 3183-3187
    • Fouchier, R.A.1    Groenink, M.2    Kootstra, N.A.3    Tersmette, M.4    Huisman, H.G.5    Miedema, F.6    Schuitemaker, H.7
  • 28
    • 3242732993 scopus 로고    scopus 로고
    • Compartmentalization of human immunodeficiency virus type 1 between blood monocytes and CD4+ T cells during infection
    • Fulcher, J. A., Y. Hwangbo, R. Zioni, D. Nickle, X. Lin, L. Heath, J. I. Mullins, L. Corey, and T. Zhu. 2004. Compartmentalization of human immunodeficiency virus type 1 between blood monocytes and CD4+ T cells during infection. J. Virol. 78:7883-7893.
    • (2004) J. Virol , vol.78 , pp. 7883-7893
    • Fulcher, J.A.1    Hwangbo, Y.2    Zioni, R.3    Nickle, D.4    Lin, X.5    Heath, L.6    Mullins, J.I.7    Corey, L.8    Zhu, T.9
  • 29
    • 0025367812 scopus 로고
    • Sequence differences between glycosylated and non-glycosylated Asn-X-Thr/Ser acceptor sites: Implications for protein engineering
    • Gavel, Y., and G. von Heijne. 1990. Sequence differences between glycosylated and non-glycosylated Asn-X-Thr/Ser acceptor sites: implications for protein engineering. Protein Eng. 3:433-442.
    • (1990) Protein Eng , vol.3 , pp. 433-442
    • Gavel, Y.1    von Heijne, G.2
  • 31
    • 0142092389 scopus 로고    scopus 로고
    • Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
    • Guadalupe, M., E. Reay, S. Sankaran, T. Prindiville, J. Flamm, A. McNeil, and S. Dandekar. 2003. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J. Virol. 77:11708-11717.
    • (2003) J. Virol , vol.77 , pp. 11708-11717
    • Guadalupe, M.1    Reay, E.2    Sankaran, S.3    Prindiville, T.4    Flamm, J.5    McNeil, A.6    Dandekar, S.7
  • 32
    • 0141703218 scopus 로고    scopus 로고
    • CD8+ T cell-mediated CXC chemokine receptor 4-simian/human immunodeficiency virus suppression in dually infected rhesus macaques
    • Harouse, J. M., C. Buckner, A. Gettie, R. Fuller, R. Bohm, J. Blanchard, and C. Cheng-Mayer. 2003. CD8+ T cell-mediated CXC chemokine receptor 4-simian/human immunodeficiency virus suppression in dually infected rhesus macaques. Proc. Natl. Acad. Sci. USA 100:10977-10982.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 10977-10982
    • Harouse, J.M.1    Buckner, C.2    Gettie, A.3    Fuller, R.4    Bohm, R.5    Blanchard, J.6    Cheng-Mayer, C.7
  • 33
    • 35348922244 scopus 로고    scopus 로고
    • Dynamics of simian immunodeficiency virus populations in blood and cerebrospinal fluid over the full course of infection
    • Harrington, P. R., M. J. Connell, R. B. Meeker, P. R. Johnson, and R. Swanstrom. 2007. Dynamics of simian immunodeficiency virus populations in blood and cerebrospinal fluid over the full course of infection. J. Infect. Dis. 196:1058-1067.
    • (2007) J. Infect. Dis , vol.196 , pp. 1058-1067
    • Harrington, P.R.1    Connell, M.J.2    Meeker, R.B.3    Johnson, P.R.4    Swanstrom, R.5
  • 34
    • 0028853961 scopus 로고
    • Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
    • He, J., S. Choe, R. Walker, P. Di Marzio, D. O. Morgan, and N. R. Landau. 1995. Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity. J. Virol. 69:6705-6711.
    • (1995) J. Virol , vol.69 , pp. 6705-6711
    • He, J.1    Choe, S.2    Walker, R.3    Di Marzio, P.4    Morgan, D.O.5    Landau, N.R.6
  • 36
    • 34547731884 scopus 로고    scopus 로고
    • Coreceptor switch in R5-tropic simian/human immunodeficiency virus-infected macaques
    • Ho, S. H., S. Tasca, L. Shek, A. Li, A. Gettie, J. Blanchard, D. Boden, and C. Cheng-Mayer. 2007. Coreceptor switch in R5-tropic simian/human immunodeficiency virus-infected macaques. J. Virol. 81:8621-8633.
    • (2007) J. Virol , vol.81 , pp. 8621-8633
    • Ho, S.H.1    Tasca, S.2    Shek, L.3    Li, A.4    Gettie, A.5    Blanchard, J.6    Boden, D.7    Cheng-Mayer, C.8
  • 37
    • 57349129555 scopus 로고    scopus 로고
    • -/- mice transplanted with CD34+ cells from human cord blood show low levels of intestinal engraftment and are resistant to rectal transmission of human immunodeficiency virus
    • -/- mice transplanted with CD34+ cells from human cord blood show low levels of intestinal engraftment and are resistant to rectal transmission of human immunodeficiency virus. J. Virol. 82:12145-12153.
    • (2008) J. Virol , vol.82 , pp. 12145-12153
    • Hofer, U.1    Baenziger, S.2    Heikenwalder, M.3    Schlaepfer, E.4    Gehre, N.5    Regenass, S.6    Brunner, T.7    Speck, R.F.8
  • 39
    • 66149133580 scopus 로고    scopus 로고
    • Major coexisting human immunodeficiency virus type 1 env gene subpopulations in the peripheral blood are produced by cells with similar turnover rates and show little evidence of genetic compartmentalization
    • Ince, W. L., P. R. Harrington, G. L. Schnell, M. Patel-Chhabra, C. L. Burch, P. Menezes, R. W. Price, J. J. Eron, Jr., and R. I. Swanstrom. 2009. Major coexisting human immunodeficiency virus type 1 env gene subpopulations in the peripheral blood are produced by cells with similar turnover rates and show little evidence of genetic compartmentalization. J. Virol. 83:4068-4080.
    • (2009) J. Virol , vol.83 , pp. 4068-4080
    • Ince, W.L.1    Harrington, P.R.2    Schnell, G.L.3    Patel-Chhabra, M.4    Burch, C.L.5    Menezes, P.6    Price, R.W.7    Eron Jr., J.J.8    Swanstrom, R.I.9
  • 41
    • 10744231634 scopus 로고    scopus 로고
    • Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences
    • Jensen, M. A., F. S. Li, A. B. van't Wout, D. C. Nickle, D. Shriner, H. X. He, S. McLaughlin, R. Shankarappa, J. B. Margolick, and J. I. Mullins. 2003. Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences. J. Virol. 77:13376-13388.
    • (2003) J. Virol , vol.77 , pp. 13376-13388
    • Jensen, M.A.1    Li, F.S.2    van't Wout, A.B.3    Nickle, D.C.4    Shriner, D.5    He, H.X.6    McLaughlin, S.7    Shankarappa, R.8    Margolick, J.B.9    Mullins, J.I.10
  • 42
    • 66349132212 scopus 로고    scopus 로고
    • Jern, P., R. A. Russell, V. K. Pathak, and J. M. Coffin. 2009. Likely role of APOBEC3G-mediated G-to-A mutations in HIV-1 evolution and drug resistance. PLoS Pathog. 5:e1000367.
    • Jern, P., R. A. Russell, V. K. Pathak, and J. M. Coffin. 2009. Likely role of APOBEC3G-mediated G-to-A mutations in HIV-1 evolution and drug resistance. PLoS Pathog. 5:e1000367.
  • 44
    • 45949107473 scopus 로고    scopus 로고
    • Recent developments in the MAFFT multiple sequence alignment program
    • Katoh, K., and H. Toh. 2008. Recent developments in the MAFFT multiple sequence alignment program. Brief. Bioinform. 9:286-298.
    • (2008) Brief. Bioinform , vol.9 , pp. 286-298
    • Katoh, K.1    Toh, H.2
  • 45
    • 44649102135 scopus 로고    scopus 로고
    • Keele, B. F., E. E. Giorgi, J. F. Salazar-Gonzalez, J. M. Decker, K. T. Pham, M. G. Salazar, C. Sun, T. Grayson, S. Wang, H. Li, X. Wei, C. Jiang, J. L. Kirchherr, F. Gao, J. A. Anderson, L. H. Ping, R. Swanstrom, G. D. Tomaras, W. A. Blattner, P. A. Goepfert, J. M. Kilby, M. S. Saag, E. L. Delwart, M. P. Busch, M. S. Cohen, D. C. Montefiori, B. F. Haynes, B. Gaschen, G. S. Athreya, H. Y. Lee, N. Wood, C. Seoighe, A. S. Perelson, T. Bhattacharya, B. T. Korber, B. H. Hahn, and G. M. Shaw. 2008. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc. Natl. Acad. Sci. USA 105:7552-7557.
    • Keele, B. F., E. E. Giorgi, J. F. Salazar-Gonzalez, J. M. Decker, K. T. Pham, M. G. Salazar, C. Sun, T. Grayson, S. Wang, H. Li, X. Wei, C. Jiang, J. L. Kirchherr, F. Gao, J. A. Anderson, L. H. Ping, R. Swanstrom, G. D. Tomaras, W. A. Blattner, P. A. Goepfert, J. M. Kilby, M. S. Saag, E. L. Delwart, M. P. Busch, M. S. Cohen, D. C. Montefiori, B. F. Haynes, B. Gaschen, G. S. Athreya, H. Y. Lee, N. Wood, C. Seoighe, A. S. Perelson, T. Bhattacharya, B. T. Korber, B. H. Hahn, and G. M. Shaw. 2008. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc. Natl. Acad. Sci. USA 105:7552-7557.
  • 47
    • 0041920924 scopus 로고    scopus 로고
    • Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition
    • Koch, M., M. Pancera, P. D. Kwong, P. Kolchinsky, C. Grundner, L. Wang, W. A. Hendrickson, J. Sodroski, and R. Wyatt. 2003. Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition. Virology 313:387-400.
    • (2003) Virology , vol.313 , pp. 387-400
    • Koch, M.1    Pancera, M.2    Kwong, P.D.3    Kolchinsky, P.4    Grundner, C.5    Wang, L.6    Hendrickson, W.A.7    Sodroski, J.8    Wyatt, R.9
  • 48
    • 0035131175 scopus 로고    scopus 로고
    • Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants
    • Kolchinsky, P., E. Kiprilov, and J. Sodroski. 2001. Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants. J. Virol. 75:2041-2050.
    • (2001) J. Virol , vol.75 , pp. 2041-2050
    • Kolchinsky, P.1    Kiprilov, E.2    Sodroski, J.3
  • 49
    • 0032929247 scopus 로고    scopus 로고
    • Conversion rate towards a syncytium-inducing (SI) phenotype during different stages of human immunodeficiency virus type 1 infection and prognostic value of SI phenotype for survival after AIDS diagnosis
    • Koot, M., R. van Leeuwen, R. E. de Goede, I. P. Keet, S. Danner, J. K. Eeftinck Schattenkerk, P. Reiss, M. Tersmette, J. M. Lange, and H. Schuitemaker. 1999. Conversion rate towards a syncytium-inducing (SI) phenotype during different stages of human immunodeficiency virus type 1 infection and prognostic value of SI phenotype for survival after AIDS diagnosis. J. Infect. Dis. 179:254-258.
    • (1999) J. Infect. Dis , vol.179 , pp. 254-258
    • Koot, M.1    van Leeuwen, R.2    de Goede, R.E.3    Keet, I.P.4    Danner, S.5    Eeftinck Schattenkerk, J.K.6    Reiss, P.7    Tersmette, M.8    Lange, J.M.9    Schuitemaker, H.10
  • 50
    • 77649136023 scopus 로고    scopus 로고
    • Korber, B. 2000. HIV signature and sequence variation analysis, p. 55-72. In A. G. Rodrigo and G. H. Learn, Jr. (ed.), Computational and evolutionary analysis of HIV molecular sequences. Kluwer Academic Publishers, Dordrecht, The Netherlands.
    • Korber, B. 2000. HIV signature and sequence variation analysis, p. 55-72. In A. G. Rodrigo and G. H. Learn, Jr. (ed.), Computational and evolutionary analysis of HIV molecular sequences. Kluwer Academic Publishers, Dordrecht, The Netherlands.
  • 51
    • 0028046638 scopus 로고
    • Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: Evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences
    • Korber, B. T., K. J. Kunstman, B. K. Patterson, M. Furtado, M. M. McEvilly, R. Levy, and S. M. Wolinsky. 1994. Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences. J. Virol. 68: 7467-7481.
    • (1994) J. Virol , vol.68 , pp. 7467-7481
    • Korber, B.T.1    Kunstman, K.J.2    Patterson, B.K.3    Furtado, M.4    McEvilly, M.M.5    Levy, R.6    Wolinsky, S.M.7
  • 52
    • 0023214674 scopus 로고
    • Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms
    • Koyanagi, Y., S. Miles, R. T. Mitsuyasu, J. E. Merrill, H. V. Vinters, and I. S. Chen. 1987. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 236:819-822.
    • (1987) Science , vol.236 , pp. 819-822
    • Koyanagi, Y.1    Miles, S.2    Mitsuyasu, R.T.3    Merrill, J.E.4    Vinters, H.V.5    Chen, I.S.6
  • 54
    • 65549140728 scopus 로고    scopus 로고
    • HIV-1 entry inhibitors: An overview
    • Kuritzkes, D. R. 2009. HIV-1 entry inhibitors: an overview. Curr. Opin. HIV AIDS 4:82-87.
    • (2009) Curr. Opin. HIV AIDS , vol.4 , pp. 82-87
    • Kuritzkes, D.R.1
  • 55
    • 0013259304 scopus 로고    scopus 로고
    • DAB(389)IL-2 (denileukin diftitox, ONTAK): Other potential applications
    • LeMaistre, C. F. 2000. DAB(389)IL-2 (denileukin diftitox, ONTAK): other potential applications. Clin. Lymphoma 1(Suppl. 1):S37-S40.
    • (2000) Clin. Lymphoma , vol.1 , Issue.SUPPL. 1
    • LeMaistre, C.F.1
  • 57
    • 0027535672 scopus 로고
    • Glycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 binding
    • Li, Y., L. Luo, N. Rasool, and C. Y. Kang. 1993. Glycosylation is necessary for the correct folding of human immunodeficiency virus gp120 in CD4 binding. J. Virol. 67:584-588.
    • (1993) J. Virol , vol.67 , pp. 584-588
    • Li, Y.1    Luo, L.2    Rasool, N.3    Kang, C.Y.4
  • 58
    • 65649117685 scopus 로고    scopus 로고
    • DnaSP v5: A software for comprehensive analysis of DNA polymorphism data
    • Librado, P., and J. Rozas. 2009. DnaSP v5: a software for comprehensive analysis of DNA polymorphism data. Bioinformatics 25:1451-1452.
    • (2009) Bioinformatics , vol.25 , pp. 1451-1452
    • Librado, P.1    Rozas, J.2
  • 59
    • 0038681023 scopus 로고    scopus 로고
    • Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts
    • Mangeat, B., P. Turelli, G. Caron, M. Friedli, L. Perrin, and D. Trono. 2003. Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. Nature 424:99-103.
    • (2003) Nature , vol.424 , pp. 99-103
    • Mangeat, B.1    Turelli, P.2    Caron, G.3    Friedli, M.4    Perrin, L.5    Trono, D.6
  • 61
    • 0034904098 scopus 로고    scopus 로고
    • Effect of soluble CD4 on exposure of epitopes on primary, intact, native human immunodeficiency virus type 1 virions of different genetic clades
    • Mbah, H. A., S. Burda, M. K. Gorny, C. Williams, K. Revesz, S. Zolla-Pazner, and P. N. Nyambi. 2001. Effect of soluble CD4 on exposure of epitopes on primary, intact, native human immunodeficiency virus type 1 virions of different genetic clades. J. Virol. 75:7785-7788.
    • (2001) J. Virol , vol.75 , pp. 7785-7788
    • Mbah, H.A.1    Burda, S.2    Gorny, M.K.3    Williams, C.4    Revesz, K.5    Zolla-Pazner, S.6    Nyambi, P.N.7
  • 63
    • 0031455910 scopus 로고    scopus 로고
    • Patterns of amino acid variability in NSI-like and SI-like V3 sequences and a linked change in the CD4-binding domain of the HIV-1 Env protein
    • Milich, L., B. H. Margolin, and R. Swanstrom. 1997. Patterns of amino acid variability in NSI-like and SI-like V3 sequences and a linked change in the CD4-binding domain of the HIV-1 Env protein. Virology 239:108-118.
    • (1997) Virology , vol.239 , pp. 108-118
    • Milich, L.1    Margolin, B.H.2    Swanstrom, R.3
  • 64
    • 0030744820 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody IgG1b12
    • Mo, H. M., L. Stamatatos, J. E. Ip, C. F. Barbas, P. Parren, D. R. Burton, J. P. Moore, and D. D. Ho. 1997. Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody IgG1b12. J. Virol. 71:6869-6874.
    • (1997) J. Virol , vol.71 , pp. 6869-6874
    • Mo, H.M.1    Stamatatos, L.2    Ip, J.E.3    Barbas, C.F.4    Parren, P.5    Burton, D.R.6    Moore, J.P.7    Ho, D.D.8
  • 65
    • 0028917784 scopus 로고
    • Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120
    • Moore, J. P., Y. Cao, L. Qing, Q. J. Sattentau, J. Pyati, R. Koduri, J. Robinson, C. F. Barbas III, D. R. Burton, and D. D. Ho. 1995. Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120. J. Virol. 69:101-109.
    • (1995) J. Virol , vol.69 , pp. 101-109
    • Moore, J.P.1    Cao, Y.2    Qing, L.3    Sattentau, Q.J.4    Pyati, J.5    Koduri, R.6    Robinson, J.7    Barbas III, C.F.8    Burton, D.R.9    Ho, D.D.10
  • 66
    • 0005000433 scopus 로고
    • HIV-1 neutralization: The consequences of viral adaptation to growth on transformed T cells
    • Moore, J. P., and D. D. Ho. 1995. HIV-1 neutralization: the consequences of viral adaptation to growth on transformed T cells. AIDS 9(Suppl. A): S117-S136.
    • (1995) AIDS , vol.9 , Issue.SUPPL. A
    • Moore, J.P.1    Ho, D.D.2
  • 67
    • 0022507362 scopus 로고
    • Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions
    • Nei, M., and T. Gojobori. 1986. Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol. Biol. Evol. 3:418-426.
    • (1986) Mol. Biol. Evol , vol.3 , pp. 418-426
    • Nei, M.1    Gojobori, T.2
  • 68
    • 0033865498 scopus 로고    scopus 로고
    • Patterns of changes in human immunodeficiency virus type 1 V3 sequence populations late in infection
    • Nelson, J. A., F. Baribaud, T. Edwards, and R. Swanstrom. 2000. Patterns of changes in human immunodeficiency virus type 1 V3 sequence populations late in infection. J. Virol. 74:8494-8501.
    • (2000) J. Virol , vol.74 , pp. 8494-8501
    • Nelson, J.A.1    Baribaud, F.2    Edwards, T.3    Swanstrom, R.4
  • 69
    • 0028286120 scopus 로고
    • Variance and covariances of the numbers of synonymous and nonsynonymous substitutions per site
    • Ota, T., and M. Nei. 1994. Variance and covariances of the numbers of synonymous and nonsynonymous substitutions per site. Mol. Biol. Evol. 11:613-619.
    • (1994) Mol. Biol. Evol , vol.11 , pp. 613-619
    • Ota, T.1    Nei, M.2
  • 71
    • 37849007568 scopus 로고    scopus 로고
    • Subtype-specific conformational differences within the V3 region of subtype B and subtype C human immunodeficiency virus type 1 Env proteins
    • Patel, M. B., N. G. Hoffman, and R. Swanstrom. 2008. Subtype-specific conformational differences within the V3 region of subtype B and subtype C human immunodeficiency virus type 1 Env proteins. J. Virol. 82:903-916.
    • (2008) J. Virol , vol.82 , pp. 903-916
    • Patel, M.B.1    Hoffman, N.G.2    Swanstrom, R.3
  • 72
    • 0031954686 scopus 로고    scopus 로고
    • Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1
    • Platt, E. J., K. Wehrly, S. E. Kuhmann, B. Chesebro, and D. Kabat. 1998. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J. Virol. 72:2855-2864.
    • (1998) J. Virol , vol.72 , pp. 2855-2864
    • Platt, E.J.1    Wehrly, K.2    Kuhmann, S.E.3    Chesebro, B.4    Kabat, D.5
  • 73
    • 0035918220 scopus 로고    scopus 로고
    • N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization
    • Pollakis, G., S. Kang, A. Kliphuis, M. I. Chalaby, J. Goudsmit, and W. A. Paxton. 2001. N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization. J. Biol. Chem. 276:13433-13441.
    • (2001) J. Biol. Chem , vol.276 , pp. 13433-13441
    • Pollakis, G.1    Kang, S.2    Kliphuis, A.3    Chalaby, M.I.4    Goudsmit, J.5    Paxton, W.A.6
  • 74
    • 33846501408 scopus 로고    scopus 로고
    • Evolutionary interactions between N-linked glycosylation sites in the HIV-1 envelope
    • Poon, A. F., F. I. Lewis, S. L. Pond, and S. D. Frost. 2007. Evolutionary interactions between N-linked glycosylation sites in the HIV-1 envelope. PLoS Comput. Biol. 3:e11.
    • (2007) PLoS Comput. Biol , vol.3
    • Poon, A.F.1    Lewis, F.I.2    Pond, S.L.3    Frost, S.D.4
  • 75
    • 0031773680 scopus 로고    scopus 로고
    • MODELTEST: Testing the model of DNA substitution
    • Posada, D., and K. A. Crandall. 1998. MODELTEST: testing the model of DNA substitution. Bioinformatics 14:817-818.
    • (1998) Bioinformatics , vol.14 , pp. 817-818
    • Posada, D.1    Crandall, K.A.2
  • 77
    • 1642377363 scopus 로고    scopus 로고
    • The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4
    • Pugach, P., S. E. Kuhmann, J. Taylor, A. J. Marozsan, A. Snyder, T. Ketas, S. M. Wolinsky, B. T. Korber, and J. P. Moore. 2004. The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4. Virology 321:8-22.
    • (2004) Virology , vol.321 , pp. 8-22
    • Pugach, P.1    Kuhmann, S.E.2    Taylor, J.3    Marozsan, A.J.4    Snyder, A.5    Ketas, T.6    Wolinsky, S.M.7    Korber, B.T.8    Moore, J.P.9
  • 78
    • 0034124124 scopus 로고    scopus 로고
    • Detecting hypermutations in viral sequences with an emphasis on G→A hypermutation
    • Rose, P. P., and B. T. Korber. 2000. Detecting hypermutations in viral sequences with an emphasis on G→A hypermutation. Bioinformatics 16: 400-401.
    • (2000) Bioinformatics , vol.16 , pp. 400-401
    • Rose, P.P.1    Korber, B.T.2
  • 79
    • 0032824180 scopus 로고    scopus 로고
    • Linkage disequilibrium test implies a large effective population number for HIV in vivo
    • Rouzine, I. M., and J. M. Coffin. 1999. Linkage disequilibrium test implies a large effective population number for HIV in vivo. Proc. Natl. Acad. Sci. USA 96:10758-10763.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10758-10763
    • Rouzine, I.M.1    Coffin, J.M.2
  • 81
    • 66049139947 scopus 로고    scopus 로고
    • Salazar-Gonzalez, J. F., M. G. Salazar, B. F. Keele, G. H. Learn, E. E. Giorgi, H. Li, J. M. Decker, S. Wang, J. Baalwa, M. H. Kraus, N. F. Parrish, K. S. Shaw, M. B. Guffey, K. J. Bar, K. L. Davis, C. Ochsenbauer-Jambor, J. C. Kappes, M. S. Saag, M. S. Cohen, J. Mulenga, C. A. Derdeyn, S. Allen, E. Hunter, M. Markowitz, P. Hraber, A. S. Perelson, T. Bhattacharya, B. F. Haynes, B. T. Korber, B. H. Hahn, and G. M. Shaw. 2009. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J. Exp. Med. 206:1273-1289.
    • Salazar-Gonzalez, J. F., M. G. Salazar, B. F. Keele, G. H. Learn, E. E. Giorgi, H. Li, J. M. Decker, S. Wang, J. Baalwa, M. H. Kraus, N. F. Parrish, K. S. Shaw, M. B. Guffey, K. J. Bar, K. L. Davis, C. Ochsenbauer-Jambor, J. C. Kappes, M. S. Saag, M. S. Cohen, J. Mulenga, C. A. Derdeyn, S. Allen, E. Hunter, M. Markowitz, P. Hraber, A. S. Perelson, T. Bhattacharya, B. F. Haynes, B. T. Korber, B. H. Hahn, and G. M. Shaw. 2009. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J. Exp. Med. 206:1273-1289.
  • 82
    • 41649086532 scopus 로고    scopus 로고
    • Phylodynamics of HIV-1 in lymphoid and nonlymphoid tissues reveals a central role for the thymus in emergence of CXCR4-using quasispecies
    • Salemi, M., B. R. Burkhardt, R. R. Gray, G. Ghaffari, J. W. Sleasman, and M. M. Goodenow. 2007. Phylodynamics of HIV-1 in lymphoid and nonlymphoid tissues reveals a central role for the thymus in emergence of CXCR4-using quasispecies. PLoS One 2:e950.
    • (2007) PLoS One , vol.2
    • Salemi, M.1    Burkhardt, B.R.2    Gray, R.R.3    Ghaffari, G.4    Sleasman, J.W.5    Goodenow, M.M.6
  • 83
    • 0025133520 scopus 로고
    • Human monoclonal antibody that recognizes the V3 region of human immunodeficiency virus gp120 and neutralizes the human T-lymphotropic virus type IIIMN strain
    • Scott, C. F., Jr., S. Silver, A. T. Profy, S. D. Putney, A. Langlois, K. Weinhold, and J. E. Robinson. 1990. Human monoclonal antibody that recognizes the V3 region of human immunodeficiency virus gp120 and neutralizes the human T-lymphotropic virus type IIIMN strain. Proc. Natl. Acad. Sci. USA 87:8597-8601.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8597-8601
    • Scott Jr., C.F.1    Silver, S.2    Profy, A.T.3    Putney, S.D.4    Langlois, A.5    Weinhold, K.6    Robinson, J.E.7
  • 85
    • 34247156283 scopus 로고    scopus 로고
    • Impact of V2 mutations on escape from a potent neutralizing anti-V3 monoclonal antibody during in vitro selection of a primary human immunodeficiency virus type 1 isolate
    • Shibata, J., K. Yoshimura, A. Honda, A. Koito, T. Murakami, and S. Matsushita. 2007. Impact of V2 mutations on escape from a potent neutralizing anti-V3 monoclonal antibody during in vitro selection of a primary human immunodeficiency virus type 1 isolate. J. Virol. 81:3757-3768.
    • (2007) J. Virol , vol.81 , pp. 3757-3768
    • Shibata, J.1    Yoshimura, K.2    Honda, A.3    Koito, A.4    Murakami, T.5    Matsushita, S.6
  • 86
    • 0025253821 scopus 로고
    • Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1
    • Simmonds, P., P. Balfe, C. A. Ludlam, J. O. Bishop, and A. J. Brown. 1990. Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1. J. Virol. 64:5840-5850.
    • (1990) J. Virol , vol.64 , pp. 5840-5850
    • Simmonds, P.1    Balfe, P.2    Ludlam, C.A.3    Bishop, J.O.4    Brown, A.J.5
  • 88
    • 58149458865 scopus 로고    scopus 로고
    • Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2(-/-)gammac(-/-)) mouse model
    • ter Brake, O., N. Legrand, K. J. von Eije, M. Centlivre, H. Spits, K. Weijer, B. Blom, and B. Berkhout. 2009. Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2(-/-)gammac(-/-)) mouse model. Gene Ther. 16:148-153.
    • (2009) Gene Ther , vol.16 , pp. 148-153
    • ter Brake, O.1    Legrand, N.2    von Eije, K.J.3    Centlivre, M.4    Spits, H.5    Weijer, K.6    Blom, B.7    Berkhout, B.8
  • 89
    • 0024536114 scopus 로고
    • Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: Studies on sequential HIV isolates
    • Tersmette, M., R. A. Gruters, F. de Wolf, R. E. de Goede, J. M. Lange, P. T. Schellekens, J. Goudsmit, H. G. Huisman, and F. Miedema. 1989. Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates. J. Virol. 63:2118-2125.
    • (1989) J. Virol , vol.63 , pp. 2118-2125
    • Tersmette, M.1    Gruters, R.A.2    de Wolf, F.3    de Goede, R.E.4    Lange, J.M.5    Schellekens, P.T.6    Goudsmit, J.7    Huisman, H.G.8    Miedema, F.9
  • 90
    • 33847281316 scopus 로고    scopus 로고
    • Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion
    • Thomas, E. R., R. L. Dunfee, J. Stanton, D. Bogdan, J. Taylor, K. Kunstman, J. E. Bell, S. M. Wolinsky, and D. Gabuzda. 2007. Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion. Virology 360:105-119.
    • (2007) Virology , vol.360 , pp. 105-119
    • Thomas, E.R.1    Dunfee, R.L.2    Stanton, J.3    Bogdan, D.4    Taylor, J.5    Kunstman, K.6    Bell, J.E.7    Wolinsky, S.M.8    Gabuzda, D.9
  • 91
    • 57349127300 scopus 로고    scopus 로고
    • Tomaras, G. D., N. L. Yates, P. Liu, L. Qin, G. G. Fouda, L. L. Chavez, A. C. Decamp, R. J. Parks, V. C. Ashley, J. T. Lucas, M. Cohen, J. Eron, C. B. Hicks, H. X. Liao, S. G. Self, G. Landucci, D. N. Forthal, K. J. Weinhold, B. F. Keele, B. H. Hahn, M. L. Greenberg, L. Morris, S. S. Karim, W. A. Blattner, D. C. Montefiori, G. M. Shaw, A. S. Perelson, and B. F. Haynes. 2008. Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia. J. Virol. 82:12449-12463.
    • Tomaras, G. D., N. L. Yates, P. Liu, L. Qin, G. G. Fouda, L. L. Chavez, A. C. Decamp, R. J. Parks, V. C. Ashley, J. T. Lucas, M. Cohen, J. Eron, C. B. Hicks, H. X. Liao, S. G. Self, G. Landucci, D. N. Forthal, K. J. Weinhold, B. F. Keele, B. H. Hahn, M. L. Greenberg, L. Morris, S. S. Karim, W. A. Blattner, D. C. Montefiori, G. M. Shaw, A. S. Perelson, and B. F. Haynes. 2008. Initial B-cell responses to transmitted human immunodeficiency virus type 1: virion-binding immunoglobulin M (IgM) and IgG antibodies followed by plasma anti-gp41 antibodies with ineffective control of initial viremia. J. Virol. 82:12449-12463.
  • 95
    • 16244379228 scopus 로고    scopus 로고
    • Role of low CD4 levels in the influence of human immunodeficiency virus type 1 envelope V1 and V2 regions on entry and spread in macrophages
    • Walter, B. L., K. Wehrly, R. Swanstrom, E. Platt, D. Kabat, and B. Chesebro. 2005. Role of low CD4 levels in the influence of human immunodeficiency virus type 1 envelope V1 and V2 regions on entry and spread in macrophages. J. Virol. 79:4828-4837.
    • (2005) J. Virol , vol.79 , pp. 4828-4837
    • Walter, B.L.1    Wehrly, K.2    Swanstrom, R.3    Platt, E.4    Kabat, D.5    Chesebro, B.6
  • 96
    • 33846104485 scopus 로고    scopus 로고
    • Hematopoietic stem cell-engrafted NOD/SCID/ IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses
    • Watanabe, S., K. Terashima, S. Ohta, S. Horibata, M. Yajima, Y. Shiozawa, M. Z. Dewan, Z. Yu, M. Ito, T. Morio, N. Shimizu, M. Honda, and N. Yamamoto. 2007. Hematopoietic stem cell-engrafted NOD/SCID/ IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses. Blood 109:212-218.
    • (2007) Blood , vol.109 , pp. 212-218
    • Watanabe, S.1    Terashima, K.2    Ohta, S.3    Horibata, S.4    Yajima, M.5    Shiozawa, Y.6    Dewan, M.Z.7    Yu, Z.8    Ito, M.9    Morio, T.10    Shimizu, N.11    Honda, M.12    Yamamoto, N.13
  • 98
    • 0031041375 scopus 로고    scopus 로고
    • In vivo compartmentalization of human immunodeficiency virus: Evidence from the examination of pol sequences from autopsy tissues
    • Wong, J. K., C. C. Ignacio, F. Torriani, D. Havlir, N. J. Fitch, and D. D. Richman. 1997. In vivo compartmentalization of human immunodeficiency virus: evidence from the examination of pol sequences from autopsy tissues. J. Virol. 71:2059-2071.
    • (1997) J. Virol , vol.71 , pp. 2059-2071
    • Wong, J.K.1    Ignacio, C.C.2    Torriani, F.3    Havlir, D.4    Fitch, N.J.5    Richman, D.D.6
  • 99
    • 0028966078 scopus 로고
    • Adaptation to persistent growth in the H9 cell line renders a primary isolate of human immunodeficiency virus type 1 sensitive to neutralization by vaccine sera
    • Wrin, T., T. P. Loh, J. C. Vennari, H. Schuitemaker, and J. H. Nunberg. 1995. Adaptation to persistent growth in the H9 cell line renders a primary isolate of human immunodeficiency virus type 1 sensitive to neutralization by vaccine sera. J. Virol. 69:39-48.
    • (1995) J. Virol , vol.69 , pp. 39-48
    • Wrin, T.1    Loh, T.P.2    Vennari, J.C.3    Schuitemaker, H.4    Nunberg, J.H.5
  • 100
    • 53249113124 scopus 로고    scopus 로고
    • Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference viruses
    • Wu, X. L., A. Sambor, M. C. Nason, Z. Y. Yang, L. Wu, S. Zolla-Pazner, G. J. Nabel, and J. R. Mascola. 2008. Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference viruses. Virology 380:285-295.
    • (2008) Virology , vol.380 , pp. 285-295
    • Wu, X.L.1    Sambor, A.2    Nason, M.C.3    Yang, Z.Y.4    Wu, L.5    Zolla-Pazner, S.6    Nabel, G.J.7    Mascola, J.R.8
  • 101
    • 0038004471 scopus 로고    scopus 로고
    • The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
    • Zhang, H., B. Yang, R. J. Pomerantz, C. Zhang, S. C. Arunachalam, and L. Gao. 2003. The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. Nature 424:94-98.
    • (2003) Nature , vol.424 , pp. 94-98
    • Zhang, H.1    Yang, B.2    Pomerantz, R.J.3    Zhang, C.4    Arunachalam, S.C.5    Gao, L.6
  • 102
    • 33947596455 scopus 로고    scopus 로고
    • HIV-1 infection and pathogenesis in a novel humanized mouse model
    • Zhang, L., G. I. Kovalev, and L. Su. 2007. HIV-1 infection and pathogenesis in a novel humanized mouse model. Blood 109:2978-2981.
    • (2007) Blood , vol.109 , pp. 2978-2981
    • Zhang, L.1    Kovalev, G.I.2    Su, L.3
  • 103
    • 9744280420 scopus 로고    scopus 로고
    • Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin
    • Zhang, M., B. Gaschen, W. Blay, B. Foley, N. Haigwood, C. Kuiken, and B. Korber. 2004. Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin. Glycobiology 14:1229-1246.
    • (2004) Glycobiology , vol.14 , pp. 1229-1246
    • Zhang, M.1    Gaschen, B.2    Blay, W.3    Foley, B.4    Haigwood, N.5    Kuiken, C.6    Korber, B.7


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