The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats

Brain Research

Volumn 1321, Issue , 2010, Pages 40-50

  Sirianni, Rachael W ^a   Olausson, Peter ^b   Chiu, Amy S ^a   Taylor, Jane R ^b   Saltzman, W Mark ^a  

^a Yale University   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BDNF; Depression; Hippocampus; Neuroplasticity; Neurotrophin; Polymeric drug delivery

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG MECHANISM; DRUG RELEASE; DRUG TOLERANCE; HIPPOCAMPUS; MALE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ALGINATES; ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; BIOCOMPATIBLE MATERIALS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DEPRESSION; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUCURONIC ACID; HEXURONIC ACIDS; HIPPOCAMPUS; MALE; MICROSPHERES; NEURONAL PLASTICITY; POLYVINYLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKA; STRESS, PSYCHOLOGICAL;

RATTUS;

EID: 77549088701     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.01.041     Document Type: Article

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