Simultaneous GDNF and BDNF application leads to increased motoneuron survival and improved functional outcome in an experimental model for obstetric brachial plexus lesions

Plastic and Reconstructive Surgery

Volumn 110, Issue 4, 2002, Pages 1066-1072

  Aszmann, Oskar C ^a   Korak, Klaus J ^a   Kropf, Nina ^a   Fine, Eric ^a   Aebischer, Patrick ^a   Frey, Manfred ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRACHIAL PLEXUS INJURY; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; FEMALE; FUNCTIONAL ASSESSMENT; MOTONEURON; NONHUMAN; PRIORITY JOURNAL; RAT; SLOW RELEASE FORMULATION; TREATMENT OUTCOME;

EID: 0037105846     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006534-200209150-00010     Document Type: Article

References (35)

1. Brachial plexus birth palsy: A 10 year report on the incidence and prognosis
2. Brachialplexus palsy in the newborn
3. Birth and fertility rates for states: United States, 1990
4. Indications and results of brachial plexus surgery in obstetrical palsy
5. The complete histo-pathological examination of the nervous system of an unusual case of obstetrical paralysis forty-one years after birth, and a review of the pathology
6. Ueber die veraenderungen der ganglienzellen am fazialiskern des kaninchens nach ausreissung der nerven
7. Motoneuron death after sciatic nerve section in newborn rats
8. The effects of wing bud extirpation on the development of the central nervous system in chick embryos
9. GDNF: A potent survival factor for motorneurons present in peripheral nerve and muscle
10. Glial cell line-derived neurotrophic factor (GDNF): A new neurotrophic factor for motoneurones
11. In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
12. Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF
13. Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo
14. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
15. Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death
16. BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth
17. Synergistic but transient rescue effects of BDNF and GDNF on axotomized neonatal motoneurons
18. Principles of horseradish peroxidase neurohistochemistry and their applications for tracing neural pathways: Axonal transport, enzyme histo-chemistry and light microscopic analysis
19. Estimation of nuclear population from microtome sections
20. Ventral root avulsion: An experimental model of death of adult motor neurons
21. Nerve crush injuries: A model for axonotmesis
22. Electron-microscopic observations on the effects of localized crush injuries on the connective tissue on peripheral nerve
23. Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve
24. Changes of nerve growth factor synthesis in non-neuronal cells in response to sciatic nerve transection
25. Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: Different mechanisms are responsible for the regulation of BDNF and NGF mRNA
26. Restoration of blood-nerve barrier in neuropathy is associated with axonal regeneration and remyelination
27. Blood-nerve barrier: Ultrastructural and endothelial surface charge alterations following nerve crush
28. A reassessment of the accuracy of reinnervation by motoneurons following crushing or freezing of the sciatic or lumbar spinal nerves of rats
29. Expression of neurotrophins in skeletal muscle: Quantitative comparison and significance for motoneuron survival and maintenance of function
30. The neurotrophins BDNF, NT-3 and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons
31. Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo
32. Innervation ratio is an important determinant of force in normal and reinnervated rat tibialis anterior muscle
33. Electromyographic and morphological functional compensation in late poliomyelitis