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Volumn 727, Issue 1-2, 1996, Pages 169-181

Transport and elimination of recombinant human NGF during long-term delivery to the brain

Author keywords

Brain interstitium; Controlled release; Diffusion; Elimination; Polymer; Recombinant human nerve growth factor

Indexed keywords

POLYMER; RECOMBINANT NERVE GROWTH FACTOR;

EID: 0030586332     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00378-2     Document Type: Article
Times cited : (88)

References (73)
  • 1
    • 0019781601 scopus 로고
    • A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer's disease
    • [1] Appel, S.H., A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer's disease, Ann. Neurol., 10 (1981) 499-505.
    • (1981) Ann. Neurol. , vol.10 , pp. 499-505
    • Appel, S.H.1
  • 2
    • 0025130888 scopus 로고
    • Human β nerve growth factor obtained from a baculovirus expression system has potent in vitro and in vivo neurotrophic activity
    • [2] Barnett, J., Baecker, P., Routledge-Ward, C. et al., Human β nerve growth factor obtained from a baculovirus expression system has potent in vitro and in vivo neurotrophic activity, Exp. Neurol., 110 (1990) 11-24.
    • (1990) Exp. Neurol. , vol.110 , pp. 11-24
    • Barnett, J.1    Baecker, P.2    Routledge-Ward, C.3
  • 3
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • [3] Bartus, R.T., Dean, R.L., Beer, B. et al., The cholinergic hypothesis of geriatric memory dysfunction, Science, 217 (1982) 408-417.
    • (1982) Science , vol.217 , pp. 408-417
    • Bartus, R.T.1    Dean, R.L.2    Beer, B.3
  • 4
    • 0027258361 scopus 로고
    • Controlled growth factor delivery induces differential neurite outgrowth in three-dimensional cell cultures
    • [4] Beaty, C.E. and Saltzman, W.M., Controlled growth factor delivery induces differential neurite outgrowth in three-dimensional cell cultures. J. Control. Release, 24 (1993) 15-23.
    • (1993) J. Control. Release , vol.24 , pp. 15-23
    • Beaty, C.E.1    Saltzman, W.M.2
  • 5
    • 0027536084 scopus 로고
    • Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery
    • [5] Bickel, U., Yoshikawa, T., Landaw, E.M. et al., Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery, Proc. Natl. Acad. Sci. USA, 90 (1993) 2618-2622.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2618-2622
    • Bickel, U.1    Yoshikawa, T.2    Landaw, E.M.3
  • 6
    • 0024317164 scopus 로고
    • Production and characterization of biologically active recombinant human nerve growth factor
    • [6] Bruce, G. and Heinrich, G., Production and characterization of biologically active recombinant human nerve growth factor, Neurobiol. Aging, 10 (1989) 89-94.
    • (1989) Neurobiol. Aging , vol.10 , pp. 89-94
    • Bruce, G.1    Heinrich, G.2
  • 7
    • 0026713078 scopus 로고
    • Activity and biospecificity of proteolyzed forms and dimeric combinations of recombinant human and murine nerve growth factor
    • [7] Burton, L.E., Schmelzer, C.H., Szonyi, E. et al., Activity and biospecificity of proteolyzed forms and dimeric combinations of recombinant human and murine nerve growth factor, J. Neurochem., 59 (1992) 1937-1945.
    • (1992) J. Neurochem. , vol.59 , pp. 1937-1945
    • Burton, L.E.1    Schmelzer, C.H.2    Szonyi, E.3
  • 8
    • 0026064275 scopus 로고
    • Single-step purification and biological activity of human nerve growth factor produced from insect cells
    • [8] Buxser, S., Vroegop, S., Decker, D. et al., Single-step purification and biological activity of human nerve growth factor produced from insect cells, J. Neurochem., 56 (1991) 347-351.
    • (1991) J. Neurochem. , vol.56 , pp. 347-351
    • Buxser, S.1    Vroegop, S.2    Decker, D.3
  • 9
    • 0026628154 scopus 로고
    • Sustained release of nerve growth factor from biodegradable polymer microspheres
    • [9] Camarata, P.J., Suryanarayanan, R. and Turner, D.A., Sustained release of nerve growth factor from biodegradable polymer microspheres, Neurosurgery, 30 (1992) 313-319.
    • (1992) Neurosurgery , vol.30 , pp. 313-319
    • Camarata, P.J.1    Suryanarayanan, R.2    Turner, D.A.3
  • 10
    • 0019504427 scopus 로고
    • The isolation and characterization of nerve growth factor from the prostate gland of the guinea-pig
    • [10] Chapman, C.A., Banks, B.E.C, Vernon, C.A. et al., The isolation and characterization of nerve growth factor from the prostate gland of the guinea-pig, Eur. J. Biochem., 115 (1981) 347-351.
    • (1981) Eur. J. Biochem. , vol.115 , pp. 347-351
    • Chapman, C.A.1    Banks, B.E.C.2    Vernon, C.A.3
  • 11
    • 0028965223 scopus 로고
    • Somatic gene transfer of NGF to the aged brain: Behavioral and morphological amelioration
    • [11] Chen, K.S. and Gage, F.H., Somatic gene transfer of NGF to the aged brain: Behavioral and morphological amelioration, J. Neurosci., 15 (1995) 2819-2825.
    • (1995) J. Neurosci. , vol.15 , pp. 2819-2825
    • Chen, K.S.1    Gage, F.H.2
  • 12
    • 0028171962 scopus 로고
    • 125l]nerve growth factor by cholinergic neurons and down-regulated trkA expression in the medal septum of aged rats
    • 125l]nerve growth factor by cholinergic neurons and down-regulated trkA expression in the medal septum of aged rats, Neuroscience, 62 (1994) 625-629.
    • (1994) Neuroscience , vol.62 , pp. 625-629
    • Cooper, J.D.1    Lindholm, D.2    Sofroniew, M.V.3
  • 13
    • 0020686674 scopus 로고
    • Alzheimer's disease: A disorder of cortical cholinergic innervation
    • [13] Coyle, J.T., Price, D.L. and DeLong, M.R., Alzheimer's disease: A disorder of cortical cholinergic innervation, Science, 219 (1983) 1184-1190.
    • (1983) Science , vol.219 , pp. 1184-1190
    • Coyle, J.T.1    Price, D.L.2    DeLong, M.R.3
  • 14
    • 0027197191 scopus 로고
    • Detection of NGF-like activity in human brain tissue: Increased levels in Alzheimer's disease
    • [14] Crutcher, K.A., Scott, S.A., Liang, S. et al., Detection of NGF-like activity in human brain tissue: Increased levels in Alzheimer's disease, J. Neurosci., 13 (1993) 2540-2550.
    • (1993) J. Neurosci. , vol.13 , pp. 2540-2550
    • Crutcher, K.A.1    Scott, S.A.2    Liang, S.3
  • 15
    • 0014904609 scopus 로고
    • Cerebrospinal fluid production rates determined by simultaneous albumin and inulin perfusion
    • [15] Curran, R.E., Mosher, M.B., Owens, E.S. et al., Cerebrospinal fluid production rates determined by simultaneous albumin and inulin perfusion. Exp. Neurol., 29 (1970) 546-553.
    • (1970) Exp. Neurol. , vol.29 , pp. 546-553
    • Curran, R.E.1    Mosher, M.B.2    Owens, E.S.3
  • 16
    • 0021984647 scopus 로고
    • Is it possible to design rational treatment for the symptoms of Alzheimer's disease?
    • [16] Davies, P., Is it possible to design rational treatment for the symptoms of Alzheimer's disease?, Drug Dev. Res., 5 (1985) 69-75.
    • (1985) Drug Dev. Res. , vol.5 , pp. 69-75
    • Davies, P.1
  • 17
    • 0026756286 scopus 로고
    • A double-blind, placebocontrolled multicenter study of tacrine for Alzheimer's disease
    • [17] Davis, K.L., Thal, L.J., Elkan, R.G. et al., A double-blind, placebocontrolled multicenter study of tacrine for Alzheimer's disease, N. Engl. J. Med., 327 (1992) 1253-1259.
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1253-1259
    • Davis, K.L.1    Thal, L.J.2    Elkan, R.G.3
  • 18
    • 0028130227 scopus 로고
    • Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: Rescue and sprouting of degenerating cholinergic basal forebrain neurons
    • [18] Emerich, D.F., Winn, S.R., Harper, J. et al., Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons, J. Comp. Neurol., 349 (1994) 148-164.
    • (1994) J. Comp. Neurol. , vol.349 , pp. 148-164
    • Emerich, D.F.1    Winn, S.R.2    Harper, J.3
  • 19
    • 0026038715 scopus 로고
    • Receptor-mediated retrograde transport in CNS neurons after intraventricular administration of NGF and growth factors
    • [19] Ferguson, I.A., Schweitzer, J.B., Bartlett, P.F. et al., Receptor-mediated retrograde transport in CNS neurons after intraventricular administration of NGF and growth factors, J. Comp. Neurol., 313 (1991) 680-692.
    • (1991) J. Comp. Neurol. , vol.313 , pp. 680-692
    • Ferguson, I.A.1    Schweitzer, J.B.2    Bartlett, P.F.3
  • 20
    • 0023643241 scopus 로고
    • Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor
    • [20] Fischer, W., Wictorin, K., Bjorklund, A. et al., Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor, Nature, 329 (1987) 65-68.
    • (1987) Nature , vol.329 , pp. 65-68
    • Fischer, W.1    Wictorin, K.2    Bjorklund, A.3
  • 21
    • 0027398553 scopus 로고
    • Blood-brain barrier penetration and in vivo activity of an NGF conjugate
    • [21] Friden, P.M., Walus, L.R., Watson, P. et al., Blood-brain barrier penetration and in vivo activity of an NGF conjugate, Science, 259 (1993) 373-377.
    • (1993) Science , vol.259 , pp. 373-377
    • Friden, P.M.1    Walus, L.R.2    Watson, P.3
  • 22
    • 0023835556 scopus 로고
    • Morphological response of axotomized septal neurons to nerve growth factor
    • [22] Gage, F., Armstrong, D., Williams, L. et al., Morphological response of axotomized septal neurons to nerve growth factor, J. Comp. Neurol., 269 (1988) 147-155.
    • (1988) J. Comp. Neurol. , vol.269 , pp. 147-155
    • Gage, F.1    Armstrong, D.2    Williams, L.3
  • 23
    • 0012082759 scopus 로고
    • Dependence of traumatic brain edema on immunologic reactivity against tissue antigens
    • H.M. Pappius and W. Feindel Eds., Springer-Verlag, New York
    • [23] Gannushkina, I.V., Sukhorukova, L.I. and Baranchikova, M.V., Dependence of traumatic brain edema on immunologic reactivity against tissue antigens. In H.M. Pappius and W. Feindel (Eds.), Dynamics of Brain Edema, Springer-Verlag, New York, 1976, pp. 155-160.
    • (1976) Dynamics of Brain Edema , pp. 155-160
    • Gannushkina, I.V.1    Sukhorukova, L.I.2    Baranchikova, M.V.3
  • 24
    • 0018238503 scopus 로고
    • Isolation of human nerve growth factor from placental tissue
    • [24] Goldstein, L.D., Reynolds, C.P. and Perez-Polo, J.R., Isolation of human nerve growth factor from placental tissue, Neurochem. Res., 3 (1978) 175-183.
    • (1978) Neurochem. Res. , vol.3 , pp. 175-183
    • Goldstein, L.D.1    Reynolds, C.P.2    Perez-Polo, J.R.3
  • 25
    • 0017194558 scopus 로고
    • The carrier potential of liposomes in biology and medicine
    • [25] Gregoriadis, G., The carrier potential of liposomes in biology and medicine, N. Engl. J. Med., 295 (1976) 704-710.
    • (1976) N. Engl. J. Med. , vol.295 , pp. 704-710
    • Gregoriadis, G.1
  • 26
    • 0020490872 scopus 로고
    • The purification of nerve growth factor from bovine seminal plasma
    • [26] Harper, G.P., Glanville, R.W. and Thoenen, H., The purification of nerve growth factor from bovine seminal plasma, J. Biol. Chem., 257 (1982) 8541-8548.
    • (1982) J. Biol. Chem. , vol.257 , pp. 8541-8548
    • Harper, G.P.1    Glanville, R.W.2    Thoenen, H.3
  • 27
    • 0018861591 scopus 로고
    • The distribution of nerve growth factor in the male sex organs of mammals
    • [27] Harper, G.P. and Thoenen, H., The distribution of nerve growth factor in the male sex organs of mammals. J. Neurochem., 34 (1980) 893-903.
    • (1980) J. Neurochem. , vol.34 , pp. 893-903
    • Harper, G.P.1    Thoenen, H.2
  • 28
    • 0024213874 scopus 로고
    • Comparison of nerve growth factor's effects on development of septum, striatum, and nucleus basalis cholinergic neurons in vitro
    • [28] Hartikka, J. and Hefti, F., Comparison of nerve growth factor's effects on development of septum, striatum, and nucleus basalis cholinergic neurons in vitro. J. Neurosci. Res., 21 (1988) 352-364.
    • (1988) J. Neurosci. Res. , vol.21 , pp. 352-364
    • Hartikka, J.1    Hefti, F.2
  • 29
    • 0021359024 scopus 로고
    • Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions
    • [29] Hefti, F., Dravid, A. and Hartikka, J., Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions, Brain Res., 293 (1984) 305-311.
    • (1984) Brain Res. , vol.293 , pp. 305-311
    • Hefti, F.1    Dravid, A.2    Hartikka, J.3
  • 30
    • 0021955153 scopus 로고
    • Nerve growth factor increases choline acetyltransferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neurons
    • [30] Hefti, F., Hartikka, J., Eckenstein, F. et al., Nerve growth factor increases choline acetyltransferase but not survival or fiber outgrowth of cultured fetal septal cholinergic neurons, Neuroscience. 14 (1985) 55-68.
    • (1985) Neuroscience , vol.14 , pp. 55-68
    • Hefti, F.1    Hartikka, J.2    Eckenstein, F.3
  • 31
    • 0024394332 scopus 로고
    • Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases
    • [31] Hefti, F., Hartikka, J. and Knusel, B., Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases, Neurobiol. Aging, 10 (1989) 515-533.
    • (1989) Neurobiol. Aging , vol.10 , pp. 515-533
    • Hefti, F.1    Hartikka, J.2    Knusel, B.3
  • 32
    • 0024351750 scopus 로고
    • Localization of nerve growth factor receptors in the normal human brain and in Alzheimer's disease
    • [32] Hefti, F. and Mash, D., Localization of nerve growth factor receptors in the normal human brain and in Alzheimer's Disease, Neurobiol. Aging, 10 (1989) 75-87.
    • (1989) Neurobiol. Aging , vol.10 , pp. 75-87
    • Hefti, F.1    Mash, D.2
  • 33
    • 0022549757 scopus 로고
    • Nerve growth factor and Alzheimer's disease
    • [33] Hefti, F. and Weiner, W.J., Nerve growth factor and Alzheimer's disease. Ann. Neurol., 20 (1986) 275-281.
    • (1986) Ann. Neurol. , vol.20 , pp. 275-281
    • Hefti, F.1    Weiner, W.J.2
  • 34
    • 0014314845 scopus 로고
    • Brain and choroid plexus blood volumes in vertebrates
    • [34] Heisey, S.R., Brain and choroid plexus blood volumes in vertebrates, Comp. Biochem. Physiol., 26 (1968) 489-498.
    • (1968) Comp. Biochem. Physiol. , vol.26 , pp. 489-498
    • Heisey, S.R.1
  • 35
    • 0024709111 scopus 로고
    • NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat
    • [35] Higgins, G.A., Koh, S., Chen, K.S. et al., NGF induction of NGF receptor gene expression and cholinergic neuronal hypertrophy within the basal forebrain of the adult rat, Neuron, 3 (1989) 247-256.
    • (1989) Neuron , vol.3 , pp. 247-256
    • Higgins, G.A.1    Koh, S.2    Chen, K.S.3
  • 36
    • 0025115891 scopus 로고
    • NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria-fornix lesion
    • [36] Hoffman, D., Wahlberg, L. and Aebischer, P., NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria-fornix lesion, Exp. Neurol., 110 (1990) 39-44.
    • (1990) Exp. Neurol. , vol.110 , pp. 39-44
    • Hoffman, D.1    Wahlberg, L.2    Aebischer, P.3
  • 37
    • 0000446098 scopus 로고
    • Nerve growth factor in snake venoms
    • C.-Y. Lee Eds., Springer-Verlag, Berlin
    • [37] Hogue-Angeletti, R.A. and Bradshaw, R.A., Nerve growth factor in snake venoms. In C.-Y. Lee (Eds.), Handbook of Experimental Pharmacology, Springer-Verlag, Berlin, 1979, pp. 276-294.
    • (1979) Handbook of Experimental Pharmacology , pp. 276-294
    • Hogue-Angeletti, R.A.1    Bradshaw, R.A.2
  • 38
    • 0025006745 scopus 로고
    • Production, purification and characterization of biologically active recommbinant human nerve growth factor
    • [38] Iwane, M., Kitamura, Y., Kaisho, Y. et al., Production, purification and characterization of biologically active recommbinant human nerve growth factor, Biochem. Biophys. Res. Commun., 171 (1990) 116-122.
    • (1990) Biochem. Biophys. Res. Commun. , vol.171 , pp. 116-122
    • Iwane, M.1    Kitamura, Y.2    Kaisho, Y.3
  • 39
    • 0028129444 scopus 로고
    • NGF mRNA is not decreased in frontal cortex from Alzheimer's disease patients
    • [39] Jetté, N., Cole, M.S. and Fahnestock, M., NGF mRNA is not decreased in frontal cortex from Alzheimer's disease patients, Mol. Brain Res., 25 (1994) 242-250.
    • (1994) Mol. Brain Res. , vol.25 , pp. 242-250
    • Jetté, N.1    Cole, M.S.2    Fahnestock, M.3
  • 40
    • 0021930240 scopus 로고
    • Development of cholinergic drugs for the treatment of Alzheimer's disease
    • [40] Johns, C.A., Haroutunian, V., Greenwald, B.S. et al., Development of cholinergic drugs for the treatment of Alzheimer's disease, Drug Dev. Res., 5 (1985) 77-96.
    • (1985) Drug Dev. Res. , vol.5 , pp. 77-96
    • Johns, C.A.1    Haroutunian, V.2    Greenwald, B.S.3
  • 41
    • 0024454594 scopus 로고
    • Synthesis and secretion of nerve growth factor by Saccharomyces cerevisiae
    • [41] Kanaya, E., Higashizaki, T., Ozawa, F. et al., Synthesis and secretion of nerve growth factor by Saccharomyces cerevisiae, Gene, 83 (1989) 65-74.
    • (1989) Gene , vol.83 , pp. 65-74
    • Kanaya, E.1    Higashizaki, T.2    Ozawa, F.3
  • 42
    • 0025634155 scopus 로고
    • Trophic actions of recombinant human nerve growth factor on cultured rat embryonic CNS cells
    • [42] Knusel, B., Burton, L., Longo, F. et al., Trophic actions of recombinant human nerve growth factor on cultured rat embryonic CNS cells, Exp. Neurol., 110 (1990) 274-283.
    • (1990) Exp. Neurol. , vol.110 , pp. 274-283
    • Knusel, B.1    Burton, L.2    Longo, F.3
  • 43
    • 0025780387 scopus 로고
    • Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat
    • [43] Koliatsos, V., Applegate, M., Knusel, B. et al., Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat, Exp. Neurol., 112 (1991) 161-173.
    • (1991) Exp. Neurol. , vol.112 , pp. 161-173
    • Koliatsos, V.1    Applegate, M.2    Knusel, B.3
  • 44
    • 0025718569 scopus 로고
    • Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates
    • [44] Koliatsos, V.E., Clatterbuck, B.S., Nauta, G.J.W. et al., Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates, Ann. Neurol., 30 (1991) 831-840.
    • (1991) Ann. Neurol. , vol.30 , pp. 831-840
    • Koliatsos, V.E.1    Clatterbuck, B.S.2    Nauta, G.J.W.3
  • 45
    • 0028020905 scopus 로고
    • The aged monkey basal forebrain: Rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor
    • [45] Kordower, J.H., Winn, S.R., Liu, Y.-T. et al., The aged monkey basal forebrain: Rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor, Proc. Natl. Acad. Sci. USA, 91 (1994) 10898-10902.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10898-10902
    • Kordower, J.H.1    Winn, S.R.2    Liu, Y.-T.3
  • 46
    • 0029045339 scopus 로고
    • Distribution of nerve growth factor following direct delivery to brain interstitium
    • [46] Krewson, C.E., Klarman, M.L. and Saltzman, W.M., Distribution of nerve growth factor following direct delivery to brain interstitium, Brain Res., 680 (1995) 196-206.
    • (1995) Brain Res. , vol.680 , pp. 196-206
    • Krewson, C.E.1    Klarman, M.L.2    Saltzman, W.M.3
  • 47
    • 0012054610 scopus 로고
    • Targetting of peptides and proteins in the brain following release from implantable polymers
    • V.H.L. Lee, M. Hasida and Y. Mizushima Eds., Harwood Academic Publishers, London
    • [47] Krewson, C.E. and Saltzman, W.M., Targetting of peptides and proteins in the brain following release from implantable polymers. In V.H.L. Lee, M. Hasida and Y. Mizushima (Eds.), Trends and Future Perspectives in Peptide and Protein Drug Delivery, Harwood Academic Publishers, London, 1995, pp. 273-294.
    • (1995) Trends and Future Perspectives in Peptide and Protein Drug Delivery , pp. 273-294
    • Krewson, C.E.1    Saltzman, W.M.2
  • 48
    • 0027335526 scopus 로고
    • 125l]nerve growth factor in the rat brain following a single intraventricular injection: Correlation with the topographical distribution of trkA messenger RNA-expressing cells
    • 125l]nerve growth factor in the rat brain following a single intraventricular injection: Correlation with the topographical distribution of trkA messenger RNA-expressing cells, Neuroscience, 54 (1993) 445-460.
    • (1993) Neuroscience , vol.54 , pp. 445-460
    • Lapchak, P.A.1    Araujo, D.M.2    Carswell, S.3
  • 49
    • 0029001712 scopus 로고
    • Convection-enhanced distribution of large molecules in gray matter during interstitial infusion
    • [49] Lieberman, D.M., Laske, D.W., Morrison, P.F. et al., Convection-enhanced distribution of large molecules in gray matter during interstitial infusion, J. Neurosurg., 82 (1995) 1021-1029.
    • (1995) J. Neurosurg. , vol.82 , pp. 1021-1029
    • Lieberman, D.M.1    Laske, D.W.2    Morrison, P.F.3
  • 50
    • 0023814370 scopus 로고
    • Rescue of lesioned septal cholinergic neurons by nerve growth factor: Specificity and requirement for chronic treatment
    • [50] Montero, C.N. and Hefti, F., Rescue of lesioned septal cholinergic neurons by nerve growth factor: Specificity and requirement for chronic treatment, J. Neurosci., 8 (1988) 2986-2999.
    • (1988) J. Neurosci. , vol.8 , pp. 2986-2999
    • Montero, C.N.1    Hefti, F.2
  • 51
    • 0027380155 scopus 로고
    • Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection
    • [51] Morse, J.K., Wiegand, S.J., Anderson, K. et al., Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection, J. Neurosci., 13 (1993) 4146-4156.
    • (1993) J. Neurosci. , vol.13 , pp. 4146-4156
    • Morse, J.K.1    Wiegand, S.J.2    Anderson, K.3
  • 52
    • 0029039162 scopus 로고
    • Nerve growth factor in Alzheimer's disease: Defective retrograde transport to nucleus basalis
    • [52] Mufson, E.J., Conner, J.M. and Kordower, J.H., Nerve growth factor in Alzheimer's disease: defective retrograde transport to nucleus basalis, Neuroreport, 6 (1995) 1063-1066.
    • (1995) Neuroreport , vol.6 , pp. 1063-1066
    • Mufson, E.J.1    Conner, J.M.2    Kordower, J.H.3
  • 53
    • 0027276502 scopus 로고
    • NGF level is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with Alzheimer's disease
    • [53] Murase, K., Nabeshima, T., Robitaille, Y. et al., NGF level is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with Alzheimer's disease, Biochem. Biophys. Res. Comm., 193 (1993) 198-203.
    • (1993) Biochem. Biophys. Res. Comm. , vol.193 , pp. 198-203
    • Murase, K.1    Nabeshima, T.2    Robitaille, Y.3
  • 55
    • 0016714197 scopus 로고
    • Measurements of dog blood-brain transfer constants by ventriculocisternal perfusion
    • [55] Patlak, C. and Fenstermacher, J., Measurements of dog blood-brain transfer constants by ventriculocisternal perfusion, Am. J. Physiol., 229 (1975) 877-884.
    • (1975) Am. J. Physiol. , vol.229 , pp. 877-884
    • Patlak, C.1    Fenstermacher, J.2
  • 56
    • 0024379073 scopus 로고
    • Potential use of nerve growth factor to treat Alzheimer's disease
    • [56] Phelps, C., Gage, F., Growdon, J. et al., Potential use of nerve growth factor to treat Alzheimer's disease, Neurobiol. Aging, 10 (1989) 205-207.
    • (1989) Neurobiol. Aging , vol.10 , pp. 205-207
    • Phelps, C.1    Gage, F.2    Growdon, J.3
  • 57
    • 0028301348 scopus 로고
    • Macromolecular permeability across the blood-nerve and blood-brain barriers
    • [57] Poduslo, J.F., Curran, G.L. and Berg. C.T., Macromolecular permeability across the blood-nerve and blood-brain barriers, Proc. Natl. Acad. Sci. USA, 91 (1994) 5705-5709.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5705-5709
    • Poduslo, J.F.1    Curran, G.L.2    Berg, C.T.3
  • 58
    • 0025287008 scopus 로고
    • Controlled release of nerve growth factor from a polymeric implant
    • [58] Powell, E.M., Sobarzo, M.R. and Saltzman, W.M., Controlled release of nerve growth factor from a polymeric implant, Brain Res., 515 (1990) 309-311.
    • (1990) Brain Res. , vol.515 , pp. 309-311
    • Powell, E.M.1    Sobarzo, M.R.2    Saltzman, W.M.3
  • 59
    • 0012051460 scopus 로고
    • The role of tissue penetration and bulk flow in the formation and resolution of cold-induced edema
    • H.M. Pappius and W. Feindel Eds., Springer-Verlag, New York
    • [59] Reulen, H.J., Graham, R., Fenske, M. et al., The role of tissue penetration and bulk flow in the formation and resolution of cold-induced edema. In H.M. Pappius and W. Feindel (Eds.), Dynamics of Brain Edema, Springer-Verlag, New York, 1976, pp. 103-112.
    • (1976) Dynamics of Brain Edema , pp. 103-112
    • Reulen, H.J.1    Graham, R.2    Fenske, M.3
  • 60
    • 0017351916 scopus 로고
    • Role of pressure gradients and bulk flow in dynamics of vasogenic brain edema
    • [60] Reulen, H.J., Graham, R., Spatz, M. et al., Role of pressure gradients and bulk flow in dynamics of vasogenic brain edema, J. Neurosurg., 46 (1977) 24-35.
    • (1977) J. Neurosurg. , vol.46 , pp. 24-35
    • Reulen, H.J.1    Graham, R.2    Spatz, M.3
  • 61
    • 0017884986 scopus 로고
    • Clearance of edema fluid into cerebrospinal fluid
    • [61] Reulen, H.J., Tsuyumu, M., Tack, A. et al., Clearance of edema fluid into cerebrospinal fluid, J. Neurosurg., 48 (1978) 754-764.
    • (1978) J. Neurosurg. , vol.48 , pp. 754-764
    • Reulen, H.J.1    Tsuyumu, M.2    Tack, A.3
  • 62
    • 0018903891 scopus 로고
    • Bulk flow of brain interstitial fluid under normal and hyperosmolar conditions
    • [62] Rosenberg, G., Kyner, W. and Estrada, E., Bulk flow of brain interstitial fluid under normal and hyperosmolar conditions, Am. J. Physiol., 238 (1980) F42-F49.
    • (1980) Am. J. Physiol. , vol.238
    • Rosenberg, G.1    Kyner, W.2    Estrada, E.3
  • 63
    • 0012051294 scopus 로고
    • Controlled intracranial delivery of antibodies in the rat
    • J. Cleland and R. Langer Eds., American Chemical Society, Washington, DC
    • [63] Salehi-Had, S. and Saltzman, W.M., Controlled intracranial delivery of antibodies in the rat. In J. Cleland and R. Langer (Eds.), Formulation and Delivery of Proteins and Peptides, American Chemical Society, Washington, DC, 1994, pp. 278-291.
    • (1994) Formulation and Delivery of Proteins and Peptides , pp. 278-291
    • Salehi-Had, S.1    Saltzman, W.M.2
  • 64
    • 0025771713 scopus 로고
    • Drugs released from polymers: Diffusion and elimination in brain tissue
    • [64] Saltzman, W.M. and Radomsky, M.L., Drugs released from polymers: Diffusion and elimination in brain tissue, Chem. Engin. Sci., 46 (1991) 2429-2444.
    • (1991) Chem. Engin. Sci. , vol.46 , pp. 2429-2444
    • Saltzman, W.M.1    Radomsky, M.L.2
  • 65
    • 0026648751 scopus 로고
    • Biochemical characterization of recombinant human nerve growth factor
    • [65] Schmelzer, C.H., Burton, L.E., Chan, W.-P. et al., Biochemical characterization of recombinant human nerve growth factor, J. Neurochem., 59 (1992) 1675-1683.
    • (1992) J. Neurochem. , vol.59 , pp. 1675-1683
    • Schmelzer, C.H.1    Burton, L.E.2    Chan, W.-P.3
  • 66
    • 0027731159 scopus 로고
    • Intracranial infusion of purified nerve growth factor to an Alzheimer patient: The first attempt of a possible future treatment strategy
    • [66] Seiker, Å., Nordberg, A., von Holst, H. et al., Intracranial infusion of purified nerve growth factor to an Alzheimer patient: the first attempt of a possible future treatment strategy, Behav. Brain Res., 57 (1993) 255-261.
    • (1993) Behav. Brain Res. , vol.57 , pp. 255-261
    • Seiker, A.1    Nordberg, A.2    Von Holst, H.3
  • 67
    • 0022001038 scopus 로고
    • Direct evidence for brain-specific release of dopamine from a redox delivery system
    • [67] Simpkins, J., Bodor, N. and Enz, A., Direct evidence for brain-specific release of dopamine from a redox delivery system, J. Pharmaceut. Sci., 74 (1985) 1033-1036.
    • (1985) J. Pharmaceut. Sci. , vol.74 , pp. 1033-1036
    • Simpkins, J.1    Bodor, N.2    Enz, A.3
  • 69
    • 0029013323 scopus 로고
    • Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery
    • [69] Tuszynski, M.H. and Gage, F.H., Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery, Proc. Natl. Acad. Sci. USA, 92 (1995) 4621-4625.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4621-4625
    • Tuszynski, M.H.1    Gage, F.H.2
  • 70
    • 0020617520 scopus 로고
    • Human β-nerve growth factor gene sequence highly homologous to that of mouse
    • [70] Ullrich, A., Gray, A., Berman, C. et al., Human β-nerve growth factor gene sequence highly homologous to that of mouse, Nature, 303 (1983) 821-825.
    • (1983) Nature , vol.303 , pp. 821-825
    • Ullrich, A.1    Gray, A.2    Berman, C.3
  • 71
    • 0001641539 scopus 로고
    • Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection
    • [71] Williams, L., Varon, S., Peterson, G. et al., Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection, Proc Natl Acad Sci USA, 83 (1986) 9231-9235.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 9231-9235
    • Williams, L.1    Varon, S.2    Peterson, G.3
  • 72
    • 0028343937 scopus 로고
    • Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the suvival of axotomized septal cholinergic neurons
    • [72] Winn, S.R., Hammang, J.P., Emerich, D.F. et al., Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the suvival of axotomized septal cholinergic neurons, Proc Natl Acad Sci USA, 91 (1994) 2324-2328.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2324-2328
    • Winn, S.R.1    Hammang, J.P.2    Emerich, D.F.3
  • 73
    • 85030203796 scopus 로고
    • Albumin outflow into deep cervical lymph from different regions of rabbit brain
    • [73] Yamada, S., DePasquale, M., Patlak, C.S. et al., Albumin outflow into deep cervical lymph from different regions of rabbit brain, American Journal of Physiology, 240 (1991) F329-F336.
    • (1991) American Journal of Physiology , vol.240
    • Yamada, S.1    DePasquale, M.2    Patlak, C.S.3


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