Lipid peroxidation and cell death mechanisms in pulmonary epithelial cells induced by peroxynitrite and nitric oxide

Archives of Toxicology

Volumn 76, Issue 8, 2002, Pages 484-493

  Ho, Yuan Soon ^a,d   Liou, Hung Bin ^b   Lin, Jen Kun ^c   Jeng, Jiiang Huei ^c   Pan, Min Hsiung ^c   Lin, Yu Ping ^b   Guo, How Ran ^b   Ho, Sheng Yow ^b   Lee, Ching Chang ^b   Wang, Ying Jan ^b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d TAINAN SIN LAU HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Lipid peroxidation; Nitric oxide; Peroxynitrite

Indexed keywords

8 ISOPROSTAGLANDIN F2 ALPHA; BIOLOGICAL MARKER; CASPASE 9; CYTOCHROME C; NITRIC OXIDE; PEROXYNITRITE;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOSOL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME RELEASE; ENZYME SUBSTRATE; EPITHELIUM CELL; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LUNG ALVEOLUS EPITHELIUM; MITOSIS; NECROSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; TOXICOKINETICS;

ANIMALS; APOPTOSIS; CASPASES; CELL SURVIVAL; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; F2-ISOPROSTANES; HUMANS; INSTILLATION, DRUG; INTUBATION, INTRATRACHEAL; LIPID PEROXIDATION; LUNG; MALE; MEMBRANE POTENTIALS; NITRIC OXIDE; NITRIC OXIDE DONORS; PEROXYNITROUS ACID; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED;

EID: 18544375472     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-002-0373-3     Document Type: Article

References (56)

1. Biomarkers of apoptosis: Release of cytochrome c, activation of caspase-3, induction of 8-hydroxy-2'-deoxyguanosine, increased 3-nitrotyrosine, and alteration of p53 gene
2. Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
3. The cytotoxic effects of diesel exhaust particles on human pulmonary artery endothelial cells in vitro: Role of active oxygen species
4. The double-edged role of nitric oxide in brain function and superoxide-mediated injury
5. Apparent hydroxyl radical production by peroxynitrite, implications for endothelial injury from nitric oxide and superoxide
6. Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite
7. A mitochondrial perspective on cell death
8. Asbestos-induced lung diseases
9. Comparative toxicity of nitric oxide and peroxynitrite to E. coli
10. Nitric oxide: Foe or friend to the injured brain?
11. Biological consequences of general environmental contaminants
12. Oxidative stress and antioxidants at biosurfaces: Plants, skin, and respiratory tract surfaces
13. 2α and platelet activation in diabetes mellitus: Effects of improved metabolic control and vitamin E supplementation
14. Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi
15. Molecular mechanism of damage by excess nitrogen oxides nitration of tyrosine by gas-phase cigarette smoke
16. On the mechanism of NO release from sydnonimines
17. Reactive oxygen intermediates as regulators of TNF-α production in rat lung inflammation induced by silica
18. Mitochondria and apoptosis
19. Mitochondria and apoptosis
20. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury
21. Cell cycle specificity of apoptosis during treatment of leukaemias
22. Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide
23. The reaction of NO with superoxide
24. Peroxynitrite formation from macrophage-derived nitric oxide
25. Reactive species in ischemic rat lung injury: Contribution of peroxynitrite
26. Mitochondrial control of apoptosis
27. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
28. Health problems of residents along heavy-traffic roads
29. Lipid peroxidation and tissue damage
30. Role of mitochondria and caspases in vitamin D-mediated apoptosis of MCF-7 breast cancer cells
31. Nitric oxide as a secretory product of mammalian cells
32. Chronic infections and inflammatory processes as cancer risk factors: Possible role of nitric oxide in carcinogenesis
33. Traffic-related air pollution: Exposure and health effects in Copenhagen street cleaners and cemetery workers
34. 2-isoprostanes: Sensitive and specific non-invasive indices of lipid peroxidation in vivo
35. Oxidant generation and lung injury after particulate air pollutant exposure increased with the concentration of associated metals
36. Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
37. Production of nitric oxide and other iron-containing metabolites during the reductive metabolism of nitroprusside by microsomes and by thiols
38. Cytochrome c: Can't live with it - Can't live without it
39. Different roles for nitrogen monoxide and peroxynitrite in lipid peroxidation induced by activated neutrophils
40. Lipid peroxidation products and antioxidants in human disease
41. Nitric oxide-related oxidants in acute lung injury
42. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives
43. Different mechanisms between premitotic apoptosis and postmitotic apoptosis in X-irradiated U937 cells
44. 2-) with L-ascorbic acid
45. 2α in rats
46. Effect of exogenous and endogenous nitric oxide on mitochondrial respiration in rat hepatocytes
47. Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite
48. Interactions of human blood plasma with hydrogen peroxide and hypochlorous acid
49. Nitric oxide and its role in lipid peroxidation
50. Oxidative stress and liver toxicity in rats and human hepatoma cell line induced by pentachlorophenol and its major metabolite tetrachlorohydroquinone
51. Mechanisms of the antioxidant effects of nitric oxide
52. Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia
53. The mitochondrion in apoptosis: How Pandora's box opens
54. Bactericidal activity of peroxynitrite
55. Contribution of reactive oxygen and nitrogen species to particulate-induced lung injury
56. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3