Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5′-GTgG-3′ sequence: Destabilization of two base pairs at the lesion site

Nucleic Acids Research

Volumn 38, Issue 2, 2009, Pages 428-440

  Brown, Kyle L ^a   Roginskaya, Marina ^b   Zou, Yue ^b   Altamirano, Alvin ^c   Basu, Ashis K ^c   Stone, Michael P ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b East Tennessee State University   (United States)

^c UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIHYDRO 5,6 DIHYDROXYTHYMINE; BACTERIAL PROTEIN; GLYCOL; PROTEIN UVRA; PROTEIN UVRABC; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP A PROTEIN; XERODERMA PIGMENTOSUM GROUP C PROTEIN; DEOXYRIBONUCLEASE; DNA; DNA BINDING PROTEIN; DRUG DERIVATIVE; ENDODEOXYRIBONUCLEASE UVRABC; ESCHERICHIA COLI PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTON; RAD23B PROTEIN, HUMAN; THYMINE; XPA PROTEIN, HUMAN;

ARTICLE; BASE PAIRING; CIS TRANS ISOMERISM; DNA BASE COMPOSITION; DNA DAMAGE; DNA SEQUENCE; EXCISION REPAIR; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR STABILITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE; NUCLEOTIDE SEQUENCE; STEREOISOMERISM;

ESCHERICHIA COLI;

BASE PAIRING; BASE SEQUENCE; BINDING SITES; DNA; DNA DAMAGE; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; ESCHERICHIA COLI PROTEINS; HUMANS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTONS; STEREOISOMERISM; THYMINE; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

EID: 77449106429     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp844     Document Type: Article

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