-
1
-
-
33750619845
-
How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?
-
Antignani, A., and R. J. Youle. 2006. How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane? Curr. Opin. Cell Biol. 18:685-689.
-
(2006)
Curr. Opin. Cell Biol
, vol.18
, pp. 685-689
-
-
Antignani, A.1
Youle, R.J.2
-
2
-
-
34247895697
-
Voltage-dependent anion channels are dispensable for mitochondrialdependent cell death
-
Baines, C. P., R. A. Kaiser, T. Sheiko, W. J. Craigen, and J. D. Molkentin. 2007. Voltage-dependent anion channels are dispensable for mitochondrialdependent cell death. Nat. Cell Biol. 9:550-555.
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 550-555
-
-
Baines, C.P.1
Kaiser, R.A.2
Sheiko, T.3
Craigen, W.J.4
Molkentin, J.D.5
-
3
-
-
33745167654
-
The role of NF-κB-1 and NF-κB-2-mediated resistance to apoptosis in lymphomas
-
Bernal-Mizrachi, L., C. M. Lovly, and L. Ratner. 2006. The role of NF-κB-1 and NF-κB-2-mediated resistance to apoptosis in lymphomas. Proc. Natl. Acad. Sci. U. S. A. 103:9220-9225.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 9220-9225
-
-
Bernal-Mizrachi, L.1
Lovly, C.M.2
Ratner, L.3
-
4
-
-
0042697098
-
Infection of human urethral epithelium with Neisseria gonorrhoeae elicits an upregulation of host anti-apoptotic factors and protects cells from staurosporineinduced apoptosis
-
Binnicker, M. J., R. D. Williams, and M. A. Apicella. 2003. Infection of human urethral epithelium with Neisseria gonorrhoeae elicits an upregulation of host anti-apoptotic factors and protects cells from staurosporineinduced apoptosis. Cell. Microbiol. 5:549-560.
-
(2003)
Cell. Microbiol
, vol.5
, pp. 549-560
-
-
Binnicker, M.J.1
Williams, R.D.2
Apicella, M.A.3
-
5
-
-
7044237192
-
Gonococcal porin IB activates NF-kappaB in human urethral epithelium and increases the expression of host antiapoptotic factors
-
Binnicker, M. J., R. D. Williams, and M. A. Apicella. 2004. Gonococcal porin IB activates NF-kappaB in human urethral epithelium and increases the expression of host antiapoptotic factors. Infect. Immun. 72:6408-6417.
-
(2004)
Infect. Immun
, vol.72
, pp. 6408-6417
-
-
Binnicker, M.J.1
Williams, R.D.2
Apicella, M.A.3
-
6
-
-
0343765810
-
Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NFkappaB
-
Bork, P. M., M. L. Schmitz, M. Kuhnt, C. Escher, and M. Heinrich. 1997. Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NFkappaB. FEBS Lett. 402:85-90.
-
(1997)
FEBS Lett
, vol.402
, pp. 85-90
-
-
Bork, P.M.1
Schmitz, M.L.2
Kuhnt, M.3
Escher, C.4
Heinrich, M.5
-
7
-
-
0034682695
-
Apoptosis. Mitochondria - the death signal integrators
-
Brenner, C., and G. Kroemer. 2000. Apoptosis. Mitochondria - the death signal integrators. Science 289:1150-1151.
-
(2000)
Science
, vol.289
, pp. 1150-1151
-
-
Brenner, C.1
Kroemer, G.2
-
8
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
Budihardjo, I., H. Oliver, M. Lutter, X. Luo, and X. Wang. 1999. Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15:269-290.
-
(1999)
Annu. Rev. Cell Dev. Biol
, vol.15
, pp. 269-290
-
-
Budihardjo, I.1
Oliver, H.2
Lutter, M.3
Luo, X.4
Wang, X.5
-
9
-
-
0033621956
-
The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
-
Chen, C., L. C. Edelstein, and C. Gelinas. 2000. The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol. Cell. Biol. 20:2687-2695.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 2687-2695
-
-
Chen, C.1
Edelstein, L.C.2
Gelinas, C.3
-
10
-
-
0033574415
-
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
-
Chow, J. C., D. W. Young, D. T. Golenbock, W. J. Christ, and F. Gusovsky. 1999. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem. 274:10689-10692.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 10689-10692
-
-
Chow, J.C.1
Young, D.W.2
Golenbock, D.T.3
Christ, W.J.4
Gusovsky, F.5
-
11
-
-
34248348720
-
Shigella flexneri inhibits staurosporine-induced apoptosis in epithelial cells
-
Clark, C. S., and A. T. Maurelli. 2007. Shigella flexneri inhibits staurosporine-induced apoptosis in epithelial cells. Infect. Immun. 75:2531-2539.
-
(2007)
Infect. Immun
, vol.75
, pp. 2531-2539
-
-
Clark, C.S.1
Maurelli, A.T.2
-
12
-
-
0029685882
-
VDAC, a channel in the outer mitochondrial membrane
-
Colombini, M., E. Blachly-Dyson, and M. Forte. 1996. VDAC, a channel in the outer mitochondrial membrane. Ion Channels 4:169-202.
-
(1996)
Ion Channels
, vol.4
, pp. 169-202
-
-
Colombini, M.1
Blachly-Dyson, E.2
Forte, M.3
-
13
-
-
2642513875
-
Neisseria meningitidis-induced death of cerebrovascular endothelium: Mechanisms triggering transcriptional activation of inducible nitric oxide synthase
-
Constantin, D., A. Cordenier, K. Robinson, D. A. Ala'Aldeen, and S. Murphy. 2004. Neisseria meningitidis-induced death of cerebrovascular endothelium: mechanisms triggering transcriptional activation of inducible nitric oxide synthase. J. Neurochem. 89:1166-1174.
-
(2004)
J. Neurochem
, vol.89
, pp. 1166-1174
-
-
Constantin, D.1
Cordenier, A.2
Robinson, K.3
Ala'Aldeen, D.A.4
Murphy, S.5
-
14
-
-
0032479983
-
Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
-
Deak, M., A. D. Clifton, L. M. Lucocq, and D. R. Alessi. 1998. Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J. 17:4426-4441.
-
(1998)
EMBO J
, vol.17
, pp. 4426-4441
-
-
Deak, M.1
Clifton, A.D.2
Lucocq, L.M.3
Alessi, D.R.4
-
15
-
-
67249114315
-
-
Deghmane, A. E., C. Veckerle, D. Giorgini, E. Hong, C. Ruckly, and M. K. Taha. 2009. Differential modulation of TNF-alpha-induced apoptosis by Neisseria meningitidis. PLoS Pathog. 5:e1000405.
-
Deghmane, A. E., C. Veckerle, D. Giorgini, E. Hong, C. Ruckly, and M. K. Taha. 2009. Differential modulation of TNF-alpha-induced apoptosis by Neisseria meningitidis. PLoS Pathog. 5:e1000405.
-
-
-
-
16
-
-
0033403563
-
Endogenous inhibitors of caspases
-
Deveraux, Q. L., H. R. Stennicke, G. S. Salvesen, and J. C. Reed. 1999. Endogenous inhibitors of caspases. J. Clin. Immunol. 19:388-398.
-
(1999)
J. Clin. Immunol
, vol.19
, pp. 388-398
-
-
Deveraux, Q.L.1
Stennicke, H.R.2
Salvesen, G.S.3
Reed, J.C.4
-
17
-
-
0032543597
-
Functional dissection of Bfl-1, a Bcl-2 homolog: Anti-apoptosis, oncogene-cooperation and cell proliferation activities
-
D'Sa-Eipper, C., and G. Chinnadurai. 1998. Functional dissection of Bfl-1, a Bcl-2 homolog: anti-apoptosis, oncogene-cooperation and cell proliferation activities. Oncogene 16:3105-3114.
-
(1998)
Oncogene
, vol.16
, pp. 3105-3114
-
-
D'Sa-Eipper, C.1
Chinnadurai, G.2
-
18
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du, C., M. Fang, Y. Li, L. Li, and X. Wang. 2000. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102:33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
19
-
-
0037384877
-
NF-kappa B-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bfl-1/A1
-
Edelstein, L. C., L. Lagos, M. Simmons, H. Tirumalai, and C. Gelinas. 2003. NF-kappa B-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bfl-1/A1. Mol. Cell. Biol. 23:2749-2761.
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 2749-2761
-
-
Edelstein, L.C.1
Lagos, L.2
Simmons, M.3
Tirumalai, H.4
Gelinas, C.5
-
20
-
-
0032536526
-
Inhibition of apoptosis in chlamydia-infected cells: Blockade of mitochondrial cytochrome c release and caspase activation
-
Fan, T., H. Lu, H. Hu, L. Shi, G. A. McClarty, D. M. Nance, A. H. Greenberg, and G. Zhong. 1998. Inhibition of apoptosis in chlamydia-infected cells: blockade of mitochondrial cytochrome c release and caspase activation. J. Exp. Med. 187:487-496.
-
(1998)
J. Exp. Med
, vol.187
, pp. 487-496
-
-
Fan, T.1
Lu, H.2
Hu, H.3
Shi, L.4
McClarty, G.A.5
Nance, D.M.6
Greenberg, A.H.7
Zhong, G.8
-
21
-
-
0036499128
-
Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of Toll-like receptor 4-mediated signaling
-
Fichorova, R. N., A. O. Cronin, E. Lien, D. J. Anderson, and R. R. Ingalls. 2002. Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of Toll-like receptor 4-mediated signaling. J. Immunol. 168:2424-2432.
-
(2002)
J. Immunol
, vol.168
, pp. 2424-2432
-
-
Fichorova, R.N.1
Cronin, A.O.2
Lien, E.3
Anderson, D.J.4
Ingalls, R.R.5
-
22
-
-
0034773537
-
Characterization of antiapoptotic activities of Chlamydia pneumoniae in human cells
-
Fischer, S. F., C. Schwarz, J. Vier, and G. Hacker. 2001. Characterization of antiapoptotic activities of Chlamydia pneumoniae in human cells. Infect. Immun. 69:7121-7129.
-
(2001)
Infect. Immun
, vol.69
, pp. 7121-7129
-
-
Fischer, S.F.1
Schwarz, C.2
Vier, J.3
Hacker, G.4
-
23
-
-
69049103161
-
Neisseria gonorrhoeae infection protects human endocervical epithelial cells from apoptosis via expression of host antiapoptotic proteins
-
Follows, S. A., J. Murlidharan, P. Massari, L. M. Wetzler, and C. A. Genco. 2009. Neisseria gonorrhoeae infection protects human endocervical epithelial cells from apoptosis via expression of host antiapoptotic proteins. Infect. Immun. 77:3602-3610.
-
(2009)
Infect. Immun
, vol.77
, pp. 3602-3610
-
-
Follows, S.A.1
Murlidharan, J.2
Massari, P.3
Wetzler, L.M.4
Genco, C.A.5
-
24
-
-
0037302849
-
Apoptosis pathways: Turned on their heads?
-
Fulda, S., and K. M. Debatin. 2003. Apoptosis pathways: turned on their heads? Drug Resist. Updates 6:1-3.
-
(2003)
Drug Resist. Updates
, vol.6
, pp. 1-3
-
-
Fulda, S.1
Debatin, K.M.2
-
25
-
-
34247895699
-
Mitochondrial apoptosis without VDAC
-
Galluzzi, L., and G. Kroemer. 2007. Mitochondrial apoptosis without VDAC. Nat. Cell Biol. 9:487-489.
-
(2007)
Nat. Cell Biol
, vol.9
, pp. 487-489
-
-
Galluzzi, L.1
Kroemer, G.2
-
26
-
-
20444430478
-
Apoptotic pathways: Ten minutes to dead
-
Green, D. R. 2005. Apoptotic pathways: ten minutes to dead. Cell 121:671-674.
-
(2005)
Cell
, vol.121
, pp. 671-674
-
-
Green, D.R.1
-
27
-
-
35948990447
-
IFNgamma amplifies NFkappaB-dependent Neisseria meningitidis invasion of epithelial cells via specific upregulation of CEA-related cell adhesion molecule 1
-
Griffiths, N. J., C. J. Bradley, R. S. Heyderman, and M. Virji. 2007. IFNgamma amplifies NFkappaB-dependent Neisseria meningitidis invasion of epithelial cells via specific upregulation of CEA-related cell adhesion molecule 1. Cell. Microbiol. 9:2968-2983.
-
(2007)
Cell. Microbiol
, vol.9
, pp. 2968-2983
-
-
Griffiths, N.J.1
Bradley, C.J.2
Heyderman, R.S.3
Virji, M.4
-
28
-
-
0033981935
-
In vitro Brucella suis infection prevents the programmed cell death of human monocytic cells
-
Gross, A., A. Terraza, S. Ouahrani-Bettache, J. P. Liautard, and J. Dornand. 2000. In vitro Brucella suis infection prevents the programmed cell death of human monocytic cells. Infect. Immun. 68:342-351.
-
(2000)
Infect. Immun
, vol.68
, pp. 342-351
-
-
Gross, A.1
Terraza, A.2
Ouahrani-Bettache, S.3
Liautard, J.P.4
Dornand, J.5
-
29
-
-
0032473405
-
B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells
-
Grumont, R. J., I. J. Rourke, L. A. O'Reilly, A. Strasser, K. Miyake, W. Sha, and S. Gerondakis. 1998. B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells. J. Exp. Med. 187:663-674.
-
(1998)
J. Exp. Med
, vol.187
, pp. 663-674
-
-
Grumont, R.J.1
Rourke, I.J.2
O'Reilly, L.A.3
Strasser, A.4
Miyake, K.5
Sha, W.6
Gerondakis, S.7
-
30
-
-
0037198274
-
NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells
-
Heckman, C. A., J. W. Mehew, and L. M. Boxer. 2002. NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells. Oncogene 21:3898-3908.
-
(2002)
Oncogene
, vol.21
, pp. 3898-3908
-
-
Heckman, C.A.1
Mehew, J.W.2
Boxer, L.M.3
-
31
-
-
34848820894
-
Dynamics of Neisseria gonorrhoeae attachment: Microcolony development, cortical plaque formation, and cytoprotection
-
Higashi, D. L., S. W. Lee, A. Snyder, N. J. Weyand, A. Bakke, and M. So. 2007. Dynamics of Neisseria gonorrhoeae attachment: microcolony development, cortical plaque formation, and cytoprotection. Infect. Immun. 75: 4743-4753.
-
(2007)
Infect. Immun
, vol.75
, pp. 4743-4753
-
-
Higashi, D.L.1
Lee, S.W.2
Snyder, A.3
Weyand, N.J.4
Bakke, A.5
So, M.6
-
32
-
-
0030902592
-
Association of antibodies to Chlamydia trachomatis heat-shock protein 60 kD with chronic nongonococcal urethritis
-
Horner, P. J., D. Cain, M. McClure, B. J. Thomas, C. Gilroy, M. Ali, J. N. Weber, and D. Taylor-Robinson. 1997. Association of antibodies to Chlamydia trachomatis heat-shock protein 60 kD with chronic nongonococcal urethritis. Clin. Infect. Dis. 24:653-660.
-
(1997)
Clin. Infect. Dis
, vol.24
, pp. 653-660
-
-
Horner, P.J.1
Cain, D.2
McClure, M.3
Thomas, B.J.4
Gilroy, C.5
Ali, M.6
Weber, J.N.7
Taylor-Robinson, D.8
-
33
-
-
46249115222
-
Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim
-
Howie, H. L., S. L. Shiflett, and M. So. 2008. Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim. Infect. Immun. 76:2715-2721.
-
(2008)
Infect. Immun
, vol.76
, pp. 2715-2721
-
-
Howie, H.L.1
Shiflett, S.L.2
So, M.3
-
34
-
-
0029085935
-
Signalling downstream of activated mammalian Notch
-
Jarriault, S., C. Brou, F. Logeat, E. H. Schroeter, R. Kopan, and A. Israel. 1995. Signalling downstream of activated mammalian Notch. Nature 377: 355-358.
-
(1995)
Nature
, vol.377
, pp. 355-358
-
-
Jarriault, S.1
Brou, C.2
Logeat, F.3
Schroeter, E.H.4
Kopan, R.5
Israel, A.6
-
35
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin, M., and A. Lin. 2002. NF-kappaB at the crossroads of life and death. Nat. Immunol. 3:221-227.
-
(2002)
Nat. Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
36
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck, R. M., E. Bossy-Wetzel, D. R. Green, and D. D. Newmeyer. 1997. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275:1132-1136.
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
37
-
-
33847286488
-
Cleavage of p65/RelA of the NF-kappaB pathway by Chlamydia
-
Lad, S. P., J. Li, C. J. da Silva, Q. Pan, S. Gadwal, R. J. Ulevitch, and E. Li. 2007. Cleavage of p65/RelA of the NF-kappaB pathway by Chlamydia. Proc. Natl. Acad. Sci. U. S. A. 104:2933-2938.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A
, vol.104
, pp. 2933-2938
-
-
Lad, S.P.1
Li, J.2
da Silva, C.J.3
Pan, Q.4
Gadwal, S.5
Ulevitch, R.J.6
Li, E.7
-
38
-
-
0033529416
-
NFkappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes
-
Lee, H. H., H. Dadgostar, Q. Cheng, J. Shu, and G. Cheng. 1999. NFkappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 96:9136-9141.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A
, vol.96
, pp. 9136-9141
-
-
Lee, H.H.1
Dadgostar, H.2
Cheng, Q.3
Shu, J.4
Cheng, G.5
-
39
-
-
0036728834
-
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
-
Letai, A., M. C. Bassik, L. D. Walensky, M. D. Sorcinelli, S. Weiler, and S. J. Korsmeyer. 2002. Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2:183-192.
-
(2002)
Cancer Cell
, vol.2
, pp. 183-192
-
-
Letai, A.1
Bassik, M.C.2
Walensky, L.D.3
Sorcinelli, M.D.4
Weiler, S.5
Korsmeyer, S.J.6
-
40
-
-
48249092267
-
Bcl-2 family members: Dual regulators of apoptosis and autophagy
-
Levine, B., S. Sinha, and G. Kroemer. 2008. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 4:600-606.
-
(2008)
Autophagy
, vol.4
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, G.3
-
41
-
-
0033611145
-
ER/Golgi intermediates acquire Golgi enzymes by brefeldin A-sensitive retrograde transport in vitro
-
Lin, C. C., H. D. Love, J. N. Gushue, J. J. Bergeron, and J. Ostermann. 1999. ER/Golgi intermediates acquire Golgi enzymes by brefeldin A-sensitive retrograde transport in vitro. J. Cell Biol. 147:1457-1472.
-
(1999)
J. Cell Biol
, vol.147
, pp. 1457-1472
-
-
Lin, C.C.1
Love, H.D.2
Gushue, J.N.3
Bergeron, J.J.4
Ostermann, J.5
-
42
-
-
33748479935
-
Meningococcal adhesion suppresses proapoptotic gene expression and promotes expression of genes supporting early embryonic and cytoprotective signaling of human endothelial cells
-
Linhartova, I., M. Basler, J. Ichikawa, V. Pelicic, R. Osicka, S. Lory, X. Nassif, and P. Sebo. 2006. Meningococcal adhesion suppresses proapoptotic gene expression and promotes expression of genes supporting early embryonic and cytoprotective signaling of human endothelial cells. FEMS Microbiol. Lett. 263:109-118.
-
(2006)
FEMS Microbiol. Lett
, vol.263
, pp. 109-118
-
-
Linhartova, I.1
Basler, M.2
Ichikawa, J.3
Pelicic, V.4
Osicka, R.5
Lory, S.6
Nassif, X.7
Sebo, P.8
-
43
-
-
38349075841
-
The PorB porin from commensal Neisseria lactamica induces Th1 and Th2 immune responses to ovalbumin in mice and is a potential immune adjuvant
-
Liu, X., L. M. Wetzler, and P. Massari. 2008. The PorB porin from commensal Neisseria lactamica induces Th1 and Th2 immune responses to ovalbumin in mice and is a potential immune adjuvant. Vaccine 26:786-796.
-
(2008)
Vaccine
, vol.26
, pp. 786-796
-
-
Liu, X.1
Wetzler, L.M.2
Massari, P.3
-
44
-
-
38349107623
-
The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells
-
Longo, P. G., L. Laurenti, S. Gobessi, S. Sica, G. Leone, and D. G. Efremov. 2008. The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells. Blood 111:846-855.
-
(2008)
Blood
, vol.111
, pp. 846-855
-
-
Longo, P.G.1
Laurenti, L.2
Gobessi, S.3
Sica, S.4
Leone, G.5
Efremov, D.G.6
-
45
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo, X., I. Budihardjo, H. Zou, C. Slaughter, and X. Wang. 1998. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94:481-490.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
46
-
-
47049108203
-
Role of protein tyrosine kinase and Erk1/2 activities in the Toll-like receptor 2-induced cellular activation of murine B cells by neisserial porin
-
MacLeod, H., N. Bhasin, and L. M. Wetzler. 2008. Role of protein tyrosine kinase and Erk1/2 activities in the Toll-like receptor 2-induced cellular activation of murine B cells by neisserial porin. Clin. Vaccine Immunol. 15: 630-637.
-
(2008)
Clin. Vaccine Immunol
, vol.15
, pp. 630-637
-
-
MacLeod, H.1
Bhasin, N.2
Wetzler, L.M.3
-
47
-
-
0032550363
-
The permeability transition pore complex: A target for apoptosis regulation by caspases and Bcl-2-related proteins
-
Marzo, I., C. Brenner, N. Zamzami, S. A. Susin, G. Beutner, D. Brdiczka, R. My, Z. H. Xie, J. C. Reed, and G. Kroemer. 1998. The permeability transition pore complex: a target for apoptosis regulation by caspases and Bcl-2-related proteins. J. Exp. Med. 187:1261-1271.
-
(1998)
J. Exp. Med
, vol.187
, pp. 1261-1271
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
Susin, S.A.4
Beutner, G.5
Brdiczka, D.6
My, R.7
Xie, Z.H.8
Reed, J.C.9
Kroemer, G.10
-
48
-
-
0037083638
-
Cutting edge: Immune stimulation by neisserial porins is Toll-like receptor 2 and MyD88 dependent
-
Massari, P., P. Henneke, Y. Ho, E. Latz, D. T. Golenbock, and L. M. Wetzler. 2002. Cutting edge: immune stimulation by neisserial porins is Toll-like receptor 2 and MyD88 dependent. J. Immunol. 168:1533-1537.
-
(2002)
J. Immunol
, vol.168
, pp. 1533-1537
-
-
Massari, P.1
Henneke, P.2
Ho, Y.3
Latz, E.4
Golenbock, D.T.5
Wetzler, L.M.6
-
49
-
-
0034255514
-
Neisseria meningitidis porin PorB interacts with mitochondria and protects cells from apoptosis
-
Massari, P., Y. Ho, and L. M. Wetzler. 2000. Neisseria meningitidis porin PorB interacts with mitochondria and protects cells from apoptosis. Proc. Natl. Acad. Sci. U. S. A. 97:9070-9075.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A
, vol.97
, pp. 9070-9075
-
-
Massari, P.1
Ho, Y.2
Wetzler, L.M.3
-
50
-
-
0037303755
-
Neisserial PorB is translocated to the mitochondria of HeLa cells infected with Neisseria meningitidis and protects cells from apoptosis
-
Massari, P., C. A. King, A. Y. Ho, and L. M. Wetzler. 2003. Neisserial PorB is translocated to the mitochondria of HeLa cells infected with Neisseria meningitidis and protects cells from apoptosis. Cell. Microbiol. 5:99-109.
-
(2003)
Cell. Microbiol
, vol.5
, pp. 99-109
-
-
Massari, P.1
King, C.A.2
Ho, A.Y.3
Wetzler, L.M.4
-
51
-
-
27644471232
-
Improved purification of native meningococcal porin PorB and studies on its structure/ function
-
Massari, P., C. A. King, H. Macleod, and L. M. Wetzler. 2005. Improved purification of native meningococcal porin PorB and studies on its structure/ function. Protein Expr. Purif. 44:136-146.
-
(2005)
Protein Expr. Purif
, vol.44
, pp. 136-146
-
-
Massari, P.1
King, C.A.2
Macleod, H.3
Wetzler, L.M.4
-
52
-
-
32044471573
-
Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling
-
Massari, P., A. Visintin, J. Gunawardana, K. A. Halmen, C. A. King, D. T. Golenbock, and L. M. Wetzler. 2006. Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling. J. Immunol. 176:2373-2380.
-
(2006)
J. Immunol
, vol.176
, pp. 2373-2380
-
-
Massari, P.1
Visintin, A.2
Gunawardana, J.3
Halmen, K.A.4
King, C.A.5
Golenbock, D.T.6
Wetzler, L.M.7
-
53
-
-
49649111406
-
Airway epithelial cells modify immune responses by inducing an anti-inflammatory microenvironment
-
Mayer, A. K., H. Bartz, F. Fey, L. M. Schmidt, and A. H. Dalpke. 2008. Airway epithelial cells modify immune responses by inducing an anti-inflammatory microenvironment. Eur. J. Immunol. 38:1689-1699.
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 1689-1699
-
-
Mayer, A.K.1
Bartz, H.2
Fey, F.3
Schmidt, L.M.4
Dalpke, A.H.5
-
54
-
-
0030868990
-
Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers
-
Molinari, M., C. Galli, N. Norais, J. L. Telford, R. Rappuoli, J. P. Luzio, and C. Montecucco. 1997. Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers. J. Biol. Chem. 272:25339-25344.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 25339-25344
-
-
Molinari, M.1
Galli, C.2
Norais, N.3
Telford, J.L.4
Rappuoli, R.5
Luzio, J.P.6
Montecucco, C.7
-
55
-
-
33646909086
-
Infection of human fallopian tube epithelial cells with Neisseria gonorrhoeae protects cells from tumor necrosis factor alpha-induced apoptosis
-
Morales, P., P. Reyes, M. Vargas, M. Rios, M. Imarai, H. Cardenas, H. Croxatto, P. Orihuela, R. Vargas, J. Fuhrer, J. E. Heckels, M. Christodoulides, and L. Velasquez. 2006. Infection of human fallopian tube epithelial cells with Neisseria gonorrhoeae protects cells from tumor necrosis factor alpha-induced apoptosis. Infect. Immun. 74:3643-3650.
-
(2006)
Infect. Immun
, vol.74
, pp. 3643-3650
-
-
Morales, P.1
Reyes, P.2
Vargas, M.3
Rios, M.4
Imarai, M.5
Cardenas, H.6
Croxatto, H.7
Orihuela, P.8
Vargas, R.9
Fuhrer, J.10
Heckels, J.E.11
Christodoulides, M.12
Velasquez, L.13
-
56
-
-
0344851588
-
Lipopolysaccharide from the periodontal pathogen Porphyromonas gingivalis prevents apoptosis of HL60-derived neutrophils in vitro
-
Murray, D. A., and J. M. Wilton. 2003. Lipopolysaccharide from the periodontal pathogen Porphyromonas gingivalis prevents apoptosis of HL60-derived neutrophils in vitro. Infect. Immun. 71:7232-7235.
-
(2003)
Infect. Immun
, vol.71
, pp. 7232-7235
-
-
Murray, D.A.1
Wilton, J.M.2
-
57
-
-
0030892234
-
Apoptosis by death factor
-
Nagata, S. 1997. Apoptosis by death factor. Cell 88:355-365.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
58
-
-
0035948261
-
Inhibition of epithelial cell apoptosis by Porphyromonas gingivalis
-
Nakhjiri, S. F., Y. Park, O. Yilmaz, W. O. Chung, K. Watanabe, A. El Sabaeny, K. Park, and R. J. Lamont. 2001. Inhibition of epithelial cell apoptosis by Porphyromonas gingivalis. FEMS Microbiol. Lett. 200:145-149.
-
(2001)
FEMS Microbiol. Lett
, vol.200
, pp. 145-149
-
-
Nakhjiri, S.F.1
Park, Y.2
Yilmaz, O.3
Chung, W.O.4
Watanabe, K.5
El Sabaeny, A.6
Park, K.7
Lamont, R.J.8
-
59
-
-
1842287946
-
Neisseria gonorrhoeae epithelial cell interaction leads to the activation of the transcription factors nuclear factor kappaB and activator protein 1 and the induction of inflammatory cytokines
-
Naumann, M., S. Wessler, C. Bartsch, B. Wieland, and T. F. Meyer. 1997. Neisseria gonorrhoeae epithelial cell interaction leads to the activation of the transcription factors nuclear factor kappaB and activator protein 1 and the induction of inflammatory cytokines. J. Exp. Med. 186:247-258.
-
(1997)
J. Exp. Med
, vol.186
, pp. 247-258
-
-
Naumann, M.1
Wessler, S.2
Bartsch, C.3
Wieland, B.4
Meyer, T.F.5
-
60
-
-
33746806643
-
Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJ kappa-dependent pathway
-
Pegman, P. M., S. M. Smith, B. N. D'Souza, S. T. Loughran, S. Maier, B. Kempkes, P. A. Cahill, M. J. Simmons, C. Gelinas, and D. Walls. 2006. Epstein-Barr virus nuclear antigen 2 trans-activates the cellular antiapoptotic bfl-1 gene by a CBF1/RBPJ kappa-dependent pathway. J. Virol. 80: 8133-8144.
-
(2006)
J. Virol
, vol.80
, pp. 8133-8144
-
-
Pegman, P.M.1
Smith, S.M.2
D'Souza, B.N.3
Loughran, S.T.4
Maier, S.5
Kempkes, B.6
Cahill, P.A.7
Simmons, M.J.8
Gelinas, C.9
Walls, D.10
-
61
-
-
51849159637
-
Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells
-
Rajalingam, K., M. Sharma, C. Lohmann, M. Oswald, O. Thieck, C. J. Froelich, and T. Rudel. 2008. Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells. PLoS ONE 3:e3102.
-
(2008)
PLoS ONE
, vol.3
-
-
Rajalingam, K.1
Sharma, M.2
Lohmann, C.3
Oswald, M.4
Thieck, O.5
Froelich, C.J.6
Rudel, T.7
-
62
-
-
4544315971
-
Secreted proteins from Neisseria meningitidis mediate differential human gene expression and immune activation
-
Robinson, K., M. Taraktsoglou, K. S. Rowe, K. G. Wooldridge, and D. A. Ala'Aldeen. 2004. Secreted proteins from Neisseria meningitidis mediate differential human gene expression and immune activation. Cell. Microbiol. 6:927-938.
-
(2004)
Cell. Microbiol
, vol.6
, pp. 927-938
-
-
Robinson, K.1
Taraktsoglou, M.2
Rowe, K.S.3
Wooldridge, K.G.4
Ala'Aldeen, D.A.5
-
63
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi, C., S. Fulda, A. Srinivasan, C. Friesen, F. Li, K. J. Tomaselli, K. M. Debatin, P. H. Krammer, and M. E. Peter. 1998. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 17:1675-1687.
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
-
64
-
-
39849108605
-
Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist
-
Simmons, M. J., G. Fan, W. X. Zong, K. Degenhardt, E. White, and C. Gelinas. 2008. Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist. Oncogene 27:1421-1428.
-
(2008)
Oncogene
, vol.27
, pp. 1421-1428
-
-
Simmons, M.J.1
Fan, G.2
Zong, W.X.3
Degenhardt, K.4
White, E.5
Gelinas, C.6
-
65
-
-
33749551671
-
Neisseria gonorrhoeae delays the onset of apoptosis in polymorphonuclear leukocytes
-
Simons, M. P., W. M. Nauseef, T. S. Griffith, and M. A. Apicella. 2006. Neisseria gonorrhoeae delays the onset of apoptosis in polymorphonuclear leukocytes. Cell. Microbiol. 8:1780-1790.
-
(2006)
Cell. Microbiol
, vol.8
, pp. 1780-1790
-
-
Simons, M.P.1
Nauseef, W.M.2
Griffith, T.S.3
Apicella, M.A.4
-
66
-
-
37849046992
-
Nod-like receptors: Cytosolic watchdogs for immunity against pathogens
-
Sirard, J. C., C. Vignal, R. Dessein, and M. Chamaillard. 2007. Nod-like receptors: cytosolic watchdogs for immunity against pathogens. PLoS Pathog. 3:e152.
-
(2007)
PLoS Pathog
, vol.3
-
-
Sirard, J.C.1
Vignal, C.2
Dessein, R.3
Chamaillard, M.4
-
67
-
-
0034908490
-
Transient expression of the Bcl-2 family member, A1-a, results in nuclear localization and resistance to staurosporine-induced apoptosis
-
Somogyi, R. D., Y. Wu, A. Orlofsky, and M. B. Prystowsky. 2001. Transient expression of the Bcl-2 family member, A1-a, results in nuclear localization and resistance to staurosporine-induced apoptosis. Cell Death Differ. 8:785-793.
-
(2001)
Cell Death Differ
, vol.8
, pp. 785-793
-
-
Somogyi, R.D.1
Wu, Y.2
Orlofsky, A.3
Prystowsky, M.B.4
-
68
-
-
1442359848
-
The interplay between the Bcl-2 family and death receptor-mediated apoptosis
-
Sprick, M. R., and H. Walczak. 2004. The interplay between the Bcl-2 family and death receptor-mediated apoptosis. Biochim. Biophys. Acta 1644:125-132.
-
(2004)
Biochim. Biophys. Acta
, vol.1644
, pp. 125-132
-
-
Sprick, M.R.1
Walczak, H.2
-
69
-
-
0033579810
-
Mitochondrial release of caspase-2 and -9 during the apoptotic process
-
Susin, S. A., H. K. Lorenzo, N. Zamzami, I. Marzo, C. Brenner, N. Larochette, M. C. Prevost, P. M. Alzari, and G. Kroemer. 1999. Mitochondrial release of caspase-2 and -9 during the apoptotic process. J. Exp. Med. 189:381-394.
-
(1999)
J. Exp. Med
, vol.189
, pp. 381-394
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Brenner, C.5
Larochette, N.6
Prevost, M.C.7
Alzari, P.M.8
Kroemer, G.9
-
70
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin, S. A., H. K. Lorenzo, N. Zamzami, I. Marzo, B. E. Snow, G. M. Brothers, J. Mangion, E. Jacotot, P. Costantini, M. Loeffler, N. Larochette, D. R. Goodlett, R. Aebersold, D. P. Siderovski, J. M. Penninger, and G. Kroemer. 1999. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397:441-446.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, N.11
Goodlett, D.R.12
Aebersold, R.13
Siderovski, D.P.14
Penninger, J.M.15
Kroemer, G.16
-
71
-
-
0030785790
-
The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
-
Susin, S. A., N. Zamzami, M. Castedo, E. Daugas, H. G. Wang, S. Geley, F. Fassy, J. C. Reed, and G. Kroemer. 1997. The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis. J. Exp. Med. 186:25-37.
-
(1997)
J. Exp. Med
, vol.186
, pp. 25-37
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
Daugas, E.4
Wang, H.G.5
Geley, S.6
Fassy, F.7
Reed, J.C.8
Kroemer, G.9
-
72
-
-
0034525413
-
VDAC regulation by the Bcl-2 family of proteins
-
Tsujimoto, Y., and S. Shimizu. 2000. VDAC regulation by the Bcl-2 family of proteins. Cell Death Differ. 7:1174-1181.
-
(2000)
Cell Death Differ
, vol.7
, pp. 1174-1181
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
73
-
-
29644438629
-
Inhibition of macrophage apoptosis by Neisseria meningitidis requires nitric oxide detoxification mechanisms
-
Tunbridge, A. J., T. M. Stevanin, M. Lee, H. M. Marriott, J. W. Moir, R. C. Read, and D. H. Dockrell. 2006. Inhibition of macrophage apoptosis by Neisseria meningitidis requires nitric oxide detoxification mechanisms. Infect. Immun. 74:729-733.
-
(2006)
Infect. Immun
, vol.74
, pp. 729-733
-
-
Tunbridge, A.J.1
Stevanin, T.M.2
Lee, M.3
Marriott, H.M.4
Moir, J.W.5
Read, R.C.6
Dockrell, D.H.7
-
74
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
Vander Heiden, M. G., N. S. Chandel, E. K. Williamson, P. T. Schumacker, and C. B. Thompson. 1997. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 91:627-637.
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
Schumacker, P.T.4
Thompson, C.B.5
-
75
-
-
0035086344
-
Differential gene expression during meningeal- meningococcal interaction: Evidence for self-defense and early release of cytokines and chemokines
-
Wells, D. B., P. J. Tighe, K. G. Wooldridge, K. Robinson, and D. A. Ala'Aldeen. 2001. Differential gene expression during meningeal- meningococcal interaction: evidence for self-defense and early release of cytokines and chemokines. Infect. Immun. 69:2718-2722.
-
(2001)
Infect. Immun
, vol.69
, pp. 2718-2722
-
-
Wells, D.B.1
Tighe, P.J.2
Wooldridge, K.G.3
Robinson, K.4
Ala'Aldeen, D.A.5
-
76
-
-
0037151030
-
Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit its collaboration with pro-apoptotic Bak or Bax
-
Werner, A. B., E. de Vries, S. W. Tait, I. Bontjer, and J. Borst. 2002. Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit its collaboration with pro-apoptotic Bak or Bax. J. Biol. Chem. 277:22781- 22788.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 22781-22788
-
-
Werner, A.B.1
de Vries, E.2
Tait, S.W.3
Bontjer, I.4
Borst, J.5
-
77
-
-
26844463593
-
The antiinflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappaB signaling, release of pro-inflammatory cytokines/chemokines and attenuates adhesion in late infection
-
Wessler, S., P. Muenzner, T. F. Meyer, and M. Naumann. 2005. The antiinflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappaB signaling, release of pro-inflammatory cytokines/chemokines and attenuates adhesion in late infection. Biol. Chem. 386:481-490.
-
(2005)
Biol. Chem
, vol.386
, pp. 481-490
-
-
Wessler, S.1
Muenzner, P.2
Meyer, T.F.3
Naumann, M.4
-
78
-
-
0034671803
-
Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses
-
Wyllie, D. H., E. Kiss-Toth, A. Visintin, S. C. Smith, S. Boussouf, D. M. Segal, G. W. Duff, and S. K. Dower. 2000. Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses. J. Immunol. 165:7125-7132.
-
(2000)
J. Immunol
, vol.165
, pp. 7125-7132
-
-
Wyllie, D.H.1
Kiss-Toth, E.2
Visintin, A.3
Smith, S.C.4
Boussouf, S.5
Segal, D.M.6
Duff, G.W.7
Dower, S.K.8
-
79
-
-
12444338487
-
NF-kappa B activation is not required for Chlamydia trachomatis inhibition of host epithelial cell apoptosis
-
Xiao, Y., Y. Zhong, H. Su, Z. Zhou, P. Chiao, and G. Zhong. 2005. NF-kappa B activation is not required for Chlamydia trachomatis inhibition of host epithelial cell apoptosis. J. Immunol. 174:1701-1708.
-
(2005)
J. Immunol
, vol.174
, pp. 1701-1708
-
-
Xiao, Y.1
Zhong, Y.2
Su, H.3
Zhou, Z.4
Chiao, P.5
Zhong, G.6
-
80
-
-
33750625916
-
Inhibition of staurosporine-induced activation of the proapoptotic multidomain Bcl-2 proteins Bax and Bak by three invasive chlamydial species
-
Zhong, Y., M. Weininger, M. Pirbhai, F. Dong, and G. Zhong. 2006. Inhibition of staurosporine-induced activation of the proapoptotic multidomain Bcl-2 proteins Bax and Bak by three invasive chlamydial species. J. Infect. 53:408-414.
-
(2006)
J. Infect
, vol.53
, pp. 408-414
-
-
Zhong, Y.1
Weininger, M.2
Pirbhai, M.3
Dong, F.4
Zhong, G.5
-
81
-
-
0033558215
-
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NFkappaB that blocks TNFalpha-induced apoptosis
-
Zong, W. X., L. C. Edelstein, C. Chen, J. Bash, and C. Gelinas. 1999. The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NFkappaB that blocks TNFalpha-induced apoptosis. Genes Dev. 13:382-387.
-
(1999)
Genes Dev
, vol.13
, pp. 382-387
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Zong, W.X.1
Edelstein, L.C.2
Chen, C.3
Bash, J.4
Gelinas, C.5
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