Pigmented creatine deposits in Amyotrophic Lateral Sclerosis central nervous system tissues identified by synchrotron Fourier Transform Infrared microspectroscopy and X-ray fluorescence spectromicroscopy

Neuroscience

Volumn 166, Issue 4, 2010, Pages 1119-1128

  Kastyak, M Z ^a,b   Szczerbowska Boruchowska, M ^a   Adamek, D ^c   Tomik, B ^c   Lankosz, M ^a   Gough, K M ^b  

^a AGH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Poland)

^b UNIVERSITY OF MANITOBA   (Canada)

^c JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Amyotrophic Lateral Sclerosis; creatine; FTIR; pigmented deposits; synchrotron; XRF

Indexed keywords

CALCIUM; COPPER; CREATINE; IRON; NEUROMELANIN; POTASSIUM; ZINC;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN STEM; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; INFRARED SPECTROSCOPY; MOTOR CORTEX; OXIDATIVE STRESS; PRIORITY JOURNAL; SPINAL CORD; SUBSTANTIA NIGRA; SYNCHROTRON; X RAY FLUORESCENCE;

AGED; AMYOTROPHIC LATERAL SCLEROSIS; BIOLOGICAL MARKERS; CENTRAL NERVOUS SYSTEM; CREATINE; ENERGY METABOLISM; FEMALE; FOURIER ANALYSIS; HUMANS; INCLUSION BODIES; MALE; MIDDLE AGED; NEURONS; OXIDATIVE STRESS; PIGMENTS, BIOLOGICAL; SPECTROMETRY, X-RAY EMISSION; SPECTROPHOTOMETRY, INFRARED; SYNCHROTRONS;

EID: 77349119581     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.01.017     Document Type: Article

References (56)

1. Adamek D., Tomik B., Pichor A., Kaluza J., and Szczudlik A. The heterogeneity of neuropathological changes in amyotrophic lateral sclerosis. A review of own autopsy material. Folia Neuropathol 40 3 (2002) 119-124
2. Benatar M. Lost in translation: treatment trials in the SOD1 mouse and in human ALS. Neurobiol Dis 26 1 (2008) 1-13
3. Blauw H.M., Veldink J.H., van Es M.A., van Vught P.W., Saris C.G.J., van der Zwaag B., Franke L., Burbach J.P.H., Wokke J.H., Ophoff R.A., and van den Berg L.H. Copy-number variation in sporadic amyotrophic lateral sclerosis: a genome-wide screen. Lancet Neurol 7 4 (2008) 319-326
4. Braissant O., Henry H., Loup M., Eilers B., and Bachmann C. Endogenous synthesis and transport of creatine in the rat brain: an in situ hybridization study. Brain Res Mol Brain Res 86 (2001) 193-201
5. Brooks B.R., Miller R.G., Swash M., and Munsat T.L. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 1 (2000) 293-299
6. Bruijn L.I., Miller T.M., and Cleveland D.W. Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 27 (2004) 723-749
7. Bunina T.L. On intracellular inclusions in familial amyotrophic lateral sclerosis. Zhurnal nevropatologii i psikhiatrii imeni SS. Korsakova (Moscow, Russia) 62 (1962) 1293-1299
8. Chou S.M., Taniguchi A., Wang H.S., and Festoff B.W. Serpin-serine protease-like complexes within neurofilament conglomerations of motoneurons in amyotrophic lateral sclerosis. J Neurol Sci 160 Suppl 1 (1998) S73-S79
9. Chwiej J. PhD thesis: Promieniowanie synchrotronowe w badaniach składu pierwiastkowego oraz zwia̧zkǒw organicznych w komǒrkach nerwowych dla wybranych schorzeń neurodegeneracyjnych (2007), University of Science and Technology, Krakow, Poland
10. Chwiej J., Szczerbowska-Boruchowska M., Wójcik S., Lankosz M., Chlebda M., Adamek D., Tomik B., Setkowicz Z., Falkenberg G., Stȩgowski Z., and Szczudlik A. Implementation of X-ray fluorescence microscopy for investigation of elemental abnormalities in central nervous system tissue. J Alloy Comp 401 (2005) 184-188
11. Double K.L., Zecca L., Costi P., Mauer M., Griesinger C., Ito S., Ben-Shachar D., Bringmann G., Fariello R.G., Riederer P., and Gerlach M. Structural characteristics of human substantia nigra neuromelanin and synthetic dopamine melanins. J Neurochem 75 6 (2000) 2583-2589
12. Dumas P., and Miller L. The use of synchrotron infrared microspectroscopy in biological and biomedical investigations. Vib Spectrosc 32 (2003) 3-21
13. Dupuis L., Corcia P., Fergani A., Gonzalez De Aguilar J.L., Bonnefont-Rousselot D., Bittar R., Seilhean D., Hauw J.J., Lacomblez L., Loeffler J.P., and Meininger V. Dyslipidemia is a protective factor in amyotrophic lateral sclerosis. Neurology 70 13 Pt 1 (2008) 1004-1009
14. Ellison D., Love S., Chimelli L., Harding B.N., Lowe J., and Vinters H.V. Neuropathology. A reference text of CNS pathology. 2nd ed. (2004), Mosby, New York
15. Gaeta A., and Hider R.C. The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy. Br J Pharmacol 146 8 (2005) 1041-1059
16. Gallant M., Rak M., Szeghalmi A., Del Bigio M.R., Westaway D., Yang J., Julian R., and Gough K.M. Focally elevated creatine detected in amyloid precursor protein (APP) transgenic mice and Alzheimer's disease brain tissue. J Biol Chem 281 1 (2006) 5-8
17. Gallant M. Infrared microspectroscopy of focally elevated creatine in brain tissue from amyloid precursor protein (APP) transgenic mice. M. Sc. Thesis (2008), University of Manitoba
18. Gonzalez de Aguilar J.L., Echaniz-Laguna A., Fergani A., Rene F., Meininger V., Loeffler J.P., and Dupuis L. Amyotrophic lateral sclerosis: all roads lead to Rome. J Neurochem 101 5 (2007) 1153-1160
19. Hemmer W., and Wallimann T. Functional aspects of creatine kinase in brain. Dev Neurosci 15 3-5 (1993) 249-260
20. Ince P.G., Clark B., Holton J., Revesz T., and Wharton S. Diseases of movement and system degenerations. In: Love S., Louis D.N., and Ellison D.W. (Eds). Greenfield's Neuropathology. 8th ed. (2008), Hodder Arnold, London, UK 889-1030
21. Kastyak M.Z. Master thesis: Zastosowanie synchrotronowej mikrospektroskopii w podczerwieni do analizy tkanek osrodkowego ukladu nerwowego czlowieka w chorobach neurodegeneracyjnych (2005), University of Science and Technology, Krakow, Poland
22. Klivenyi P., Ferrante R.J., Matthews R.T., Bogdanov M.B., Klein A.M., Andreassen O.A., Mueller G., Wermer M., Kaddurah-Daouk R., and Beal M.F. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat Med 5 (1999) 347-350
23. Klivenyi P., Kiaei M., Gardian G., Calingasan N.Y., and Beal M.F. Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurochem 88 3 (2004) 576-582
24. Kong J., and Xu Z. Massive mitochondrial degeneration in motor neuronstriggers the onset of amyotrophic lateral sclerosis in mice expressinga mutant SOD1. J Neurosci 18 (1998) 3241-3250
25. Lunardi G., Parodi A., Perasso L., Pohvozcheva A.V., and Scarrone S. The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds. Neuroscience 142 (2006) 991-997
26. Mattson M.P., Gleichmann M., and Cheng A. Mitochondria in neuroplasticity and neurological disorders. Neuron 60 5 (2008) 748-766
27. Miller L., and Dumas P. Chemical imaging of biological tissue with synchrotron infrared light. Biochim Biophys Acta 1758 (2006) 846-857
28. Mitewa M., Enchev V., and Bakalova T. Spectroscopic and quantum chemical study of the structure of a new paramagnetic dimeric palladium(II, III) complex with creatine. J Mol Struct 609 (2002) 61-65
29. Ohtsuki S., Tachikawa M., Takanaga H., Shimizu H., Watanabe M., Hosoya K., and Terasaki T. The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the brain. J Cereb Blood Flow Metab 22 (2002) 1327-1335
30. Podstawka E., Swiatlowska M., Borowiec E., and Proniewicz L.M. Food additives characterization by infrared, Raman, and surface-enhanced Raman spectroscopies. J Raman Spectrosc 38 3 (2007) 356-363
31. Rak M. Synchrotron infrared microspectroscopy of biological tissues: brain tissue from TgCRND8 Alzheimer's disease mice and developing scar tissue in rats. PhD. Sc.: Thesis (2007), University of Manitoba, Winnipeg, Canada
32. Rak M., Del Bigio M.R., Mai S., Westaway D., and Gough K. Dense-core and diffuse Abeta plaques in TgCRND8 mice studied with synchrotron FTIR microspectroscopy. Biopolymers 87 (2007) 207-211
33. Roberts B.R., Tainer J.A., Getzoff E.D., Malencik D.A., Anderson S.R., Bomben V.C., Meyers K.R., Karplus P.A., and Beckman J.S. Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. J Mol Biol 373 4 (2007) 877-890
34. Rosenfeld J., King R.M., Jackson C.E., Bedlack R.S., Barohn R.J., Dick A., Phillips L.H., Chapin J., Gelinas D.F., and Lou J.S. Creatine monohydrate in ALS: effects on strength, fatigue, respiratory status and ALSFRS. Amyotroph Lateral Scler 9 5 (2008) 266-272
35. Rowland L.P. Diagnosis of amyotrophic lateral sclerosis. J Neurol Sci 160 Suppl (1998) S6-S24
36. Sandyk R. Serotonergic mechanisms in amyotrophic lateral sclerosis. Int J Neurosci 116 7 (2006) 775-826
37. Schlattner U., Tokarska-Schlattner M., and Wallimann T. Mitochondrial creatine kinase in human health and disease. Biochim Biophys Acta 1762 (2006) 164-180
38. Shaw P.J. Molecular and cellular pathways of neurodegeneration in motor neurone disease. J Neurol Neurosurg Psychiatry 76 8 (2005) 1046-1057
39. Shefner J.M., Cudkowicz M.E., Schoenfeld D., Conrad T., Taft J., Chilton M., Urbinelli L., Qureshi M., Zhang H., Pestronk A., Caress J., Donofrio P., Sorenson E., Bradley W., Lomen-Hoerth C., Pioro E., Rezania K., Ross M., Pascuzzi R., Heiman-Patterson T., Tandan R., Mitsumoto H., Rothstein J., Smith-Palmer T., MacDonald D., and Burke D. A clinical trial of creatine in ALS. Neurology 63 9 (2004) 1656-1661
40. Spreux-Varoquaux O., Bensimon G., Lacomblez L., Salachas F., Pradat P.F., Le Forestier N., Marouan A., Dib M., and Meininger V. Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients. J Neurol Sci 193 2 (2002) 73-78
41. Strong M.J., Volkening K., Hammond R., Yang W., Strong W., Leystra-Lantz C., and Shoesmith C. TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein. Mol Cell Neurosci 35 2 (2007) 320-327
42. Strong M.J., Kesavapany S., and Pant H.C. The pathobiology of amyotrophic lateral sclerosis: a proteinopathy?. J Neuropathol Exp Neurol 64 8 (2005) 649-664
43. Strong M.J., Yang W., Strong W.L., Leystra-Lantz C., Jaffe H., and Pant H.C. Tau protein hyperphosphorylation in sporadic ALS with cognitive impairment. Neurology 66 11 (2006) 1770-1771
44. Swash M., Scholz C., Vowks G., and Ingram D. Selective and asymmetrical vulnerability of corticospinal and spinocerebellar tracts in motor neuron disease. J Neurol Neurosurg Psychiatry 51 (1988) 785-789
45. Szczerbowska-Boruchowska M., Lankosz M., Ostachowicz J., Adamek D., Krygowska-Wajs A., Tomik B., Szczudlik A., Simionovici A., and Bohic S. Topographic and quantitative microanalysis of human central nervous system tissue using synchrotron radiation. X-Ray Spectrom 33 (2004) 3-11
46. Szczerbowska-Boruchowska M. X-ray fluorescence spectrometry, an analytical tool in neurochemical research. X-Ray Spectrom 37 (2008) 21-31
47. Tarnopolsky M.A., and Safdar A. The potential benefits of creatine and conjugated linoleic acid as adjuncts to resistance training in older adults. Appl Physiol Nutr Metab 33 1 (2008) 213-227
48. Thomzig A., Spassov S., Friedrich M., Naumann D., and Beekes M. Discriminating scrapie and bovine spongiform encephalopathy isolates by infrared spectroscopy of pathological prion protein. JBC 279 32 (2004) 33847-33854
49. Tomik B., Chwiej J., Szczerbowska-Boruchowska M., Lankosz M., Wójcik S., Adamek D., Falkenberg G., Bohic S., Simionovici A., Stegowski Z., and Szczudlik A. Implementation of X-ray fluorescence microscopy for investigation of elemental abnormalities in amyotrophic lateral sclerosis. Neurochem Res 4 (2006) 321-331
50. Trushina E., and McMurray C.T. Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases. Neuroscience 145 (2007) 1233-1248
51. Watzel B., Speer O., Zanolla E., Eriksson O., Bernardi P., and Wallimann T. Novel mitochondrial creatine transport activity: implications for intracellular creatine compartments and bioenergetics. J Biol Chem 277 (2002) 37503-37511
52. Wilson C.M., Grace G.M., Munoz D.G., He B.P., and Strong M.J. Cognitive impairment in sporadic ALS: a pathologic continuum underlying a multisystem disorder. Neurology 57 4 (2001) 651-657
53. Wood J.D., Beaujeux T.P., and Shaw P.J. Protein aggregation in motor neurone disorders. Neuropathol Appl Neurobiol 29 6 (2003) 529-545
54. Xiao S., Tjostheim S., Sanelli T., McLean J.R., Horne P., Fan Y., Ravits J., Strong M.J., and Robertson J. An aggregate-inducing peripherin isoform generated through intron retention is upregulated in amyotrophic lateral sclerosis and associated with disease pathology. J Neurosci 28 8 (2008) 1833-1840
55. Yang W., Sopper M.M., Leystra-Lantz C., and Strong M.J. Microtubule-associated tau protein positive neuronal and glial inclusions in ALS. Neurology 61 (2003) 1766-1773
56. Zecca L., Zucca F.A., Wilms H., and Sulzer D. Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics. Trends Neurosci 26 (2003) 578-580