메뉴 건너뛰기




Volumn 153, Issue 2, 2010, Pages 387-396

The Tryptophan Hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: A multi-centre case-control study and meta-analysis

Author keywords

Case control association study; Metaanalysis; Schizophrenia; Suicidal behavior; Tryptophan hydroxylase 1 gene (TPH1)

Indexed keywords

ADULT; ARTICLE; ASIAN; CASE CONTROL STUDY; CAUCASIAN; CLINICAL TRIAL; FEMALE; GENE; GENE FREQUENCY; GENE LOCUS; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; INSURANCE; INTRON; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; META ANALYSIS; PRIORITY JOURNAL; SCANDINAVIA; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; SUICIDAL BEHAVIOR; SUICIDE ATTEMPT; SYSTEMATIC REVIEW; TRYPTOPHAN HYDROXYLASE 1 GENE;

EID: 77349098812     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30991     Document Type: Article
Times cited : (49)

References (67)
  • 1
    • 33847345013 scopus 로고    scopus 로고
    • Alterations of serotonin transmission in schizophrenia
    • Abi-Dargham A. 2007. Alterations of serotonin transmission in schizophrenia. Int Rev Neurobiol 78:133-164.
    • (2007) Int Rev Neurobiol , vol.78 , pp. 133-164
    • Abi-Dargham, A.1
  • 2
    • 0028671866 scopus 로고
    • Electrophysiological studies on the actions of hallucinogenic drugs at 5-HT2 receptors in rat brain
    • Aghajanian GK. 1994. Electrophysiological studies on the actions of hallucinogenic drugs at 5-HT2 receptors in rat brain. NIDA Res Monogr 146:183-202.
    • (1994) NIDA Res Monogr , vol.146 , pp. 183-202
    • Aghajanian, G.K.1
  • 5
    • 0029134538 scopus 로고
    • Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims
    • Arango V, Underwood MD, Gubbi AV, Mann JJ. 1995. Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims. Brain Res 688:121-133.
    • (1995) Brain Res , vol.688 , pp. 121-133
    • Arango, V.1    Underwood, M.D.2    Gubbi, A.V.3    Mann, J.J.4
  • 6
    • 0031590779 scopus 로고    scopus 로고
    • Åsberg M. 1997. Neurotransmitters and suicidal behavior. The evidence from cerebrospinal fluid studies. Ann NY Acad Sci 836:158-181. Barrett JC, Fry B, Maller J, Daly MJ. 2005. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265. Beautrais AL, Joyce PR, Mulder RT, FergussonDM,Deavoll BJ, Nightingale SK. 1996. Prevalence and comorbidity of mental disorders in persons making serious suicide attempts: A case-control study. Am J Psychiatry 153:1009-1014.
    • Åsberg M. 1997. Neurotransmitters and suicidal behavior. The evidence from cerebrospinal fluid studies. Ann NY Acad Sci 836:158-181. Barrett JC, Fry B, Maller J, Daly MJ. 2005. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21:263-265. Beautrais AL, Joyce PR, Mulder RT, FergussonDM,Deavoll BJ, Nightingale SK. 1996. Prevalence and comorbidity of mental disorders in persons making serious suicide attempts: A case-control study. Am J Psychiatry 153:1009-1014.
  • 8
    • 0347993742 scopus 로고    scopus 로고
    • Association between the TPH gene A218C polymorphism and suicidal behavior: A meta-analysis.Am
    • Bellivier F, Chaste P, Malafosse A. 2004. Association between the TPH gene A218C polymorphism and suicidal behavior: A meta-analysis.Am J Med Genet Part B 124B:87-91.
    • (2004) J Med Genet , vol.124 B , Issue.PART B , pp. 87-91
    • Bellivier, F.1    Chaste, P.2    Malafosse, A.3
  • 9
    • 0030273870 scopus 로고    scopus 로고
    • 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia
    • Burnet PW, Eastwood SL, Harrison PJ. 1996. 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia. Neuropsychopharmacology 15:442-455.
    • (1996) Neuropsychopharmacology , vol.15 , pp. 442-455
    • Burnet, P.W.1    Eastwood, S.L.2    Harrison, P.J.3
  • 11
    • 0037043826 scopus 로고    scopus 로고
    • Aromatic amino acid hydroxylase genes and schizophrenia
    • Chao HM, Richardson MA. 2002. Aromatic amino acid hydroxylase genes and schizophrenia. Am J Med Genet 114:626-630.
    • (2002) Am J Med Genet , vol.114 , pp. 626-630
    • Chao, H.M.1    Richardson, M.A.2
  • 12
    • 0037628112 scopus 로고    scopus 로고
    • Gene-environment interaction in psychiatric disorders as indicated by season of birth variations in tryptophan hydroxylase (TPH), serotonin transporter (5-HTTLPR) and dopamine receptor (DRD4) gene polymorphisms
    • Chotai J, Serretti A, Lattuada E, Lorenzi C, Lilli R. 2003. Gene-environment interaction in psychiatric disorders as indicated by season of birth variations in tryptophan hydroxylase (TPH), serotonin transporter (5-HTTLPR) and dopamine receptor (DRD4) gene polymorphisms. Psychiatry Res 119:99-111.
    • (2003) Psychiatry Res , vol.119 , pp. 99-111
    • Chotai, J.1    Serretti, A.2    Lattuada, E.3    Lorenzi, C.4    Lilli, R.5
  • 14
    • 13244269954 scopus 로고    scopus 로고
    • Suicidal behavior: Relationship between phenotype and serotonergic genotype
    • Courtet P, Jollant F, Castelnau D, Buresi C, Malafosse A. 2005. Suicidal behavior: Relationship between phenotype and serotonergic genotype. Am J Med Genet Part C 133C:25-33.
    • (2005) Am J Med Genet , vol.133 C , Issue.PART C , pp. 25-33
    • Courtet, P.1    Jollant, F.2    Castelnau, D.3    Buresi, C.4    Malafosse, A.5
  • 15
    • 0032586747 scopus 로고    scopus 로고
    • Changes in serotonin2A and GABA(A) receptors in schizophrenia: Studies on the human dorsolateral prefrontal cortex
    • Dean B, Hussain T, Hayes W, Scarr E, Kitsoulis S, Hill C, Opeskin K, Copolov DL. 1999. Changes in serotonin2A and GABA(A) receptors in schizophrenia: Studies on the human dorsolateral prefrontal cortex. J Neurochem 72:1593-1599.
    • (1999) J Neurochem , vol.72 , pp. 1593-1599
    • Dean, B.1    Hussain, T.2    Hayes, W.3    Scarr, E.4    Kitsoulis, S.5    Hill, C.6    Opeskin, K.7    Copolov, D.L.8
  • 17
    • 0041857847 scopus 로고    scopus 로고
    • Pedigree disequilibrium tests for multilocus haplotypes
    • Dudbridge F. 2003. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 25:115-121.
    • (2003) Genet Epidemiol , vol.25 , pp. 115-121
    • Dudbridge, F.1
  • 18
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • Dudbridge F. 2008. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered 66:87-98.
    • (2008) Hum Hered , vol.66 , pp. 87-98
    • Dudbridge, F.1
  • 19
    • 0030922816 scopus 로고    scopus 로고
    • Bias in metaanalysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C. 1997. Bias in metaanalysis detected by a simple, graphical test. Br Med J 315:629-634.
    • (1997) Br Med J , vol.315 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 22
    • 0032496310 scopus 로고    scopus 로고
    • No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behavior in major affective disorder
    • Furlong RA, Ho L, Rubinsztein JS, Walsh C, Paykel ES, Rubinsztein DC. 1998. No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behavior in major affective disorder. Am J Med Genet 81:245-247.
    • (1998) Am J Med Genet , vol.81 , pp. 245-247
    • Furlong, R.A.1    Ho, L.2    Rubinsztein, J.S.3    Walsh, C.4    Paykel, E.S.5    Rubinsztein, D.C.6
  • 26
    • 0034615045 scopus 로고    scopus 로고
    • Genetic associations with clinical characteristics in bipolar affective disorder and recurrent unipolar depressive disorder
    • Ho LW, Furlong RA, Rubinsztein JS, Walsh C, Paykel ES, Rubinsztein DC. 2000. Genetic associations with clinical characteristics in bipolar affective disorder and recurrent unipolar depressive disorder. Am J Med Genet 96:36-42.
    • (2000) Am J Med Genet , vol.96 , pp. 36-42
    • Ho, L.W.1    Furlong, R.A.2    Rubinsztein, J.S.3    Walsh, C.4    Paykel, E.S.5    Rubinsztein, D.C.6
  • 27
    • 0035871057 scopus 로고    scopus 로고
    • Association between tryptophan hydroxylase gene polymorphism (A218C) and schizophrenic disorders
    • Hong CJ, Shih JT, Ying CW. 2001. Association between tryptophan hydroxylase gene polymorphism (A218C) and schizophrenic disorders. Schizophr Res 49:59-63.
    • (2001) Schizophr Res , vol.49 , pp. 59-63
    • Hong, C.J.1    Shih, J.T.2    Ying, C.W.3
  • 31
    • 24944435054 scopus 로고    scopus 로고
    • Tryptophan hydroxylase gene 1 polymorphisms are not associated with suicide attempts in alcohol-dependent individuals
    • Koller G, Engel RR, Preuss UW, Karakesisoglou A, Zill P, Bondy B, Soyka M. 2005. Tryptophan hydroxylase gene 1 polymorphisms are not associated with suicide attempts in alcohol-dependent individuals. Addict Biol 10:269-273.
    • (2005) Addict Biol , vol.10 , pp. 269-273
    • Koller, G.1    Engel, R.R.2    Preuss, U.W.3    Karakesisoglou, A.4    Zill, P.5    Bondy, B.6    Soyka, M.7
  • 32
    • 0032895446 scopus 로고    scopus 로고
    • No evidence for an association of polymorphisms of the tryptophan hydroxylase gene with affective disorders or attempted suicide among Japanese patients
    • Kunugi H, Ishida S, Kato T, Sakai T, Tatsumi M, Hirose T, Nanko S. 1999. No evidence for an association of polymorphisms of the tryptophan hydroxylase gene with affective disorders or attempted suicide among Japanese patients. Am J Psychiatry 156:774-776.
    • (1999) Am J Psychiatry , vol.156 , pp. 774-776
    • Kunugi, H.1    Ishida, S.2    Kato, T.3    Sakai, T.4    Tatsumi, M.5    Hirose, T.6    Nanko, S.7
  • 33
    • 33644992483 scopus 로고    scopus 로고
    • Further clarification of the contribution of the tryptophan hydroxylase (TPH) gene to suicidal behavior using systematic allelic and genotypic meta-analyses
    • HeL
    • Li D, HeL. 2006. Further clarification of the contribution of the tryptophan hydroxylase (TPH) gene to suicidal behavior using systematic allelic and genotypic meta-analyses. Hum Genet 119:233-240.
    • (2006) Hum Genet , vol.119 , pp. 233-240
    • Li, D.1
  • 34
    • 58149464318 scopus 로고    scopus 로고
    • Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study
    • Lichtenstein P, Yip BH, Björk C, Pawitan Y, Cannon TD, Sullivan PF, Hultman CM. 2009. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study. Lancet 373:234-239.
    • (2009) Lancet , vol.373 , pp. 234-239
    • Lichtenstein, P.1    Yip, B.H.2    Björk, C.3    Pawitan, Y.4    Cannon, T.D.5    Sullivan, P.F.6    Hultman, C.M.7
  • 36
    • 33746890199 scopus 로고    scopus 로고
    • Association ofTPH1 with suicidal behaviour and psychiatric disorders in the Chinese population
    • Liu X, Li H, Qin W, He G, Li D, Shen Y, Shen J, Gu N, Feng G, He L. 2006. Association ofTPH1 with suicidal behaviour and psychiatric disorders in the Chinese population. J Med Genet 43:e4.
    • (2006) J Med Genet , vol.43
    • Liu, X.1    Li, H.2    Qin, W.3    He, G.4    Li, D.5    Shen, Y.6    Shen, J.7    Gu, N.8    Feng, G.9    He, L.10
  • 37
    • 0031040710 scopus 로고    scopus 로고
    • Cerebrospinal fluid amines and higher lethality suicide attempts in depressed inpatients
    • Mann JJ, Malone KM. 1997. Cerebrospinal fluid amines and higher lethality suicide attempts in depressed inpatients. Biol Psychiatry 41:162-171.
    • (1997) Biol Psychiatry , vol.41 , pp. 162-171
    • Mann, J.J.1    Malone, K.M.2
  • 38
    • 0030770598 scopus 로고    scopus 로고
    • Possible association of a polymorphism of the tryptophan hydroxylase gene with suicidal behavior
    • Mann JJ, Malone KM, Nielsen DA, Goldman D, Erdos J, Gelernter J. 1997. Possible association of a polymorphism of the tryptophan hydroxylase gene with suicidal behavior. Am J Psychiatry 154:1451-1453.
    • (1997) Am J Psychiatry , vol.154 , pp. 1451-1453
    • Mann, J.J.1    Malone, K.M.2    Nielsen, D.A.3    Goldman, D.4    Erdos, J.5    Gelernter, J.6
  • 40
    • 17444423355 scopus 로고    scopus 로고
    • 5-HT2A and muscarinic receptors in schizophrenia: A postmortem study
    • Matsumoto I, Inoue Y, Iwazaki T, Pavey G, Dean B. 2005. 5-HT2A and muscarinic receptors in schizophrenia: A postmortem study. Neurosci Lett 379:164-168.
    • (2005) Neurosci Lett , vol.379 , pp. 164-168
    • Matsumoto, I.1    Inoue, Y.2    Iwazaki, T.3    Pavey, G.4    Dean, B.5
  • 42
    • 0028117344 scopus 로고
    • Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism
    • Nielsen DA, Goldman D, Virkkunen M, Tokola R, Rawlings R, Linnoila M. 1994. Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism. Arch Gen Psychiatry 51:34-38.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 34-38
    • Nielsen, D.A.1    Goldman, D.2    Virkkunen, M.3    Tokola, R.4    Rawlings, R.5    Linnoila, M.6
  • 44
    • 0033940142 scopus 로고    scopus 로고
    • TPH gene may be associated with suicidal behavior, but not with schizophrenia in the Korean population
    • Paik I, Toh K, Kim J, Lee C. 2000.TPH gene may be associated with suicidal behavior, but not with schizophrenia in the Korean population. Human Heredity 50:365-369.
    • (2000) Human Heredity , vol.50 , pp. 365-369
    • Paik, I.1    Toh, K.2    Kim, J.3    Lee, C.4
  • 45
    • 14844364096 scopus 로고    scopus 로고
    • The lifetime risk of suicide in schizophrenia: A reexamination
    • Palmer BA, Pankratz VS, Bostwick JM. 2005. The lifetime risk of suicide in schizophrenia: A reexamination. Arch Gen Psychiatry 62:247-253.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 247-253
    • Palmer, B.A.1    Pankratz, V.S.2    Bostwick, J.M.3
  • 46
    • 34548629380 scopus 로고    scopus 로고
    • Genetic variation and shared biological susceptibility underlying comorbidity in neuropsychiatry
    • Palomo T, Kostrzewa RM, Beninger RJ, Archer T. 2007. Genetic variation and shared biological susceptibility underlying comorbidity in neuropsychiatry. Neurotoxicity Res 12:29-42.
    • (2007) Neurotoxicity Res , vol.12 , pp. 29-42
    • Palomo, T.1    Kostrzewa, R.M.2    Beninger, R.J.3    Archer, T.4
  • 47
    • 0034668859 scopus 로고    scopus 로고
    • Developmental regulation of tryptophan hydroxylase messenger RNA expression and enzyme activity in the raphe and its target fields
    • Rind HB, Russo AF, Whittemore SR. 2000. Developmental regulation of tryptophan hydroxylase messenger RNA expression and enzyme activity in the raphe and its target fields. Neuroscience 101:665-677.
    • (2000) Neuroscience , vol.101 , pp. 665-677
    • Rind, H.B.1    Russo, A.F.2    Whittemore, S.R.3
  • 48
    • 0142042980 scopus 로고    scopus 로고
    • Genetic variations in tryptophan hydroxylase in suicidal behavior: Analysis and meta-analysis
    • Rujescu D, Giegling I, Sato T, Hartmann AM, Moller HJ. 2003. Genetic variations in tryptophan hydroxylase in suicidal behavior: Analysis and meta-analysis. Biol Psychiatry 54:465-473.
    • (2003) Biol Psychiatry , vol.54 , pp. 465-473
    • Rujescu, D.1    Giegling, I.2    Sato, T.3    Hartmann, A.M.4    Moller, H.J.5
  • 49
    • 33646542677 scopus 로고    scopus 로고
    • Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies
    • Sakowski SA, Geddes TJ, Thomas DM, Levi E, Hatfield JS, Kuhn DM. 2006. Differential tissue distribution of tryptophan hydroxylase isoforms 1 and 2 as revealed with monospecific antibodies. Brain Res 1085:11-18.
    • (2006) Brain Res , vol.1085 , pp. 11-18
    • Sakowski, S.A.1    Geddes, T.J.2    Thomas, D.M.3    Levi, E.4    Hatfield, J.S.5    Kuhn, D.M.6
  • 53
    • 0036706019 scopus 로고    scopus 로고
    • Candidate gene polymorphisms among North Indians and their association with schizophrenia in a case-control study
    • Semwal P, Prasad S, Varma PG, Bhagwat AM, Deshpande SN, Thelma BK. 2002. Candidate gene polymorphisms among North Indians and their association with schizophrenia in a case-control study. J Genet 81:65-71.
    • (2002) J Genet , vol.81 , pp. 65-71
    • Semwal, P.1    Prasad, S.2    Varma, P.G.3    Bhagwat, A.M.4    Deshpande, S.N.5    Thelma, B.K.6
  • 56
    • 0034457919 scopus 로고    scopus 로고
    • Polymorphisms of tryptophan hydroxylase gene and the symptomatology of schizophrenia: An association study
    • Shinkai T, Ohmori O, Suzuki T, Kojima H, Hori H, Terao T, Nakamura J. 2000. Polymorphisms of tryptophan hydroxylase gene and the symptomatology of schizophrenia: An association study. Psychiatr Genet 10:165-171.
    • (2000) Psychiatr Genet , vol.10 , pp. 165-171
    • Shinkai, T.1    Ohmori, O.2    Suzuki, T.3    Kojima, H.4    Hori, H.5    Terao, T.6    Nakamura, J.7
  • 59
    • 46449113977 scopus 로고    scopus 로고
    • Tandon R, Keshavan MS, Nasrallah HA. 2008. Schizophrenia, Just the Facts What we know in 2008. 2. Epidemiology and etiology. Schizophr Res 102:1-18. Tsai SJ, Hong CJ, Wang YC. 1999. Tryptophan hydroxylase gene polymorphism (A218C) and suicidal behaviors. Neuroreport 10:3773-3775.
    • Tandon R, Keshavan MS, Nasrallah HA. 2008. Schizophrenia, "Just the Facts" What we know in 2008. 2. Epidemiology and etiology. Schizophr Res 102:1-18. Tsai SJ, Hong CJ, Wang YC. 1999. Tryptophan hydroxylase gene polymorphism (A218C) and suicidal behaviors. Neuroreport 10:3773-3775.
  • 60
    • 33646942132 scopus 로고    scopus 로고
    • Investigation of A218C tryptophan hydroxylase polymorphism: Association with familial suicide behavior and proband's suicide attempt characteristics
    • Viana MM, De Marco LA, Boson WL, Romano-Silva MA, Correa H. 2006. Investigation of A218C tryptophan hydroxylase polymorphism: Association with familial suicide behavior and proband's suicide attempt characteristics. Genes Brain Behav 5:340-345.
    • (2006) Genes Brain Behav , vol.5 , pp. 340-345
    • Viana, M.M.1    De Marco, L.A.2    Boson, W.L.3    Romano-Silva, M.A.4    Correa, H.5
  • 61
    • 34848925487 scopus 로고    scopus 로고
    • The tryptophan hydroxylase 1 (TPH1) gene and risk of schizophrenia: A moderatescale case-control study and meta-analysis
    • Watanabe Y, Nunokawa A, Kaneko N, Someya T. 2007. The tryptophan hydroxylase 1 (TPH1) gene and risk of schizophrenia: A moderatescale case-control study and meta-analysis. Neurosci Res 59:322-326.
    • (2007) Neurosci Res , vol.59 , pp. 322-326
    • Watanabe, Y.1    Nunokawa, A.2    Kaneko, N.3    Someya, T.4
  • 62
    • 24044550689 scopus 로고    scopus 로고
    • PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data
    • Wigginton JE, Abecasis GR. 2005. PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics 21:3445-3447.
    • (2005) Bioinformatics , vol.21 , pp. 3445-3447
    • Wigginton, J.E.1    Abecasis, G.R.2
  • 63
    • 61449143563 scopus 로고    scopus 로고
    • The tryptophan hydroxylase-1 A218C polymorphism is associated with diagnosis, but not suicidal behavior, in borderline personality disorder
    • Wilson ST, Stanley B, Brent DA, Oquendo MA, Huang YY, Mann JJ. 2009. The tryptophan hydroxylase-1 A218C polymorphism is associated with diagnosis, but not suicidal behavior, in borderline personality disorder. Am J Med Genet B Neuropsychiatr Genet 150B(2):202-208.
    • (2009) Am J Med Genet B Neuropsychiatr Genet , vol.150 B , Issue.2 , pp. 202-208
    • Wilson, S.T.1    Stanley, B.2    Brent, D.A.3    Oquendo, M.A.4    Huang, Y.Y.5    Mann, J.J.6
  • 64
    • 40849126808 scopus 로고    scopus 로고
    • Covariance component models for multivariate binary traits in family data analysis
    • Yip BH, Björk C, Lichtenstein P, Hultman CM, Pawitan Y. 2008. Covariance component models for multivariate binary traits in family data analysis. Stat Med 27:1086-1105.
    • (2008) Stat Med , vol.27 , pp. 1086-1105
    • Yip, B.H.1    Björk, C.2    Lichtenstein, P.3    Hultman, C.M.4    Pawitan, Y.5
  • 67
    • 33750725388 scopus 로고    scopus 로고
    • Analysis of tryptophan hydroxylase I and II mRNA expression in the human brain: A post-mortem study
    • Zill P, Buttner A, Eisenmenger W, Moller HJ, Ackenheil M, Bondy B. 2007. Analysis of tryptophan hydroxylase I and II mRNA expression in the human brain: A post-mortem study. J Psychiatr Res 41:168-173.
    • (2007) J Psychiatr Res , vol.41 , pp. 168-173
    • Zill, P.1    Buttner, A.2    Eisenmenger, W.3    Moller, H.J.4    Ackenheil, M.5    Bondy, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.