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Volumn 78, Issue 3, 2010, Pages 1314-1325

Anaplasma marginale type IV secretion system proteins VirB2, VirB7, VirB11, and VirD4 are immunogenic components of a protective bacterial membrane vaccine

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASMOSIS VACCINE; BACTERIAL PROTEIN; PROTEIN VIRB11; PROTEIN VIRB2; PROTEIN VIRB7; PROTEIN VIRD4; UNCLASSIFIED DRUG;

EID: 77349097993     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01207-09     Document Type: Article
Times cited : (37)

References (75)
  • 1
    • 18944375014 scopus 로고    scopus 로고
    • 4+ T lymphocyte responses specific for Anaplasma marginale major surface protein-2 (MSP2) in MSP2 vaccinates following challenge with live A. marginale
    • 4+ T lymphocyte responses specific for Anaplasma marginale major surface protein-2 (MSP2) in MSP2 vaccinates following challenge with live A. marginale. J. Immunol. 174:6702-6715.
    • (2005) J. Immunol , vol.174 , pp. 6702-6715
    • Abbott, J.R.1    Palmer, G.H.2    Kegerreis, K.A.3    Hetrick, P.F.4    Howard, C.J.5    Hope, J.C.6    Brown, W.C.7
  • 2
    • 0029840358 scopus 로고    scopus 로고
    • Agrobacterium tumefaciens VirB7 and VirB9 form a disulfide-linked protein complex
    • Anderson, L. B., A. V. Hertzel, and A. Das. 1996. Agrobacterium tumefaciens VirB7 and VirB9 form a disulfide-linked protein complex. Proc. Natl. Acad. Sci. U. S. A. 93:8889-8894.
    • (1996) Proc. Natl. Acad. Sci. U. S. A , vol.93 , pp. 8889-8894
    • Anderson, L.B.1    Hertzel, A.V.2    Das, A.3
  • 3
    • 33748667977 scopus 로고    scopus 로고
    • Characterization of the pilin ortholog of the Helicobacter pylori type IV cag pathogenicity apparatus, a surface-associated protein expressed during infection
    • Andrzejewska, J., S. K. Lee, P. Olbermann, N. Lotzing, E. Katzowitsch, B. Linz, M. Achtman, C. I. Kado, S. Suerbaum, and C. Josenhans. 2006. Characterization of the pilin ortholog of the Helicobacter pylori type IV cag pathogenicity apparatus, a surface-associated protein expressed during infection. J. Bacteriol. 188:5865-5877.
    • (2006) J. Bacteriol , vol.188 , pp. 5865-5877
    • Andrzejewska, J.1    Lee, S.K.2    Olbermann, P.3    Lotzing, N.4    Katzowitsch, E.5    Linz, B.6    Achtman, M.7    Kado, C.I.8    Suerbaum, S.9    Josenhans, C.10
  • 7
    • 0028243807 scopus 로고
    • Genetic complementation analysis of the Agrobacterium tumefaciens virB operon: VirB2 through virB11 are essential virulence genes
    • Berger, B. R., and P. J. Christie. 1994. Genetic complementation analysis of the Agrobacterium tumefaciens virB operon: virB2 through virB11 are essential virulence genes. J. Bacteriol. 176:3646-3660.
    • (1994) J. Bacteriol , vol.176 , pp. 3646-3660
    • Berger, B.R.1    Christie, P.J.2
  • 9
    • 14144250820 scopus 로고    scopus 로고
    • Brayton, K. A., L. S. Kappmeyer, D. R. Herndon, M. J. Dark, D. L. Tibbals, G. H. Palmer, T. C. McGuire, and D. P. Knowles, Jr. 2005. Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proc. Natl. Acad. Sci. U. S. A. 102:844-849.
    • Brayton, K. A., L. S. Kappmeyer, D. R. Herndon, M. J. Dark, D. L. Tibbals, G. H. Palmer, T. C. McGuire, and D. P. Knowles, Jr. 2005. Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proc. Natl. Acad. Sci. U. S. A. 102:844-849.
  • 10
    • 0035957321 scopus 로고    scopus 로고
    • Efficient use of a small genome to generate antigenic diversity in tick-borne ehrlichial pathogens
    • Brayton, K. A., D. P. Knowles, T. C. McGuire, and G. H. Palmer. 2001. Efficient use of a small genome to generate antigenic diversity in tick-borne ehrlichial pathogens. Proc. Natl. Acad. Sci. U. S. A. 98:4130-4135.
    • (2001) Proc. Natl. Acad. Sci. U. S. A , vol.98 , pp. 4130-4135
    • Brayton, K.A.1    Knowles, D.P.2    McGuire, T.C.3    Palmer, G.H.4
  • 11
    • 0242349607 scopus 로고    scopus 로고
    • Simultaneous variation of the immunodominant outer membrane proteins, MSP2 and MSP3, during Anaplasma marginale persistence in vivo
    • Brayton, K. A., P. F. Meeus, A. F. Barbet, and G. H. Palmer. 2003. Simultaneous variation of the immunodominant outer membrane proteins, MSP2 and MSP3, during Anaplasma marginale persistence in vivo. Infect. Immun. 71:6627-6632.
    • (2003) Infect. Immun , vol.71 , pp. 6627-6632
    • Brayton, K.A.1    Meeus, P.F.2    Barbet, A.F.3    Palmer, G.H.4
  • 12
    • 33646471882 scopus 로고    scopus 로고
    • Genomic and proteomic approaches to vaccine candidate identification for Anaplasma marginale
    • Brayton, K. A., G. H. Palmer, and W. C. Brown. 2006. Genomic and proteomic approaches to vaccine candidate identification for Anaplasma marginale. Expert Rev. Vaccines 5:95-101.
    • (2006) Expert Rev. Vaccines , vol.5 , pp. 95-101
    • Brayton, K.A.1    Palmer, G.H.2    Brown, W.C.3
  • 13
    • 0032425064 scopus 로고    scopus 로고
    • 4+ T-lymphocyte and IgG2 responses in calves immunized with Anaplasma marginale outer membranes and protected against homologous challenge
    • 4+ T-lymphocyte and IgG2 responses in calves immunized with Anaplasma marginale outer membranes and protected against homologous challenge. Infect. Immun. 66:5406-5413.
    • (1998) Infect. Immun , vol.66 , pp. 5406-5413
    • Brown, W.C.1    Shkap, V.2    Zhu, D.3    McGuire, T.C.4    Tuo, W.5    McElwain, T.F.6    Palmer, G.H.7
  • 14
    • 1842456892 scopus 로고    scopus 로고
    • The versatile bacterial type IV secretion systems
    • Cascales, E., and P. J. Christie. 2003. The versatile bacterial type IV secretion systems. Nat. Rev. Microbiol. 1:137-149.
    • (2003) Nat. Rev. Microbiol , vol.1 , pp. 137-149
    • Cascales, E.1    Christie, P.J.2
  • 15
    • 0041920932 scopus 로고    scopus 로고
    • Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum
    • Celli, J., C. de Chastellier, D. M. Franchini, J. Pizzaro-Cerda, E. Moreno, and J. P. Gorvel. 2003. Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum. J. Exp. Med. 198:545-556.
    • (2003) J. Exp. Med , vol.198 , pp. 545-556
    • Celli, J.1    de Chastellier, C.2    Franchini, D.M.3    Pizzaro-Cerda, J.4    Moreno, E.5    Gorvel, J.P.6
  • 17
    • 20044391604 scopus 로고    scopus 로고
    • Collins, N. E., J. Liebenberg, E. P. de Villiers, K. A. Brayton, E. A. Pretorius, F. E. Faber, H. van Heerden, A. Josemans, M. van Kleef, H. C. Steyn, M. F. van Strijp, E. Zweygarth, F. Jongejan, J. C. Maillard, D. Berthier, M. Botha, F. Joubert, C. H. Corton, N. R. Thomson, M. T. Allsopp, and B. A. Allsopp. 2005. The genome of the heartwater agent Ehrlichia ruminantium contains multiple tandem repeats of actively variable copy number. Proc. Natl. Acad. Sci. U. S. A. 102:838-843.
    • Collins, N. E., J. Liebenberg, E. P. de Villiers, K. A. Brayton, E. A. Pretorius, F. E. Faber, H. van Heerden, A. Josemans, M. van Kleef, H. C. Steyn, M. F. van Strijp, E. Zweygarth, F. Jongejan, J. C. Maillard, D. Berthier, M. Botha, F. Joubert, C. H. Corton, N. R. Thomson, M. T. Allsopp, and B. A. Allsopp. 2005. The genome of the heartwater agent Ehrlichia ruminantium contains multiple tandem repeats of actively variable copy number. Proc. Natl. Acad. Sci. U. S. A. 102:838-843.
  • 18
    • 0031014646 scopus 로고    scopus 로고
    • The VirB4 ATPase of Agrobacterium tumefaciens is a cytoplasmic membrane protein exposed at the periplasmic surface
    • Dang, T. A., and P. J. Christie. 1997. The VirB4 ATPase of Agrobacterium tumefaciens is a cytoplasmic membrane protein exposed at the periplasmic surface. J. Bacteriol. 179:453-462.
    • (1997) J. Bacteriol , vol.179 , pp. 453-462
    • Dang, T.A.1    Christie, P.J.2
  • 19
    • 46049115269 scopus 로고    scopus 로고
    • VirB3 to VirB6 and VirB8 to VirB11, but not VirB7, are essential for mediating persistence of Brucella in the reticuloendothelial system
    • den Hartigh, A. B., H. G. Rolan, M. F. de Jong, and R. M. Tsolis. 2008. VirB3 to VirB6 and VirB8 to VirB11, but not VirB7, are essential for mediating persistence of Brucella in the reticuloendothelial system. J. Bacteriol. 190: 4427-4436.
    • (2008) J. Bacteriol , vol.190 , pp. 4427-4436
    • den Hartigh, A.B.1    Rolan, H.G.2    de Jong, M.F.3    Tsolis, R.M.4
  • 20
    • 0035192367 scopus 로고    scopus 로고
    • Dumler, J. S., A. F. Barbet, C. P. Bekker, G. A. Dasch, G. H. Palmer, S. C. Ray, Y. Rikihisa, and F. R. Rurangirwa. 2001. Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and 'HGE agent' as subjective synonyms of Ehrlichia phagocytophila. Int. J. Syst. Evol. Microbiol. 51:2145-2165.
    • Dumler, J. S., A. F. Barbet, C. P. Bekker, G. A. Dasch, G. H. Palmer, S. C. Ray, Y. Rikihisa, and F. R. Rurangirwa. 2001. Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and 'HGE agent' as subjective synonyms of Ehrlichia phagocytophila. Int. J. Syst. Evol. Microbiol. 51:2145-2165.
  • 21
    • 33645760951 scopus 로고    scopus 로고
    • Dunning Hotopp, J. C., M. Lin, R. Madupu, J. Crabtree, S. V. Angiuoli, J. A. Eisen, R. Seshadri, Q. Ren, M. Wu, T. R. Utterback, S. Smith, M. Lewis, H. Khouri, C. Zhang, H. Niu, Q. Lin, N. Ohashi, N. Zhi, W. Nelson, L. M. Brinkac, R. J. Dodson, M. J. Rosovitz, J. Sundaram, S. C. Daugherty, T. Davidsen, A. S. Durkin, M. Gwinn, D. H. Haft, J. D. Selengut, S. A. Sullivan, N. Zafar, L. Zhou, F. Benahmed, H. Forberger, R. Halpin, S. Mulligan, J. Robinson, O. White, Y. Rikihisa, and H. Tettelin. 2006. Comparative genomics of emerging human ehrlichiosis agents. PLoS Genet. 2:e21.
    • Dunning Hotopp, J. C., M. Lin, R. Madupu, J. Crabtree, S. V. Angiuoli, J. A. Eisen, R. Seshadri, Q. Ren, M. Wu, T. R. Utterback, S. Smith, M. Lewis, H. Khouri, C. Zhang, H. Niu, Q. Lin, N. Ohashi, N. Zhi, W. Nelson, L. M. Brinkac, R. J. Dodson, M. J. Rosovitz, J. Sundaram, S. C. Daugherty, T. Davidsen, A. S. Durkin, M. Gwinn, D. H. Haft, J. D. Selengut, S. A. Sullivan, N. Zafar, L. Zhou, F. Benahmed, H. Forberger, R. Halpin, S. Mulligan, J. Robinson, O. White, Y. Rikihisa, and H. Tettelin. 2006. Comparative genomics of emerging human ehrlichiosis agents. PLoS Genet. 2:e21.
  • 22
  • 23
    • 0033529624 scopus 로고    scopus 로고
    • Conjugative pili of IncP plasmids, and the Ti plasmid T pilus are composed of cyclic subunits
    • Eisenbrandt, R., M. Kalkum, E. M. Lai, R. Lurz, C. I. Kado, and E. Lanka. 1999. Conjugative pili of IncP plasmids, and the Ti plasmid T pilus are composed of cyclic subunits. J. Biol. Chem. 274:22548-22555.
    • (1999) J. Biol. Chem , vol.274 , pp. 22548-22555
    • Eisenbrandt, R.1    Kalkum, M.2    Lai, E.M.3    Lurz, R.4    Kado, C.I.5    Lanka, E.6
  • 24
    • 0141446033 scopus 로고    scopus 로고
    • Sequence and expression analysis of virB9 of the type IV secretion system of Ehrlichia canis strains in ticks, dogs, and cultured cells
    • Felek, S., H. Huang, and Y. Rikihisa. 2003. Sequence and expression analysis of virB9 of the type IV secretion system of Ehrlichia canis strains in ticks, dogs, and cultured cells. Infect. Immun. 71:6063-6067.
    • (2003) Infect. Immun , vol.71 , pp. 6063-6067
    • Felek, S.1    Huang, H.2    Rikihisa, Y.3
  • 25
    • 0029941238 scopus 로고    scopus 로고
    • The Agrobacterium tumefaciens virB7 gene product, a proposed component of the T-complex transport apparatus, is a membraneassociated lipoprotein exposed at the periplasmic surface
    • Fernandez, D., T. A. Dang, G. M. Spudich, X. R. Zhou, B. R. Berger, and P. J. Christie. 1996. The Agrobacterium tumefaciens virB7 gene product, a proposed component of the T-complex transport apparatus, is a membraneassociated lipoprotein exposed at the periplasmic surface. J. Bacteriol. 178: 3156-3167.
    • (1996) J. Bacteriol , vol.178 , pp. 3156-3167
    • Fernandez, D.1    Dang, T.A.2    Spudich, G.M.3    Zhou, X.R.4    Berger, B.R.5    Christie, P.J.6
  • 26
    • 0029127480 scopus 로고
    • Interactions of VirB9, -10, and -11 with the membrane fraction of Agrobacterium tumefaciens: Solubility studies provide evidence for tight associations
    • Finberg, K. E., T. R. Muth, S. P. Young, J. B. Maken, S. M. Heitritter, A. N. Binns, and L. M. Banta. 1995. Interactions of VirB9, -10, and -11 with the membrane fraction of Agrobacterium tumefaciens: solubility studies provide evidence for tight associations. J. Bacteriol. 177:4881-4889.
    • (1995) J. Bacteriol , vol.177 , pp. 4881-4889
    • Finberg, K.E.1    Muth, T.R.2    Young, S.P.3    Maken, J.B.4    Heitritter, S.M.5    Binns, A.N.6    Banta, L.M.7
  • 27
    • 70349277187 scopus 로고    scopus 로고
    • The structural biology of type IV secretion systems
    • Fronzes, R., P. J. Christie, and G. Waksman. 2009. The structural biology of type IV secretion systems. Nat. Rev. Microbiol. 7:703-714.
    • (2009) Nat. Rev. Microbiol , vol.7 , pp. 703-714
    • Fronzes, R.1    Christie, P.J.2    Waksman, G.3
  • 29
    • 0032543212 scopus 로고    scopus 로고
    • Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides
    • Gallimore, A., T. Dumrese, H. Hengartner, R. M. Zinkernagel, and H. G. Rammensee. 1998. Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides. J. Exp. Med. 187:1647-1657.
    • (1998) J. Exp. Med , vol.187 , pp. 1647-1657
    • Gallimore, A.1    Dumrese, T.2    Hengartner, H.3    Zinkernagel, R.M.4    Rammensee, H.G.5
  • 30
    • 0031658742 scopus 로고    scopus 로고
    • A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells
    • Gallimore, A., J. Hombach, T. Dumrese, H. G. Rammensee, R. M. Zinkernagel, and H. Hengartner. 1998. A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells. Eur. J. Immunol. 28:3301-3311.
    • (1998) Eur. J. Immunol , vol.28 , pp. 3301-3311
    • Gallimore, A.1    Hombach, J.2    Dumrese, T.3    Rammensee, H.G.4    Zinkernagel, R.M.5    Hengartner, H.6
  • 31
    • 35648974248 scopus 로고    scopus 로고
    • Identification of novel surface proteins of Anaplasma phagocytophilum by affinity purification and proteomics
    • Ge, Y., and Y. Rikihisa. 2007. Identification of novel surface proteins of Anaplasma phagocytophilum by affinity purification and proteomics. J. Bacteriol. 189:7819-7828.
    • (2007) J. Bacteriol , vol.189 , pp. 7819-7828
    • Ge, Y.1    Rikihisa, Y.2
  • 33
    • 0034053027 scopus 로고    scopus 로고
    • TraG from RP4 and TraG and VirD4 from Ti plasmids confer relaxosome specificity to the conjugal transfer system of pTiC58
    • Hamilton, C. M., H. Lee, P. L. Li, D. M. Cook, K. R. Piper, S. B. von Bodman, E. Lanka, W. Ream, and S. K. Farrand. 2000. TraG from RP4 and TraG and VirD4 from Ti plasmids confer relaxosome specificity to the conjugal transfer system of pTiC58. J. Bacteriol. 182:1541-1548.
    • (2000) J. Bacteriol , vol.182 , pp. 1541-1548
    • Hamilton, C.M.1    Lee, H.2    Li, P.L.3    Cook, D.M.4    Piper, K.R.5    von Bodman, S.B.6    Lanka, E.7    Ream, W.8    Farrand, S.K.9
  • 35
    • 27744568778 scopus 로고    scopus 로고
    • The putative lytic transglycosylase VirB1 from Brucella suis interacts with the type IV secretion system core components VirB8, VirB9 and VirB11
    • Hoppner, C., A. Carle, D. Sivanesan, S. Hoeppner, and C. Baron. 2005. The putative lytic transglycosylase VirB1 from Brucella suis interacts with the type IV secretion system core components VirB8, VirB9 and VirB11. Microbiology 151:3469-3482.
    • (2005) Microbiology , vol.151 , pp. 3469-3482
    • Hoppner, C.1    Carle, A.2    Sivanesan, D.3    Hoeppner, S.4    Baron, C.5
  • 37
    • 0029835794 scopus 로고    scopus 로고
    • VirB2 is a processed pilin-like protein encoded by the Agrobacterium tumefaciens Ti plasmid
    • Jones, A. L., E. M. Lai, K. Shirasu, and C. I. Kado. 1996. VirB2 is a processed pilin-like protein encoded by the Agrobacterium tumefaciens Ti plasmid. J. Bacteriol. 178:5706-5711.
    • (1996) J. Bacteriol , vol.178 , pp. 5706-5711
    • Jones, A.L.1    Lai, E.M.2    Shirasu, K.3    Kado, C.I.4
  • 38
    • 0242349121 scopus 로고    scopus 로고
    • Protective efficacy of a fully recombinant plague vaccine in the guinea pig
    • Jones, S. M., K. F. Griffin, I. Hodgson, and E. D. Williamson. 2003. Protective efficacy of a fully recombinant plague vaccine in the guinea pig. Vaccine 21:3912-3918.
    • (2003) Vaccine , vol.21 , pp. 3912-3918
    • Jones, S.M.1    Griffin, K.F.2    Hodgson, I.3    Williamson, E.D.4
  • 39
    • 0037143720 scopus 로고    scopus 로고
    • Detergent extraction identifies different VirB protein subassemblies of the type IV secretion machinery in the membranes of Agrobacterium tumefaciens
    • Krall, L., U. Wiedemann, G. Unsin, S. Weiss, N. Domke, and C. Baron. 2002. Detergent extraction identifies different VirB protein subassemblies of the type IV secretion machinery in the membranes of Agrobacterium tumefaciens. Proc. Natl. Acad. Sci. U. S. A. 99:11405-11410.
    • (2002) Proc. Natl. Acad. Sci. U. S. A , vol.99 , pp. 11405-11410
    • Krall, L.1    Wiedemann, U.2    Unsin, G.3    Weiss, S.4    Domke, N.5    Baron, C.6
  • 40
    • 40449098575 scopus 로고    scopus 로고
    • Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies
    • Kutter, S., R. Buhrdorf, J. Haas, W. Schneider-Brachert, R. Haas, and W. Fischer. 2008. Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies. J. Bacteriol. 190:2161-2171.
    • (2008) J. Bacteriol , vol.190 , pp. 2161-2171
    • Kutter, S.1    Buhrdorf, R.2    Haas, J.3    Schneider-Brachert, W.4    Haas, R.5    Fischer, W.6
  • 41
    • 0036136240 scopus 로고    scopus 로고
    • Biogenesis of T pili in Agrobacterium tumefaciens requires precise VirB2 propilin cleavage and cyclization
    • Lai, E. M., R. Eisenbrandt, M. Kalkum, E. Lanka, and C. I. Kado. 2002. Biogenesis of T pili in Agrobacterium tumefaciens requires precise VirB2 propilin cleavage and cyclization. J. Bacteriol. 184:327-330.
    • (2002) J. Bacteriol , vol.184 , pp. 327-330
    • Lai, E.M.1    Eisenbrandt, R.2    Kalkum, M.3    Lanka, E.4    Kado, C.I.5
  • 42
    • 0029134827 scopus 로고
    • Active immunization with recombinant V antigen from Yersinia pestis protects mice against plague
    • Leary, S. E. C., E. D. Williamson, K. F. Griffin, P. Russell, S. M. Eley, and R. W. Titball. 1995. Active immunization with recombinant V antigen from Yersinia pestis protects mice against plague. Infect. Immun. 63:2854-2858.
    • (1995) Infect. Immun , vol.63 , pp. 2854-2858
    • Leary, S.E.C.1    Williamson, E.D.2    Griffin, K.F.3    Russell, P.4    Eley, S.M.5    Titball, R.W.6
  • 43
    • 23944461624 scopus 로고    scopus 로고
    • Sequence variation and immunologic cross-reactivity among Babesia bovis merozoite surface antigen 1 proteins from vaccine strains and vaccine breakthrough isolates
    • Leroith, T., K. A. Brayton, J. B. Molloy, R. E. Bock, S. A. Hines, A. E. Lew, and T. F. McElwain. 2005. Sequence variation and immunologic cross-reactivity among Babesia bovis merozoite surface antigen 1 proteins from vaccine strains and vaccine breakthrough isolates. Infect. Immun. 73:5388-5394.
    • (2005) Infect. Immun , vol.73 , pp. 5388-5394
    • Leroith, T.1    Brayton, K.A.2    Molloy, J.B.3    Bock, R.E.4    Hines, S.A.5    Lew, A.E.6    McElwain, T.F.7
  • 44
    • 34848862803 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum AnkA secreted by type IV secretion system is tyrosine phosphorylated by Abl-1 to facilitate infection
    • Lin, M., A. den Dulk-Ras, P. J. Hooykaas, and Y. Rikihisa. 2007. Anaplasma phagocytophilum AnkA secreted by type IV secretion system is tyrosine phosphorylated by Abl-1 to facilitate infection. Cell. Microbiol. 9:2644-2657.
    • (2007) Cell. Microbiol , vol.9 , pp. 2644-2657
    • Lin, M.1    den Dulk-Ras, A.2    Hooykaas, P.J.3    Rikihisa, Y.4
  • 45
    • 40849085144 scopus 로고    scopus 로고
    • High-throughput identification of T-lymphocyte antigens from Anaplasma marginale expressed using in vitro transcription and translation
    • Lopez, J. E., P. A. Beare, R. A. Heinzen, J. Norimine, K. K. Lahmers, G. H. Palmer, and W. C. Brown. 2008. High-throughput identification of T-lymphocyte antigens from Anaplasma marginale expressed using in vitro transcription and translation. J. Immunol. Methods 332:129-141.
    • (2008) J. Immunol. Methods , vol.332 , pp. 129-141
    • Lopez, J.E.1    Beare, P.A.2    Heinzen, R.A.3    Norimine, J.4    Lahmers, K.K.5    Palmer, G.H.6    Brown, W.C.7
  • 46
    • 34248341795 scopus 로고    scopus 로고
    • Immunogenicity of Anaplasma marginale type IV secretion system proteins in a protective outer membrane vaccine
    • Lopez, J. E., G. H. Palmer, K. A. Brayton, M. J. Dark, S. E. Leach, and W. C. Brown. 2007. Immunogenicity of Anaplasma marginale type IV secretion system proteins in a protective outer membrane vaccine. Infect. Immun. 75:2333-2342.
    • (2007) Infect. Immun , vol.75 , pp. 2333-2342
    • Lopez, J.E.1    Palmer, G.H.2    Brayton, K.A.3    Dark, M.J.4    Leach, S.E.5    Brown, W.C.6
  • 47
    • 28444444136 scopus 로고    scopus 로고
    • Identification of novel antigenic proteins in a complex Anaplasma marginale outer membrane immunogen by mass spectrometry and genomic mapping
    • Lopez, J. E., W. F. Siems, K. A. Brayton, G. H. Palmer, T. C. McGuire, and W. C. Brown. 2005. Identification of novel antigenic proteins in a complex Anaplasma marginale outer membrane immunogen by mass spectrometry and genomic mapping. Infect. Immun. 73:8109-8118.
    • (2005) Infect. Immun , vol.73 , pp. 8109-8118
    • Lopez, J.E.1    Siems, W.F.2    Brayton, K.A.3    Palmer, G.H.4    McGuire, T.C.5    Brown, W.C.6
  • 48
    • 40749087672 scopus 로고    scopus 로고
    • Physical linkage of naturally complexed bacterial outer membrane proteins enhances immunogenicity
    • Macmillan, H., J. Norimine, K. A. Brayton, G. H. Palmer, and W. C. Brown. 2008. Physical linkage of naturally complexed bacterial outer membrane proteins enhances immunogenicity. Infect. Immun. 76:1223-1229.
    • (2008) Infect. Immun , vol.76 , pp. 1223-1229
    • Macmillan, H.1    Norimine, J.2    Brayton, K.A.3    Palmer, G.H.4    Brown, W.C.5
  • 49
    • 0037244272 scopus 로고    scopus 로고
    • Conservation of gene conversion mechanism in two distantly related paralogues of Anaplasma marginale
    • Meeus, P. F. M., K. A. Brayton, G. H. Palmer, and A. F. Barbet. 2003. Conservation of gene conversion mechanism in two distantly related paralogues of Anaplasma marginale. Mol. Microbiol. 47:633-643.
    • (2003) Mol. Microbiol , vol.47 , pp. 633-643
    • Meeus, P.F.M.1    Brayton, K.A.2    Palmer, G.H.3    Barbet, A.F.4
  • 51
    • 33644821065 scopus 로고    scopus 로고
    • Differential expression of VirB9 and VirB6 during the life cycle of Anaplasma phagocytophilum in human leukocytes is associated with differential binding and avoidance of lysosome pathway
    • Niu, H., Y. Rikihisa, M. Yamaguchi, and N. Ohashi. 2006. Differential expression of VirB9 and VirB6 during the life cycle of Anaplasma phagocytophilum in human leukocytes is associated with differential binding and avoidance of lysosome pathway. Cell. Microbiol. 8:523-534.
    • (2006) Cell. Microbiol , vol.8 , pp. 523-534
    • Niu, H.1    Rikihisa, Y.2    Yamaguchi, M.3    Ohashi, N.4
  • 52
    • 42949089411 scopus 로고    scopus 로고
    • Composition of the surface proteome of Anaplasma marginale and its role in protective immunity induced by outer membrane immunization
    • Noh, S., K. A. Brayton, W. C. Brown, J. Norimine, G. R. Munske, C. M. Davitt, and G. H. Palmer. 2008. Composition of the surface proteome of Anaplasma marginale and its role in protective immunity induced by outer membrane immunization. Infect. Immun. 76:2219-2226.
    • (2008) Infect. Immun , vol.76 , pp. 2219-2226
    • Noh, S.1    Brayton, K.A.2    Brown, W.C.3    Norimine, J.4    Munske, G.R.5    Davitt, C.M.6    Palmer, G.H.7
  • 54
    • 0041823439 scopus 로고    scopus 로고
    • Stimulation of T-helper cell gamma interferon and immunoglobulin G responses specific for Babesia bovis rhoptryassociated protein 1 (RAP-1) or a RAP-1 protein lacking the carboxyterminal repeat region is insufficient to provide protective immunity against virulent challenge
    • Norimine, J., J. Mosqueda, C. Suarez, G. H. Palmer, T. F. McElwain, G. Mbassa, and W. C. Brown. 2003. Stimulation of T-helper cell gamma interferon and immunoglobulin G responses specific for Babesia bovis rhoptryassociated protein 1 (RAP-1) or a RAP-1 protein lacking the carboxyterminal repeat region is insufficient to provide protective immunity against virulent challenge. Infect. Immun. 71:5021-5032.
    • (2003) Infect. Immun , vol.71 , pp. 5021-5032
    • Norimine, J.1    Mosqueda, J.2    Suarez, C.3    Palmer, G.H.4    McElwain, T.F.5    Mbassa, G.6    Brown, W.C.7
  • 55
    • 0036126936 scopus 로고    scopus 로고
    • Characterization and transcriptional analysis of gene clusters for a type IV secretion machinery in human granulocytic and monocytic ehrlichiosis agents
    • Ohashi, N., N. Zhi, Q. Lin, and Y. Rikihisa. 2002. Characterization and transcriptional analysis of gene clusters for a type IV secretion machinery in human granulocytic and monocytic ehrlichiosis agents. Infect. Immun. 70: 2128-2138.
    • (2002) Infect. Immun , vol.70 , pp. 2128-2138
    • Ohashi, N.1    Zhi, N.2    Lin, Q.3    Rikihisa, Y.4
  • 57
    • 0022461701 scopus 로고
    • Immunization with an isolate-common surface protein protects cattle against anaplasmosis
    • Palmer, G. H., A. F. Barbet, W. C. Davis, and T. C. McGuire. 1986. Immunization with an isolate-common surface protein protects cattle against anaplasmosis. Science 231:1299-1302.
    • (1986) Science , vol.231 , pp. 1299-1302
    • Palmer, G.H.1    Barbet, A.F.2    Davis, W.C.3    McGuire, T.C.4
  • 58
    • 34547962985 scopus 로고    scopus 로고
    • Gene conversion is a convergent strategy for antigenic variation
    • Palmer, G. H., and K. A. Brayton. 2007. Gene conversion is a convergent strategy for antigenic variation. Trends Parasitol. 23:408-413.
    • (2007) Trends Parasitol , vol.23 , pp. 408-413
    • Palmer, G.H.1    Brayton, K.A.2
  • 59
    • 0034093410 scopus 로고    scopus 로고
    • Antigenic variation in the persistence and transmission of the ehrlichia Anaplasma marginale
    • Palmer, G. H., W. C. Brown, and F. R. Rurangirwa. 2000. Antigenic variation in the persistence and transmission of the ehrlichia Anaplasma marginale. Microbes Infect. 2:1-10.
    • (2000) Microbes Infect , vol.2 , pp. 1-10
    • Palmer, G.H.1    Brown, W.C.2    Rurangirwa, F.R.3
  • 60
    • 0028918513 scopus 로고
    • Molecular basis for vaccine development against anaplasmosis and babesiosis
    • Palmer, G. H., and T. F. McElwain. 1995. Molecular basis for vaccine development against anaplasmosis and babesiosis. Vet. Parasitol. 57:233-253.
    • (1995) Vet. Parasitol , vol.57 , pp. 233-253
    • Palmer, G.H.1    McElwain, T.F.2
  • 61
    • 0027981121 scopus 로고
    • Heterologous strain challenge of cattle immunized with Anaplasma marginale outer membranes
    • Palmer, G. H., D. Munodzana, N. Tebele, T. Ushe, and T. F. McElwain. 1994. Heterologous strain challenge of cattle immunized with Anaplasma marginale outer membranes. Vet. Immunol. Immunopathol. 42:265-273.
    • (1994) Vet. Immunol. Immunopathol , vol.42 , pp. 265-273
    • Palmer, G.H.1    Munodzana, D.2    Tebele, N.3    Ushe, T.4    McElwain, T.F.5
  • 62
    • 0023876007 scopus 로고
    • Immunization of cattle with a 36-kilodalton surface protein induces protection against homologous and heterologous Anaplasma marginale challenge
    • Palmer, G. H., S. M. Oberle, A. F. Barbet, W. L. Goff, W. C. Davis, and T. C. McGuire. 1988. Immunization of cattle with a 36-kilodalton surface protein induces protection against homologous and heterologous Anaplasma marginale challenge. Infect. Immun. 56:1526-1531.
    • (1988) Infect. Immun , vol.56 , pp. 1526-1531
    • Palmer, G.H.1    Oberle, S.M.2    Barbet, A.F.3    Goff, W.L.4    Davis, W.C.5    McGuire, T.C.6
  • 63
    • 0033168918 scopus 로고    scopus 로고
    • Molecular basis for vaccine development against Anaplasma marginale
    • Palmer, G. H., F. R. Ruringirwa, K. M. Kocan, and W. C. Brown. 1999. Molecular basis for vaccine development against Anaplasma marginale. Parasitol. Today 15:281-286.
    • (1999) Parasitol. Today , vol.15 , pp. 281-286
    • Palmer, G.H.1    Ruringirwa, F.R.2    Kocan, K.M.3    Brown, W.C.4
  • 64
    • 4143085008 scopus 로고    scopus 로고
    • Anaplasma phagocytophilum AnkA binds to granulocyte DNA and nuclear proteins
    • Park, J., K. J. Kim, K.-S. Hoi, D. J. Grab, and J. S. Dumler. 2004. Anaplasma phagocytophilum AnkA binds to granulocyte DNA and nuclear proteins. Cell. Microbiol. 6:743-751.
    • (2004) Cell. Microbiol , vol.6 , pp. 743-751
    • Park, J.1    Kim, K.J.2    Hoi, K.-S.3    Grab, D.J.4    Dumler, J.S.5
  • 65
    • 3042849127 scopus 로고    scopus 로고
    • Characterization of lymphocyte subpopulations and major histocompatibility complex haplotypes of mastitisresistant and susceptible cows
    • Park, Y. H., Y. S. Joo, J. Y. Park, J. S. Moon, S. H. Kim, N. H. Kwon, J. S. Ahn, W. C. Davis, and C. J. Davies. 2004. Characterization of lymphocyte subpopulations and major histocompatibility complex haplotypes of mastitisresistant and susceptible cows. J. Vet. Sci. 5:29-39.
    • (2004) J. Vet. Sci , vol.5 , pp. 29-39
    • Park, Y.H.1    Joo, Y.S.2    Park, J.Y.3    Moon, J.S.4    Kim, S.H.5    Kwon, N.H.6    Ahn, J.S.7    Davis, W.C.8    Davies, C.J.9
  • 66
    • 0031037305 scopus 로고    scopus 로고
    • Characterization of membrane and protein interaction determinants of the Agrobacterium tumefaciens VirB11 ATPase
    • Rashkova, S., G. M. Spudich, and P. J. Christie. 1997. Characterization of membrane and protein interaction determinants of the Agrobacterium tumefaciens VirB11 ATPase. J. Bacteriol. 179:583-591.
    • (1997) J. Bacteriol , vol.179 , pp. 583-591
    • Rashkova, S.1    Spudich, G.M.2    Christie, P.J.3
  • 67
    • 0033120134 scopus 로고    scopus 로고
    • Association of the bovine major histocompatibility complex DRB3 (BoLA-DRB3) with production traits in Canadian dairy cattle
    • Sharif, S., B. A. Mallard, B. N. Wilkie, J. M. Sargeant, H. M. Scott, J. C. Dekkers, and K. E. Leslie. 1999. Association of the bovine major histocompatibility complex DRB3 (BoLA-DRB3) with production traits in Canadian dairy cattle. Anim. Genet. 30:157-160.
    • (1999) Anim. Genet , vol.30 , pp. 157-160
    • Sharif, S.1    Mallard, B.A.2    Wilkie, B.N.3    Sargeant, J.M.4    Scott, H.M.5    Dekkers, J.C.6    Leslie, K.E.7
  • 68
    • 0029795239 scopus 로고    scopus 로고
    • Intermolecular disulfide bonds stabilize VirB7 homodimers and VirB7/VirB9 heterodimers during biogenesis of the Agrobacterium tumefaciens T-complex transport apparatus
    • Spudich, G. M., D. Fernandez, X. R. Zhou, and P. J. Christie. 1996. Intermolecular disulfide bonds stabilize VirB7 homodimers and VirB7/VirB9 heterodimers during biogenesis of the Agrobacterium tumefaciens T-complex transport apparatus. Proc. Natl. Acad. Sci. U. S. A. 93:7512-7517.
    • (1996) Proc. Natl. Acad. Sci. U. S. A , vol.93 , pp. 7512-7517
    • Spudich, G.M.1    Fernandez, D.2    Zhou, X.R.3    Christie, P.J.4
  • 69
    • 20444410858 scopus 로고    scopus 로고
    • Yersinia pestis Yop secretion protein F: Purification, characterization, and protective efficacy against bubonic plague
    • Swietnicki, W., B. S. Powell, and J. Goodin. 2005. Yersinia pestis Yop secretion protein F: purification, characterization, and protective efficacy against bubonic plague. Protein Expr. Purif. 42:166-172.
    • (2005) Protein Expr. Purif , vol.42 , pp. 166-172
    • Swietnicki, W.1    Powell, B.S.2    Goodin, J.3
  • 70
    • 0025800571 scopus 로고
    • Induction of protective immunity using Anaplasma marginale initial body membranes
    • Tebele, N., T. C. McGuire, and G. H. Palmer. 1991. Induction of protective immunity using Anaplasma marginale initial body membranes. Infect. Immun. 59:3199-3204.
    • (1991) Infect. Immun , vol.59 , pp. 3199-3204
    • Tebele, N.1    McGuire, T.C.2    Palmer, G.H.3
  • 72
    • 0027029189 scopus 로고
    • Extensive polymorphism of the BoLA-DRB3 gene distinguished by PCR-RFLP
    • van Eijk, M. J., J. A. Stewart-Haynes, and H. A. Lewin. 1992. Extensive polymorphism of the BoLA-DRB3 gene distinguished by PCR-RFLP. Anim. Genet. 23:483-496.
    • (1992) Anim. Genet , vol.23 , pp. 483-496
    • van Eijk, M.J.1    Stewart-Haynes, J.A.2    Lewin, H.A.3
  • 73
    • 47949103935 scopus 로고    scopus 로고
    • Vidotto, M. C., E. J. Venancio, and O. Vidotto. 2008. Cloning, sequencing, and antigenic characterization of rVirB9 of Anaplasma marginale isolated from Parana State, Brazil. Gen. Mol. Res. 7:460-466.
    • Vidotto, M. C., E. J. Venancio, and O. Vidotto. 2008. Cloning, sequencing, and antigenic characterization of rVirB9 of Anaplasma marginale isolated from Parana State, Brazil. Gen. Mol. Res. 7:460-466.
  • 74
    • 19344378727 scopus 로고    scopus 로고
    • Wu, M., L. V. Sun, J. Vamathevan, M. Riegler, R. Deboy, J. C. Brownlie, E. A. McGraw, M. Martin, C. Esser, N. Ahmadinejad, C. Wiegand, R. Madupu, M. J. Beanan, L. M. Brikac, S. C. Daughtery, A. S. Durkin, J. F. Kolonay, W. C. Nelson, Y. Mohamoud, P. Lee, K. Berry, M. B. Young, T. Utterback, J. Weidman, W. C. Nierman, I. T. Paulsen, K. E. Nelson, H. Tettelin, S. L. O'Neill, and J. A. Eisen. 2004. Phylogenomics of the reproductive parasite Wolbachia pipentis wMel: a streamlined genome overrun by mobile genetic elements. PLoS Biol. 2:E69.
    • Wu, M., L. V. Sun, J. Vamathevan, M. Riegler, R. Deboy, J. C. Brownlie, E. A. McGraw, M. Martin, C. Esser, N. Ahmadinejad, C. Wiegand, R. Madupu, M. J. Beanan, L. M. Brikac, S. C. Daughtery, A. S. Durkin, J. F. Kolonay, W. C. Nelson, Y. Mohamoud, P. Lee, K. Berry, M. B. Young, T. Utterback, J. Weidman, W. C. Nierman, I. T. Paulsen, K. E. Nelson, H. Tettelin, S. L. O'Neill, and J. A. Eisen. 2004. Phylogenomics of the reproductive parasite Wolbachia pipentis wMel: a streamlined genome overrun by mobile genetic elements. PLoS Biol. 2:E69.
  • 75
    • 0036168327 scopus 로고    scopus 로고
    • Strong CD8 T-cell responses following coimmunization with plasmids expressing the dominant pp89 and subdominant M84 antigens of murine cytomegalovirus correlate with long-term protection against subsequent viral challenge
    • Ye, M., C. S. Morello, and D. H. Spector. 2002. Strong CD8 T-cell responses following coimmunization with plasmids expressing the dominant pp89 and subdominant M84 antigens of murine cytomegalovirus correlate with long-term protection against subsequent viral challenge. J. Virol. 76:2100-2112.
    • (2002) J. Virol , vol.76 , pp. 2100-2112
    • Ye, M.1    Morello, C.S.2    Spector, D.H.3


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