Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: Unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new species combinations and designation of Ehrlichia equi and 'HGE agent' as subjective synonyms of Ehrlichia phagocytophila

International Journal of Systematic and Evolutionary Microbiology

Volumn 51, Issue 6, 2001, Pages 2145-2165

  Dumler, J S ^a   Barbet, A F ^a   Bekker, C P J ^a   Dasch, G A ^a   Palmer, G H ^a   Ray, S C ^a   Rikihisa, Y ^a   Rurangirwa, F R ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

Anaplasma; Anaplasmataceae; Cowdria; Ehrlichia; Neorickettsia

Indexed keywords

BACTERIAL ANTIGEN; MEMBRANE PROTEIN; RNA 16S;

ANAPLASMA; ANAPLASMA PHAGOCYTOPHILUM; ANAPLASMATACEAE; CELL VACUOLE; CONTROLLED STUDY; ECOLOGY; EHRLICHIA; EHRLICHIOSIS; EUKARYOTIC CELL; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC PROCEDURES; MORPHOLOGY; NEORICKETTSIA RISTICII; NEORICKETTSIA SENNETSU; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PRIORITY JOURNAL; REVIEW; RICKETTSIACEAE; RICKETTSIALES; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE; TAXONOMY; UNINDEXED SEQUENCE; WOLBACHIA;

ANAPLASMA; ANAPLASMA BOVIS; ANAPLASMA PHAGOCYTOPHILA; ANAPLASMA PHAGOCYTOPHILUM; ANAPLASMA PLATYS; ANAPLASMATACEAE; BACTERIA (MICROORGANISMS); COWDRIA; COWDRIA RUMINANTIUM; EHRLICHIA; EHRLICHIA BOVIS; EHRLICHIA EQUI; EHRLICHIA PHAGOCYTOPHILA; EHRLICHIA PLATYS; EHRLICHIA RISTICII; EHRLICHIA RUMINANTIUM; EHRLICHIA SENNETSU; EUKARYOTA; NEORICKETTSIA; NEORICKETTSIA RISTICII; NEORICKETTSIA SENNETSU; PROKARYOTA; RICKETTSIACEAE; RICKETTSIALES; WOLBACHIA; WOLBACHIEAE;

EID: 0035192367     PISSN: 14665026     EISSN: None     Source Type: Journal    
DOI: 10.1099/00207713-51-6-2145     Document Type: Review

References (198)

1. Identification of antigens of two isolates of Anaplasma marginale, using a western blot technique
2. Human granulocytic ehrlichiosis: A case series from a medical center in New York State
3. Evaluation of Anaplasma marginale major surface protein 3 (MSP3) as a diagnostic test antigen
4. Anaplasma marginale major surface protein 3 is encoded by a polymorphic, multigene family
5. Different organisms associated with heartwater as shown by analysis of 16S ribosomal RNA gene sequences
6. Ehrlichia chaffeensis, a new species associated with human ehrlichiosis
7. Ehrlichia ewingii, sp. nov., the etiologic agent of canine granulocytic ehrlichiosis
8. Experimental transmission of a granulocytic form of the tribe Ehrlichieae by Dermacentor variabilis and Amblyomma americanum to dogs
9. Antigenic diversity of granulocytic Ehrlichia isolates from humans in Wisconsin and New York and a horse in California
10. Human granulocytic ehrlichiosis in the upper midwest United States. A new species emerging?
11. Clinical and laboratory characteristics of human granulocytic ehrlichiosis
12. Seroprevalence of human granulocytic ehrlichiosis among permanent residents of northwestern Wisconsin
13. Phylogeny of Wolbachia in filarial nematodes
14. Recent developments in the molecular biology of anaplasmosis
15. Size variation of the major immunodominant protein of Cowdria ruminantium
16. Protection against Ehrlichia equi is conferred by prior infection with the human granulocytotropic ehrlichia (HGE agent)
17. Detection of Ehrlichia risticii, the agent of Potomac horse fever, in freshwater stream snails (Pleuroceridae: Juga spp.) from northern California
18. Abrogation of gamma interferon-induced inhibition of Ehrlichia chaffeensis infection in human monocytes with iron-transferrin
19. Prevalence of granulocytic Ehrlichia infection among white-tailed deer in Wisconsin
20. Natural transmission of heartwater
21. In vitro cultivation of Cowdria ruminantium
22. Proposals to unify the genera Grahamella and Bartonella, with descriptions of Bartonella talpae comb. nov., Bartonella peromysci comb. nov., and three new species, Bartonella grahamii sp. nov., Bartonella and Bartonella doshiae sp. nov
23. Clinical ehrlichiosis in a cat
24. Potential value of major antigenic protein 2 for serological diagnosis of heartwater and related ehrlichial infections
25. Proposals to unify the genera Bartonella and Rochalimaea, with descriptions of Bartonella quintana comb. nov., Bartonella vinsonii comb. nov., Bartonella henselae comb. nov., and Bartonella elizabethae comb. the family Bartonellaceae from the order Rickettsiales
26. Antigenic characterization of ehrlichiae: Protein immunoblotting of Ehrlichia canis, Ehrlichia sennetsu, and Ehrlichia risticii
27. Serologic diagnosis of human monocytic ehrlichiosis by immunoblot analysis
28. Ehrlichia ewingii, a newly recognized agent of human ehrlichiosis
29. Heartwater in Guadeloupe and in the Caribbean
30. ankA: An Ehlrichia phagocytophila group gene encoding a cytoplasmic protein antigen with ankyrin repeats
31. Antigenic, morphologic, and molecular characterization of new Ehrlichia risticii isolates
32. Identification of a granulocytotropic Ehrlichia species as the etiologic agent of human disease
33. Identification of the antigenic constituents of Ehrlichia chaffeensis
34. Analysis and ultrastructural localization of Ehrlichia chaffeensis proteins with monoclonal antibodies
35. Genetic and antigenic diversity of Ehrlichia chaffeensis: Comparative analysis of a novel human strain from Oklahoma and previously isolated strains
36. Studies on the aetiology of heartwater. I. Observation of a rickettsia, Rickettsia ruminantium (n. sp.) in the tissues of infected animals
37. Studies on the aetiology of heartwater: III. The multiplication of Rickettsia ruminantium within the endothelial cells of infected animals and their discharge into the circulation
38. Phylogenetic relationship of Cowdria ruminantium, agent of heartwater, to Anaplasma marginale and other members of the order Rickettsiales determined on the basis of 16S rRNA sequence
39. Susceptibility of dogs to infection with Ehrlichia chaffeensis, causative agent of human ehrlichiosis
40. Serologic diagnosis of human ehrlichiosis using two Ehrlichia canis isolates
41. Isolation and characterization of an Ehrlichia sp. from a patient diagnosed with human ehrlichiosis
42. The interface between research and the diagnosis of an emerging tick-borne disease, human ehrlichiosis due to Ehrlichia chaffeensis
43. Polymerase chain reaction evidence of Ehrlichia chaffeensis, an etiologic agent of human ehrlichiosis in dogs from southeast Virginia
44. Ehrlichia-like 16S rDNA sequence from wild white-tailed deer (Odocoileus virginianus)
45. Wolbachia infections are distributed throughout insect somatic and germ line tissues
46. Existence en Algérie d'une Rickettsia du chien
47. Rickettsia bovis. Nouvelle espèce pathogène pour le boeuf
48. Taxonomic position of the rickettsiae: Current knowledge
49. Serologic cross-reactions among Ehrlichia equi, Ehrlichia phagocytophila, and the human granulocytic ehrlichia
50. Heartwater serology: Some problems with the interpretations of results
51. Impact of persistent Anaplasma marginale rickettsemia on tick infection and transmission
52. A new strain of Ehrlichia canis
53. Experimental transmission of Ehrlichia chaffeensis (Rickettsiales: Ehrlichieae) among white-tailed deer by Amblyomma americanum (Acari: Ixodidae)
54. Confidence limits on phylogenies: An approach using the bootstrap
55. Host cell defense factors in the growth of Ehrlichia chaffeensis in different monocyte cell lines
56. Human ehrlichiosis in the United States, 1985 to 1990
57. Studies on the infectious agent of tick-borne fever in sheep
58. Ehrlichia spp. in cervids from California
59. Human granulocytic ehrlichiosis in northern California: Two case descriptions with genetic analysis of the ehrlichiae
60. Analysis of 16S ribosomal DNA sequences of Francisella strains and utilization for determination of the phylogeny of the genus and for identification of strains by PCR
61. Observations on ovine strains of tick-borne fever
62. Expression of Anaplasma marginale major surface protein 2 variants during persistent cyclic rickettsemia
63. Neorickettsia-like organism isolated from metacercaria of a fluke, Stellantchasmus falcatus
64. Direct cultivation of the causative agent of human granulocytic ehrlichiosis
65. 'Tick-borne fever'. (A hitherto undescribed disease of sheep)
66. Geographic, clinical, serologic, and molecular evidence of granulocytic ehrlichiosis a likely zoonotic disease, in Minnesota and Wisconsin dogs
67. Equine ehrlichiosis
68. Transmission of Ehrlichia canis to dogs by ticks (Rhipicephalus sanguineus)
69. Propagation of granulocytic Ehrlichia spp. from human and equine sources in HL-60 cells induced to differentiate into functional granulocytes
70. A single tissue culture system for the propagation of the agents of the human ehrlichioses
71. Intracellular parasitism by the human granulocytic ehrlichiosis bacterium through the P-selectin ligand, PSGL-1
72. The rickettsia, Wolbachia pipientis (gen. et sp. n.) and associated inclusions in the mosquito, Culex pipiens
73. Isolation, experimental transmission, and characterization of causative agent of Potomac horse fever
74. Ehrlichia risticii sp. nov.: Etiological agent of equine monocytic ehrlichiosis (synonym, Potomac horse fever)
75. The recognition of tick-borne fever as a disease of cattle
76. Canine ehrlichiosis (tropical canine pancytopenia): A review
77. Cloning of the gene encoding the 44-kilodalton antigen of the agent of human granulocytic ehrlichiosis and characterization of the humoral response
78. Estimation of the transition/transversion ratio
79. Comparison of PCR with other tests for early diagnosis of canine ehrlichiosis
80. Identification of an immunodominant antigenically conserved 32-kilodalton protein from Cowdria ruminantium
81. Serotypes in Cowdria ruminantium and their relationship with Ehrlichia phagocytophila determined by immunofluorescence
82. The immunodominant 32-kilodalton protein of Cowdria ruminantium is conserved with the genus Ehrlichia
83. Comparison of Ehrlichia muris strains isolated from wild mice and ticks and serologic survey of humans and animals with E. muris as antigen
84. Serological evidence for antigenic relationships between Ehrlichia canis and Cowdria ruminantium
85. In vitro cultivation of Anaplasma marginale: Growth pattern and morphologic appearance
86. Characterization of monoclonal antibodies to the 44-kilodalton major outer membrane protein of the human granulocytic ehrlichiosis agent
87. Primary bone marrow progenitors of both granulocytic and monocytic lineages are susceptible to infection with the agent of human granulocytic ehrlichiosis
88. Development of Anaplasma marginale in male Dermacentor andersoni transferred from parasitemic to susceptible cattle
89. Anaplasma infections in wild and domestic ruminants: A review
90. The Cowdria ruminantium groE operon
91. Isolation of Ehrlichia chaffeensis from wild white-tailed deer (Odocoileus virginianus) confirms their role as natural reservoir hosts
92. The development of Cowdria ruminantium in neutrophils
93. Molecular cloning of the gene for a conserved major immunoreactive 28-kilodalton protein of Ehrlichia canis: A potential serodiagnostic antigen
94. Modern trends in animal health and husbandry. Some infectious diseases of free-living wildlife
95. Characterization of hemagglutinating components on the Anaplasma marginale initial body surface and identification of possible adhesins
96. Common and isolate-restricted antigens of Anaplasma marginale detected with monoclonal antibodies
97. Studies in tick-borne fever of sheep. I. Transmission by the tick, Ixodes ricinus, with a description of the disease produced
98. Equine ehrlichiosis
99. Transmission and passage in horses of the agent of human granulocytic ehrlichiosis
100. Identification of an enzootic diarrhea ('Shasta River Crud') in Northern California as Potomac horse fever
101. Transmission of Ehrlichia risticii, the agent of Potomac horse fever, using naturally infected aquatic insects and helminth vectors: Preliminary report
102. Infections of granulocytic ehrlichiae and Borrelia burgdorferi in white-tailed deer in Connecticut
103. An immunoblotting diagnostic assay for heartwater based on the immunodominant 32-kilodalton protein of Cowdria ruminantium detects false positives in field sera
104. Molecular cloning of a gene encoding the immunogenic 21 kDa protein of Cowdria ruminantium
105. Sequence analysis of the ank gene of granulocytic ehtlichiae
106. Studies on infectious mononucleosis (glandular fever). I. Isolation of etiologic agent from blood, bone marrow and lymph node of a patient with infectious mononucleosis by using mice
107. Cytotropic inducers of infection and the classification of the Rickettsiae with Chlamydozoa
108. Comments by readers
109. Isolation of the equine granulocytic ehrlichiosis agent, Ehrlichia equi, in tick cell culture
110. Establishment of the tick (Acari: Ixodidae)-borne cattle pathogen Anaplasma marginale (Rickettsiales: Anaplasmataceae) in tick cell culture
111. Major antigenic proteins of the agent of human granulocytic ehrlichiosis are encoded by members of a multi gene family
112. The cell wall-less rickettsia Eperythrozoon wenyonii is a Mycoplasma
113. The blesbuck (Damaliscus albifrons) as a carrier of heartwater and blue tongue
114. The blesbuck (Damaliscus albifrons) and the black wildebeest as carriers of heartwater
115. Dusky-footed wood rats (Neotoma fuscipes) as reservoirs of granulocytic ehrlichiae (Rickettsiales: Ehrlichieae) in northern California
116. Characterization of an endosymbiont infecting wood ticks, Dermacentor andersoni, as a member of the genus Francisella
117. Endosymbionts of ticks and their relationship to Wolbachia spp. and tick-borne pathogens of humans and animals
118. Immunodominant major outer membrane proteins of Ehrlichia chaffeensis are encoded by a polymorphic multigene family
119. Cloning and characterization of multi genes encoding the immunodominant 30-kilodalton major outer membrane proteins of Ehrlichia canis and application of the recombinant protein for serodiagnosis
120. 16S rRNA phylogenetic analysis of the bacterial endosymbionts associated with cytoplasmic incompatibility in insects
121. Presence of common antigens, including major surface protein epitopes, between the cattle (intraerythrocytic) and tick stages of Anaplasma marginale
122. Recognition of conserved surface protein epitopes on Anaplasma centrale and Anaplasma marginale isolates from Israel, Kenya and the United States
123. Persistence of Anaplasma ovis infection and conservation of the msp-2 and msp-3 multigene families within the genus Anaplasma
124. Ehrlichia canis-like agent isolated from a man in Venezuela: Antigenic and genetic characterization
125. Demonstration of a carrier state for Cowdria ruminantium in wild ruminants from Africa
126. Cowdria ruminantium, infection in ticks in the Kruger National Park
127. Neorickettsia helminthoeca, a new rickettsia-like disease agent in dogs in western United States transmitted by an helminth. Riass Commun VI
128. Ultrastructural differentiation of the genogroups in the genus Ehrlichia
129. 16S rRNA gene sequence of Neorickettsia helminthoeca and its phylogenetic alignment with members of the genus Ehrlichia
130. Heartwater. The development and life cycle of Cowdria ruminantium in the vertebrate host, ticks and cultured endothelial cells
131. Granulocytic ehrlichiosis in two dogs in Switzerland
132. Rickettsial diseases of the Far East: New perspectives
133. Characterization of monoclonal antibodies to an immunodominant protein of the etiologic agent of human granulocytic ehrlichiosis
134. Variability in the 28-kDa surface antigenic protein multigene locus of isolates of the emerging disease agent Ehrlichia chaffeensis suggests that it plays a role in immune evasion
135. Molecular characterization of a 28 kDa surface antigen gene family of the tribe Ehrlichiae
136. Production and characterization of Ehrlichia risticii, the agent of Potomac horse fever, from snails (Pleuroceridae: Juga spp.) in aquarium culture and genetic comparison to equine strains
137. Experimental transmission of Ehrlichia equi to horses through naturally infected ticks (Ixodes pacificus) from northern California
138. Ixodes pacificus as a vector of Ehrlichia equi
139. The tribe Ehrlichieae and ehrlichial diseases
140. Cross-reacting antigens between Neorickettsia helminthoeca and Ehrlichia species shown by immunofluorescence and Western immunoblotting
141. Causative ehrlichial organisms in Potomac horse fever
142. Clinical, histopathological, and immunological responses of ponies to Ehrlichia sennetsu and subsequent Ehrlichia risticii challenge
143. Isolation and continuous culture of Neorickettsia helminthoeca in a macrophage cell line
144. Analyses of Ehrlichia canis and a canine granulocytic Ehrlichia infection
145. Western immunoblot analysis of Ehrlichia chaffeensis E. canis or E. ewingii, infections in dogs and humans
146. 2+ and calmodulin in ehrlichial infection in macrophages
147. Western immunoblot analysis of Haemobartonella muris and comparison of 16S rRNA gene sequences of H. muris, H. felis, and Eperythrozoon suis
148. AL
149. AL
150. Evidence of a serologic relationship between Ehrlichia canis and Rickettsia sennetsu
151. Diagnosis of equine monocytic ehrlichiosis (Potomac horse fever) by indirect immunofluorescence
152. Identification of the antigenic proteins of Cowdria ruminantium
153. Phylogenetic analysis of the genus Rickettsia by 16S rDNA sequencing
154. Phylogenetic analysis and taxonomic relationships among the genus Rickettsia
155. Reassessment of the taxonomic position of Rickettsiella grylli
156. Determination of the genome size of Ehrlichia spp., using pulsed field gel electrophoresis
157. Fluorescent antibody technique to detect Cowdria ruminantium in in vitro-cultured macrophages and buffy coats from cattle, sheep, and goats
158. Lesser-known rickettsias infecting livestock
159. Antigenic and genomic relatedness among Ehrlichia risticii, Ehrlichia sennetsu, and Ehrlichia canis
160. New Ehrlichia species closely related to Ehrlichia chaffeensis isolated from Ixodes ovatus ticks in Japan
161. On the naming of rickettsiae after Paul Ehrlich
162. Equine ehrlichiosis: A disease with similarities to tick-borne fever and bovine petechial fever
163. Molecular cloning and sequencing of three granulocytic Ehrlichia genes encoding high-molecular-weight immunoreactive proteins
164. PCR amplification and comparison of nucleotide sequences from the groESL heat shock operon of Ehrlichia species
165. Effect of cyclophosphamide on the growth of Rickettsia sennetsu in experimentally infected mice
166. Purification of complement-fixing antigens of Rickettsia sennetsu by ether treatment
167. Classification of Rickettsia tsutsugamushi in a new genus, Orientia gen. nov., as Orientia tsutsugamushi comb. nov
168. Perpetuation of the agent of human granulocytic ehrlichiosis in a deer tick-rodent cycle
169. Anaplasma marginale (gen. and spec. nov.). The marginal points in the blood of cattle suffering from a specific disease
170. Further investigations into anaplasmosis of South African cattle
171. The CLUSTAL-X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
172. Cytoecetes microti n. gen. n. sp. A parasite developing in granulocytes and infection in small rodents
173. Heartwater (Cowdria ruminantium infection): Current status
174. Phylogenetic analysis of the 16S rDNA of the cytoplasmic bacterium Wolbachia from the novel host Folsomia candida (Hexapoda, Collembola) and its implications for wolbachial taxonomy
175. Intermolecular relationships of major surface proteins of Anaplasma marginale
176. The Anaplasma marginale msp5 gene encodes a 19-kilodalton protein conserved in all recognized Anaplasma species
177. Phylogenetic position of Cowdria ruminantium (Rickettsiales) determined by analysis of amplified 16S ribosomal DNA sequences
178. Molecular cloning, sequence analysis, and expression of the gene encoding the immunodominant 32-kilodalton protein of Cowdria ruminantium
179. In vitro cultivation of Anaplasma marginale in bovine erythrocytes co-cultured with endothelial cells
180. Human monocytic and granulocytic ehrlichioses. Discovery and diagnosis of emerging tick-borne infections and the critical role of the pathologist
181. Natural infection of small mammal species in Minnesota with the agent of human granulocytic ehrlichiosis
182. Serologic evidence of a natural infection of white-tailed deer with the agent of human granulocytic ehrlichiosis in Wisconsin and Maryland
183. Phylogenetic diversity of the Rickettsiae
184. 16S ribosomal DNA amplification for phylogenetic study
185. Ehrlichia muris sp. nov., identified on the basis of 16S rRNA base sequences and serological, morphological, and biological characteristics
186. Diversity of 16S rRNA genes of new Ehrlichia strains isolated from horses with clinical signs of Potomac horse fever
187. Characterization of the SF agent, an Ehrlichia sp. isolated from the fluke Stellantchasmus falcatus by 16S rRNA base sequence, serological, and morphological analyses
188. Wolbachia run amok
189. Towards a natural system of organisms: Proposal for the domains Archaea, Bacteria, and Eukarya
190. Ehrlichial diseases of dogs
191. Detection of Ehrlichia chaffeensis in human tissue by using species specific monoclonal antibody
192. Characterization of the genus-common outer membrane proteins in Ehrlichia
193. Genetic diversity of the 28-kilodalton outer membrane protein gene in human isolates of Ehrlichia chaffeensis
194. Ehrlichia sennetsu groE operon and antigenic properties of the GroEL homolog
195. Comparison of major antigenic proteins of six strains of the human granulocytic ehrlichiosis agent by western immunoblot analysis
196. Cloning and expression of the 44-kilodalton major outer membrane protein gene of the human granulocytic ehrlichiosis agent and application of the recombinant protein to serodiagnosis
197. Phylogeny and PCR-based classification of Wolbachia strains using wsp gene sequences