Mimicking the evolution of a thermally stable monomeric four-helix bundle by fusion of four identical single-helix peptides

Journal of Biochemistry

Volumn 147, Issue 3, 2010, Pages 371-379

  Akanuma, Satoshi ^a   Matsuba, Taku ^a   Ueno, Emi ^a   Umeda, Naoki ^a   Yamagishi, Akihiko ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Four helix bundle; Fusion; Internal symmetry; Tandem duplication; Thermal stability

Indexed keywords

BACTERIAL PROTEIN; BIOMATERIAL; DIMER; DNA BINDING PROTEIN; MONOMER; OLIGOMER; PEPTIDE; POLYPEPTIDE; RECOMBINANT PROTEIN; REPRESSOR PROTEIN; SCAFFOLD PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; ESCHERICHIA COLI; GENE DUPLICATION; MOLECULAR EVOLUTION; NONHUMAN; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN STRUCTURE; REPRESSOR GENE; THERMOSTABILITY;

ESCHERICHIA COLI; EVOLUTION, MOLECULAR; GENE DUPLICATION; HELIX-LOOP-HELIX MOTIFS; LAC REPRESSORS; MODELS, MOLECULAR; PEPTIDES; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; TEMPERATURE;

ESCHERICHIA COLI;

EID: 77249086108     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvp179     Document Type: Article

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