Reduced functional connectivity in a right-hemisphere network for volitional ocular motor control in schizophrenia

Brain

Volumn 133, Issue 2, 2010, Pages 625-637

  Tu, Peichi ^a,b   Buckner, Randy L ^b,c,d   Zollei, Lilla ^b   Dyckman, Kara A ^b   Goff, Donald C ^b   Manoach, Dara S ^b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD UNIVERSITY   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Anterior cingulate cortex; Executive control; FMRI; Saccadic eye movements; Schizophrenia

Indexed keywords

CHLORPROMAZINE;

ADULT; ANISOTROPY; ARTICLE; BRAIN FUNCTION; BRAIN REGION; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MALE; MOTOR PERFORMANCE; NEUROIMAGING; OUTPATIENT; PRIORITY JOURNAL; RIGHT HEMISPHERE; SACCADIC EYE MOVEMENT; SCHIZOPHRENIA; TASK PERFORMANCE; VISUAL FIELD; WHITE MATTER;

EID: 77249085143     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awp317     Document Type: Article

References (103)

1. Agartz I, Andersson JL, Skare S. Abnormal brain white matter in schizophrenia: a diffusion tensor imaging study. Neuroreport 2001; 12: 2251-2254
2. Andreasen NC. Scale for the assessment of negative symptoms (SANS). Iowa City: University of Iowa; 1983.
3. Andrews-Hanna JR, Snyder AZ, Vincent JL, Lustig C, Head D, Raichle ME, et al. Disruption of large-scale brain systems in advanced aging. Neuron 2007; 56: 924-935
4. Ardekani BA, Nierenberg J, Hoptman MJ, Javitt DC, Lim KO. MRI study of white matter diffusion anisotropy in schizophrenia. Neuroreport 2003; 14: 2025-2029
5. Beaulieu C. The basis of anisotropic water diffusion in the nervous system-a technical review. NMR Biomed 2002; 15: 435-455
6. Benes FM. Neurobiological investigations in cingulate cortex of schizophrenic brain. Schizophr Bull 1993; 19: 537-549
7. Benes FM. Emerging principles of altered neural circuitry in schizophrenia. Brain Res Brain Res Rev 2000; 31: 251-269
8. Binder JR, Frost JA, Hammeke TA, Bellgowan PS, Rao SM, Cox RW. Conceptual processing during the conscious resting state. A functional MRI study. J Cogn Neurosci 1999; 11: 80-95.
9. Biswal B, Yetkin FZ, Haughton VM, Hyde JS. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 1995; 34: 537-541
10. Buchsbaum MS, Tang CY, Peled S, Gudbjartsson H, Lu D, Hazlett EA, et al. MRI white matter diffusion anisotropy and PET metabolic rate in schizophrenia. Neuroreport 1998; 9: 425-430
11. Buckner RL, Andrews-Hanna JR, Schacter DL. The brain's default network: anatomy, function, and relevance to disease. Ann N Y Acad Sci 2008; 1124: 1-38.
12. Buckner RL, Goodman J, Burock M, Rotte M, Koutstaal W, Schacter D, et al. Functional-anatomic correlates of object priming in humans revealed by rapid presentation event-related fMRI. Neuron 1998; 20: 285-296
13. Burns J, Job D, Bastin ME, Whalley H, Macgillivray T, Johnstone EC, et al. Structural disconnectivity in schizophrenia: a diffusion tensor magnetic resonance imaging study. Br J Psychiatry 2003; 182: 439-443
14. Burock MA, Dale AM. Estimation and detection of event-related fMRI signals with temporally correlated noise: a statistically efficient and unbiased approach. Hum Brain Mapp 2000; 11: 249-260
15. Bush G, Luu P, Posner MI. Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 2000; 4: 215-222
16. Bush G, Whalen PJ, Rosen BR, Jenike MA, McInerney SC, Rauch SL. The counting stroop: an interference task specialized for functional neuro-imaging-validation study with functional MRI. Hum Brain Mapp 1998; 6: 270-282
17. Calhoun VD, Eichele T, Pearlson G. Functional brain networks in schizophrenia: a review. Front Hum Neurosci 2009; 3: 17.
18. Calkins ME, Iacono WG, Curtis CE. Smooth pursuit and antisaccade performance evidence trait stability in schizophrenia patients and their relatives. Int J Psychophysiol 2003; 49: 139-146
19. Camchong J, Dyckman KA, Austin BP, Clementz BA, McDowell JE. Common neural circuitry supporting volitional saccades and its disruption in schizophrenia patients and relatives. Biol Psychiatry 2008; 64: 1042-1050
20. Chang C, Glover GH. Effects of model-based physiological noise correction on default mode network anti-correlations and correlations. Neuroimage 2009; 47: 1448-1459
21. Collins DL, Neelin P, Peters TM, Evans AC. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 1994; 18: 192-205.
22. Corbetta M, Shulman GL. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 2002; 3: 201-215
23. Cox RW, Jesmanowicz A. Real-time 3D image registration for functional MRI. Magn Reson Med 1999; 42: 1014-1018
24. Crawford TJ, Puri BK, Nijran KS, Jones B, Kennard C, Lewis SW. Abnormal saccadic distractibility in patients with schizophrenia: a 99mTc-HMPAO SPET study. Psychol Med 1996; 26: 265-277
25. Curtis CE, D'Esposito M. Success and failure suppressing reflexive behavior. J Cogn Neurosci 2003; 15: 409-418
26. Damoiseaux JS, Beckmann CF, Arigita EJ, Barkhof F, Scheltens P, Stam CJ, et al. Reduced resting-state brain activity in the "default network" in normal aging. Cereb Cortex 2008; 18: 1856-1864
27. Devinsky O, Morrell MJ, Vogt BA Contributions of anterior cingulate cortex to behaviour. Brain 1995; 118 (Pt 1): 279-306.
28. Drevets WC, Raichle ME. Reciprocal suppression of regional cerebral blood flow during emotional versus higher cognitive processes: implications for interactions between emotion and cognition. Cogn Emot 1998; 12: 353-385
29. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Axis I Disorders, Research Version, Patient Edition with Psychotic Screen (SCID-I/P W/PSY SCREEN). New York: Biometrics Research, New York State Psychiatric Institute; 1997.
30. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Nonpatient Edition. New York: Biometrics Research, New York State Psychiatric Institute; 2002.
31. Fischer B, Breitmeyer B. Mechanisms of visual attention revealed by saccadic eye movements. Neuropsychologia 1987; 25: 73-83.
32. Foong J, Symms MR, Barker GJ, Maier M, Miller DH, Ron MA. Investigating regional white matter in schizophrenia using diffusion tensor imaging. Neuroreport 2002; 13: 333-336
33. Fox MD, Raichle ME. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci 2007; 8: 700-711
34. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, Raichle ME. The human brain is intrinsically organized into dynamic, anti-correlated functional networks. Proc Natl Acad Sci USA 2005; 102: 9673-9678
35. Fransson P. How default is the default mode of brain function? Further evidence from intrinsic BOLD signal fluctuations. Neuropsychologia 2006; 44: 2836-2845
36. Garrity AG, Pearlson GD, McKiernan K, Lloyd D, Kiehl KA, Calhoun VD. Aberrant "default mode" functional connectivity in schizophrenia. Am J Psychiatry 2007; 164: 450-457
37. Gaymard B, Rivaud S, Cassarini JF, Dubard T, Rancurel G, Agid Y, et al. Effects of anterior cingulate cortex lesions on ocular saccades in humans. Exp Brain Res 1998; 120: 173-183
38. Gitelman DR, Nobre AC, Parrish TB, LaBar KS, Kim YH, Meyer JR, et al. A large-scale distributed network for covert spatial attention: further anatomical delineation based on stringent behavioural and cognitive controls. Brain 1999; 122: 1093-1106
39. Goldstein JM, Goodman JM, Seidman LJ, Kennedy DN, Makris N, Lee H, et al. Cortical abnormalities in schizophrenia identified by structural magnetic resonance imaging. Arch Gen Psychiatry 1999; 56: 537-547
40. Gooding DC, Basso MA. The tell-tale tasks: a review of saccadic research in psychiatric patient populations. Brain Cogn 2008; 68: 371-390
41. Greicius M. Resting-state functional connectivity in neuropsychiatric disorders. Curr Opin Neurol 2008; 21: 424-430
42. Gusnard DA, Raichle ME, Raichle ME. Searching for a baseline: functional imaging and the resting human brain. Nat Rev Neurosci 2001; 2: 685-694
43. Ha TH, Youn T, Ha KS, Rho KS, Lee JM, Kim IY, et al. Gray matter abnormalities in paranoid schizophrenia and their clinical correlations. Psychiatry Res 2004; 132: 251-260
44. Hallett PE. Primary and secondary saccades to goals defined by instructions. Vision Res 1978; 18: 1279-1296
45. Hao Y, Liu Z, Jiang T, Gong G, Liu H, Tan L, et al. White matter integrity of the whole brain is disrupted in first-episode schizophrenia. Neuroreport 2006; 17: 23-26
46. Harris MS, Reilly JL, Keshavan MS, Sweeney JA. Longitudinal studies of antisaccades in antipsychotic-naive first-episode schizophrenia. Psychol Med 2006; 36: 485-494
47. Harsan LA, Poulet P, Guignard B, Steibel J, Parizel N, de Sousa PL, et al. Brain dysmyelination and recovery assessment by noninvasive in vivo diffusion tensor magnetic resonance imaging. J Neurosci Res 2006; 83: 392-402.
48. Honey GD, Suckling J, Zelaya F, Long C, Routledge C, Jackson S, et al. Dopaminergic drug effects on physiological connectivity in a human cortico-striato-thalamic system. Brain 2003; 126: 1767-1781
49. Hunt AR, Kingstone A. Covert and overt voluntary attention: linked or independent? Brain Res Cogn Brain Res 2003; 18: 102-105
50. Isoda M, Hikosaka O. Switching from automatic to controlled action by monkey medial frontal cortex. Nat Neurosci 2007; 10: 240-248
51. Johnston K, Levin HM, Koval MJ, Everling S. Top-down control-signal dynamics in anterior cingulate and prefrontal cortex neurons following task switching. Neuron 2007; 53: 453-462
52. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987; 13: 261-276
53. Kim DI, Manoach DS, Mathalon DH, Turner JA, Mannell M, Brown GG, et al. Dysregulation of working memory and default-mode networks in schizophrenia using independent component analysis, an fBIRN and MCIC study. Hum Brain Mapp 2009; 30: 3795-3811
54. Klein R, McCormick P. Covert visual orienting: hemifield-activation can be mimicked by zoom lens and midlocation placement strategies. Acta Psychol 1989; 70: 235-250
55. Koski L, Paus T. Functional connectivity of the anterior cingulate cortex within the human frontal lobe: a brain-mapping meta-analysis. Exp Brain Res 2000; 133: 55-65.
56. Kubicki M, Westin CF, Nestor PG, Wible CG, Frumin M, Maier SE, et al. Cingulate fasciculus integrity disruption in schizophrenia: a magnetic resonance diffusion tensor imaging study. Biol Psychiatry 2003; 54: 1171-1180
57. Kuperberg GR, Broome MR, McGuire PK, David AS, Eddy M, Ozawa F, et al. Regionally localized thinning of the cerebral cortex in schizophrenia. Arch Gen Psychiatry 2003; 60: 878-888
58. Luck SJ, Gold JM. The construct of attention in schizophrenia. Biol Psychiatry 2008; 64: 34-39
59. Manoach DS, Ketwaroo GA, Polli FE, Thakkar KN, Barton JJ, Goff DC, et al. Reduced microstructural integrity of the white matter underlying anterior cingulate cortex is associated with increased saccadic latency in schizophrenia. Neuroimage 2007a; 37: 599-610.
60. Manoach DS, Lindgren KA, Cherkasova MV, Goff DC, Halpern EF, Intriligator J, et al. Schizophrenic subjects show deficient inhibition but intact task-switching on saccadic tasks. Biol Psychiatry 2002; 51: 816-826
61. Manoach DS, Thakkar KN, Cain MS, Polli FE, Edelman JA, Fischl B, et al. Neural activity is modulated by trial history: a functional magnetic resonance imaging study of the effects of a previous antisaccade. J Neurosci 2007b; 27: 1791-1798
62. Margulies DS, Kelly AM, Uddin LQ, Biswal BB, Castellanos FX, Milham MP. Mapping the functional connectivity of anterior cingulate cortex. Neuroimage 2007; 37: 579-588
63. Mazoyer B, Zago L, Mellet E, Bricogne S, Etard O, Houde O, et al. Cortical networks for working memory and executive functions sustain the conscious resting state in man. Brain Res Bull 2001; 54: 287-298
64. McDonald C, Bullmore E, Sham P, Chitnis X, Suckling J, MacCabe J, et al. Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder: computational morphometry study. Br J Psychiatry 2005; 186: 369-377
65. McDowell JE, Clementz BA. Behavioral and brain imaging studies of saccadic performance in schizophrenia. Biol Psychol 2001; 57: 5-22.
66. Mesulam M.-M. A cortical network for directed attention and unilateral neglect. Ann Neurol 1981; 10: 309-325
67. Mesulam MM. Large-scale neurocognitive networks and distributed processing for attention, language, and memory. Ann Neurol 1990; 28: 597-613.
68. Miezin FM, Maccotta L, Ollinger JM, Petersen SE, Buckner RL. Characterizing the hemodynamic response: effects of presentation rate, sampling procedure, and the possibility of ordering brain activity based on relative timing. Neuroimage 2000; 11: 735-759
69. Milea D, Lehericy S, Rivaud-Pechoux S, Duffau H, Lobel E, Capelle L, et al. Antisaccade deficit after anterior cingulate cortex resection. Neuroreport 2003; 14: 283-287
70. Miller EK, Cohen JD. An integrative theory of prefrontal cortex function. Annu Rev Neurosci 2001; 24: 167-202.
71. Miller LM, Sun FT, Curtis CE, D'Esposito M. Functional interactions between oculomotor regions during prosaccades and antisaccades. Hum Brain Mapp 2005; 26: 119-127
72. Mitelman SA, Shihabuddin L, Brickman AM, Hazlett EA, Buchsbaum MS. Volume of the cingulate and outcome in schizophrenia. Schizophr Res 2005; 72: 91-108.
73. Mitz AR, Godschalk M. Eye-movement representation in the frontal lobe of rhesus monkeys. Neurosci Lett 1989; 106: 157-162
74. Moore T, Armstrong KM, Fallah M. Visuomotor origins of covert spatial attention. Neuron 2003; 40: 671-683
75. Morecraft RJ, Geula C, Mesulam MM. Architecture of connectivity within a cingulo-fronto-parietal neurocognitive network for directed attention. Arch Neurol 1993; 50: 279-284
76. Munoz DP, Broughton JR, Goldring JE, Armstrong IT. Age-related performance of human subjects on saccadic eye movement tasks. Exp Brain Res 1998; 121: 391-400.
77. Murphy K, Birn RM, Handwerker DA, Jones TB, Bandettini PA. The impact of global signal regression on resting state correlations: are anti-correlated networks introduced? Neuroimage 2009; 44: 893-905.
78. Nachev P, Kennard C, Husain M. Functional role of the supplementary and pre-supplementary motor areas Nat Rev Neurosci 2008; 9: 856-869
79. Ohnuma T, Kimura M, Takahashi T, Iwamoto N, Arai H. A magnetic resonance imaging study in first-episode disorganized-type patients with schizophrenia. Psychiatry Clin Neurosci 1997; 51: 9-15.
80. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971; 9: 97-113.
81. Overall JE, Gorham DR. The brief psychiatric rating scale. Psychol Reports 1962; 10: 799-812.
82. Pandya DN, Van Hoesen GW, Mesulam MM. Efferent connections of the cingulate gyrus in the rhesus monkey. Exp Brain Res 1981; 42: 319-330
83. Paus T, Petrides M, Evans AC, Meyer E. Role of the human anterior cingulate cortex in the control of oculomotor, manual, and speech responses: a positron emission tomography study. J Neurophysiol 1993; 70: 453-469
84. Pierrot-Deseilligny C, Milea D, Muri RM. Eye movement control by the cerebral cortex. Curr Opin Neurol 2004; 17: 17-25.
85. Polli FE, Barton JJ, Cain MS, Thakkar KN, Rauch SL, Manoach DS. Rostral and dorsal anterior cingulate cortex make dissociable contributions during antisaccade error commission. Proc Natl Acad Sci USA 2005; 102: 15700-15705
86. Polli FE, Barton JJ, Thakkar KN, Greve DN, Goff DC, Rauch SL, et al. Reduced error-related activation in two anterior cingulate circuits is related to impaired performance in schizophrenia. Brain 2008; 131: 971-986
87. Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, et al. Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophr Res 2007; 89: 320-329
88. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL. A default mode of brain function. Proc Natl Acad Sci USA 2001; 98: 676-682
89. Sambataro F, Murty VP, Callicott JH, Tan HY, Das S, Weinberger DR, et al. Age-related alterations in default mode network: Impact on working memory performance. Neurobiol Aging 2008 (in press).
90. Shulman GI, Fiez JA, Corbetta M, Buckner RL, Miezin FM, Raichle ME, et al. Common blood flow changes across visual tasks: II. Decreases in cerebral cortex. J Cog Neurosci 1997; 9: 648-663
91. Sigmundsson T, Suckling J, Maier M, Williams S, Bullmore E, Greenwood K, et al. Structural abnormalities in frontal, temporal, and limbic regions and interconnecting white matter tracts in schizophrenic patients with prominent negative symptoms. Am J Psychiatry 2001; 158: 234-243
92. Sun Z, Wang F, Cui L, Breeze J, Du X, Wang X, et al. Abnormal anterior cingulum in patients with schizophrenia: A diffusion tensor imaging study. Neuroreport 2003; 14: 1833-1836 (Pubitemid 37372613)
93. Suzuki M, Nohara S, Hagino H, Kurokawa K, Yotsutsuji T, Kawasaki Y, et al. Regional changes in brain gray and white matter in patients with schizophrenia demonstrated with voxel-based analysis of MRI. Schizophr Res 2002; 55: 41-54.
94. Thesen S, Heid O, Mueller E, Schad LR. Prospective acquisition correction for head motion with image-based tracking for real-time fMRI. Magn Reson Med 2000; 44: 457-465
95. Van Dijk KRA, Hedden T, Venkataraman A, Evans KC, Lazar SW, Buckner RL. Functional connectivity MRI: Theory, properties, and optimization. J Neurophys 2010 (Epub before print).
96. Vincent JL, Snyder AZ, Fox MD, Shannon BJ, Andrews JR, Raichle ME, et al. Coherent spontaneous activity identifies a hippocampal-parietal memory network. J Neurophysiol 2006; 96: 3517-3531
97. Vogt BA, Rosene DL, Pandya DN. Thalamic and cortical afferents differentiate anterior from posterior cingulate cortex in the monkey. Science 1979; 204: 205-207
98. Wang F, Sun Z, Cui L, Du X, Wang X, Zhang H, et al. Anterior cingulum abnormalities in male patients with schizophrenia determined through diffusion tensor imaging. Am J Psychiatry 2004; 161: 573-575
99. Whalen PJ, Bush G, McNally RJ, Wilhelm S, McInerney SC, Jenike MA, et al. The emotional counting Stroop paradigm: a functional magnetic resonance imaging probe of the anterior cingulate affective division. Biol Psychiatry 1998; 44: 1219-1228
100. White K, Ashton R. Handedness assessment inventory. Neuropsychologia 1976; 14: 261-264
101. Whitfield-Gabrieli S, Thermenos HW, Milanovic S, Tsuang MT, Faraone SV, McCarley RW, et al. Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proc Natl Acad Sci USA 2009; 106: 1279-1284
102. Woods SW. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry 2003; 64: 663-667
103. Yamasue H, Iwanami A, Hirayasu Y, Yamada H, Abe O, Kuroki N, et al. Localized volume reduction in prefrontal, temporolimbic, and paralim-bic regions in schizophrenia: an MRI parcellation study. Psychiatry Res 2004; 131: 195-207.